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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
−28 vs. Q1 2025
Shares held
240.9M
+1.26M (+0.5%) vs. Q1 2025
Total value
$107.2B
−$8.95B (−7.7%) vs. Q1 2025
New holders
121
618 more added
Sold out
149
608 more reduced

26 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ2 2025: $107.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2025.

Institutions holding VRTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Morse Asset Management, Inc10,287$4.58M1.00%−174−1.7%Reduced
Greenwood Capital Associates LLC10,298$4.58M0.57%−1,595−13.4%Reduced
Fayez Sarofim & Co10,358$4.61M0.01%−34−0.3%Reduced
Parsons Capital Management Inc10,428$4.64M0.29%+2,660+34.2%Added
Generali Investments CEE, investicni spolecnost, a.s.10,491$4.67M0.38%−539−4.9%Reduced
E. Ohman J:or Asset Management AB10,520$4.68M0.12%−970−8.4%Reduced
Banque Cantonale Vaudoise10,529$4.69M0.19%+231+2.2%Added
GAM Holding AG10,553$4.70M0.33%−492−4.5%Reduced
HB Wealth Management, LLC10,583$4.71M0.04%−73−0.7%Reduced
Thematics Asset Management10,598$4.72M0.21%+2,642+33.2%Added
Keybank National Association10,678$4.75M0.02%−1,523−12.5%Reduced
Mark Sheptoff Financial Planning, LLC10,771$4.80M2.56%+100+0.9%Added
Lockheed Martin Investment Management Co10,860$4.83M0.18%+2,760+34.1%Added
Siemens Fonds Invest GmbH10,915$4.86M0.29%+307+2.9%Added
EP Wealth Advisors, LLC10,930$4.87M0.03%+5,481+100.6%Added
Spire Wealth Management11,298$4.91M0.18%−7,278−39.2%Reduced
Northwest Bancshares, Inc.11,203$4.99M0.87%−216−1.9%Reduced
EFG Asset Management (North America) Corp.11,204$4.99M0.70%+2,072+22.7%Added
Diversify Wealth Management, LLC12,988$5.04M0.31%+1,976+17.9%Added
Brinker Capital Investments, LLC11,341$5.05M0.04%+1,768+18.5%Added
First American Trust, FSB11,348$5.05M0.40%−5,663−33.3%Reduced
Ethic Inc.11,495$5.07M0.09%+58+0.5%Added
Northwestern Mutual Wealth Management Co11,532$5.13M0.00%−1,505−11.5%Reduced
Investment Management Corp of Ontario11,675$5.20M0.08%−3,092−20.9%Reduced
Codex Capital Asset Management L.L.C.11,750$5.23M2.09%00.0%Unchanged
Slow Capital, Inc.11,814$5.26M0.64%−20−0.2%Reduced
Traynor Capital Management, Inc.11,675$5.28M0.37%+631+5.7%Added
BTC Capital Management, Inc.11,928$5.31M0.43%+589+5.2%Added
GWM Advisors LLC11,929$5.31M0.03%+986+9.0%Added
New Mexico Educational Retirement Board12,000$5.34M0.17%00.0%Unchanged
Kayne Anderson Rudnick Investment Management LLC12,013$5.35M0.01%−221−1.8%Reduced
Kidder Stephen W12,130$5.40M1.62%+164+1.4%Added
Covenant Asset Management, LLC12,155$5.41M1.11%−387−3.1%Reduced
Cresset Asset Management, LLC12,227$5.44M0.03%−2,100−14.7%Reduced
Americana Partners, LLC12,334$5.49M0.19%+97+0.8%Added
Oddo BHF Asset Management SAS12,388$5.52M0.21%−4,309−25.8%Reduced
Maryland State Retirement & Pension System12,500$5.57M0.12%+409+3.4%Added
Compagnie Lombard Odier SCmA12,565$5.59M0.07%00.0%Unchanged
Forte Capital LLC12,587$5.60M0.60%+135+1.1%Added
Avantax Advisory Services, Inc.12,873$5.73M0.03%+199+1.6%Added
Chicago Capital, LLC12,875$5.73M0.14%+469+3.8%Added
Fisher Funds Management LTD12,898$5.74M0.14%−1,433−10.0%Reduced
United Capital Financial Advisers, LLC13,122$5.84M0.05%+1,156+9.7%Added
Ci Investments Inc.13,128$5.84M0.02%−17,886−57.7%Reduced
Gulf International Bank (UK) Ltd13,134$5.85M0.21%−1,774−11.9%Reduced
Jump Financial, LLC13,292$5.92M0.07%+12,084+1,000.3%Added
Captrust Financial Advisors13,312$5.93M0.01%−218−1.6%Reduced
Securian Asset Management, Inc13,442$5.98M0.17%−156−1.1%Reduced
PKO Investment Management Joint-Stock Co13,500$6.01M0.65%+11,700+650.0%Added
BI Asset Management Fondsmaeglerselskab A/S13,677$6.09M0.06%+1,949+16.6%Added
Omers Administration Corp13,754$6.12M0.05%+100+0.7%Added
Channel Wealth LLC13,877$6.18M1.75%+11,833+578.9%Added
Aptus Capital Advisors, LLC13,887$6.18M0.06%−10,353−42.7%Reduced
Bleakley Financial Group, LLC13,931$6.20M0.16%+2,609+23.0%Added
Knuff & Co LLC13,996$6.23M1.96%+171+1.2%Added
Metis Global Partners, LLC14,118$6.29M0.16%−1,581−10.1%Reduced
Madison Asset Management, LLC14,192$6.32M0.07%−204−1.4%Reduced
Toroso Investments, LLC14,265$6.35M0.04%−126−0.9%Reduced
TD Waterhouse Canada Inc.14,102$6.37M0.05%+4,479+46.5%Added
Kestra Advisory Services, LLC14,358$6.39M0.03%+1,148+8.7%Added
Sequoia Financial Advisors, LLC14,373$6.40M0.04%+442+3.2%Added
Princeton Capital Management LLC14,475$6.44M1.91%−561−3.7%Reduced
Baldwin Investment Management, LLC14,541$6.47M0.78%+711+5.1%Added
Ameritas Investment Partners, Inc.14,909$6.64M0.21%−1,110−6.9%Reduced
Princeton Global Asset Management LLC15,025$6.69M1.21%−186−1.2%Reduced
Northwest & Ethical Investments L.P.15,089$6.72M0.17%+530+3.6%Added
Puzo Michael J15,340$6.83M1.95%+55+0.4%Added
Trifecta Capital Advisors, LLC15,340$6.83M1.14%+802+5.5%Added
Park Avenue Securities LLC15,362$6.84M0.06%+23+0.1%Added
Hartford Investment Management Co15,498$6.90M0.22%−172−1.1%Reduced
South Dakota Investment Council15,623$6.96M0.13%−10,780−40.8%Reduced
New Age Alpha Advisors, LLC15,700$6.99M0.31%+2,563+19.5%Added
Motley Fool Asset Management LLC15,794$7.03M0.32%+1,875+13.5%Added
Fulcrum Capital LLC15,798$7.03M1.49%+220+1.4%Added
Nia Impact Advisors, LLC15,887$7.07M2.44%−45−0.3%Reduced
NBW Capital LLC15,939$7.10M1.53%+293+1.9%Added
Beacon Pointe Advisors, LLC16,029$7.14M0.07%−196−1.2%Reduced
Ieq Capital, LLC16,219$7.22M0.04%−5,786−26.3%Reduced
Janney Capital Management LLC16,231$7.23M0.47%−276−1.7%Reduced
Gabelli Funds LLC16,329$7.27M0.05%−21−0.1%Reduced
Baird Financial Group, Inc.16,392$7.30M0.01%+391+2.4%Added
Kentucky Retirement Systems16,574$7.38M0.22%−1,085−6.1%Reduced
Generali Asset Management SPA SGR16,627$7.40M0.17%−1,705−9.3%Reduced
UniSuper Management Pty Ltd16,648$7.41M0.05%−189−1.1%Reduced
Callan Family Office, LLC16,715$7.44M0.23%+11,198+203.0%Added
Torray LLC16,879$7.51M1.09%+1,158+7.4%Added
Agf Management Ltd16,885$7.52M0.03%+5,402+47.0%Added
Banque Pictet & Cie SA16,937$7.54M0.08%+5,564+48.9%Added
Silvercrest Asset Management Group LLC16,953$7.55M0.05%+107+0.6%Added
Shell Asset Management Co17,181$7.65M0.26%+3,809+28.5%Added
Envestnet Portfolio Solutions, Inc.17,294$7.70M0.03%+272+1.6%Added
Cambridge Investment Research Advisors, Inc.17,329$7.71M0.02%+998+6.1%Added
Wolverine Trading, LLC17,595$7.76M0.20%+16,180+1,143.5%Added
Intech Investment Management LLC17,488$7.79M0.07%+8,791+101.1%Added
Fiduciary Trust Co17,519$7.80M0.10%+255+1.5%Added
Broderick Brian C17,671$7.87M1.56%−330−1.8%Reduced
M&T Bank Corp17,683$7.87M0.03%−681−3.7%Reduced
Mizuho Securities USA LLC17,750$7.90M0.17%+17,750New
Quadrature Capital Ltd17,913$7.97M0.14%+17,913New
Grandfield & Dodd, LLC18,287$8.14M0.48%+141+0.8%Added