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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 2 sales; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2025

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,617
+80 vs. Q4 2024
Shares held
239.9M
+4.97M (+2.1%) vs. Q4 2024
Total value
$116.3B
+$21.7B (+23.0%) vs. Q4 2024
New holders
208
638 more added
Sold out
128
576 more reduced

26 institutions that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 1,617 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ1 2025: $116.3B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2024.

Institutions holding VRTX in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Ashton Thomas Securities, LLC3,679$1.78M0.50%+435+13.4%Added
Nilsine Partners, LLC3,720$1.80M0.20%+516+16.1%Added
Lighthouse Financial LLC3,730$1.81M1.56%+25+0.7%Added
Prime Capital Investment Advisors, LLC3,731$1.81M0.02%+750+25.2%Added
Coastline Trust Co3,742$1.81M0.23%+225+6.4%Added
Roberts Glore & Co Inc3,743$1.81M0.55%−345−8.4%Reduced
ZWJ Investment Counsel Inc3,764$1.82M0.07%+2,100+126.2%Added
Avestar Capital, LLC3,858$1.87M0.18%+184+5.0%Added
Univest Financial Corp3,890$1.89M0.12%+3,890New
JT Stratford LLC3,912$1.90M0.34%−44−1.1%Reduced
GKV Capital Management Co., Inc.3,928$1.90M0.95%+190+5.1%Added
J. Safra Sarasin Holding AG3,946$1.91M0.03%−51,950−92.9%Reduced
Capital Investment Advisory Services, LLC3,978$1.93M0.17%−212−5.1%Reduced
SageView Advisory Group, LLC3,978$1.93M0.08%−113−2.8%Reduced
Coppell Advisory Solutions LLC3,840$1.93M0.29%+3,356+693.4%Added
STF Management LP3,999$1.94M0.93%−22−0.5%Reduced
Arjuna Capital4,000$1.94M0.54%−1,541−27.8%Reduced
Belpointe Asset Management LLC4,005$1.94M0.10%+2,784+228.0%Added
Nations Financial Group Inc,4,042$1.96M0.15%+74+1.9%Added
Jones Financial Companies LLLP3,981$1.96M0.00%+1,513+61.3%Added
MRP Capital Investments, LLC4,080$1.98M1.85%+160+4.1%Added
Texas Yale Capital Corp.4,093$1.98M0.08%00.0%Unchanged
V-Square Quantitative Management LLC4,095$1.99M0.29%−91−2.2%Reduced
S&CO Inc4,103$1.99M0.13%+4,103New
Canada Post Corp Registered Pension Plan4,104$1.99M0.88%00.0%Unchanged
Two Sigma Investments, LP4,121$2.00M0.00%−29,039−87.6%Reduced
Mather Group, LLC.4,146$2.01M0.02%+259+6.7%Added
Laffer Tengler Investments4,153$2.01M0.43%+19+0.5%Added
HighPoint Advisor Group LLC4,011$2.02M0.12%+406+11.3%Added
Woodstock Corp4,177$2.03M0.20%00.0%Unchanged
Waldron Private Wealth LLC4,196$2.03M0.10%−690−14.1%Reduced
First Citizens Bank & Trust Co4,197$2.03M0.05%−639−13.2%Reduced
Signature Wealth Management Group4,218$2.04M0.80%+143+3.5%Added
Stratos Wealth Partners, LTD.4,284$2.08M0.03%−1,097−20.4%Reduced
Oarsman Capital, Inc.4,342$2.11M0.38%+176+4.2%Added
Future Fund LLC4,349$2.11M2.71%+2,297+111.9%Added
Wedmont Private Capital4,355$2.11M0.11%+722+19.9%Added
Choate Investment Advisors4,485$2.17M0.05%+19+0.4%Added
Principal Securities, Inc.5,463$2.20M0.05%00.0%Unchanged
MUFG Securities Americas Inc.4,545$2.20M0.26%+743+19.5%Added
Trustmark National Bank Trust Department4,568$2.21M0.16%−2,209−32.6%Reduced
Strategic Advisors LLC4,580$2.22M0.43%+94+2.1%Added
Lipe & Dalton4,581$2.22M1.24%−400−8.0%Reduced
Snowden Capital Advisors LLC4,597$2.23M0.07%−143−3.0%Reduced
Callan Capital, LLC4,600$2.23M0.16%+211+4.8%Added
United Asset Strategies, Inc.4,612$2.24M0.21%+661+16.7%Added
Eqis Capital Management, Inc.4,629$2.24M0.19%−126−2.6%Reduced
Cooper Financial Group4,637$2.25M0.30%−45−1.0%Reduced
Decatur Capital Management, Inc.4,638$2.25M1.17%+10+0.2%Added
Redhawk Wealth Advisors, Inc.4,684$2.27M0.31%−655−12.3%Reduced
Integrated Wealth Concepts LLC4,714$2.29M0.03%−188−3.8%Reduced
Sectoral Asset Management Inc4,725$2.29M1.78%+1,055+28.7%Added
Nomura Holdings Inc4,734$2.30M0.01%−41,167−89.7%Reduced
Glenmede Trust Co NA4,735$2.30M0.01%−90−1.9%Reduced
Valeo Financial Advisors, LLC4,738$2.30M0.06%−1,435−23.2%Reduced
Nwam LLC4,742$2.30M0.20%−1,436−23.2%Reduced
Nemes Rush Group LLC4,746$2.30M0.29%−112−2.3%Reduced
TFR Capital, LLC.4,756$2.31M0.96%+195+4.3%Added
Oak Associates, Ltd4,771$2.31M0.17%+200+4.4%Added
Genus Capital Management Inc.4,780$2.32M0.34%+4,780New
D.A. Davidson & Co.4,805$2.33M0.02%−349−6.8%Reduced
Private Harbour Investment Management & Counsel, LLC4,825$2.34M2.60%−267−5.2%Reduced
RMR Wealth Builders4,835$2.34M0.25%+596+14.1%Added
MWA Asset Management4,925$2.39M1.66%+1,739+54.6%Added
Wimmer Associates 1, LLC5,594$2.42M1.27%−11−0.2%Reduced
Knollwood Investment Advisory, LLC4,988$2.42M0.27%00.0%Unchanged
GAMMA Investing LLC5,002$2.43M0.18%+1,005+25.1%Added
Citadel Advisors LLC5,019$2.43M0.00%−157,162−96.9%Reduced
Horizon Investments, LLC5,049$2.45M0.07%+80+1.6%Added
Boomfish Wealth Group, LLC5,051$2.45M1.59%−41−0.8%Reduced
RDA Financial Network5,058$2.45M0.73%+41+0.8%Added
Everence Capital Management Inc5,064$2.46M0.17%00.0%Unchanged
Tower View Investment Management & Research LLC5,130$2.49M1.45%−20.0%Reduced
Coldstream Capital Management Inc5,163$2.50M0.05%+267+5.5%Added
Empowered Funds, LLC5,190$2.52M0.04%−2,629−33.6%Reduced
Kestra Private Wealth Services, LLC5,259$2.55M0.04%−1,777−25.3%Reduced
3Chopt Investment Partners, LLC5,279$2.56M0.67%−442−7.7%Reduced
Perigon Wealth Management, LLC5,280$2.56M0.07%+337+6.8%Added
Summit Trail Advisors, LLC5,283$2.56M0.08%+874+19.8%Added
National Asset Management, Inc.5,314$2.58M0.08%−1,801−25.3%Reduced
APG Asset Management US Inc.5,334$2.59M0.02%00.0%Unchanged
Bangor Savings Bank5,335$2.59M0.24%−218−3.9%Reduced
Quadrant Capital Group LLC5,338$2.59M0.10%+2,841+113.8%Added
Hager Investment Management Services, LLC5,411$2.62M1.83%+27+0.5%Added
Central Pacific Bank - Trust Division5,425$2.63M0.36%+272+5.3%Added
Merit Financial Group, LLC5,427$2.63M0.04%+496+10.1%Added
Element Capital Management LLC5,448$2.64M0.66%+5,448New
EP Wealth Advisors, LLC5,449$2.64M0.02%−989−15.4%Reduced
Parallel Advisors, LLC5,450$2.64M0.06%−1,885−25.7%Reduced
Moors & Cabot, Inc.5,497$2.67M0.14%+1,894+52.6%Added
Andra AP-fonden5,500$2.67M0.04%−30,600−84.8%Reduced
Graphene Investments SAS5,500$2.67M1.95%−1,000−15.4%Reduced
Mediolanum International Funds Ltd5,428$2.67M0.04%−273−4.8%Reduced
Callan Family Office, LLC5,517$2.67M0.20%+3,067+125.2%Added
Ipswich Investment Management Co., Inc.5,518$2.68M0.66%+510+10.2%Added
Hall Laurie J Trustee5,528$2.68M0.96%+385+7.5%Added
Sovran Advisors, LLC5,489$2.68M0.35%+39+0.7%Added
Alpine Woods Capital Investors, LLC5,585$2.71M0.68%+3,255+139.7%Added
Prelude Capital Management, LLC5,632$2.73M0.28%−30−0.5%Reduced
Elefante Mark B5,661$2.74M2.17%+1,109+24.4%Added