Skip to main content

Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,564
−28 vs. Q1 2025
Shares held
240.9M
+1.26M (+0.5%) vs. Q1 2025
Total value
$107.2B
−$8.95B (−7.7%) vs. Q1 2025
New holders
121
619 more added
Sold out
149
608 more reduced

26 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 1,564 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ2 2025: $107.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2025.

Institutions holding VRTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Sanibel Captiva Trust Company, Inc.617$274.7K0.01%−42−6.4%Reduced
MONECO Advisors, LLC619$275.8K0.03%00.0%Unchanged
Western Wealth Management, LLC621$276.5K0.02%−70−10.1%Reduced
Mesirow Financial Investment Management, Inc.624$277.8K0.01%−5−0.8%Reduced
Financial Engines Advisors L.L.C.625$278.0K0.00%+625New
AA Financial Advisors, LLC632$281.4K0.06%+632New
Cim, LLC633$281.8K0.04%+158+33.3%Added
Syverson Strege & Co635$282.7K0.07%+635New
Relyea Zuckerberg Hanson LLC637$283.6K0.03%−125−16.4%Reduced
Inscription Capital, LLC641$285.4K0.04%+79+14.1%Added
Cromwell Holdings LLC656$292.1K0.18%+16+2.5%Added
Sivia Capital Partners, LLC657$292.5K0.10%−69−9.5%Reduced
Alpha Zero LLC661$294.3K0.19%+56+9.3%Added
Kempen Capital Management N.V.663$295.2K0.00%−35−5.0%Reduced
Onefund, LLC668$297.0K0.21%−9−1.3%Reduced
Stanley-Laman Group, Ltd.668$297.4K0.04%−334−33.3%Reduced
Capital Market Strategies LLC670$298.3K0.21%−350−34.3%Reduced
KC Investment Advisors, LLC672$299.2K0.10%−1−0.1%Reduced
May Hill Capital, LLC673$299.6K0.10%+40+6.3%Added
Versant Capital Management, Inc674$300.1K0.05%+47+7.5%Added
Driehaus Capital Management LLC677$301.4K0.00%−431−38.9%Reduced
Zullo Investment Group, Inc.677$301.4K0.12%−126−15.7%Reduced
Perpetual Ltd679$302.3K0.00%+56+9.0%Added
Guerra Pan Advisors, LLC680$302.7K0.20%+86+14.5%Added
Ewa, LLC681$303.2K0.10%+97+16.6%Added
Cullen/Frost Bankers, Inc.682$303.6K0.00%−345−33.6%Reduced
William Mack & Associates, Inc.682$303.6K0.19%00.0%Unchanged
Fox Hill Wealth Management683$304.1K0.16%+6+0.9%Added
Costello Asset Management, INC689$306.7K0.12%+24+3.6%Added
GK Wealth Management LLC689$306.7K0.30%+689New
HBK Sorce Advisory LLC690$307.2K0.01%+96+16.2%Added
Fairfield, Bush & Co.691$307.6K0.17%00.0%Unchanged
Venture Visionary Partners LLC694$309.0K0.01%+5+0.7%Added
Nautilus Advisors LLC701$312.1K0.23%+235+50.4%Added
Essex Savings Bank704$313.4K0.07%+13+1.9%Added
One Charles Private Wealth Services, LLC704$313.4K0.09%+704New
Meridian Wealth Management, LLC707$314.8K0.01%+87+14.0%Added
Grimes & Company, Inc.708$315.1K0.01%+2+0.3%Added
Fort Point Capital Partners LLC708$315.2K0.03%+34+5.0%Added
FourThought Financial Partners, LLC711$316.5K0.03%+50+7.6%Added
Investment Advisory Group, LLC712$317.0K0.10%−5−0.7%Reduced
Seven Mile Advisory712$317.0K0.19%+3+0.4%Added
Sage Capital Advisors,llc715$318.1K0.08%+114+19.0%Added
Leeward Financial Partners, LLC716$318.8K0.10%+58+8.8%Added
Putney Financial Group LLC719$320.1K0.32%−196−21.4%Reduced
Wedgewood Investors Inc720$320.5K0.37%00.0%Unchanged
Castleark Management LLC730$325.0K0.01%−46,309−98.4%Reduced
Nicholas Hoffman & Company, LLC.732$325.9K0.01%00.0%Unchanged
Bourgeon Capital Management LLC735$327.2K0.06%−632−46.2%Reduced
Norris Financial Group, LLC736$327.7K0.13%+736New
Regions Financial Corp737$328.1K0.00%+30+4.2%Added
Mitchell McLeod Pugh & Williams Inc742$330.3K0.06%+230+44.9%Added
Loring Wolcott & Coolidge Fiduciary Advisors LLP744$331.2K0.00%+50+7.2%Added
Abundance Wealth Counselors746$332.0K0.06%+100+15.5%Added
Northstar Asset Management LLC750$333.9K0.08%00.0%Unchanged
Moss Adams Wealth Advisors LLC751$334.5K0.03%−112−13.0%Reduced
Financial Symmetry Inc755$336.3K0.17%00.0%Unchanged
Pinnacle Wealth Management Advisory Group, LLC757$337.0K0.03%+26+3.6%Added
MUFG Securities EMEA plc757$337.0K0.02%+757New
Childress Capital Advisors, LLC760$338.5K0.09%−40−5.0%Reduced
denkapparat Operations GmbH766$341.0K0.27%−460−37.5%Reduced
One Capital Management, LLC766$341.0K0.01%+204+36.3%Added
Ausdal Financial Partners, Inc.770$342.8K0.02%−10−1.3%Reduced
Essex Financial Services, Inc.772$343.7K0.02%−5−0.6%Reduced
Turtle Creek Wealth Advisors, LLC777$345.9K0.04%+777New
Banque Transatlantique SA776$346.3K0.01%−48−5.8%Reduced
Cercano Management LLC780$347.3K0.01%00.0%Unchanged
Newman Dignan & Sheerar, Inc.786$349.9K0.08%+25+3.3%Added
Delta Financial Advisors LLC788$350.8K0.12%+106+15.5%Added
ICONIQ Capital, LLC790$351.7K0.01%−450−36.3%Reduced
Everpar Advisors LLC792$352.6K0.16%+44+5.9%Added
Zhang Financial LLC792$352.8K0.02%−524−39.8%Reduced
Boston Family Office LLC796$354.0K0.02%+345+76.5%Added
Soltis Investment Advisors LLC796$354.2K0.03%−89−10.1%Reduced
Parsonex Advisory Services, Inc.800$356.2K0.30%+800New
One Wealth Capital Management, LLC803$357.5K0.17%+21+2.7%Added
Stock Yards Bank & Trust Co809$360.2K0.01%+295+57.4%Added
Larson Financial Group LLC811$361.1K0.01%−25−3.0%Reduced
LVW Advisors, LLC813$361.9K0.04%+19+2.4%Added
Founders Financial Alliance, LLC819$364.6K0.08%−49−5.6%Reduced
Opinicus Capital, Inc.822$366.0K0.28%+3+0.4%Added
WSFS Capital Management, LLC826$367.7K0.02%+370+81.1%Added
Ancora Advisors, LLC836$372.3K0.01%−2−0.2%Reduced
BridgePort Financial Solutions, LLC843$375.3K0.12%+50+6.3%Added
Fulton Bank, N.A.847$377.1K0.01%+274+47.8%Added
Sentry Investment Management LLC821$383.0K0.21%00.0%Unchanged
Lockerman Financial Group, Inc.863$384.2K0.52%+15+1.8%Added
Severin Investments, LLC867$385.8K0.36%−12−1.4%Reduced
Pinnacle Wealth Planning Services, Inc.868$386.4K0.05%−218−20.1%Reduced
Douglass Winthrop Advisors, LLC868$386.4K0.01%00.0%Unchanged
Prescott Group Capital Management, L.L.C.869$386.9K0.05%+272+45.6%Added
George Kaiser Family Foundation869$386.9K0.06%+272+45.6%Added
Ellevest, Inc.877$390.4K0.06%−231−20.8%Reduced
Portfolio Design Labs, LLC880$391.8K0.08%−856−49.3%Reduced
Wealthspire Advisors, LLC881$392.1K0.00%+151+20.7%Added
Forza Wealth Management, LLC881$392.2K0.16%00.0%Unchanged
Parkside Financial Bank & Trust884$393.6K0.04%00.0%Unchanged
Arthur M. Cohen & Associates, LLC890$396.2K0.07%00.0%Unchanged
YHB Investment Advisors, Inc.891$396.7K0.03%−50−5.3%Reduced
Ramiah Investment Group893$397.6K0.43%−254−22.1%Reduced