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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,617
+80 vs. Q4 2024
Shares held
239.9M
+4.97M (+2.1%) vs. Q4 2024
Total value
$116.3B
+$21.7B (+23.0%) vs. Q4 2024
New holders
208
638 more added
Sold out
128
576 more reduced

26 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 1,617 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ1 2025: $116.3B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2024.

Institutions holding VRTX in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Bank of America Corp2,864,998$1.39B0.12%+445,645+18.4%Added
Price T Rowe Associates Inc2,917,227$1.41B0.17%+1,226,527+72.5%Added
Amundi3,098,869$1.50B0.55%−182,336−5.6%Reduced
Norges Bank3,364,150$1.63B0.23%−50,174−1.5%Reduced
Morgan Stanley3,408,520$1.65B0.12%+237,133+7.5%Added
Loomis Sayles & Co L P3,748,331$1.82B2.63%−24,458−0.6%Reduced
Alliancebernstein L.P.3,953,512$1.92B0.69%+33,492+0.9%Added
Jennison Associates LLC5,062,442$2.45B1.72%+744,680+17.2%Added
Wellington Management Group LLP5,454,748$2.64B0.51%−461,336−7.8%Reduced
Geode Capital Management, LLC5,761,760$2.78B0.22%+113,524+2.0%Added
FMR LLC7,727,184$3.75B0.24%−1,491,862−16.2%Reduced
JPMorgan Chase & Co7,755,645$3.76B0.29%+1,442,538+22.8%Added
State Street Corp11,788,657$5.72B0.24%−190,748−1.6%Reduced
Capital Research Global Investors14,536,344$7.05B1.53%+4,107,393+39.4%Added
BlackRock, Inc.21,782,933$10.6B0.22%−42,537−0.2%Reduced
Vanguard Group Inc23,491,161$11.4B0.21%+232,873+1.0%Added
Capital World Investors28,533,308$13.8B2.24%+207,613+0.7%Added
Proequities, Inc.0$00.00%−6,677−100.0%Sold out
Jupiter Asset Management Ltd0$00.00%−78,166−100.0%Sold out
Voloridge Investment Management, LLC0$00.00%−69,712−100.0%Sold out
Twinbeech Capital LP0$00.00%−55,249−100.0%Sold out
Group One Trading, L.P.0$00.00%−30,402−100.0%Sold out
Capitolis Liquid Global Markets LLC0$00.00%−25,000−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−22,794−100.0%Sold out
TruWealth Advisors, LLC0$00.00%−22,241−100.0%Sold out
Railway Pension Investments Ltd0$00.00%−21,600−100.0%Sold out
Wealth High Governance Capital Ltda0$00.00%−15,528−100.0%Sold out
Sivik Global Healthcare LLC0$00.00%−13,000−100.0%Sold out
Engineers Gate Manager LP0$00.00%−11,599−100.0%Sold out
Navellier & Associates Inc0$00.00%−11,427−100.0%Sold out
Readystate Asset Management LP0$00.00%−11,058−100.0%Sold out
Patton Fund Management, Inc.0$00.00%−10,084−100.0%Sold out
HRT Financial LP0$00.00%−10,030−100.0%Sold out
BW Gestao de Investimentos Ltda.0$00.00%−9,472−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−9,463−100.0%Sold out
Arrowstreet Capital, Limited Partnership0$00.00%−9,265−100.0%Sold out
Capstone Investment Advisors, LLC0$00.00%−7,980−100.0%Sold out
Brevan Howard Capital Management LP0$00.00%−7,270−100.0%Sold out
Algert Global LLC0$00.00%−7,177−100.0%Sold out
Aubrey Capital Management Ltd0$00.00%−6,900−100.0%Sold out
Winton Group Ltd0$00.00%−6,884−100.0%Sold out
Copperwynd Financial, LLC0$00.00%−5,556−100.0%Sold out
Financial Advisors Network, Inc.0$00.00%−5,518−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−5,385−100.0%Sold out
First Hawaiian Bank0$00.00%−4,942−100.0%Sold out
ING Groep NV0$00.00%−4,784−100.0%Sold out
Seizert Capital Partners, LLC0$00.00%−4,165−100.0%Sold out
Abc Arbitrage SA0$00.00%−3,750−100.0%Sold out
Axecap Investments, LLC0$00.00%−3,676−100.0%Sold out
Jackson Wealth Management, LLC0$00.00%−3,502−100.0%Sold out
111 Capital0$00.00%−3,304−100.0%Sold out
Fieldview Capital Management, LLC0$00.00%−3,296−100.0%Sold out
SWS Partners0$00.00%−3,267−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−3,200−100.0%Sold out
Retirement Guys Formula LLC0$00.00%−2,990−100.0%Sold out
Anfield Capital Management, LLC0$00.00%−2,977−100.0%Sold out
Twin Capital Management Inc0$00.00%−2,933−100.0%Sold out
XTX Topco Ltd0$00.00%−2,530−100.0%Sold out
Advisory Resource Group0$00.00%−2,461−100.0%Sold out
InTrack Investment Management Inc0$00.00%−2,132−100.0%Sold out
Acadian Asset Management LLC0$00.00%−2,145−100.0%Sold out
Stevens Capital Management LP0$00.00%−2,058−100.0%Sold out
Phoenix Holdings Ltd.0$00.00%−2,025−100.0%Sold out
Knott David M Jr0$00.00%−2,000−100.0%Sold out
Lecap Asset Management Ltd0$00.00%−1,944−100.0%Sold out
JSF Financial, LLC0$00.00%−1,866−100.0%Sold out
Westfield Capital Management Co LP0$00.00%−1,742−100.0%Sold out
Blueshift Asset Management, LLC0$00.00%−1,729−100.0%Sold out
Colrain Capital LLC0$00.00%−1,696−100.0%Sold out
Dark Forest Capital Management LP0$00.00%−1,657−100.0%Sold out
Contravisory Investment Management, Inc.0$00.00%−1,644−100.0%Sold out
Clare Market Investments LLC0$00.00%−1,490−100.0%Sold out
Net Worth Advisory Group0$00.00%−1,452−100.0%Sold out
TKG Advisors, LLC0$00.00%−1,247−100.0%Sold out
Asahi Life Asset Management Co., Ltd.0$00.00%−1,280−100.0%Sold out
Corton Capital Inc.0$00.00%−1,278−100.0%Sold out
G&S Capital LLC0$00.00%−1,267−100.0%Sold out
Oversea-Chinese Banking CORP Ltd0$00.00%−1,233−100.0%Sold out
Nicholas Investment Partners, LP0$00.00%−1,218−100.0%Sold out
DRW Securities, LLC0$00.00%−1,189−100.0%Sold out
Mitchell Capital Management Co0$00.00%−1,128−100.0%Sold out
Wela Strategies, Inc.0$00.00%−46,113−100.0%Sold out
Flow Traders U.S. LLC0$00.00%−1,115−100.0%Sold out
Convergence Investment Partners, LLC0$00.00%−1,095−100.0%Sold out
Axxcess Wealth Management, LLC0$00.00%−1,052−100.0%Sold out
Bridgefront Capital, LLC0$00.00%−967−100.0%Sold out
Symphony Financial, Ltd. Co.0$00.00%−859−100.0%Sold out
Cassia Capital Partners, LLC0$00.00%−895−100.0%Sold out
Armis Advisers, LLC0$00.00%−892−100.0%Sold out
Pettyjohn, Wood & White, Inc0$00.00%−889−100.0%Sold out
Aveo Capital Partners, LLC0$00.00%−878−100.0%Sold out
Catalina Capital Group, LLC0$00.00%−873−100.0%Sold out
Columbia Asset Management0$00.00%−802−100.0%Sold out
Virtus ETF Advisers LLC0$00.00%−753−100.0%Sold out
Bridgewater Associates, LP0$00.00%−710−100.0%Sold out
Williams & Novak, LLC0$00.00%−687−100.0%Sold out
Inceptionr LLC0$00.00%−665−100.0%Sold out
PKS Advisory Services, LLC0$00.00%−595−100.0%Sold out
Terry L. Blaker0$00.00%−592−100.0%Sold out
World Equity Group, Inc.0$00.00%−582−100.0%Sold out