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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
−28 vs. Q1 2025
Shares held
240.9M
+1.26M (+0.5%) vs. Q1 2025
Total value
$107.2B
−$8.95B (−7.7%) vs. Q1 2025
New holders
121
618 more added
Sold out
149
608 more reduced

26 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ2 2025: $107.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2025.

Institutions holding VRTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Stonegate Investment Group, LLC6,142$2.73M0.07%−214−3.4%Reduced
Fred Alger Management, LLC6,173$2.75M0.01%−7,151−53.7%Reduced
Meeder Advisory Services, Inc.6,176$2.75M0.14%−184−2.9%Reduced
Crossmark Global Holdings, Inc.6,221$2.77M0.04%+47+0.8%Added
Merit Financial Group, LLC6,260$2.79M0.03%+833+15.3%Added
CWA Asset Management Group, LLC6,274$2.79M0.12%+69+1.1%Added
Advisory Services Network, LLC6,122$2.80M0.05%+409+7.2%Added
Diversify Advisory Services, LLC7,291$2.83M0.11%+1,518+26.3%Added
RSM US Wealth Management LLC6,353$2.83M0.04%−40−0.6%Reduced
Griffin Asset Management, Inc.6,408$2.85M0.34%−1,609−20.1%Reduced
Edgestream Partners, L.P.6,415$2.86M0.08%+5,677+769.2%Added
NewEdge Wealth, LLC7,618$2.86M0.04%−1,690−18.2%Reduced
BLI - Banque de Luxembourg Investments6,500$2.87M0.08%+6,500New
Draper Asset Management, LLC6,500$2.87M1.89%+69+1.1%Added
Scotia Capital Inc.6,484$2.89M0.01%+412+6.8%Added
Condor Capital Management6,502$2.89M0.25%−26−0.4%Reduced
Nikko Asset Management Americas, Inc.6,527$2.90M0.03%−145−2.2%Reduced
Harbour Capital Advisors, LLC6,367$2.91M0.61%+145+2.3%Added
Principal Securities, Inc.6,600$2.94M0.06%+1,137+20.8%Added
Wedbush Securities Inc6,622$2.95M0.10%+19+0.3%Added
Coppell Advisory Solutions LLC6,686$2.95M0.36%+2,846+74.1%Added
Marex Group plc6,703$2.98M0.06%+6,703New
Hennion & Walsh Asset Management, Inc.6,756$3.01M0.12%−39−0.6%Reduced
Graphene Investments SAS6,800$3.03M1.97%+1,300+23.6%Added
Brown Advisory Inc6,858$3.05M0.00%+277+4.2%Added
Thompson Siegel & Walmsley LLC6,870$3.06M0.05%−239−3.4%Reduced
Vision Capital Management, Inc.6,872$3.06M0.40%+307+4.7%Added
North Star Asset Management Inc6,883$3.06M0.13%+864+14.4%Added
Kinneret Advisory, LLC6,895$3.07M0.28%−10−0.1%Reduced
CWM, LLC6,908$3.08M0.01%−776−10.1%Reduced
Sectoral Asset Management Inc6,945$3.09M2.04%+2,220+47.0%Added
CIBC Private Wealth Group, LLC7,029$3.13M0.01%+467+7.1%Added
Kentucky Retirement Systems Insurance Trust Fund7,034$3.13M0.22%−488−6.5%Reduced
Glenview Trust Co7,076$3.15M0.05%+156+2.3%Added
Dempze Nancy E7,180$3.20M1.84%+117+1.7%Added
Private Advisor Group, LLC7,204$3.21M0.02%−248−3.3%Reduced
Davidson Capital Management Inc.7,224$3.22M0.77%−196−2.6%Reduced
Sumitomo Life Insurance Co7,236$3.22M0.22%−301−4.0%Reduced
GLOBALT Investments LLC7,285$3.24M0.12%−410−5.3%Reduced
First National Bank of Mount Dora, Trust Investment Services7,291$3.25M0.73%−58−0.8%Reduced
Sand Hill Global Advisors, LLC7,320$3.26M0.12%+395+5.7%Added
Delaney Dennis R7,343$3.27M1.68%+440+6.4%Added
Notis-McConarty Edward7,381$3.29M1.60%+106+1.5%Added
Cavalier Investments, LLC7,435$3.31M1.00%−138−1.8%Reduced
Level Four Advisory Services, LLC7,451$3.32M0.12%−985−11.7%Reduced
Bessemer Group Inc7,465$3.32M0.01%−19−0.3%Reduced
Commerce Bank7,490$3.33M0.02%−853−10.2%Reduced
Boston Private Wealth LLC7,507$3.34M0.18%−3,129−29.4%Reduced
Paradigm Financial Partners, LLC7,562$3.37M0.37%−402−5.0%Reduced
Associated Banc-Corp7,583$3.38M0.10%−580−7.1%Reduced
EagleClaw Capital Managment, LLC7,585$3.38M0.50%−10−0.1%Reduced
Transamerica Financial Advisors, Inc.7,631$3.40M0.32%−220−2.8%Reduced
Ashford Capital Management Inc7,707$3.43M0.40%−485−5.9%Reduced
Duncker Streett & Co Inc7,732$3.44M0.63%−15−0.2%Reduced
Johnson Investment Counsel Inc7,748$3.45M0.03%−171−2.2%Reduced
Richard Bernstein Advisors LLC7,751$3.45M0.09%−855−9.9%Reduced
Joseph Group Capital Management7,760$3.45M1.16%+634+8.9%Added
Horizon Investments, LLC7,842$3.49M0.06%+2,793+55.3%Added
J.P. Marvel Investment Advisors, LLC7,855$3.50M0.56%−137−1.7%Reduced
Groupe la Francaise7,989$3.54M0.06%+1,625+25.5%Added
Baldwin Brothers Inc7,994$3.56M0.24%−125−1.5%Reduced
Andrew Hill Investment Advisors, Inc.8,003$3.56M2.87%+1,430+21.8%Added
Miracle Mile Advisors, LLC8,035$3.58M0.06%+1,467+22.3%Added
Federation des caisses Desjardins du Quebec8,038$3.58M0.02%−11,336−58.5%Reduced
Tema ETFs LLC8,068$3.59M0.95%−380−4.5%Reduced
Leavell Investment Management, Inc.8,089$3.60M0.16%+355+4.6%Added
Peloton Wealth Strategists8,150$3.63M1.46%+196+2.5%Added
Linden Thomas Advisory Services, LLC8,161$3.63M0.40%+428+5.5%Added
Northwestern Mutual Investment Management Company, LLC8,193$3.65M0.06%+26+0.3%Added
Bokf, NA8,254$3.67M0.06%+1,154+16.3%Added
Sepio Capital, LP8,347$3.72M0.26%−13−0.2%Reduced
Privium Fund Management B.V.8,300$3.75M0.81%00.0%Unchanged
Ascent Group, LLC8,652$3.85M0.15%−790−8.4%Reduced
Tokio Marine Asset Management Co Ltd8,741$3.89M0.15%+536+6.5%Added
Vestmark Advisory Solutions, Inc.8,763$3.90M0.06%−3,625−29.3%Reduced
Hedeker Wealth, LLC8,791$3.91M0.91%−216−2.4%Reduced
Bensler, LLC8,795$3.92M0.44%−40−0.5%Reduced
Howard Capital Management Inc.8,918$3.97M0.06%+2,282+34.4%Added
Atlantic Union Bankshares Corp8,947$3.98M0.09%+7,876+735.4%Added
Bamco Inc9,000$4.01M0.01%−3,000−25.0%Reduced
Empirical Finance, LLC9,006$4.01M0.21%+60+0.7%Added
Central Trust Co9,016$4.01M0.09%+31+0.3%Added
Bulltick Wealth Management, LLC9,095$4.05M1.00%+6+0.1%Added
Sigma Investment Counselors Inc9,299$4.14M0.23%+548+6.3%Added
Howe & Rusling Inc9,444$4.20M0.31%+318+3.5%Added
Hamilton Capital Partners Inc.9,516$4.24M0.22%+1,742+22.4%Added
Pinnacle Financial Partners Inc9,617$4.28M0.09%+263+2.8%Added
E Fund Management Co., Ltd.9,628$4.29M0.20%−256−2.6%Reduced
Meiji Yasuda Asset Management Co Ltd.9,633$4.29M0.21%−3,013−23.8%Reduced
Benjamin Edwards Inc9,634$4.29M0.05%+1,428+17.4%Added
Baker Chad R9,740$4.34M0.81%00.0%Unchanged
Synovus Financial Corp9,777$4.35M0.05%+1,271+14.9%Added
AG2R la Mondiale Gestion D'Actifs9,788$4.36M0.22%+187+1.9%Added
Empowered Funds, LLC9,822$4.37M0.05%+4,632+89.2%Added
Commerzbank Aktiengesellschaft9,850$4.39M0.10%+8,069+453.1%Added
Tang Capital Management LLC10,000$4.45M0.23%+10,000New
Diadema Partners LP10,000$4.45M2.77%+10,000New
Crestwood Advisors Group LLC10,043$4.47M0.08%−232−2.3%Reduced
Prospera Financial Services Inc10,235$4.56M0.08%+7,204+237.7%Added
Vinva Investment Management Ltd10,345$4.57M0.12%−2,792−21.3%Reduced