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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
+45 vs. Q3 2024
Shares held
236.5M
+1.92M (+0.8%) vs. Q3 2024
Total value
$95.2B
−$13.7B (−12.6%) vs. Q3 2024
New holders
200
553 more added
Sold out
155
619 more reduced

33 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ4 2024: $95.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2024.

Institutions holding VRTX in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Tudor Investment Corp Et Al9,463$3.81M0.04%+9,463New
Arrowstreet Capital, Limited Partnership9,265$3.73M0.00%+9,265New
PEAK6 LLC9,120$3.67M0.14%+9,120New
Squarepoint Ops LLC9,092$3.66M0.01%+1,162+14.7%Added
Bulltick Wealth Management, LLC9,072$3.65M0.86%00.0%Unchanged
Richard Bernstein Advisors LLC9,050$3.64M0.08%00.0%Unchanged
Sigma Investment Counselors Inc9,002$3.63M0.21%+65+0.7%Added
Baldwin Brothers Inc8,997$3.62M0.25%00.0%Unchanged
Bensler, LLC8,968$3.61M0.43%−325−3.5%Reduced
Brinker Capital Investments, LLC8,963$3.61M0.04%+154+1.7%Added
Orion Portfolio Solutions, LLC8,963$3.61M0.04%+154+1.7%Added
Howe & Rusling Inc8,894$3.58M0.31%−198−2.2%Reduced
TD Waterhouse Canada Inc.8,840$3.56M0.03%+6,386+260.2%Added
Associated Banc-Corp8,828$3.56M0.11%−291−3.2%Reduced
Empirical Finance, LLC8,813$3.55M0.21%−103−1.2%Reduced
HB Wealth Management, LLC8,767$3.53M0.04%+392+4.7%Added
Commerce Bank8,638$3.48M0.02%+1,195+16.1%Added
Bleakley Financial Group, LLC8,475$3.41M0.10%+896+11.8%Added
Lockheed Martin Investment Management Co8,290$3.34M0.13%−1,660−16.7%Reduced
Paradigm Financial Partners, LLC8,269$3.33M0.42%+555+7.2%Added
Northwestern Mutual Investment Management Company, LLC8,177$3.29M0.07%−40.0%Reduced
Griffin Asset Management, Inc.8,132$3.27M0.38%−581−6.7%Reduced
Hennion & Walsh Asset Management, Inc.8,126$3.27M0.15%+554+7.3%Added
Hamilton Capital Partners Inc.8,111$3.27M0.24%−1,334−14.1%Reduced
Tokio Marine Asset Management Co Ltd8,074$3.25M0.12%+393+5.1%Added
GLOBALT Investments LLC7,988$3.22M0.12%+63+0.8%Added
Capstone Investment Advisors, LLC7,980$3.21M0.03%+7,110+817.2%Added
Transamerica Financial Advisors, Inc.7,952$3.20M0.32%−222−2.7%Reduced
Ashford Capital Management Inc7,919$3.19M0.38%00.0%Unchanged
Bokf, NA7,785$3.19M0.05%−68−0.9%Reduced
Johnson Investment Counsel Inc7,883$3.17M0.03%+63+0.8%Added
Empowered Funds, LLC7,819$3.15M0.05%−4,786−38.0%Reduced
Duncker Streett & Co Inc7,663$3.09M0.57%+335+4.6%Added
Howard Capital Management Inc.7,657$3.08M0.05%+224+3.0%Added
SFMG, LLC7,649$3.08M0.24%−96−1.2%Reduced
EagleClaw Capital Managment, LLC7,630$3.07M0.49%+5+0.1%Added
Oppenheimer & Co Inc7,629$3.07M0.05%−5,499−41.9%Reduced
Allstate Corp7,615$3.07M0.09%+7,615New
Sumitomo Life Insurance Co7,613$3.07M0.06%−115−1.5%Reduced
PKO Investment Management Joint-Stock Co7,600$3.06M0.38%+5,800+322.2%Added
Cavalier Investments, LLC7,585$3.05M1.02%+288+3.9%Added
Virtu Financial LLC7,521$3.03M0.16%+2,839+60.6%Added
Level Four Advisory Services, LLC7,467$3.01M0.12%+434+6.2%Added
Pinpoint Asset Management Ltd7,460$3.00M0.53%−800−9.7%Reduced
Linden Thomas Advisory Services, LLC7,441$3.00M0.38%+644+9.5%Added
Dakota Wealth Management7,408$2.98M0.07%−26,985−78.5%Reduced
Schonfeld Strategic Advisors LLC7,400$2.98M0.02%−63,371−89.5%Reduced
Nikko Asset Management Americas, Inc.7,379$2.97M0.03%−1,092−12.9%Reduced
Benjamin Edwards Inc7,379$2.97M0.04%+711+10.7%Added
Parallel Advisors, LLC7,335$2.95M0.07%+143+2.0%Added
Brevan Howard Capital Management LP7,270$2.93M0.07%−119−1.6%Reduced
Thompson Siegel & Walmsley LLC7,239$2.92M0.05%00.0%Unchanged
Atria Wealth Solutions, Inc.7,212$2.90M0.03%−2,523−25.9%Reduced
Private Advisor Group, LLC7,210$2.90M0.02%−34−0.5%Reduced
Algert Global LLC7,177$2.89M0.07%+7,177New
Bessemer Group Inc7,177$2.89M0.00%−7,613−51.5%Reduced
Portfolio Design Labs, LLC7,126$2.87M0.59%+2,547+55.6%Added
National Asset Management, Inc.7,115$2.87M0.09%−1,881−20.9%Reduced
Proequities, Inc.6,677$2.86M0.16%+1,786+36.5%Added
Sepio Capital, LP7,049$2.84M0.23%+18+0.3%Added
Kestra Private Wealth Services, LLC7,036$2.83M0.05%−5,825−45.3%Reduced
Parsons Capital Management Inc7,033$2.83M0.15%+1,521+27.6%Added
Chase Investment Counsel Corp6,968$2.81M0.90%−95−1.3%Reduced
Kinneret Advisory, LLC6,928$2.79M0.26%−323−4.5%Reduced
Impax Asset Management Group plc6,924$2.79M0.01%−509−6.8%Reduced
Aubrey Capital Management Ltd6,900$2.78M1.05%00.0%Unchanged
Davidson Capital Management Inc.6,896$2.78M0.73%+365+5.6%Added
Glenview Trust Co6,890$2.77M0.05%+152+2.3%Added
Winton Group Ltd6,884$2.77M0.18%−624−8.3%Reduced
Advisory Services Network, LLC6,796$2.74M0.05%−774−10.2%Reduced
Trustmark National Bank Trust Department6,777$2.73M0.20%+311+4.8%Added
Scotia Capital Inc.6,767$2.73M0.01%−573−7.8%Reduced
HM Payson & Co6,735$2.71M0.05%−340−4.8%Reduced
Fiera Capital Corp6,710$2.70M0.01%+556+9.0%Added
Plato Investment Management Ltd6,645$2.69M0.20%00.0%Unchanged
Leonteq Securities AG6,656$2.68M0.26%+2,285+52.3%Added
Savant Capital, LLC6,650$2.68M0.02%−383−5.4%Reduced
Andrew Hill Investment Advisors, Inc.6,554$2.64M1.96%−2,335−26.3%Reduced
Condor Capital Management6,528$2.63M0.23%−30−0.5%Reduced
Notis-McConarty Edward6,519$2.63M1.27%+1,257+23.9%Added
Stonegate Investment Group, LLC6,509$2.62M0.07%+41+0.6%Added
Graphene Investments SAS6,500$2.62M1.81%−600−8.5%Reduced
Delaney Dennis R6,470$2.61M1.37%+1,305+25.3%Added
Draper Asset Management, LLC6,333$2.60M1.64%+33+0.5%Added
Fidelis Capital Partners, LLC5,520$2.60M0.26%+55+1.0%Added
EP Wealth Advisors, LLC6,438$2.59M0.02%+1,285+24.9%Added
E Fund Management Co., Ltd.6,436$2.59M0.13%+1,031+19.1%Added
Joseph Group Capital Management6,422$2.59M1.02%+750+13.2%Added
Freemont Management S.A.6,400$2.58M1.26%00.0%Unchanged
J.P. Marvel Investment Advisors, LLC6,392$2.57M0.42%00.0%Unchanged
Ostrum Asset Management6,359$2.56M0.22%+1,086+20.6%Added
Leavell Investment Management, Inc.6,311$2.54M0.12%+802+14.6%Added
Harbour Capital Advisors, LLC6,242$2.54M0.57%−44−0.7%Reduced
Wedbush Securities Inc6,286$2.53M0.09%−58−0.9%Reduced
CWM, LLC6,281$2.53M0.01%−96−1.5%Reduced
Harmony Asset Management LLC6,275$2.53M1.00%−642−9.3%Reduced
Massmutual Trust Co FSB6,242$2.51M0.07%+3,641+140.0%Added
TD Private Client Wealth LLC6,217$2.50M0.07%−7,470−54.6%Reduced
Crossmark Global Holdings, Inc.6,207$2.50M0.05%+341+5.8%Added
Pinnacle Financial Partners Inc6,196$2.50M0.05%−445−6.7%Reduced