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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
+45 vs. Q3 2024
Shares held
236.5M
+1.92M (+0.8%) vs. Q3 2024
Total value
$95.2B
−$13.7B (−12.6%) vs. Q3 2024
New holders
200
553 more added
Sold out
155
619 more reduced

33 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ4 2024: $95.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2024.

Institutions holding VRTX in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
CSS LLC550$221.5K0.01%−450−45.0%Reduced
Boston Family Office LLC551$222.0K0.02%−15−2.7%Reduced
Sage Capital Advisors,llc553$222.7K0.06%00.0%Unchanged
Regent Peak Wealth Advisors LLC556$223.9K0.05%−14−2.5%Reduced
ICW Investment Advisors LLC557$224.1K0.09%+3+0.5%Added
Focus Financial Network, Inc.558$224.7K0.01%00.0%Unchanged
HBK Sorce Advisory LLC563$226.7K0.01%+32+6.0%Added
Eagle Wealth Strategies LLC565$227.5K0.16%+10+1.8%Added
Vanguard Capital Wealth Advisors565$227.5K0.25%−90−13.7%Reduced
Asset Allocation & Management Company, LLC567$228.0K0.12%+567New
Evanson Asset Management, LLC566$228.1K0.02%00.0%Unchanged
Mesirow Financial Investment Management, Inc.568$228.7K0.00%−412−42.0%Reduced
Graham Capital Management, L.P.569$229.1K0.01%+569New
Roberts Capital Advisors, LLC574$231.2K0.19%00.0%Unchanged
ICONIQ Capital, LLC574$231.2K0.00%+17+3.1%Added
Kingswood Wealth Advisors, LLC575$231.6K0.02%−3,773−86.8%Reduced
Laidlaw Wealth Management LLC575$231.6K0.10%−128−18.2%Reduced
Pure Financial Advisors, Inc.581$234.1K0.01%+21+3.8%Added
Marex Group plc582$234.4K0.00%−205−26.0%Reduced
World Equity Group, Inc.582$234.4K0.05%+582New
Geller Advisors LLC586$236.0K0.02%−1,434−71.0%Reduced
Resurgent Financial Advisors LLC586$236.0K0.14%−294−33.4%Reduced
Gibbs Wealth Management586$236.0K0.06%+586New
Icapital Wealth LLC591$238.0K0.14%00.0%Unchanged
Terry L. Blaker592$238.4K0.01%+94+18.9%Added
Ewa, LLC593$238.8K0.09%+32+5.7%Added
PKS Advisory Services, LLC595$239.6K0.07%+595New
Wintrust Investments LLC598$240.0K0.21%−28−4.5%Reduced
HMS Capital Management, LLC597$240.4K0.12%00.0%Unchanged
Sittner & Nelson, LLC598$240.8K0.10%00.0%Unchanged
Guerra Pan Advisors, LLC603$242.8K0.18%00.0%Unchanged
Monetary Management Group Inc605$243.6K0.06%−565−48.3%Reduced
Kelly Lawrence W & Associates Inc605$243.6K0.06%00.0%Unchanged
Alpha Zero LLC610$245.6K0.19%+610New
Perennial Investment Advisors, LLC613$246.9K0.03%+69+12.7%Added
First American Bank614$247.3K0.02%00.0%Unchanged
Banque Transatlantique SA612$247.8K0.01%+612New
Meridian Wealth Management, LLC619$249.3K0.01%+14+2.3%Added
One Wealth Capital Management, LLC622$250.5K0.13%+622New
MBL Wealth, LLC625$251.7K0.03%−79−11.2%Reduced
KC Investment Advisors, LLC627$252.5K0.10%−208−24.9%Reduced
Natural Investments, LLC630$253.0K0.07%+630New
Ronald Blue Trust, Inc.634$255.3K0.00%−2,077−76.6%Reduced
Thoroughbred Financial Services, LLC636$256.0K0.02%+636New
International Assets Investment Management, LLC636$258.1K0.02%−323,990−99.8%Reduced
Sanibel Captiva Trust Company, Inc.643$258.9K0.01%+110+20.6%Added
Keudell/Morrison Wealth Management646$260.1K0.07%00.0%Unchanged
Global Trust Asset Management, LLC647$260.5K0.10%−390−37.6%Reduced
Nicolet Bankshares Inc647$260.5K0.06%00.0%Unchanged
May Hill Capital, LLC648$260.9K0.10%+648New
Grimes & Company, Inc.649$261.4K0.01%+19+3.0%Added
Delta Financial Advisors LLC651$262.2K0.10%+13+2.0%Added
Smithfield Trust Co658$264.0K0.01%00.0%Unchanged
Regions Financial Corp656$264.2K0.00%−352−34.9%Reduced
Rothschild Investment LLC657$264.6K0.02%−5−0.8%Reduced
Sivia Capital Partners, LLC658$265.0K0.13%−151−18.7%Reduced
Empower Advisory Group, LLC662$266.6K0.00%+47+7.6%Added
Kornitzer Capital Management Inc665$267.8K0.01%−1,308−66.3%Reduced
Inceptionr LLC665$267.8K0.06%+665New
Everpar Advisors LLC667$268.6K0.14%−26−3.8%Reduced
StoneX Group Inc.670$269.8K0.01%+14+2.1%Added
Penserra Capital Management LLC674$270.0K0.00%+653+3,109.5%Added
Altfest L J & Co Inc671$270.2K0.03%−972−59.2%Reduced
J2 Capital Management Inc671$270.2K0.25%+671New
RFG Advisory, LLC675$271.6K0.01%−1,001−59.7%Reduced
Fox Hill Wealth Management678$273.0K0.15%−15−2.2%Reduced
William Mack & Associates, Inc.682$274.6K0.29%+682New
Onefund, LLC685$275.9K0.26%+5+0.7%Added
Pinnacle Wealth Management Advisory Group, LLC686$276.3K0.03%−25−3.5%Reduced
Seven Mile Advisory686$276.3K0.18%+9+1.3%Added
Williams & Novak, LLC687$276.7K0.27%+687New
Green Alpha Advisors, LLC689$277.5K0.22%−129−15.8%Reduced
Venture Visionary Partners LLC690$277.9K0.01%+4+0.6%Added
Empirical Financial Services, LLC d.b.a. Empirical Wealth Management691$278.3K0.01%−153−18.1%Reduced
Essex Savings Bank692$278.7K0.07%+15+2.2%Added
FourThought Financial Partners, LLC692$278.7K0.03%+692New
Washington Trust Co698$281.1K0.01%−103−12.9%Reduced
Manchester Capital Management LLC700$281.9K0.03%−31−4.2%Reduced
J.W. Cole Advisors, Inc.709$285.5K0.01%+20+2.9%Added
Bridgewater Associates, LP710$285.9K0.00%−2,742−79.4%Reduced
David Loasby703$287.9K0.03%+62+9.7%Added
Investment Advisory Group, LLC716$288.3K0.10%−2−0.3%Reduced
Simplicity Wealth,LLC718$289.1K0.06%+79+12.4%Added
Terra Nova Asset Management LLC720$289.9K0.22%−1−0.1%Reduced
Journey Strategic Wealth LLC722$290.8K0.01%−61−7.8%Reduced
Newman Dignan & Sheerar, Inc.730$294.0K0.08%−36−4.7%Reduced
Kestra Investment Management, LLC731$294.4K0.01%−1,584−68.4%Reduced
Nicholas Hoffman & Company, LLC.732$294.8K0.01%00.0%Unchanged
Wealthspire Advisors, LLC749$301.6K0.00%−43−5.4%Reduced
ASB Consultores, LLC750$302.0K0.13%−203−21.3%Reduced
Northstar Asset Management LLC750$302.0K0.07%00.0%Unchanged
Lewis Asset Management, LLC750$302.0K0.23%+750New
Virtus ETF Advisers LLC753$303.2K0.12%−1,723−69.6%Reduced
Fulton Bank, N.A.753$303.2K0.01%−45−5.6%Reduced
Financial Symmetry Inc755$304.2K0.21%00.0%Unchanged
Ausdal Financial Partners, Inc.757$304.8K0.03%+43+6.0%Added
Soltis Investment Advisors LLC762$306.8K0.03%−16−2.1%Reduced
Cynosure Management, LLC763$307.3K0.05%−130−14.6%Reduced
Loring Wolcott & Coolidge Fiduciary Advisors LLP694$308.1K0.00%+34+5.2%Added
LVW Advisors, LLC766$308.5K0.04%−26−3.3%Reduced