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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 2 sales; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
−28 vs. Q1 2025
Shares held
240.9M
+1.26M (+0.5%) vs. Q1 2025
Total value
$107.2B
−$8.95B (−7.7%) vs. Q1 2025
New holders
121
618 more added
Sold out
149
608 more reduced

26 institutions that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ2 2025: $107.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q1 2025.

Institutions holding VRTX in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Eqis Capital Management, Inc.4,110$1.83M0.15%−519−11.2%Reduced
Avestar Capital, LLC4,111$1.83M0.13%+253+6.6%Added
TD Private Client Wealth LLC4,118$1.83M0.05%−2,107−33.8%Reduced
Moors & Cabot, Inc.4,134$1.84M0.09%−1,363−24.8%Reduced
National Asset Management, Inc.4,141$1.84M0.09%−1,173−22.1%Reduced
Hilltop Holdings Inc.4,177$1.86M0.12%+542+14.9%Added
Waldron Private Wealth LLC4,181$1.86M0.08%−15−0.4%Reduced
United Asset Strategies, Inc.4,187$1.86M0.16%−425−9.2%Reduced
Nations Financial Group Inc,4,216$1.88M0.13%+174+4.3%Added
Signature Wealth Management Group4,244$1.89M0.75%+26+0.6%Added
Vise Technologies, Inc.4,278$1.90M0.08%+4,278New
Choate Investment Advisors4,302$1.92M0.04%−183−4.1%Reduced
Lipe & Dalton4,306$1.92M1.04%−275−6.0%Reduced
Mather Group, LLC.4,316$1.92M0.02%+170+4.1%Added
Integrated Wealth Concepts LLC4,330$1.93M0.02%−384−8.1%Reduced
Harrell Investment Partners, LLC4,352$1.94M0.49%+4,352New
Genus Capital Management Inc.4,370$1.95M0.25%−410−8.6%Reduced
Oarsman Capital, Inc.4,387$1.95M0.31%+45+1.0%Added
Artia Global Partners LP4,400$1.96M0.50%+4,400New
Procyon Private Wealth Partners, LLC4,428$1.97M0.19%−14,170−76.2%Reduced
Philip James Wealth Mangement, LLC4,458$1.98M0.25%+1,467+49.0%Added
MRP Capital Investments, LLC4,475$1.99M1.37%+395+9.7%Added
XTX Topco Ltd4,525$2.01M0.08%+4,525New
Leonteq Securities AG4,555$2.03M0.12%−1,265−21.7%Reduced
Brighton Jones LLC4,559$2.03M0.05%−1,862−29.0%Reduced
Valeo Financial Advisors, LLC4,571$2.04M0.05%−167−3.5%Reduced
Strategic Advisors LLC4,582$2.04M0.40%+20.0%Added
Ossiam4,600$2.05M0.02%−66,608−93.5%Reduced
Impax Asset Management Group plc4,622$2.06M0.01%−2,377−34.0%Reduced
SFMG, LLC4,633$2.06M0.15%−2,905−38.5%Reduced
Decatur Capital Management, Inc.4,638$2.06M0.90%00.0%Unchanged
Fidelis Capital Partners, LLC5,355$2.07M0.19%−249−4.4%Reduced
Glenmede Investment Management, LP4,672$2.08M0.01%+4,672New
GAMMA Investing LLC4,712$2.10M0.13%−290−5.8%Reduced
Oak Associates, Ltd4,771$2.12M0.14%00.0%Unchanged
Private Harbour Investment Management & Counsel, LLC4,780$2.13M2.20%−45−0.9%Reduced
RDA Financial Network4,851$2.16M0.58%−207−4.1%Reduced
D.A. Davidson & Co.4,856$2.16M0.02%+51+1.1%Added
3Chopt Investment Partners, LLC4,912$2.19M0.53%−367−7.0%Reduced
Bangor Savings Bank4,929$2.19M0.20%−406−7.6%Reduced
Trustmark National Bank Trust Department4,940$2.20M0.15%+372+8.1%Added
TFR Capital, LLC.4,950$2.20M0.80%+194+4.1%Added
Knollwood Investment Advisory, LLC4,988$2.22M0.21%00.0%Unchanged
Strategic Wealth Partners, Ltd.5,020$2.23M0.18%+5,020New
AlphaCore Capital LLC5,031$2.24M0.09%+4,052+413.9%Added
Change Path, LLC5,033$2.24M0.06%−950−15.9%Reduced
Greenleaf Trust5,037$2.24M0.02%−729−12.6%Reduced
Meiji Yasuda Life Insurance Co5,055$2.25M0.07%−20,127−79.9%Reduced
Everence Capital Management Inc5,064$2.25M0.15%00.0%Unchanged
RMR Wealth Builders5,100$2.27M0.21%+265+5.5%Added
Quadrant Capital Group LLC5,105$2.27M0.08%−233−4.4%Reduced
McGuire Investment Group, LLC5,114$2.28M0.29%−717−12.3%Reduced
Two Sigma Securities, LLC5,141$2.29M0.28%+3,848+297.6%Added
Tower View Investment Management & Research LLC5,193$2.31M1.20%+63+1.2%Added
Nwam LLC5,087$2.32M0.13%+345+7.3%Added
Boomfish Wealth Group, LLC5,243$2.33M1.35%+192+3.8%Added
MWA Asset Management5,259$2.34M1.43%+334+6.8%Added
Parallel Advisors, LLC5,266$2.34M0.05%−184−3.4%Reduced
Redhawk Wealth Advisors, Inc.5,268$2.35M0.29%+584+12.5%Added
Signaturefd, LLC5,300$2.36M0.04%−405−7.1%Reduced
Hager Investment Management Services, LLC5,345$2.38M1.42%−66−1.2%Reduced
Tiaa Trust, National Association5,403$2.41M0.01%−520−8.8%Reduced
APG Asset Management US Inc.5,334$2.41M0.02%00.0%Unchanged
Ballentine Partners, LLC5,428$2.42M0.04%−409−7.0%Reduced
Mediolanum International Funds Ltd5,494$2.42M0.03%+66+1.2%Added
Central Pacific Bank - Trust Division5,559$2.47M0.32%+134+2.5%Added
Hall Laurie J Trustee5,565$2.48M0.82%+37+0.7%Added
BNP Paribas5,576$2.48M0.08%−258−4.4%Reduced
Wimmer Associates 1, LLC5,592$2.49M1.27%−20.0%Reduced
Alpine Woods Capital Investors, LLC5,594$2.49M0.59%+9+0.2%Added
Ipswich Investment Management Co., Inc.5,608$2.50M0.60%+90+1.6%Added
Wetherby Asset Management Inc5,672$2.53M0.11%+5,672New
Qube Research & Technologies Ltd5,681$2.53M0.00%−28,865−83.6%Reduced
Wedmont Private Capital5,284$2.53M0.11%+929+21.3%Added
MUFG Securities Americas Inc.5,691$2.53M0.22%+1,146+25.2%Added
Mission Wealth Management, LP5,709$2.54M0.06%−1,202−17.4%Reduced
Freedom Day Solutions, LLC5,714$2.54M0.76%−127−2.2%Reduced
Nemes Rush Group LLC5,723$2.55M0.28%+977+20.6%Added
MASTERINVEST Kapitalanlage GmbH5,784$2.58M0.27%+5,784New
Plato Investment Management Ltd5,829$2.59M0.19%+4+0.1%Added
Little House Capital LLC5,830$2.60M0.65%−477−7.6%Reduced
Elefante Mark B5,832$2.60M1.95%+171+3.0%Added
Segment Wealth Management, LLC5,843$2.60M0.17%+151+2.7%Added
Group One Trading, L.P.5,852$2.61M0.09%+5,852New
Summit Trail Advisors, LLC5,871$2.61M0.04%+588+11.1%Added
Venturi Wealth Management, LLC5,871$2.61M0.13%−34−0.6%Reduced
Coldstream Capital Management Inc5,874$2.62M0.04%+711+13.8%Added
Illumine Investment Management, LLC5,875$2.62M2.08%+21+0.4%Added
Ostrum Asset Management5,894$2.62M0.12%−452−7.1%Reduced
Jones Financial Companies LLLP6,016$2.66M0.00%+2,035+51.1%Added
V-Square Quantitative Management LLC5,970$2.66M0.36%+1,875+45.8%Added
Univest Financial Corp5,976$2.66M0.16%+2,086+53.6%Added
Highview Capital Management LLC5,985$2.66M1.03%+68+1.1%Added
Te Ahumairangi Investment Management Ltd5,985$2.67M0.48%−3,133−34.4%Reduced
Cohen Klingenstein LLC6,000$2.67M0.09%00.0%Unchanged
Perigon Wealth Management, LLC6,004$2.67M0.06%+724+13.7%Added
Broadleaf Partners, LLC6,018$2.68M0.59%+22+0.4%Added
Northeast Financial Consultants Inc6,040$2.69M0.11%00.0%Unchanged
B&L Asset Management LLC6,073$2.70M1.55%−75−1.2%Reduced
Kestra Private Wealth Services, LLC6,127$2.73M0.04%+868+16.5%Added