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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,617
+80 vs. Q4 2024
Shares held
239.9M
+4.97M (+2.1%) vs. Q4 2024
Total value
$116.3B
+$21.7B (+23.0%) vs. Q4 2024
New holders
208
638 more added
Sold out
128
576 more reduced

26 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 1,617 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ1 2025: $116.3B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2024.

Institutions holding VRTX in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Fisher Funds Management LTD14,331$6.95M0.17%00.0%Unchanged
Toroso Investments, LLC14,391$6.98M0.06%−3,962−21.6%Reduced
Madison Asset Management, LLC14,396$6.98M0.08%−126−0.9%Reduced
CIBC World Markets Inc.14,485$7.02M0.02%−988−6.4%Reduced
Trifecta Capital Advisors, LLC14,538$7.05M1.48%+573+4.1%Added
Northwest & Ethical Investments L.P.14,559$7.06M0.19%−13,263−47.7%Reduced
Investment Management Corp of Ontario14,767$7.16M0.15%−2,530−14.6%Reduced
Gulf International Bank (UK) Ltd14,908$7.23M0.25%−4,524−23.3%Reduced
Quantitative Investment Management, LLC14,997$7.27M0.67%+14,997New
Jane Street Group, LLC15,008$7.28M0.01%+454+3.1%Added
Princeton Capital Management LLC15,036$7.29M2.57%−138−0.9%Reduced
Mercer Global Advisors Inc15,061$7.30M0.02%+1,053+7.5%Added
Man Group plc15,184$7.36M0.02%−73,542−82.9%Reduced
Princeton Global Asset Management LLC15,211$7.37M1.46%+79+0.5%Added
Connor, Clark & Lunn Investment Management Ltd.15,253$7.39M0.03%−5,750−27.4%Reduced
Puzo Michael J15,285$7.41M2.12%+1,176+8.3%Added
Park Avenue Securities LLC15,339$7.44M0.09%+885+6.1%Added
PEAK6 LLC15,466$7.50M0.29%+6,346+69.6%Added
Fulcrum Capital LLC15,578$7.55M1.67%+84+0.5%Added
NBW Capital LLC15,646$7.59M1.68%−4,592−22.7%Reduced
Hartford Investment Management Co15,670$7.60M0.26%−251−1.6%Reduced
Metis Global Partners, LLC15,699$7.61M0.21%+1,814+13.1%Added
Torray LLC15,721$7.62M1.14%−287−1.8%Reduced
Nia Impact Advisors, LLC15,932$7.72M2.87%00.0%Unchanged
Baird Financial Group, Inc.16,001$7.76M0.01%−370−2.3%Reduced
Ameritas Investment Partners, Inc.16,019$7.77M0.27%+117+0.7%Added
Vident Advisory, LLC16,078$7.79M0.11%−3,756−18.9%Reduced
Beacon Pointe Advisors, LLC16,225$7.87M0.09%+22+0.1%Added
Cambridge Investment Research Advisors, Inc.16,331$7.92M0.03%+3,750+29.8%Added
Gabelli Funds LLC16,350$7.93M0.06%−1,324−7.5%Reduced
Janney Capital Management LLC16,507$8.00M0.55%−82−0.5%Reduced
Oddo BHF Asset Management SAS16,697$8.10M0.33%−1,076−6.1%Reduced
UniSuper Management Pty Ltd16,837$8.16M0.06%+563+3.5%Added
Silvercrest Asset Management Group LLC16,846$8.17M0.06%−502−2.9%Reduced
First American Trust, FSB17,011$8.25M0.76%+514+3.1%Added
Massmutual Trust Co FSB17,016$8.25M0.24%+10,774+172.6%Added
Envestnet Portfolio Solutions, Inc.17,022$8.25M0.03%−2,227−11.6%Reduced
Fiduciary Trust Co17,264$8.37M0.11%+4,104+31.2%Added
QRG Capital Management, Inc.17,393$8.43M0.09%+831+5.0%Added
Kentucky Retirement Systems17,659$8.56M0.26%−77−0.4%Reduced
Broderick Brian C18,001$8.73M1.78%+1,127+6.7%Added
Grandfield & Dodd, LLC18,146$8.80M0.55%+1,182+7.0%Added
Telos Capital Management, Inc.18,174$8.81M0.96%+547+3.1%Added
Generali Asset Management SPA SGR18,332$8.89M0.22%−4,529−19.8%Reduced
M&T Bank Corp18,364$8.90M0.03%−162−0.9%Reduced
Spire Wealth Management18,576$9.01M0.29%+72+0.4%Added
Procyon Private Wealth Partners, LLC18,598$9.02M0.55%+3,963+27.1%Added
Longbow Finance SA18,686$9.06M1.09%−4,013−17.7%Reduced
Bogart Wealth, LLC19,167$9.29M0.44%−3,092−13.9%Reduced
Anderson Hoagland & Co19,823$9.36M1.11%−1,352−6.4%Reduced
First Horizon Advisors, Inc.19,315$9.36M0.26%+17,116+778.4%Added
Federation des caisses Desjardins du Quebec19,374$9.39M0.05%−33,862−63.6%Reduced
Jefferies Financial Group Inc.19,484$9.45M0.16%+5,500+39.3%Added
Heirloom Wealth Management19,553$9.48M2.72%+760+4.0%Added
Warren Averett Asset Management, LLC19,836$9.62M0.12%+15,888+402.4%Added
Lombard Odier Asset Management (Europe) Ltd19,930$9.66M0.78%+957+5.0%Added
Susquehanna Fundamental Investments, LLC19,986$9.69M0.16%+15,886+387.5%Added
Prudential PLC20,067$9.73M0.05%−5,451−21.4%Reduced
Norinchukin Bank, The20,077$9.73M0.18%+6,120+43.8%Added
Kennedy Capital Management, Inc.20,457$9.92M0.24%−3,158−13.4%Reduced
Mizuho Securities USA LLC20,561$9.97M0.22%−3,847−15.8%Reduced
Camden National Bank20,666$10.0M1.49%−271−1.3%Reduced
AIMZ Investment Advisors, LLC20,951$10.2M3.55%−159−0.8%Reduced
Azimuth Capital Investment Management LLC21,243$10.3M0.41%−898−4.1%Reduced
Galvin, Gaustad & Stein, LLC21,361$10.4M0.93%−367−1.7%Reduced
Polar Asset Management Partners Inc.21,594$10.5M0.35%−35,406−62.1%Reduced
Oppenheimer Asset Management Inc.21,694$10.5M0.13%+1,166+5.7%Added
Ieq Capital, LLC22,005$10.7M0.08%+3,782+20.8%Added
Walleye Trading LLC22,021$10.7M0.30%+22,021New
Oregon Public Employees Retirement Fund22,084$10.7M0.21%+100.0%Added
SG Americas Securities, LLC22,273$10.8M0.04%+17,502+366.8%Added
HealthInvest Partners AB22,808$11.1M4.88%+551+2.5%Added
Citizens Financial Group Inc22,810$11.1M0.22%+116+0.5%Added
GW Henssler & Associates Ltd22,811$11.1M0.63%−1,405−5.8%Reduced
Somerville Kurt F22,876$11.1M1.93%+2,484+12.2%Added
Foster Victor Wealth Advisors, LLC22,924$11.1M0.89%−1,664−6.8%Reduced
TownSquare Capital, LLC22,986$11.1M0.12%+5,859+34.2%Added
Atria Investments LLC23,282$11.3M0.14%+4,684+25.2%Added
Nordea Investment Management AB23,455$11.4M0.01%−318,974−93.2%Reduced
Cary Street Partners Financial LLC23,706$11.5M0.36%−183−0.8%Reduced
Capital Group Investment Management Pte. Ltd.23,852$11.6M2.36%+271+1.1%Added
Allianz SE23,947$11.6M0.31%−54−0.2%Reduced
Avanza Fonder AB24,020$11.6M0.38%−4,138−14.7%Reduced
Modera Wealth Management, LLC23,973$11.6M0.16%−637−2.6%Reduced
Aptus Capital Advisors, LLC24,240$11.8M0.13%+2,072+9.3%Added
Profund Advisors LLC24,671$12.0M0.52%−3,903−13.7%Reduced
Transform Wealth, LLC24,728$12.0M0.73%−172−0.7%Reduced
Pinnacle Associates Ltd24,898$12.1M0.18%+12,002+93.1%Added
Apollon Wealth Management, LLC25,127$12.2M0.27%+12,955+106.4%Added
Biondo Investment Advisors, LLC25,149$12.2M1.73%−131−0.5%Reduced
Meiji Yasuda Life Insurance Co25,182$12.2M0.24%−195−0.8%Reduced
SIH Partners, LLLP25,388$12.3M1.08%+25,388New
Capital Group Private Client Services, Inc.25,632$12.4M0.12%+25,632New
Los Angeles Capital Management LLC25,723$12.5M0.06%+24,421+1,875.7%Added
Fifth Third Bancorp25,809$12.5M0.05%−294−1.1%Reduced
Fagan Associates, Inc.26,285$12.7M2.13%−233−0.9%Reduced
ARK Investment Management LLCSuperinvestorARK Invest26,344$12.8M0.13%+994+3.9%Added
Churchill Management Corp26,388$12.8M0.16%−19,069−41.9%Reduced
South Dakota Investment Council26,403$12.8M0.26%−1,965−6.9%Reduced
Yousif Capital Management, LLC26,421$12.8M0.15%−664−2.5%Reduced