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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,564
−28 vs. Q1 2025
Shares held
240.9M
+1.26M (+0.5%) vs. Q1 2025
Total value
$107.2B
−$8.95B (−7.7%) vs. Q1 2025
New holders
121
619 more added
Sold out
149
608 more reduced

26 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 1,564 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ2 2025: $107.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2025.

Institutions holding VRTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Ignite Planners, LLC462$212.4K0.04%−145−23.9%Reduced
Clark Capital Management Group, Inc.481$214.0K0.00%−12−2.4%Reduced
Acropolis Investment Management, LLC482$214.6K0.01%+6+1.3%Added
Farmers & Merchants Trust Co of Long Beach484$215.5K0.05%+58+13.6%Added
Axq Capital, LP484$215.5K0.07%+484New
Boston Trust Walden Corp485$215.9K0.00%−125−20.5%Reduced
Roberts Capital Advisors, LLC485$215.9K0.16%−89−15.5%Reduced
Loudon Investment Management, LLC485$215.9K0.12%00.0%Unchanged
Private Wealth Asset Management, LLC487$216.8K0.03%+9+1.9%Added
Waters Parkerson & Co., LLC489$217.7K0.01%00.0%Unchanged
Salem Investment Counselors Inc494$219.9K0.01%+174+54.4%Added
Lewis Asset Management, LLC495$220.4K0.10%−250−33.6%Reduced
Beaumont Financial Advisors, LLC496$220.8K0.02%+5+1.0%Added
International Assets Investment Management, LLC498$221.7K0.02%−55−9.9%Reduced
Columbia Asset Management498$221.7K0.04%+498New
Kingsview Wealth Management, LLC499$222.2K0.00%−46−8.4%Reduced
GM Advisory Group, Inc.499$222.2K0.01%−14−2.7%Reduced
Arlington Financial Advisors, LLC500$222.6K0.04%−40−7.4%Reduced
McHugh Group, LLC500$222.6K0.15%00.0%Unchanged
Mengis Capital Management, Inc.500$222.6K0.05%+500New
Centurion Wealth Management LLC501$223.0K0.06%+501New
Advus Financial Partners, LLC502$223.5K0.06%+19+3.9%Added
Smithfield Trust Co503$224.0K0.01%00.0%Unchanged
Morris Financial Concepts, Inc.504$224.4K0.09%−10−1.9%Reduced
DGS Capital Management, LLC504$224.4K0.05%+504New
Diversified Enterprises, LLC505$224.8K0.02%−42−7.7%Reduced
Manchester Capital Management LLC506$225.3K0.03%−20−3.8%Reduced
Trinity Legacy Partners, LLC480$225.4K0.05%00.0%Unchanged
US Asset Management LLC507$225.7K0.20%00.0%Unchanged
MBB Public Markets I LLC510$227.1K0.03%−116−18.5%Reduced
Montag A & Associates Inc510$227.1K0.01%+25+5.2%Added
Gamco Investors, Inc. Et Al512$227.9K0.00%+512New
Nvest Financial, LLC513$228.4K0.12%+14+2.8%Added
BLB&B Advisors, LLC514$228.8K0.01%00.0%Unchanged
First Foundation Advisors515$229.3K0.01%+515New
Teamwork Financial Advisors, LLC519$231.1K0.03%−204−28.2%Reduced
VisionPoint Advisory Group, LLC520$231.5K0.05%+520New
Abel Hall, LLC521$231.9K0.11%−47−8.3%Reduced
Five Oceans Advisors523$232.8K0.10%−1−0.2%Reduced
Integral Investment Advisors, Inc.525$233.7K0.07%+19+3.8%Added
Carr Financial Group Corp528$235.1K0.07%−80−13.2%Reduced
Marshall Financial Group LLC512$235.2K0.05%−136−21.0%Reduced
Boothbay Fund Management, LLC530$236.0K0.01%−146−21.6%Reduced
KMG Fiduciary Partners, LLC531$236.4K0.02%+20+3.9%Added
Stonebrook Private Inc.532$236.8K0.06%+532New
AGH Wealth Advisors, LLC536$238.6K0.20%−4−0.7%Reduced
Tillman Hartley LLC536$238.6K0.07%00.0%Unchanged
BCJ Capital Management, LLC536$238.6K0.02%+23+4.5%Added
Elyxium Wealth, LLC539$239.9K0.09%+103+23.6%Added
UMA Financial Services, Inc.541$240.9K0.04%+3+0.6%Added
MBL Wealth, LLC542$241.3K0.02%−11−2.0%Reduced
Whittier Trust Co of Nevada Inc544$242.2K0.01%−8−1.4%Reduced
PFW Advisors LLC545$242.6K0.07%−256−32.0%Reduced
Davy Global Fund Management Ltd545$242.6K0.02%+545New
Facet Wealth, Inc.533$243.5K0.01%+533New
Empower Advisory Group, LLC549$244.4K0.00%−86−13.5%Reduced
Custom Index Systems, LLC550$244.9K0.12%−77−12.3%Reduced
Fielder Capital Group LLC553$246.2K0.07%+20+3.8%Added
Monetary Management Group Inc555$247.1K0.06%00.0%Unchanged
IFC Advisors LLC555$247.1K0.05%00.0%Unchanged
FSM Wealth Advisors, LLC538$247.3K0.04%−6−1.1%Reduced
Kingswood Wealth Advisors, LLC557$248.0K0.02%+1+0.2%Added
Massachusetts Wealth Management560$249.3K0.14%−37−6.2%Reduced
Vanguard Capital Wealth Advisors560$249.3K0.25%00.0%Unchanged
Pinebridge Investments, L.P.562$250.2K0.00%−13,634−96.0%Reduced
LRI Investments, LLC562$250.2K0.02%−170−23.2%Reduced
Green Alpha Advisors, LLC565$251.5K0.24%−103−15.4%Reduced
Asset Allocation & Management Company, LLC567$252.0K0.12%00.0%Unchanged
Heartwood Wealth Advisors LLC568$252.9K0.03%+30+5.6%Added
Global Trust Asset Management, LLC568$253.1K0.14%−65−10.3%Reduced
TBH Global Asset Management, LLC569$253.3K0.05%−44−7.2%Reduced
Hanson & Doremus Investment Management570$254.0K0.03%+200+54.1%Added
Midwest Trust Co571$254.2K0.00%+571New
RFG Advisory, LLC571$254.3K0.01%−186−24.6%Reduced
Cura Wealth Advisors, LLC575$256.0K0.12%+575New
Independence Bank of Kentucky576$256.4K0.04%+47+8.9%Added
JGP Global Gestao de Recursos Ltda.581$258.7K0.13%−2−0.3%Reduced
Bartlett & Co. Wealth Management LLC587$261.3K0.00%00.0%Unchanged
Whipplewood Advisors, LLC589$262.2K0.14%+5+0.9%Added
Icapital Wealth LLC591$263.1K0.15%00.0%Unchanged
Ronald Blue Trust, Inc.592$263.6K0.00%+19+3.3%Added
Lion Street Advisors, LLC592$263.6K0.08%−2−0.3%Reduced
United Advisor Group, LLC594$264.4K0.05%+594New
Chesley Taft & Associates LLC596$265.3K0.01%+110+22.6%Added
Keudell/Morrison Wealth Management597$265.8K0.06%−45−7.0%Reduced
Corient IA LLC600$267.1K0.16%−100−14.3%Reduced
McAdam, LLC600$267.1K0.01%+84+16.3%Added
Capital Performance Advisors LLP601$267.5K0.05%+59+10.9%Added
Tritonpoint Wealth, LLC601$267.6K0.02%−3−0.5%Reduced
ICW Investment Advisors LLC604$268.7K0.11%+29+5.0%Added
Kelly Lawrence W & Associates Inc605$269.3K0.07%00.0%Unchanged
Aries Wealth Management605$269.3K0.07%00.0%Unchanged
Focus Financial Network, Inc.606$269.8K0.01%+33+5.8%Added
Resurgent Financial Advisors LLC607$270.2K0.15%+6+1.0%Added
ASB Consultores, LLC608$270.7K0.18%+32+5.6%Added
Warren Street Wealth Advisors, LLC609$271.1K0.09%+100+19.6%Added
Diversified Trust Co613$272.9K0.01%−19−3.0%Reduced
First American Bank614$273.4K0.02%00.0%Unchanged
Sittner & Nelson, LLC615$273.8K0.11%+17+2.8%Added
Nicolet Bankshares Inc617$274.7K0.05%00.0%Unchanged