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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
+45 vs. Q3 2024
Shares held
236.5M
+1.92M (+0.8%) vs. Q3 2024
Total value
$95.2B
−$13.7B (−12.6%) vs. Q3 2024
New holders
200
553 more added
Sold out
155
619 more reduced

33 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ4 2024: $95.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2024.

Institutions holding VRTX in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Keynote Financial Services LLC1,085$436.9K0.34%+15+1.4%Added
Invesco, LLC1,091$439.3K0.17%00.0%Unchanged
Convergence Investment Partners, LLC1,095$441.0K0.10%+573+109.8%Added
Lindbrook Capital, LLC1,106$445.4K0.04%−28,526−96.3%Reduced
GPS Wealth Strategies Group, LLC1,113$448.2K0.06%−87−7.2%Reduced
Flow Traders U.S. LLC1,115$449.0K0.02%+1,115New
Wela Strategies, Inc.46,113$450.5K0.28%+46,113New
Drive Wealth Management, LLC1,121$451.3K0.11%+12+1.1%Added
Hartford Funds Management Co LLC1,121$451.4K0.04%+46+4.3%Added
Driehaus Capital Management LLC1,122$451.8K0.00%−47−4.0%Reduced
Catalyst Financial Partners LLC1,125$453.0K0.09%+39+3.6%Added
Mitchell Capital Management Co1,128$454.2K0.08%−14,325−92.7%Reduced
SevenBridge Financial Group, LLC999$454.8K0.09%00.0%Unchanged
Williams Jones Wealth Management, LLC.1,134$456.7K0.01%−1−0.1%Reduced
Sheaff Brock Investment Advisors, LLC1,138$458.3K0.04%+29+2.6%Added
Souders Financial Advisors1,147$461.9K0.06%−319−21.8%Reduced
Founders Financial Securities LLC1,147$461.9K0.04%+34+3.1%Added
Avitas Wealth Management LLC1,152$463.9K0.06%−28−2.4%Reduced
AE Wealth Management LLC1,165$469.1K0.00%+29+2.6%Added
Trust Point Inc.1,175$473.2K0.03%+59+5.3%Added
LGT Fund Management Co Ltd.1,177$474.0K0.04%−226−16.1%Reduced
DRW Securities, LLC1,189$478.8K0.03%+1,189New
Avidian Wealth Solutions, LLC1,200$483.2K0.02%+58+5.1%Added
Generali Investments Towarzystwo Funduszy Inwestycyjnych1,200$483.2K0.28%+1,200New
Aviso Financial Inc.1,203$484.4K0.02%+16+1.3%Added
Willner & Heller, LLC1,211$487.7K0.43%+137+12.8%Added
Nicholas Investment Partners, LP1,218$490.5K0.04%−35−2.8%Reduced
Custom Index Systems, LLC1,218$490.5K0.26%−16−1.3%Reduced
CoreCap Advisors, LLC1,226$493.7K0.02%−6,622−84.4%Reduced
Fifth Third Wealth Advisors LLC1,227$494.1K0.03%+230+23.1%Added
Arete Wealth Advisors, LLC1,231$496.0K0.04%+413+50.5%Added
Oversea-Chinese Banking CORP Ltd1,233$496.5K0.01%+1,233New
Spinnaker Trust1,235$497.3K0.03%+25+2.1%Added
Paces Ferry Wealth Advisors, LLC1,236$497.7K0.24%−58−4.5%Reduced
Breed's Hill Capital LLC1,236$497.8K0.26%+1,236New
Green Harvest Asset Management LLC1,237$498.1K0.01%−132−9.6%Reduced
Kovack Advisors, Inc.1,237$498.1K0.05%−20−1.6%Reduced
Total Clarity Wealth Management, Inc.1,237$498.1K0.16%−12−1.0%Reduced
Centiva Capital, LP1,257$506.2K0.02%−1,768−58.4%Reduced
Hantz Financial Services, Inc.1,258$507.0K0.01%−2,286−64.5%Reduced
Community Bank, N.A.1,260$507.4K0.07%+290+29.9%Added
Insigneo Advisory Services, LLC1,260$507.4K0.05%−54−4.1%Reduced
Platform Technology Partners1,265$509.5K0.15%−1−0.1%Reduced
Resonant Capital Advisors, LLC1,267$510.2K0.04%+41+3.3%Added
G&S Capital LLC1,267$510.2K0.21%+614+94.0%Added
Corton Capital Inc.1,278$514.7K0.30%+1,278New
Asahi Life Asset Management Co., Ltd.1,280$515.5K0.31%+1,280New
Landscape Capital Management, L.L.C.1,283$516.7K0.05%+1,283New
Advisory Alpha, LLC1,292$520.3K0.02%+117+10.0%Added
NorthCrest Asset Manangement, LLC1,293$520.8K0.02%−125−8.8%Reduced
Los Angeles Capital Management LLC1,302$524.3K0.00%−17,425−93.0%Reduced
Atlantic Union Bankshares Corp1,303$524.7K0.03%−6,255−82.8%Reduced
Sage Mountain Advisors LLC1,305$525.6K0.04%+146+12.6%Added
GeoWealth Management, LLC1,313$528.7K0.02%−1,292−49.6%Reduced
Holderness Investments Co1,316$530.0K0.12%+70+5.6%Added
Marcum Wealth, LLC1,326$534.0K0.05%+122+10.1%Added
Agf Management Ltd1,338$538.8K0.00%−1,347−50.2%Reduced
Albion Financial Group1,340$539.6K0.04%+42+3.2%Added
Vista Wealth Management Group, LLC1,347$542.4K0.03%+5+0.4%Added
Nabity-Jensen Investment Management Inc1,348$542.8K0.41%00.0%Unchanged
Fragasso Group Inc.1,350$543.6K0.04%−33−2.4%Reduced
AdvisorNet Financial, Inc1,356$546.1K0.05%+16+1.2%Added
Bourgeon Capital Management LLC1,356$546.1K0.10%+1,356New
Koshinski Asset Management, Inc.1,357$546.5K0.05%+45+3.4%Added
TKG Advisors, LLC1,247$548.2K0.25%+623+99.8%Added
Kessler Investment Group, LLC1,373$552.9K0.26%−12,397−90.0%Reduced
Clarius Group, LLC1,378$554.9K0.04%−130−8.6%Reduced
BankPlus Trust Department1,379$555.3K0.18%+1,379New
Anchor Investment Management, LLC1,406$566.2K0.05%−177−11.2%Reduced
Conning Inc.1,414$569.4K0.02%−89−5.9%Reduced
Pine Valley Investments Ltd Liability Co1,427$574.7K0.04%00.0%Unchanged
Legacy Wealth Asset Management, LLC1,451$584.3K0.16%−7−0.5%Reduced
Net Worth Advisory Group1,452$584.6K0.18%−27−1.8%Reduced
Geneos Wealth Management Inc.1,453$585.1K0.02%−244−14.4%Reduced
Rathbone Brothers plc1,454$585.5K0.00%00.0%Unchanged
SK Wealth Management, LLC1,457$586.7K0.30%00.0%Unchanged
Strategic Blueprint, LLC1,473$593.2K0.04%+386+35.5%Added
Mayflower Financial Advisors, LLC1,481$596.4K0.09%−1−0.1%Reduced
Alpha Family Trust1,485$598.0K0.34%00.0%Unchanged
Clare Market Investments LLC1,490$600.0K0.14%−140−8.6%Reduced
Private Wealth Partners, LLC1,495$602.0K0.05%−930−38.4%Reduced
SGL Investment Advisors, Inc.1,333$604.1K0.30%+12+0.9%Added
American Trust1,503$605.3K0.05%+40+2.7%Added
Belpointe Asset Management LLC1,221$605.5K0.04%−26−2.1%Reduced
SBI Securities Co., Ltd.1,511$608.5K0.02%+1,511New
Rehmann Capital Advisory Group1,516$610.5K0.04%−436−22.3%Reduced
Flagship Harbor Advisors, LLC1,522$612.9K0.03%00.0%Unchanged
Hancock Whitney Corp1,527$614.9K0.02%−1,181−43.6%Reduced
Kentucky Retirement Systems Insurance Trust Fund8,278$615.0K0.11%+636+8.3%Added
Eisler Capital Management Ltd.1,517$615.6K0.02%+1,517New
Holocene Advisors, LP1,543$621.4K0.00%+1,543New
IronOak Wealth LLC.1,546$622.6K0.70%+1,546New
Lantern Wealth Advisors, LLC1,550$624.2K0.41%+650+72.2%Added
First Manhattan Co1,555$626.2K0.00%−15−1.0%Reduced
Kensington Investment Counsel, LLC1,556$626.6K0.26%−97−5.9%Reduced
Continuum Advisory, LLC1,576$634.7K0.08%+11+0.7%Added
Perfromance Wealth Partners, LLC1,603$645.5K0.02%−13−0.8%Reduced
Eastern Bank1,620$652.4K0.01%−111−6.4%Reduced
Menard Financial Group LLC1,630$656.4K0.39%+187+13.0%Added
Sava Infond d.o.o.1,630$656.4K0.12%+1,630New