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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,564
−28 vs. Q1 2025
Shares held
240.9M
+1.26M (+0.5%) vs. Q1 2025
Total value
$107.2B
−$8.95B (−7.7%) vs. Q1 2025
New holders
121
619 more added
Sold out
149
608 more reduced

26 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 1,564 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ2 2025: $107.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2025.

Institutions holding VRTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Gables Capital Management Inc.121$53.9K0.03%00.0%Unchanged
Smallwood Wealth Investment Management, LLC121$53.9K0.03%00.0%Unchanged
Activest Wealth Management122$54.1K0.01%+71+139.2%Added
Atlantic Edge Private Wealth Management, LLC125$55.6K0.02%00.0%Unchanged
Raleigh Capital Management Inc.131$58.3K0.02%−342−72.3%Reduced
Core Alternative Capital131$58.3K0.02%00.0%Unchanged
Truvestments Capital LLC136$60.5K0.01%+40+41.7%Added
REAP Financial Group, LLC137$61.0K0.01%+77+128.3%Added
Union Bancaire Privee, UBP SA139$61.3K0.00%00.0%Unchanged
Financial Avengers, Inc.140$62.3K0.03%00.0%Unchanged
Centricity Wealth Management, LLC141$62.8K0.05%00.0%Unchanged
Atticus Wealth Management, LLC143$63.7K0.02%+3+2.1%Added
St Germain D J Co Inc145$64.6K0.00%00.0%Unchanged
Sierra Ocean, LLC146$65.0K0.05%+2+1.4%Added
Beacon Capital Management, LLC150$66.8K0.01%−31−17.1%Reduced
Chelsea Counsel Co150$66.8K0.03%00.0%Unchanged
Catalyst Capital Advisors LLC157$69.9K0.00%−45−22.3%Reduced
PFS Partners, LLC158$70.3K0.04%00.0%Unchanged
Boreal Capital Management LLC159$70.8K0.06%+159New
Caitong International Asset Management Co., Ltd160$71.2K0.05%+160New
GW&K Investment Management, LLC161$72.0K0.00%+18+12.6%Added
Valley National Advisers Inc164$73.0K0.01%−1−0.6%Reduced
Opal Wealth Advisors, LLC164$73.0K0.02%−5−3.0%Reduced
Oakworth Capital, Inc.164$73.0K0.00%−3−1.8%Reduced
Rise Advisors, LLC166$73.9K0.03%−1−0.6%Reduced
Farmers & Merchants Investments Inc166$73.9K0.00%+5+3.1%Added
MCF Advisors LLC167$74.3K0.00%00.0%Unchanged
Atlantic Trust, LLC173$77.0K0.01%+9+5.5%Added
Rosenberg Matthew Hamilton173$77.0K0.02%+21+13.8%Added
1620 Investment Advisors, Inc.181$80.6K0.06%−2−1.1%Reduced
Ofi Invest Asset Management214$81.2K0.00%−6,381−96.8%Reduced
Zions Bancorporation, National Association186$82.8K0.00%−227−55.0%Reduced
Edmond de Rothschild Holding S.A.191$85.0K0.00%−23−10.7%Reduced
MV Capital Management, Inc.196$87.3K0.01%−210−51.7%Reduced
TruNorth Capital Management, LLC200$89.0K0.02%00.0%Unchanged
Moisand Fitzgerald Tamayo, LLC200$89.0K0.01%00.0%Unchanged
Colonial Trust Advisors210$93.5K0.01%00.0%Unchanged
Crews Bank & Trust212$94.4K0.01%00.0%Unchanged
Plante Moran Financial Advisors, LLC219$97.5K0.01%+28+14.7%Added
Toth Financial Advisory Corp230$102.4K0.01%00.0%Unchanged
Trust Co of Vermont231$102.8K0.00%−131−36.2%Reduced
Rossby Financial, LCC239$106.4K0.04%+20+9.1%Added
Antipodes Partners Ltd241$107.3K0.00%−14−5.5%Reduced
Trust Co of Toledo NA244$108.6K0.01%+244New
Barnes Dennig Private Wealth Management LLC251$111.7K0.13%+223+796.4%Added
ORG Partners LLC250$113.0K0.02%+37+17.4%Added
Golden State Wealth Management, LLC256$114.0K0.01%+161+169.5%Added
Twin Peaks Wealth Advisors, LLC306$118.7K0.04%+306New
Hilltop National Bank272$121.1K0.03%+272New
Asset Dedication, LLC275$122.4K0.01%+71+34.8%Added
Roble, Belko & Company, Inc279$124.0K0.02%00.0%Unchanged
Park Place Capital Corp276$124.8K0.03%00.0%Unchanged
Ritter Daniher Financial Advisory LLC282$125.5K0.03%00.0%Unchanged
Cary Street Partner Investment Advisory LLC282$125.5K0.06%+9+3.3%Added
Key Financial Inc290$129.1K0.03%00.0%Unchanged
WPG Advisers, LLC293$130.4K0.11%−3−1.0%Reduced
Covestor Ltd298$133.0K0.08%+12+4.2%Added
T. Rowe Price Investment Management, Inc.297$133.0K0.00%+297New
Ameritas Advisory Services, LLC302$134.4K0.01%+302New
Arlington Trust Co LLC307$136.7K0.03%+3+1.0%Added
Hemington Wealth Management309$137.0K0.02%−7−2.2%Reduced
Clean Yield Group322$143.4K0.04%−4−1.2%Reduced
Alpine Bank Wealth Management322$143.4K0.02%+112+53.3%Added
TFC Financial Management323$143.8K0.02%00.0%Unchanged
Washington Trust Advisors, Inc.323$143.8K0.01%+25+8.4%Added
Walleye Capital LLC332$147.8K0.00%−3,071−90.2%Reduced
Mount Yale Investment Advisors, LLC333$148.3K0.01%+333New
Deseret Mutual Benefit Administrators334$148.7K0.07%00.0%Unchanged
Addison Advisors LLC343$152.7K0.04%−16−4.5%Reduced
Paradigm Asset Management Co LLC350$155.8K0.04%−100−22.2%Reduced
NBC Securities, Inc.360$160.0K0.01%+15+4.3%Added
Silver Oak Securities, Inc381$169.6K0.01%+381New
CVA Family Office, LLC382$170.1K0.02%−45−10.5%Reduced
Crewe Advisors LLC392$174.5K0.02%−7−1.8%Reduced
Park Square Financial Group, LLC398$177.2K0.13%00.0%Unchanged
Goodman Advisory Group, LLC400$178.1K0.06%−44−9.9%Reduced
Harbour Investments, Inc.403$179.4K0.00%−7−1.7%Reduced
Rothschild Investment LLC413$183.9K0.01%+4+1.0%Added
Johnson Financial Group, Inc.424$188.8K0.01%−660−60.9%Reduced
Foster & Motley Inc451$201.0K0.01%00.0%Unchanged
Daymark Wealth Partners, LLC452$201.2K0.01%−15−3.2%Reduced
Joel Isaacson & Co., LLC454$202.1K0.01%00.0%Unchanged
Stratos Wealth Advisors, LLC454$202.1K0.01%+27+6.3%Added
Quest Partners LLC455$202.6K0.02%+72+18.8%Added
Adirondack Trust Co457$203.4K0.07%−4−0.9%Reduced
Foster Group, Inc.462$205.7K0.01%−63−12.0%Reduced
Mainsail Asset Management, LLC462$205.7K0.13%00.0%Unchanged
Commonwealth Financial Services, LLC462$205.8K0.04%−3−0.6%Reduced
Haverford Trust Co463$206.1K0.00%+463New
Aprio Wealth Management, LLC463$206.1K0.02%+463New
Grove Bank & Trust465$207.0K0.03%−15−3.1%Reduced
PKS Advisory Services, LLC465$207.0K0.05%+465New
Klingman & Associates, LLC466$207.5K0.01%+466New
PFG Advisors466$207.5K0.01%+466New
Sound Income Strategies, LLC470$209.2K0.01%+2+0.4%Added
Blue Barn Wealth, LLC470$209.2K0.10%+38+8.8%Added
Sage Capital Management, LLC472$210.1K0.10%00.0%Unchanged
Eagle Wealth Strategies LLC473$210.6K0.12%−71−13.1%Reduced
SeaCrest Wealth Management, LLC474$211.0K0.02%−289−37.9%Reduced
Quent Capital, LLC475$211.5K0.02%−38−7.4%Reduced