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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 2 sales; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,617
+80 vs. Q4 2024
Shares held
239.9M
+4.97M (+2.1%) vs. Q4 2024
Total value
$116.3B
+$21.7B (+23.0%) vs. Q4 2024
New holders
208
638 more added
Sold out
128
576 more reduced

26 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 1,617 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ1 2025: $116.3B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2024.

Institutions holding VRTX in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Keel Point, LLC1,184$574.0K0.04%+217+22.4%Added
Avantax Planning Partners, Inc.1,194$578.9K0.02%+190+18.9%Added
Simplify Asset Management Inc.1,195$579.4K0.03%−3,494−74.5%Reduced
Founders Financial Securities LLC1,167$579.4K0.05%+20+1.7%Added
Generali Investments Towarzystwo Funduszy Inwestycyjnych1,200$581.8K0.37%00.0%Unchanged
First Commonwealth Financial Corp1,202$582.8K0.14%+677+129.0%Added
Jump Financial, LLC1,208$585.7K0.01%−1,833−60.3%Reduced
Holocene Advisors, LP1,216$589.5K0.00%−327−21.2%Reduced
Avidian Wealth Solutions, LLC1,225$593.9K0.03%+25+2.1%Added
Breed's Hill Capital LLC1,226$594.2K0.32%−10−0.8%Reduced
denkapparat Operations GmbH1,226$594.4K0.63%+234+23.6%Added
Baxter Bros Inc1,228$595.4K0.08%+206+20.2%Added
Community Bank, N.A.1,237$599.7K0.08%−23−1.8%Reduced
ICONIQ Capital, LLC1,240$601.2K0.01%+666+116.0%Added
Wright Investors Service Inc1,241$601.7K0.20%+1,241New
Sage Mountain Advisors LLC1,242$602.0K0.04%−63−4.8%Reduced
Perennial Investment Advisors, LLC1,243$602.6K0.07%+630+102.8%Added
LGT Fund Management Co Ltd.1,243$602.6K0.05%+66+5.6%Added
Bryce Point Capital, LLC1,246$602.8K0.45%−3,078−71.2%Reduced
Green Harvest Asset Management LLC1,244$603.1K0.01%+7+0.6%Added
Spinnaker Trust1,245$603.6K0.04%+10+0.8%Added
Marcum Wealth, LLC1,247$604.6K0.05%−79−6.0%Reduced
Merrion Investment Management Co, LLC1,250$606.0K0.44%+245+24.4%Added
Rathbone Brothers plc1,251$606.5K0.00%−203−14.0%Reduced
Angeles Wealth Management, LLC1,255$608.4K0.05%+208+19.9%Added
Kovack Advisors, Inc.1,256$608.9K0.06%+19+1.5%Added
Platform Technology Partners1,265$613.4K0.18%00.0%Unchanged
Alta Advisers Ltd1,271$616.2K0.26%+400+45.9%Added
Advisors Capital Management, LLC1,271$616.3K0.01%−12,975−91.1%Reduced
Baker Ellis Asset Management LLC1,273$617.2K0.09%+215+20.3%Added
Wakefield Asset Management LLLP1,276$618.6K0.19%+1,276New
Two Sigma Securities, LLC1,293$626.9K0.10%+1,293New
Koshinski Asset Management, Inc.1,298$629.3K0.05%−59−4.3%Reduced
Simplicity Wealth,LLC1,299$629.6K0.05%+581+80.9%Added
American Trust1,302$631.2K0.16%−201−13.4%Reduced
Zhang Financial LLC1,316$638.2K0.03%−3,315−71.6%Reduced
Alps Advisors Inc1,317$638.5K0.00%+529+67.1%Added
Fox Run Management, L.L.C.1,330$644.8K0.10%+1,330New
Pine Valley Investments Ltd Liability Co1,341$650.1K0.04%−86−6.0%Reduced
Farringdon Capital, Ltd.1,341$650.1K0.33%+1,341New
Hancock Whitney Corp1,343$651.1K0.02%−184−12.0%Reduced
West Family Investments, Inc.1,348$653.5K0.25%−1,304−49.2%Reduced
Nabity-Jensen Investment Management Inc1,348$653.5K0.52%00.0%Unchanged
Bay Colony Advisory Group, Inc d/b/a Bay Colony Advisors1,327$653.8K0.10%+275+26.1%Added
Paces Ferry Wealth Advisors, LLC1,352$655.5K0.33%+116+9.4%Added
Great Diamond Partners, LLC1,353$656.0K0.18%+338+33.3%Added
BankPlus Trust Department1,356$657.4K0.22%−23−1.7%Reduced
Prudent Man Advisors, LLC1,359$658.9K0.24%−403−22.9%Reduced
Hartford Funds Management Co LLC1,360$659.4K0.06%+239+21.3%Added
Catalyst Financial Partners LLC1,361$659.8K0.12%+236+21.0%Added
Holderness Investments Co1,364$661.3K0.15%+48+3.6%Added
Bourgeon Capital Management LLC1,367$662.7K0.14%+11+0.8%Added
Cyrus J. Lawrence, LLC1,373$665.0K2.52%−19,011−93.3%Reduced
Kessler Investment Group, LLC1,373$665.7K0.33%00.0%Unchanged
Vista Wealth Management Group, LLC1,380$669.0K0.04%+33+2.4%Added
Hantz Financial Services, Inc.1,384$671.0K0.01%+126+10.0%Added
NorthCrest Asset Manangement, LLC1,389$673.5K0.02%+96+7.4%Added
Accurate Wealth Management, LLC1,429$691.6K0.13%+512+55.8%Added
Legacy Wealth Asset Management, LLC1,429$692.8K0.19%−22−1.5%Reduced
SK Wealth Management, LLC1,457$695.7K0.37%00.0%Unchanged
Wolverine Trading, LLC1,415$697.2K0.02%−16,753−92.2%Reduced
Arete Wealth Advisors, LLC1,446$701.0K0.05%+215+17.5%Added
BKD Wealth Advisors, LLC1,448$702.0K0.02%+1,448New
Resonant Capital Advisors, LLC1,450$703.0K0.05%+183+14.4%Added
Sheaff Brock Investment Advisors, LLC1,454$704.9K0.06%+316+27.8%Added
Arkadios Wealth Advisors1,455$705.5K0.03%+374+34.6%Added
AdvisorNet Financial, Inc1,473$714.1K0.05%+117+8.6%Added
Harbor Investment Advisory, LLC1,474$714.6K0.07%−419−22.1%Reduced
SBI Securities Co., Ltd.1,479$717.0K0.02%−32−2.1%Reduced
Private Wealth Partners, LLC1,485$720.0K0.06%−10−0.7%Reduced
Mayflower Financial Advisors, LLC1,491$722.9K0.11%+10+0.7%Added
Arcataur Capital Management LLC1,496$725.3K0.25%−158−9.6%Reduced
Kensington Investment Counsel, LLC1,496$725.3K0.32%−60−3.9%Reduced
Strategic Blueprint, LLC1,498$726.3K0.04%+25+1.7%Added
Advisory Alpha, LLC1,514$734.0K0.02%+222+17.2%Added
Flagship Harbor Advisors, LLC1,535$744.2K0.04%+13+0.9%Added
IHT Wealth Management, LLC1,542$747.3K0.02%−242−13.6%Reduced
First Manhattan Co1,555$753.9K0.00%00.0%Unchanged
Rehmann Capital Advisory Group1,564$758.3K0.05%+48+3.2%Added
Reuter James Wealth Management, LLC1,567$759.7K0.13%−130−7.7%Reduced
Sava Infond d.o.o.1,570$761.2K0.15%−60−3.7%Reduced
Alliance Wealth Advisors, LLC1,573$762.6K0.20%+638+68.2%Added
First Pacific Financial1,581$766.5K0.16%−144−8.3%Reduced
Conning Inc.1,586$768.9K0.03%+172+12.2%Added
Perfromance Wealth Partners, LLC1,603$777.2K0.03%00.0%Unchanged
Eastern Bank1,610$780.6K0.02%−10−0.6%Reduced
Anchor Investment Management, LLC1,615$783.0K0.07%+209+14.9%Added
Campbell Newman Asset Management Inc1,631$790.7K0.07%00.0%Unchanged
Scientech Research LLC1,635$792.7K0.21%−355−17.8%Reduced
Exencial Wealth Advisors, LLC1,636$793.0K0.03%−72−4.2%Reduced
Summit Financial, LLC1,640$795.1K0.02%−183−10.0%Reduced
Altfest L J & Co Inc1,646$798.0K0.10%+975+145.3%Added
Vista Investment Management1,654$801.9K0.31%−18−1.1%Reduced
Menard Financial Group LLC1,782$802.0K0.53%+152+9.3%Added
Continuum Advisory, LLC1,665$807.2K0.10%+89+5.6%Added
Oxler Private Wealth LLC1,674$811.6K0.29%−110−6.2%Reduced
Gilder Gagnon Howe & Co LLC1,679$814.0K0.01%−28−1.6%Reduced
Raab & Moskowitz Asset Management LLC1,701$824.7K0.21%00.0%Unchanged
Renaissance Group LLC1,714$830.9K0.04%−1,468−46.1%Reduced
Triangle Securities Wealth Management1,718$832.9K0.21%−48−2.7%Reduced