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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,618
+81 vs. Q4 2024
Shares held
239.9M
+4.97M (+2.1%) vs. Q4 2024
Total value
$116.3B
+$21.7B (+23.0%) vs. Q4 2024
New holders
209
638 more added
Sold out
128
576 more reduced

26 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 1,618 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ1 2025: $116.3B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2024.

Institutions holding VRTX in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Prescott Group Capital Management, L.L.C.597$289.4K0.04%+597New
George Kaiser Family Foundation597$289.4K0.04%+597New
Massachusetts Wealth Management597$289.4K0.20%+597New
Sittner & Nelson, LLC598$289.9K0.12%00.0%Unchanged
Granite Bay Wealth Management, LLC600$291.0K0.10%−304−33.6%Reduced
Sage Capital Advisors,llc601$291.2K0.08%+48+8.7%Added
Resurgent Financial Advisors LLC601$291.4K0.17%+15+2.6%Added
Tritonpoint Wealth, LLC604$292.6K0.03%+83+15.9%Added
Alpha Zero LLC605$293.3K0.22%−5−0.8%Reduced
Kelly Lawrence W & Associates Inc605$293.3K0.07%00.0%Unchanged
Aries Wealth Management605$293.3K0.08%+605New
Carr Financial Group Corp608$294.8K0.10%+608New
Boston Trust Walden Corp610$295.7K0.00%−200−24.7%Reduced
RiverFront Investment Group, LLC612$296.7K0.01%+612New
TBH Global Asset Management, LLC613$297.3K0.06%+613New
First American Bank614$297.7K0.02%00.0%Unchanged
Nicolet Bankshares Inc617$299.1K0.06%−30−4.6%Reduced
MONECO Advisors, LLC619$300.3K0.03%+619New
Meridian Wealth Management, LLC620$300.6K0.01%+1+0.2%Added
Savvy Advisors, Inc.622$301.6K0.03%+622New
Perpetual Ltd623$302.0K0.00%+623New
Ignite Planners, LLC607$302.8K0.06%+607New
MBB Public Markets I LLC626$303.5K0.03%+626New
Custom Index Systems, LLC627$304.0K0.15%−591−48.5%Reduced
Versant Capital Management, Inc627$304.0K0.05%+297+90.0%Added
Mesirow Financial Investment Management, Inc.629$305.0K0.01%+61+10.7%Added
Diversified Trust Co632$306.4K0.01%+95+17.7%Added
Global Trust Asset Management, LLC633$306.7K0.19%−14−2.2%Reduced
May Hill Capital, LLC633$306.9K0.12%−15−2.3%Reduced
Empower Advisory Group, LLC635$307.9K0.00%−27−4.1%Reduced
Thoroughbred Financial Services, LLC637$308.0K0.02%+1+0.2%Added
Cromwell Holdings LLC640$310.3K0.20%−149−18.9%Reduced
Keudell/Morrison Wealth Management642$311.3K0.07%−4−0.6%Reduced
Moran Wealth Management, LLC644$312.2K0.01%−29,300−97.8%Reduced
Abundance Wealth Counselors646$313.0K0.07%+646New
Marshall Financial Group LLC648$314.2K0.07%−312−32.5%Reduced
PAX Financial Group, LLC652$316.1K0.06%+652New
Leeward Financial Partners, LLC658$319.0K0.12%−357−35.2%Reduced
Sanibel Captiva Trust Company, Inc.659$319.5K0.01%+16+2.5%Added
FourThought Financial Partners, LLC661$320.5K0.03%−31−4.5%Reduced
Costello Asset Management, INC665$322.4K0.13%+665New
Green Alpha Advisors, LLC668$323.9K0.35%−21−3.0%Reduced
Kornitzer Capital Management Inc668$323.9K0.01%+3+0.5%Added
KC Investment Advisors, LLC673$326.3K0.07%+46+7.3%Added
Fort Point Capital Partners LLC674$326.8K0.04%−146−17.8%Reduced
Boothbay Fund Management, LLC676$327.7K0.01%+676New
Onefund, LLC677$328.2K0.33%−8−1.2%Reduced
Fox Hill Wealth Management677$328.2K0.19%−1−0.1%Reduced
J2 Capital Management Inc678$328.7K0.30%+7+1.0%Added
Harmony Asset Management LLC680$329.7K0.14%−5,595−89.2%Reduced
William Mack & Associates, Inc.682$330.6K0.28%00.0%Unchanged
StoneX Group Inc.682$330.6K0.02%+12+1.8%Added
Delta Financial Advisors LLC682$330.6K0.12%+31+4.8%Added
Venture Visionary Partners LLC689$334.0K0.01%−1−0.1%Reduced
Essex Savings Bank691$335.0K0.08%−1−0.1%Reduced
Western Wealth Management, LLC691$335.0K0.02%−132−16.0%Reduced
Fairfield, Bush & Co.691$335.0K0.21%−88−11.3%Reduced
Kempen Capital Management N.V.698$338.4K0.00%−2,682−79.3%Reduced
Corient IA LLC700$339.4K0.24%+700New
Cynosure Management, LLC703$340.8K0.05%−60−7.9%Reduced
Loring Wolcott & Coolidge Fiduciary Advisors LLP694$341.7K0.00%00.0%Unchanged
Grimes & Company, Inc.706$342.4K0.01%+57+8.8%Added
Regions Financial Corp707$342.8K0.00%+51+7.8%Added
Seven Mile Advisory709$343.7K0.23%+23+3.4%Added
Investment Advisory Group, LLC717$347.6K0.12%+1+0.1%Added
Wedgewood Investors Inc720$349.1K0.41%−280−28.0%Reduced
Terra Nova Asset Management LLC720$349.1K0.27%00.0%Unchanged
Teamwork Financial Advisors, LLC723$350.5K0.05%−1,994−73.4%Reduced
Sivia Capital Partners, LLC726$351.9K0.16%+68+10.3%Added
Wealthspire Advisors, LLC730$353.9K0.00%−19−2.5%Reduced
Pinnacle Wealth Management Advisory Group, LLC731$354.4K0.03%+45+6.6%Added
LRI Investments, LLC732$354.8K0.03%+335+84.4%Added
Nicholas Hoffman & Company, LLC.732$354.9K0.01%00.0%Unchanged
Gsa Capital Partners LLP734$356.0K0.03%−1,255−63.1%Reduced
Edgestream Partners, L.P.738$357.8K0.01%−5,104−87.4%Reduced
Occidental Asset Management, LLC738$357.8K0.05%+738New
Polymer Capital Management (US) LLC739$358.3K0.11%−77−9.4%Reduced
Lewis Asset Management, LLC745$361.2K0.30%−5−0.7%Reduced
Everpar Advisors LLC748$362.6K0.19%+81+12.1%Added
Northstar Asset Management LLC750$363.6K0.09%00.0%Unchanged
Waterloo Capital, L.P.753$365.1K0.03%+753New
Financial Symmetry Inc755$366.2K0.22%00.0%Unchanged
RFG Advisory, LLC757$367.2K0.01%+82+12.1%Added
Newman Dignan & Sheerar, Inc.761$368.9K0.10%+31+4.2%Added
Relyea Zuckerberg Hanson LLC762$369.4K0.05%+214+39.1%Added
SeaCrest Wealth Management, LLC763$369.9K0.04%+763New
Harel Insurance Investments & Financial Services Ltd.766$371.0K0.00%−140−15.5%Reduced
Virtus Investment Advisers, Inc.773$374.8K0.10%+773New
Essex Financial Services, Inc.777$376.7K0.03%−24−3.0%Reduced
Cercano Management LLC780$378.2K0.01%00.0%Unchanged
Ausdal Financial Partners, Inc.780$378.2K0.03%+23+3.0%Added
One Wealth Capital Management, LLC782$379.1K0.20%+160+25.7%Added
BridgePort Financial Solutions, LLC793$384.5K0.17%−1−0.1%Reduced
Journey Strategic Wealth LLC794$384.9K0.01%+72+10.0%Added
LVW Advisors, LLC794$384.9K0.05%+28+3.7%Added
Childress Capital Advisors, LLC800$388.1K0.11%−4−0.5%Reduced
CoreCap Advisors, LLC801$388.3K0.02%−425−34.7%Reduced
PFW Advisors LLC801$388.3K0.12%00.0%Unchanged
Zullo Investment Group, Inc.803$389.3K0.17%+1+0.1%Added
Sentry Investment Management LLC821$390.0K0.26%−245−23.0%Reduced