Vertex Pharmaceuticals Inc
VRTX- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0000875320
No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.
13F holders, Q2 2025
Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 1,563
- −28 vs. Q1 2025
- Shares held
- 240.9M
- +1.26M (+0.5%) vs. Q1 2025
- Total value
- $107.2B
- −$8.95B (−7.7%) vs. Q1 2025
- New holders
- 121
- 618 more added
- Sold out
- 149
- 608 more reduced
26 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 1,762 | $119.7B |
| Q1 2026 | 1,698 | $106.1B |
| Q4 2025 | 1,671 | $109.5B |
| Q3 2025 | 1,523 | $90.8B |
| Q2 2025 | 1,563 | $107.2B |
| Q1 2025 | 1,617 | $116.3B |
| Q4 2024 | 1,563 | $95.2B |
| Q3 2024 | 1,551 | $109.1B |
| Q2 2024 | 1,551 | $109.9B |
| Q1 2024 | 1,497 | $98.0B |
| Q4 2023 | 1,442 | $95.7B |
| Q3 2023 | 1,280 | $81.9B |
| Q2 2023 | 1,287 | $83.3B |
| Q1 2023 | 1,212 | $75.0B |
| Q4 2022 | 1,224 | $68.3B |
| Q3 2022 | 1,127 | $68.5B |
| Q2 2022 | 1,109 | $66.1B |
| Q1 2022 | 1,072 | $60.9B |
| Q4 2021 | 1,034 | $50.4B |
| Q3 2021 | 936 | $41.9B |
| Q2 2021 | 979 | $46.8B |
| Q1 2021 | 1,000 | $50.6B |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Neuberger Berman Group LLC | 459,150 | $204.4M | 0.16% | +16,522+3.7% | Added |
| TD Asset Management Inc | 465,173 | $207.1M | 0.18% | −20,683−4.3% | Reduced |
| Lazard Asset Management LLC | 480,310 | $213.8M | 0.29% | −52,287−9.8% | Reduced |
| National Pension Service | 497,800 | $221.6M | 0.19% | −61,129−10.9% | Reduced |
| Raymond James Financial Inc | 499,777 | $222.5M | 0.08% | −10,765−2.1% | Reduced |
| DekaBank Deutsche Girozentrale | 506,457 | $223.5M | 0.40% | +15,328+3.1% | Added |
| Franklin Resources Inc | 523,833 | $233.2M | 0.06% | −178,201−25.4% | Reduced |
| Mitsubishi UFJ Kokusai Asset Management Co., Ltd. | 524,925 | $233.7M | 0.19% | +35,858+7.3% | Added |
| BNP Paribas Arbitrage, SA | 531,188 | $236.5M | 0.18% | −57,149−9.7% | Reduced |
| American Century Companies Inc | 538,132 | $239.6M | 0.13% | +72,391+15.5% | Added |
| Natixis Advisors, L.P. | 540,530 | $240.6M | 0.38% | −60,657−10.1% | Reduced |
| Manufacturers Life Insurance Company, The | 546,956 | $243.5M | 0.22% | +520.0% | Added |
| Dimensional Fund Advisors LP | 596,227 | $265.4M | 0.06% | −9,652−1.6% | Reduced |
| Citigroup Inc | 599,079 | $266.7M | 0.19% | −28,636−4.6% | Reduced |
| HSBC Holdings PLC | 641,961 | $285.7M | 0.18% | −202,714−24.0% | Reduced |
| Artisan Partners Limited Partnership | 650,259 | $289.5M | 0.43% | −68,872−9.6% | Reduced |
| Sumitomo Mitsui Trust Holdings, Inc. | 655,050 | $291.6M | 0.18% | +11,063+1.7% | Added |
| Voya Investment Management LLC | 699,644 | $310.9M | 0.31% | −127,494−15.4% | Reduced |
| UBS Group AG | 700,002 | $311.6M | 0.07% | −37,416−5.1% | Reduced |
| Wells Fargo & Company | 702,052 | $312.6M | 0.07% | −4,117−0.6% | Reduced |
| Harding Loevner LP | 711,611 | $316.8M | 2.13% | +13,152+1.9% | Added |
| California Public Employees Retirement System | 725,055 | $322.8M | 0.21% | −84,179−10.4% | Reduced |
| Pictet Asset Management Holding SA | 735,822 | $327.0M | 0.33% | +74,635+11.3% | Added |
| Swiss National Bank | 778,300 | $346.5M | 0.21% | +52,100+7.2% | Added |
| Barclays PLC | 822,937 | $366.4M | 0.15% | −2,993−0.4% | Reduced |
| Renaissance Technologies LLC | 1,004,888 | $447.4M | 0.60% | −166,683−14.2% | Reduced |
| Nuveen, LLC | 1,062,235 | $472.9M | 0.13% | +63,817+6.4% | Added |
| WCM Investment Management, LLC | 1,163,670 | $513.5M | 1.17% | +64,730+5.9% | Added |
| Amundi | 1,133,226 | $517.9M | 0.18% | −1,965,643−63.4% | Reduced |
| DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main | 1,205,796 | $536.8M | 0.56% | +244,942+25.5% | Added |
| Massachusetts Financial Services Co | 1,284,354 | $571.8M | 0.18% | −740,554−36.6% | Reduced |
| Royal Bank of Canada | 1,384,368 | $616.3M | 0.12% | +175,700+14.5% | Added |
| Deutsche Bank AG | 1,407,634 | $626.7M | 0.23% | +60,748+4.5% | Added |
| Clearbridge Investments, LLC | 1,527,864 | $680.2M | 0.55% | −151,307−9.0% | Reduced |
| Bank of New York Mellon Corp | 1,600,473 | $712.5M | 0.13% | −111,192−6.5% | Reduced |
| Parnassus Investments | 1,711,440 | $761.9M | 1.76% | −61,278−3.5% | Reduced |
| Charles Schwab Investment Management Inc | 1,773,625 | $789.6M | 0.14% | +48,344+2.8% | Added |
| Legal & General Group Plc | 1,889,777 | $841.3M | 0.21% | −4,392−0.2% | Reduced |
| Goldman Sachs Group Inc | 1,931,760 | $860.0M | 0.14% | +197,166+11.4% | Added |
| Invesco Ltd. | 1,984,046 | $883.3M | 0.15% | +138,406+7.5% | Added |
| Victory Capital Management Inc | 2,155,164 | $967.8M | 0.62% | +1,861,279+633.3% | Added |
| Ameriprise Financial Inc | 2,181,362 | $971.1M | 0.24% | −54,107−2.4% | Reduced |
| Edgewood Management LLC | 2,454,947 | $1.09B | 3.47% | −189,079−7.2% | Reduced |
| Janus Henderson Group PLC | 2,619,534 | $1.17B | 0.57% | −128,403−4.7% | Reduced |
| Capital International Investors | 2,635,903 | $1.17B | 0.20% | +1,986,004+305.6% | Added |
| Northern Trust Corp | 2,658,581 | $1.18B | 0.16% | +39,189+1.5% | Added |
| Bank of America Corp | 2,807,617 | $1.25B | 0.10% | −57,381−2.0% | Reduced |
| UBS Asset Management Americas Inc | 3,067,473 | $1.37B | 0.28% | +507,997+19.8% | Added |
| Price T Rowe Associates Inc | 3,159,870 | $1.41B | 0.16% | +242,643+8.3% | Added |
| Morgan Stanley | 3,331,439 | $1.48B | 0.10% | −77,081−2.3% | Reduced |
| Norges Bank | 3,580,356 | $1.59B | 0.20% | +216,206+6.4% | Added |
| Loomis Sayles & Co L P | 3,813,378 | $1.70B | 2.13% | +65,047+1.7% | Added |
| Alliancebernstein L.P. | 4,378,320 | $1.95B | 0.64% | +424,808+10.7% | Added |
| Wellington Management Group LLP | 4,813,386 | $2.14B | 0.39% | −641,362−11.8% | Reduced |
| JPMorgan Chase & Co | 5,869,361 | $2.61B | 0.18% | −1,886,284−24.3% | Reduced |
| Geode Capital Management, LLC | 5,928,747 | $2.63B | 0.18% | +166,987+2.9% | Added |
| Jennison Associates LLC | 6,151,505 | $2.74B | 1.62% | +1,089,063+21.5% | Added |
| FMR LLC | 6,406,372 | $2.85B | 0.16% | −1,320,812−17.1% | Reduced |
| State Street Corp | 11,775,227 | $5.24B | 0.20% | −13,430−0.1% | Reduced |
| Capital Research Global Investors | 16,108,291 | $7.17B | 1.44% | +1,571,947+10.8% | Added |
| BlackRock, Inc. | 21,871,945 | $9.74B | 0.19% | +89,012+0.4% | Added |
| Vanguard Group Inc | 23,973,777 | $10.7B | 0.17% | +482,616+2.1% | Added |
| Capital World Investors | 28,732,143 | $12.8B | 1.86% | +198,835+0.7% | Added |
| Millennium Management LLC | 0 | $0 | 0.00% | −309,935−100.0% | Sold out |
| PFM Health Sciences, LP | 0 | $0 | 0.00% | −126,989−100.0% | Sold out |
| Employees Retirement System of Texas | 0 | $0 | 0.00% | −120,200−100.0% | Sold out |
| Corebridge Financial, Inc. | 0 | $0 | 0.00% | −84,328−100.0% | Sold out |
| GuoLine Advisory Pte Ltd | 0 | $0 | 0.00% | −79,700−100.0% | Sold out |
| Armistice Capital, LLC | 0 | $0 | 0.00% | −50,000−100.0% | Sold out |
| Braun Stacey Associates Inc | 0 | $0 | 0.00% | −44,672−100.0% | Sold out |
| Virginia Retirement Systems Et Al | 0 | $0 | 0.00% | −43,500−100.0% | Sold out |
| Telemark Asset Management, LLC | 0 | $0 | 0.00% | −40,000−100.0% | Sold out |
| Factory Mutual Insurance Co | 0 | $0 | 0.00% | −29,900−100.0% | Sold out |
| Alaska Permanent Fund Corp | 0 | $0 | 0.00% | −26,346−100.0% | Sold out |
| SIH Partners, LLLP | 0 | $0 | 0.00% | −25,388−100.0% | Sold out |
| Walleye Trading LLC | 0 | $0 | 0.00% | −22,021−100.0% | Sold out |
| Polar Asset Management Partners Inc. | 0 | $0 | 0.00% | −21,594−100.0% | Sold out |
| Susquehanna Fundamental Investments, LLC | 0 | $0 | 0.00% | −19,986−100.0% | Sold out |
| Lombard Odier Asset Management (Europe) Ltd | 0 | $0 | 0.00% | −19,930−100.0% | Sold out |
| Longbow Finance SA | 0 | $0 | 0.00% | −18,686−100.0% | Sold out |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −15,008−100.0% | Sold out |
| Quantitative Investment Management, LLC | 0 | $0 | 0.00% | −14,997−100.0% | Sold out |
| Cinctive Capital Management LP | 0 | $0 | 0.00% | −13,891−100.0% | Sold out |
| Alberta Investment Management Corp | 0 | $0 | 0.00% | −12,686−100.0% | Sold out |
| SummitTX Capital, L.P. | 0 | $0 | 0.00% | −11,743−100.0% | Sold out |
| Virtu Financial LLC | 0 | $0 | 0.00% | −9,064−100.0% | Sold out |
| Twin Tree Management, LP | 0 | $0 | 0.00% | −8,773−100.0% | Sold out |
| Cutter & CO Brokerage, Inc. | 0 | $0 | 0.00% | −8,407−100.0% | Sold out |
| Allstate Corp | 0 | $0 | 0.00% | −7,487−100.0% | Sold out |
| Fiera Capital Corp | 0 | $0 | 0.00% | −7,092−100.0% | Sold out |
| Wahed Invest LLC | 0 | $0 | 0.00% | −6,663−100.0% | Sold out |
| Chase Investment Counsel Corp | 0 | $0 | 0.00% | −6,596−100.0% | Sold out |
| Triasima Portfolio Management inc. | 0 | $0 | 0.00% | −6,213−100.0% | Sold out |
| United Services Automobile Association | 0 | $0 | 0.00% | −5,953−100.0% | Sold out |
| LMR Partners LLP | 0 | $0 | 0.00% | −5,889−100.0% | Sold out |
| Prelude Capital Management, LLC | 0 | $0 | 0.00% | −5,632−100.0% | Sold out |
| Andra AP-fonden | 0 | $0 | 0.00% | −5,500−100.0% | Sold out |
| Element Capital Management LLC | 0 | $0 | 0.00% | −5,448−100.0% | Sold out |
| Two Sigma Investments, LP | 0 | $0 | 0.00% | −4,121−100.0% | Sold out |
| Camarda Financial Advisors, LLC | 0 | $0 | 0.00% | −3,597−100.0% | Sold out |