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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,617
+80 vs. Q4 2024
Shares held
239.9M
+4.97M (+2.1%) vs. Q4 2024
Total value
$116.3B
+$21.7B (+23.0%) vs. Q4 2024
New holders
208
638 more added
Sold out
128
576 more reduced

26 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 1,617 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ1 2025: $116.3B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2024.

Institutions holding VRTX in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Ashford Capital Management Inc8,192$3.97M0.51%+273+3.4%Added
Tokio Marine Asset Management Co Ltd8,205$3.98M0.14%+131+1.6%Added
Benjamin Edwards Inc8,206$3.98M0.06%+827+11.2%Added
Privium Fund Management B.V.8,300$4.02M1.05%+8,300New
Commerce Bank8,343$4.04M0.03%−295−3.4%Reduced
Sepio Capital, LP8,360$4.05M0.32%+1,311+18.6%Added
Cutter & CO Brokerage, Inc.8,407$4.08M0.96%−3,355−28.5%Reduced
Level Four Advisory Services, LLC8,436$4.09M0.17%+969+13.0%Added
Tema ETFs LLC8,448$4.10M1.22%−2,533−23.1%Reduced
Kovitz Investment Group Partners, LLC8,469$4.11M0.02%−8,712−50.7%Reduced
Synovus Financial Corp8,506$4.12M0.05%−2,648−23.7%Reduced
Richard Bernstein Advisors LLC8,606$4.17M0.10%−444−4.9%Reduced
Intech Investment Management LLC8,697$4.22M0.04%−15,953−64.7%Reduced
Sigma Investment Counselors Inc8,751$4.24M0.26%−251−2.8%Reduced
AG2R la Mondiale Gestion D'Actifs9,601$4.24M0.23%+9,601New
Twin Tree Management, LP8,773$4.25M0.09%+8,773New
Bensler, LLC8,835$4.28M0.54%−133−1.5%Reduced
Empirical Finance, LLC8,946$4.34M0.26%+133+1.5%Added
Central Trust Co8,985$4.36M0.11%−806−8.2%Reduced
Hedeker Wealth, LLC9,007$4.37M1.17%+9,007New
Virtu Financial LLC9,064$4.39M0.24%+1,543+20.5%Added
Bulltick Wealth Management, LLC9,089$4.41M1.17%+17+0.2%Added
Te Ahumairangi Investment Management Ltd9,118$4.42M0.94%−3,295−26.5%Reduced
Howe & Rusling Inc9,126$4.42M0.37%+232+2.6%Added
EFG Asset Management (North America) Corp.9,132$4.43M0.74%−2,923−24.2%Reduced
NewEdge Wealth, LLC9,308$4.51M0.08%−32,139−77.5%Reduced
Pinnacle Financial Partners Inc9,354$4.53M0.09%+3,158+51.0%Added
Ascent Group, LLC9,442$4.58M0.20%−1,345−12.5%Reduced
Brinker Capital Investments, LLC9,573$4.64M0.05%+610+6.8%Added
Orion Portfolio Solutions, LLC9,573$4.64M0.05%+610+6.8%Added
TD Waterhouse Canada Inc.9,623$4.65M0.04%+783+8.9%Added
Baker Chad R9,740$4.72M0.96%00.0%Unchanged
E Fund Management Co., Ltd.9,884$4.79M0.23%+3,448+53.6%Added
Shorepoint Capital Partners LLC10,090$4.89M1.11%+280+2.9%Added
Dakota Wealth Management10,147$4.92M0.12%+2,739+37.0%Added
Crestwood Advisors Group LLC10,275$4.98M0.09%+4,476+77.2%Added
Banque Cantonale Vaudoise10,298$4.99M0.22%+10,298New
Fayez Sarofim & Co10,392$5.04M0.01%00.0%Unchanged
Morse Asset Management, Inc10,461$5.07M1.28%−94−0.9%Reduced
Siemens Fonds Invest GmbH10,608$5.14M0.35%+10,608New
Boston Private Wealth LLC10,636$5.16M0.21%−4,527−29.9%Reduced
HB Wealth Management, LLC10,656$5.17M0.04%+1,889+21.5%Added
Mark Sheptoff Financial Planning, LLC10,671$5.17M2.85%−400−3.6%Reduced
GWM Advisors LLC10,943$5.31M0.03%−1,708−13.5%Reduced
Generali Investments CEE, investicni spolecnost, a.s.11,030$5.35M0.50%00.0%Unchanged
Traynor Capital Management, Inc.11,044$5.35M0.45%+5,282+91.7%Added
GAM Holding AG11,045$5.35M0.42%+988+9.8%Added
Bleakley Financial Group, LLC11,322$5.49M0.18%+2,847+33.6%Added
BTC Capital Management, Inc.11,339$5.50M0.50%+309+2.8%Added
Banque Pictet & Cie SA11,373$5.51M0.06%−670−5.6%Reduced
Northwest Bancshares, Inc.11,419$5.54M1.02%−302−2.6%Reduced
Ethic Inc.11,437$5.54M0.11%−11,553−50.3%Reduced
Diversify Wealth Management, LLC11,012$5.54M0.41%+1,239+12.7%Added
Agf Management Ltd11,483$5.57M0.03%+10,145+758.2%Added
E. Ohman J:or Asset Management AB11,490$5.57M0.15%−250−2.1%Reduced
Great Valley Advisor Group, Inc.11,583$5.62M0.12%−9,010−43.8%Reduced
BI Asset Management Fondsmaeglerselskab A/S11,728$5.69M0.06%−4,593−28.1%Reduced
SummitTX Capital, L.P.11,743$5.69M0.25%+11,743New
Codex Capital Asset Management L.L.C.11,750$5.70M2.68%00.0%Unchanged
Slow Capital, Inc.11,834$5.74M0.77%+198+1.7%Added
Greenwood Capital Associates LLC11,893$5.77M0.78%−6,572−35.6%Reduced
United Capital Financial Advisers, LLC11,966$5.80M0.05%+602+5.3%Added
Kidder Stephen W11,966$5.80M1.81%+1,718+16.8%Added
Bamco Inc12,000$5.82M0.02%−6,000−33.3%Reduced
New Mexico Educational Retirement Board12,000$5.82M0.21%−300−2.4%Reduced
Maryland State Retirement & Pension System12,091$5.86M0.14%−1,841−13.2%Reduced
Keybank National Association12,201$5.92M0.02%+83+0.7%Added
Kayne Anderson Rudnick Investment Management LLC12,234$5.93M0.01%−40−0.3%Reduced
Americana Partners, LLC12,237$5.93M0.23%+92+0.8%Added
Sterling Capital Management LLC12,374$6.00M0.09%+375+3.1%Added
Vestmark Advisory Solutions, Inc.12,388$6.01M0.15%+6,595+113.8%Added
Chicago Capital, LLC12,406$6.01M0.17%+188+1.5%Added
Forte Capital LLC12,452$6.04M0.72%+495+4.1%Added
Covenant Asset Management, LLC12,542$6.08M1.53%−85−0.7%Reduced
Compagnie Lombard Odier SCmA12,565$6.09M0.07%+3,000+31.4%Added
Meiji Yasuda Asset Management Co Ltd.12,646$6.13M0.25%−617−4.7%Reduced
Avantax Advisory Services, Inc.12,674$6.14M0.04%+1,203+10.5%Added
Alberta Investment Management Corp12,686$6.15M0.04%+12,686New
Impact Asset Management GmbH12,770$6.19M2.43%−120−0.9%Reduced
Cornerstone Advisors, LLC13,000$6.30M0.27%00.0%Unchanged
Northwestern Mutual Wealth Management Co13,037$6.32M0.01%+490+3.9%Added
Tower Research Capital LLC (TRC)13,116$6.33M0.19%−7,564−36.6%Reduced
New Age Alpha Advisors, LLC13,137$6.37M0.29%−170−1.3%Reduced
Kestra Advisory Services, LLC13,210$6.40M0.03%−3,048−18.7%Reduced
Verition Fund Management LLC13,252$6.42M0.04%−5,578−29.6%Reduced
Fred Alger Management, LLC13,324$6.46M0.04%+8,062+153.2%Added
Vinva Investment Management Ltd13,137$6.47M0.26%+9,625+274.1%Added
Shell Asset Management Co13,372$6.48M0.31%−1,285−8.8%Reduced
Captrust Financial Advisors13,530$6.56M0.02%+1,482+12.3%Added
Securian Asset Management, Inc13,598$6.59M0.20%−211−1.5%Reduced
Omers Administration Corp13,654$6.62M0.06%−88−0.6%Reduced
Knuff & Co LLC13,825$6.70M2.25%−116−0.8%Reduced
Baldwin Investment Management, LLC13,830$6.71M0.81%+1,271+10.1%Added
Cinctive Capital Management LP13,891$6.73M0.54%+13,891New
Motley Fool Asset Management LLC13,919$6.75M0.38%+435+3.2%Added
Sequoia Financial Advisors, LLC13,931$6.75M0.05%+1,041+8.1%Added
Liontrust Investment Partners LLP14,043$6.81M0.11%−3,986−22.1%Reduced
Wiley Bros.-Aintree Capital, LLC13,953$6.88M0.07%+881+6.7%Added
Pinebridge Investments, L.P.14,196$6.88M0.06%−252−1.7%Reduced
Cresset Asset Management, LLC14,327$6.95M0.03%−1,691−10.6%Reduced