Skip to main content

Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
−28 vs. Q1 2025
Shares held
240.9M
+1.26M (+0.5%) vs. Q1 2025
Total value
$107.2B
−$8.95B (−7.7%) vs. Q1 2025
New holders
121
618 more added
Sold out
149
608 more reduced

26 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ2 2025: $107.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2025.

Institutions holding VRTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Police & Firemen's Retirement System of New Jersey39,035$17.4M0.16%+1,393+3.7%Added
Burney Co39,131$17.4M0.59%+326+0.8%Added
La Banque Postale Asset Management SA39,341$17.5M0.25%−14,200−26.5%Reduced
Pacer Advisors, Inc.39,958$17.8M0.04%+9,262+30.2%Added
Martingale Asset Management L P41,282$18.4M0.45%−565−1.4%Reduced
Steward Partners Investment Advisory, LLC41,551$18.5M0.14%+518+1.3%Added
Segall Bryant & Hamill, LLC42,328$18.8M0.26%−10,494−19.9%Reduced
Utah Retirement Systems42,533$18.9M0.20%−270−0.6%Reduced
W.G. Shaheen & Associates DBA Whitney & Co43,809$19.5M1.92%+140.0%Added
Wealthfront Advisers LLC43,918$19.6M0.05%−3,014−6.4%Reduced
USS Investment Management Ltd44,154$19.7M0.12%−237−0.5%Reduced
China Universal Asset Management Co., Ltd.44,265$19.7M1.85%−4,601−9.4%Reduced
AIA Group Ltd44,484$19.8M0.43%+10,255+30.0%Added
Ilmarinen Mutual Pension Insurance Co44,800$19.9M0.16%+11,500+34.5%Added
State of Alaska, Department of Revenue45,255$20.1M0.22%−1,250−2.7%Reduced
Aristotle Atlantic Partners, LLC45,376$20.2M0.61%−2,610−5.4%Reduced
Calamos Advisors LLC45,753$20.4M0.09%00.0%Unchanged
Lido Advisors, LLC45,822$20.4M0.11%+11,590+33.9%Added
C WorldWide Group Holding A/S46,057$20.5M0.28%−8,000−14.8%Reduced
Boston Common Asset Management, LLC46,063$20.5M0.57%−4,900−9.6%Reduced
Smith Group Asset Management, LLC46,255$20.6M1.35%+612+1.3%Added
Quantinno Capital Management LP46,322$20.6M0.09%+7,897+20.6%Added
Cumberland Partners Ltd46,570$20.7M1.44%−177−0.4%Reduced
Sanctuary Advisors, LLC47,170$21.0M0.13%+1,303+2.8%Added
Sumitomo Mitsui DS Asset Management Company, Ltd48,090$21.4M0.19%+1,726+3.7%Added
Hallmark Capital Management Inc48,689$21.7M1.56%−795−1.6%Reduced
De Burlo Group Inc48,765$21.7M2.86%+30+0.1%Added
Bank of Nova Scotia49,609$22.1M0.05%+21,921+79.2%Added
Harvest Fund Management Co., Ltd49,515$22.1M1.04%+14,580+41.7%Added
Hudson Bay Capital Management LP50,246$22.4M0.15%+405+0.8%Added
IFM Investors Pty Ltd50,317$22.4M0.21%+1,781+3.7%Added
CIBC World Markets Corp50,606$22.5M0.15%+19,599+63.2%Added
Jacobs Levy Equity Management, Inc50,956$22.7M0.09%−15,278−23.1%Reduced
AustralianSuper Pty Ltd51,256$22.8M0.12%−76,687−59.9%Reduced
Advisor Group Holdings, Inc.50,328$22.9M0.04%+16,779+50.0%Added
Forsta Ap-Fonden52,000$23.2M0.15%−6,200−10.7%Reduced
Cullinan Associates Inc52,012$23.2M1.53%−1,100−2.1%Reduced
Barlow Wealth Partners, Inc.50,958$23.3M2.79%+865+1.7%Added
Zurich Insurance Group Ltd52,372$23.3M0.18%−157,534−75.0%Reduced
Shelton Capital Management53,015$23.6M0.54%−336−0.6%Reduced
Illinois Municipal Retirement Fund53,624$23.9M0.32%+3,034+6.0%Added
Motley Fool Wealth Management, LLC53,913$24.0M1.45%+20,864+63.1%Added
MEAG MUNICH ERGO, Kapitalanlagegesellschaft mbH54,104$24.1M0.68%+54,104New
Reynders McVeigh Capital Management, LLC54,310$24.2M1.21%+974+1.8%Added
Zacks Investment Management54,316$24.2M0.21%−31,734−36.9%Reduced
Retirement Systems of Alabama55,102$24.5M0.09%−80−0.1%Reduced
Atwood & Palmer Inc55,192$24.6M1.54%+208+0.4%Added
Hemenway Trust Co LLC55,515$24.7M1.91%+1,191+2.2%Added
Amalgamated Bank55,735$24.8M0.19%+2,005+3.7%Added
Edgemoor Investment Advisors, Inc.56,024$24.9M2.15%−772−1.4%Reduced
HighTower Advisors, LLC56,347$25.1M0.03%+2,722+5.1%Added
Swiss Life Asset Management Ltd57,900$25.8M0.15%+28,296+95.6%Added
Moody Lynn & Lieberson, LLC58,077$25.9M1.49%+822+1.4%Added
Commonwealth Equity Services, LLC59,398$26.4M0.03%−6,346−9.7%Reduced
Cetera Investment Advisers60,196$26.8M0.05%−4,578−7.1%Reduced
Groupama Asset Managment61,297$27.1M0.45%+9,364+18.0%Added
Foster Dykema Cabot & Partners, LLC60,923$27.1M1.91%−532−0.9%Reduced
Epoch Investment Partners, Inc.61,026$27.2M0.14%−20,810−25.4%Reduced
Rhenman & Partners Asset Management AB61,455$27.4M3.46%−5,295−7.9%Reduced
Arrowstreet Capital, Limited Partnership61,470$27.4M0.02%+61,470New
Trillium Asset Management, LLC61,474$27.4M0.74%+5,658+10.1%Added
Susquehanna International Group, LLP62,209$27.7M0.04%+21,088+51.3%Added
GF Fund Management Co. Ltd.62,317$27.7M0.56%+1,505+2.5%Added
Xponance, Inc.62,600$27.9M0.23%+13,431+27.3%Added
Czech National Bank62,770$27.9M0.22%+3,790+6.4%Added
Commonwealth of Pennsylvania Public School Empls Retrmt Sys62,981$28.0M0.15%+4,256+7.2%Added
Davidson Investment Advisors63,689$28.4M1.27%+806+1.3%Added
Caisse de Depot Et Placement du Quebec64,396$28.7M0.06%−60,451−48.4%Reduced
Comerica Bank64,675$28.8M0.11%−746−1.1%Reduced
AMF Pensionsforsakring AB64,705$28.8M0.19%+3,710+6.1%Added
Alyeska Investment Group, L.P.65,000$28.9M0.10%−366,804−84.9%Reduced
Nisa Investment Advisors, LLC65,417$29.1M0.13%−2,883−4.2%Reduced
Nissay Asset Management Corp65,638$29.2M0.17%+1,828+2.9%Added
Gateway Investment Advisers LLC65,794$29.3M0.32%−59−0.1%Reduced
Teachers Retirement System of the State of Kentucky68,180$30.4M0.25%+5,185+8.2%Added
Banco Santander, S.A.70,188$31.2M0.30%+6,160+9.6%Added
Capitolis Liquid Global Markets LLC71,000$31.6M0.23%+71,000New
Vontobel Holding Ltd.71,798$32.0M0.11%−3,008−4.0%Reduced
Janney Montgomery Scott LLC71,890$32.0M0.08%+3,271+4.8%Added
State of Michigan Retirement System72,523$32.3M0.17%+400+0.6%Added
Erste Asset Management GmbH73,903$32.6M0.27%+5,133+7.5%Added
Arizona State Retirement System75,094$33.4M0.19%−443−0.6%Reduced
Rafferty Asset Management, LLC75,108$33.4M0.11%+4,278+6.0%Added
Daiwa Securities Group Inc.75,832$33.8M0.12%+4,600+6.5%Added
The PNC Financial Services Group, Inc.76,156$33.9M0.02%−2,005−2.6%Reduced
NEOS Investment Management LLC76,237$33.9M0.42%+24,915+48.5%Added
Beacon Investment Advisory Services, Inc.77,031$34.3M1.51%−870−1.1%Reduced
MetLife Investment Management77,148$34.3M0.20%+4,787+6.6%Added
CIBC Asset Management Inc80,986$36.1M0.11%−4,393−5.1%Reduced
Wealth Enhancement Advisory Services, LLC82,641$38.0M0.06%+2,452+3.1%Added
State of New Jersey Common Pension Fund D86,729$38.6M0.15%00.0%Unchanged
DnB Asset Management AS86,931$38.7M0.16%−89,600−50.8%Reduced
Creative Planning87,174$38.8M0.03%−1,666−1.9%Reduced
Polar Capital Holdings Plc87,500$39.0M0.20%−37,500−30.0%Reduced
Thrivent Financial for Lutherans88,202$39.3M0.09%+1,119+1.3%Added
Country Trust Bank90,136$40.1M0.90%+312+0.3%Added
Fjarde Ap-Fonden /Fourth Swedish National Pension Fund91,088$40.6M0.37%+17,200+23.3%Added
Woodline Partners LP91,664$40.8M0.22%−61,496−40.2%Reduced
Assetmark, Inc92,391$41.1M0.10%+7,094+8.3%Added
KLP Kapitalforvaltning AS92,841$41.3M0.18%+5,100+5.8%Added