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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 2 sales; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,617
+80 vs. Q4 2024
Shares held
239.9M
+4.97M (+2.1%) vs. Q4 2024
Total value
$116.3B
+$21.7B (+23.0%) vs. Q4 2024
New holders
208
638 more added
Sold out
128
576 more reduced

26 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 1,617 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ1 2025: $116.3B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2024.

Institutions holding VRTX in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Segment Wealth Management, LLC5,692$2.76M0.19%+11+0.2%Added
Signaturefd, LLC5,705$2.77M0.05%+656+13.0%Added
Fidelis Capital Partners, LLC5,604$2.77M0.29%+84+1.5%Added
Advisory Services Network, LLC5,713$2.77M0.05%−1,083−15.9%Reduced
Voleon Capital Management LP5,753$2.79M0.22%−7,475−56.5%Reduced
Greenleaf Trust5,766$2.80M0.03%+272+5.0%Added
Leonteq Securities AG5,820$2.80M0.21%−836−12.6%Reduced
Freemont Management S.A.5,800$2.81M1.11%−600−9.4%Reduced
HM Payson & Co5,821$2.82M0.05%−914−13.6%Reduced
McGuire Investment Group, LLC5,831$2.83M0.42%−178−3.0%Reduced
BNP Paribas5,834$2.83M0.12%−350−5.7%Reduced
Ballentine Partners, LLC5,837$2.83M0.05%+247+4.4%Added
Freedom Day Solutions, LLC5,841$2.83M0.87%−58−1.0%Reduced
Illumine Investment Management, LLC5,854$2.84M2.32%+78+1.4%Added
Plato Investment Management Ltd5,825$2.85M0.24%−820−12.3%Reduced
LMR Partners LLP5,889$2.86M0.06%−87,912−93.7%Reduced
Venturi Wealth Management, LLC5,905$2.86M0.15%−207−3.4%Reduced
Highview Capital Management LLC5,917$2.87M1.20%+146+2.5%Added
Tiaa Trust, National Association5,923$2.87M0.01%+160+2.8%Added
Change Path, LLC5,983$2.90M0.09%+628+11.7%Added
Diversify Advisory Services, LLC5,773$2.91M0.18%+827+16.7%Added
Broadleaf Partners, LLC5,996$2.91M0.76%−10,927−64.6%Reduced
Cohen Klingenstein LLC6,000$2.91M0.11%00.0%Unchanged
North Star Asset Management Inc6,019$2.92M0.13%+196+3.4%Added
Northeast Financial Consultants Inc6,040$2.93M0.13%00.0%Unchanged
United Services Automobile Association5,953$2.93M0.09%+5,953New
Scotia Capital Inc.6,072$2.94M0.02%−695−10.3%Reduced
Ofi Invest Asset Management6,595$2.96M0.08%+399+6.4%Added
B&L Asset Management LLC6,148$2.98M1.95%−35−0.6%Reduced
Crossmark Global Holdings, Inc.6,174$2.99M0.05%−33−0.5%Reduced
Oppenheimer & Co Inc6,201$3.01M0.05%−1,428−18.7%Reduced
CWA Asset Management Group, LLC6,205$3.01M0.14%+81+1.3%Added
Harbour Capital Advisors, LLC6,222$3.01M0.74%−20−0.3%Reduced
Triasima Portfolio Management inc.6,213$3.01M0.59%−5,447−46.7%Reduced
TD Private Client Wealth LLC6,225$3.02M0.08%+8+0.1%Added
Little House Capital LLC6,307$3.06M0.84%+1,573+33.2%Added
Lindbrook Capital, LLC6,308$3.06M0.28%+5,202+470.3%Added
Ostrum Asset Management6,346$3.08M0.16%−13−0.2%Reduced
Stonegate Investment Group, LLC6,356$3.08M0.08%−153−2.4%Reduced
Meeder Advisory Services, Inc.6,360$3.08M0.18%+753+13.4%Added
Sandy Spring Bank6,391$3.10M0.13%+1,615+33.8%Added
RSM US Wealth Management LLC6,393$3.10M0.05%+301+4.9%Added
CIBC Private Wealth Group, LLC6,562$3.10M0.01%+508+8.4%Added
Brighton Jones LLC6,421$3.11M0.10%+1,994+45.0%Added
Draper Asset Management, LLC6,431$3.12M2.45%+98+1.5%Added
Condor Capital Management6,528$3.16M0.29%00.0%Unchanged
Vision Capital Management, Inc.6,565$3.18M0.46%+1,541+30.7%Added
Miracle Mile Advisors, LLC6,568$3.18M0.06%+785+13.6%Added
Andrew Hill Investment Advisors, Inc.6,573$3.19M3.08%+19+0.3%Added
Brown Advisory Inc6,581$3.19M0.00%+739+12.6%Added
Chase Investment Counsel Corp6,596$3.20M1.17%−372−5.3%Reduced
Groupe la Francaise6,364$3.20M0.07%+741+13.2%Added
Wedbush Securities Inc6,603$3.20M0.12%+317+5.0%Added
Howard Capital Management Inc.6,636$3.22M0.08%−1,021−13.3%Reduced
Atria Wealth Solutions, Inc.6,656$3.23M0.04%−556−7.7%Reduced
Wahed Invest LLC6,663$3.23M0.56%+6,663New
Nikko Asset Management Americas, Inc.6,672$3.23M0.04%−707−9.6%Reduced
Hennion & Walsh Asset Management, Inc.6,795$3.29M0.15%−1,331−16.4%Reduced
Squarepoint Ops LLC6,895$3.34M0.01%−2,197−24.2%Reduced
Delaney Dennis R6,903$3.35M1.82%+433+6.7%Added
Kinneret Advisory, LLC6,905$3.35M0.34%−23−0.3%Reduced
Mission Wealth Management, LP6,911$3.35M0.08%+859+14.2%Added
Glenview Trust Co6,920$3.35M0.07%+30+0.4%Added
Sand Hill Global Advisors, LLC6,925$3.36M0.14%+6,925New
Impax Asset Management Group plc6,999$3.39M0.02%+75+1.1%Added
Dempze Nancy E7,063$3.42M2.06%+986+16.2%Added
Fiera Capital Corp7,092$3.44M0.01%+382+5.7%Added
Bokf, NA7,100$3.44M0.06%−685−8.8%Reduced
Thompson Siegel & Walmsley LLC7,109$3.45M0.06%−130−1.8%Reduced
Joseph Group Capital Management7,126$3.45M1.32%+704+11.0%Added
Notis-McConarty Edward7,275$3.53M1.81%+756+11.6%Added
First National Bank of Mount Dora, Trust Investment Services7,349$3.56M0.87%−4,882−39.9%Reduced
Davidson Capital Management Inc.7,420$3.60M0.98%+524+7.6%Added
Private Advisor Group, LLC7,452$3.61M0.02%+242+3.4%Added
Bessemer Group Inc7,484$3.63M0.01%+307+4.3%Added
Allstate Corp7,487$3.63M0.11%−128−1.7%Reduced
Kentucky Retirement Systems Insurance Trust Fund7,522$3.65M0.26%−756−9.1%Reduced
Sumitomo Life Insurance Co7,537$3.65M0.13%−76−1.0%Reduced
SFMG, LLC7,538$3.65M0.29%−111−1.5%Reduced
Cavalier Investments, LLC7,573$3.67M1.25%−12−0.2%Reduced
EagleClaw Capital Managment, LLC7,595$3.68M0.58%−35−0.5%Reduced
CWM, LLC7,684$3.73M0.01%+1,403+22.3%Added
GLOBALT Investments LLC7,695$3.73M0.15%−293−3.7%Reduced
Linden Thomas Advisory Services, LLC7,733$3.75M0.49%+292+3.9%Added
Leavell Investment Management, Inc.7,734$3.75M0.19%+1,423+22.5%Added
Duncker Streett & Co Inc7,747$3.76M0.74%+84+1.1%Added
Parsons Capital Management Inc7,768$3.77M0.21%+735+10.5%Added
Hamilton Capital Partners Inc.7,774$3.77M0.24%−337−4.2%Reduced
Transamerica Financial Advisors, Inc.7,851$3.81M0.39%−101−1.3%Reduced
Johnson Investment Counsel Inc7,919$3.84M0.04%+36+0.5%Added
Peloton Wealth Strategists7,954$3.86M1.61%+1,920+31.8%Added
Thematics Asset Management7,956$3.86M0.20%+7,801+5,032.9%Added
Paradigm Financial Partners, LLC7,964$3.86M0.48%−305−3.7%Reduced
J.P. Marvel Investment Advisors, LLC7,992$3.87M0.67%+1,600+25.0%Added
Griffin Asset Management, Inc.8,017$3.89M0.48%−115−1.4%Reduced
Lockheed Martin Investment Management Co8,100$3.93M0.16%−190−2.3%Reduced
PDT Partners, LLC8,116$3.93M0.28%−1,687−17.2%Reduced
Baldwin Brothers Inc8,119$3.94M0.28%−878−9.8%Reduced
Associated Banc-Corp8,163$3.96M0.12%−665−7.5%Reduced
Northwestern Mutual Investment Management Company, LLC8,167$3.96M0.06%−10−0.1%Reduced