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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
+45 vs. Q3 2024
Shares held
236.5M
+1.92M (+0.8%) vs. Q3 2024
Total value
$95.2B
−$13.7B (−12.6%) vs. Q3 2024
New holders
200
553 more added
Sold out
155
619 more reduced

33 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ4 2024: $95.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2024.

Institutions holding VRTX in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Rosenberg Matthew Hamilton152$61.2K0.02%00.0%Unchanged
Rise Advisors, LLC153$61.6K0.03%−5−3.2%Reduced
Thematics Asset Management155$62.4K0.00%+155New
PFS Partners, LLC158$63.6K0.03%00.0%Unchanged
Colonial Trust Advisors160$64.4K0.01%00.0%Unchanged
Farmers & Merchants Investments Inc161$64.8K0.00%−6−3.6%Reduced
Oakworth Capital, Inc.167$67.3K0.00%00.0%Unchanged
Global Financial Private Client, LLC167$67.3K0.03%+1+0.6%Added
Zions Bancorporation, N.A.171$68.9K0.00%00.0%Unchanged
MCF Advisors LLC174$70.1K0.00%00.0%Unchanged
1620 Investment Advisors, Inc.178$71.6K0.05%+2+1.1%Added
Walleye Capital LLC178$71.7K0.00%−5,203−96.7%Reduced
Plante Moran Financial Advisors, LLC191$76.9K0.01%−1−0.5%Reduced
Hollencrest Capital Management195$78.5K0.00%−100−33.9%Reduced
MV Capital Management, Inc.196$78.9K0.01%+4+2.1%Added
TruNorth Capital Management, LLC200$80.5K0.02%00.0%Unchanged
Moisand Fitzgerald Tamayo, LLC200$80.5K0.01%00.0%Unchanged
Pension & Wealth Management Advisors, Inc.200$80.5K0.03%00.0%Unchanged
Legacy Bridge, LLC211$85.0K0.04%00.0%Unchanged
Crews Bank & Trust212$85.4K0.01%+212New
Asset Dedication, LLC214$86.2K0.01%+12+5.9%Added
Cary Street Partner Investment Advisory LLC225$90.6K0.06%−23,995−99.1%Reduced
Toth Financial Advisory Corp230$92.6K0.01%−1,320−85.2%Reduced
Atlantic Trust, LLC234$94.2K0.02%+97+70.8%Added
Raleigh Capital Management Inc.236$95.0K0.04%−13−5.2%Reduced
Washington Trust Advisors, Inc.239$96.2K0.01%−69−22.4%Reduced
Spectrum Wealth Counsel, LLC247$99.5K0.01%00.0%Unchanged
Riverview Trust Co255$102.7K0.09%+1+0.4%Added
Salem Investment Counselors Inc259$104.3K0.00%00.0%Unchanged
Deseret Mutual Benefit Administrators265$106.7K0.05%+45+20.5%Added
Covestor Ltd269$109.0K0.07%−415−60.7%Reduced
Roble, Belko & Company, Inc279$112.0K0.02%−63−18.4%Reduced
Hemington Wealth Management293$117.0K0.03%+6+2.1%Added
Arlington Trust Co LLC292$117.6K0.02%00.0%Unchanged
WPG Advisers, LLC294$118.4K0.11%+294New
Ritter Daniher Financial Advisory LLC297$119.6K0.03%−29−8.9%Reduced
New Harbor Financial Group, LLC300$120.8K0.04%−50−14.3%Reduced
Fiduciary Family Office, LLC300$120.8K0.04%+300New
Key Financial Inc306$123.2K0.03%+16+5.5%Added
Farmers & Merchants Trust Co of Chambersburg PA313$126.0K0.05%00.0%Unchanged
Empirical Asset Management, LLC65,763$126.4K0.04%+63,874+3,381.4%Added
Clean Yield Group315$126.9K0.04%−3−0.9%Reduced
Van Hulzen Asset Management, LLC319$128.5K0.01%+319New
TFC Financial Management323$130.1K0.02%00.0%Unchanged
Versant Capital Management, Inc330$132.9K0.03%+169+105.0%Added
Whipplewood Advisors, LLC334$134.5K0.08%+334New
Harbour Investments, Inc.342$137.7K0.00%+1+0.3%Added
Addison Advisors LLC343$138.1K0.04%+11+3.3%Added
Bartlett & Co. Wealth Management LLC357$143.8K0.00%00.0%Unchanged
Fairfield Financial Advisors, LTD360$145.0K0.05%−5−1.4%Reduced
Park Place Capital Corp365$147.0K0.04%+36+10.9%Added
Tobam364$147.0K0.04%−117−24.3%Reduced
CVA Family Office, LLC383$154.2K0.02%+35+10.1%Added
Edmond de Rothschild Holding S.A.393$158.3K0.00%−899−69.6%Reduced
LRI Investments, LLC397$160.0K0.02%−438−52.5%Reduced
Crewe Advisors LLC400$161.1K0.02%−163−29.0%Reduced
EverSource Wealth Advisors, LLC405$163.0K0.01%−28−6.5%Reduced
Stonebridge Financial Group, LLC410$165.1K0.02%+410New
Park Square Financial Group, LLC428$172.4K0.12%+428New
Adirondack Trust Co449$180.8K0.07%00.0%Unchanged
Paradigm Asset Management Co LLC450$181.2K0.05%+200+80.0%Added
Sound Income Strategies, LLC468$188.5K0.01%00.0%Unchanged
Acropolis Investment Management, LLC473$190.5K0.01%+13+2.8%Added
Grove Bank & Trust473$190.5K0.03%+63+15.4%Added
Coppell Advisory Solutions LLC484$193.3K0.03%+280+137.3%Added
Whittier Trust Co of Nevada Inc485$195.3K0.00%−91−15.8%Reduced
Montag A & Associates Inc485$195.3K0.01%−462−48.8%Reduced
Larson Financial Group LLC486$195.7K0.01%+69+16.5%Added
Quent Capital, LLC491$197.7K0.02%−49−9.1%Reduced
Revolve Wealth Partners, LLC498$200.5K0.03%−289−36.7%Reduced
UMA Financial Services, Inc.498$200.5K0.03%−32−6.0%Reduced
Nvest Financial, LLC499$200.9K0.10%00.0%Unchanged
McHugh Group, LLC500$201.3K0.15%+500New
Trust Co of Vermont502$202.2K0.01%+106+26.8%Added
Morris Financial Concepts, Inc.505$203.4K0.09%−16−3.1%Reduced
Stock Yards Bank & Trust Co505$203.4K0.01%+505New
Retireful, LLC505$203.4K0.11%+505New
US Asset Management LLC507$204.0K0.18%00.0%Unchanged
Mitchell McLeod Pugh & Williams Inc507$204.2K0.04%+507New
PUREfi Wealth, LLC511$205.8K0.20%+511New
GM Advisory Group, Inc.513$206.6K0.01%−7−1.3%Reduced
Sienna Gestion514$207.0K0.01%−20,729−97.6%Reduced
Andina Capital Management, LLC516$207.8K0.17%−28−5.1%Reduced
Quest Partners LLC517$208.2K0.03%−2,767−84.3%Reduced
Trinity Legacy Partners, LLC517$208.2K0.05%−120−18.8%Reduced
Advisor OS, LLC520$209.4K0.02%−18−3.3%Reduced
Tritonpoint Wealth, LLC521$209.8K0.02%−7−1.3%Reduced
Equitable Trust Co521$209.8K0.01%−3−0.6%Reduced
Five Oceans Advisors521$209.8K0.10%+3+0.6%Added
Abel Hall, LLC522$210.2K0.13%+40+8.3%Added
First Commonwealth Financial Corp525$211.4K0.05%+525New
BLB&B Advisors, LLC526$211.8K0.01%−1−0.2%Reduced
Moss Adams Wealth Advisors LLC531$214.0K0.02%−32−5.7%Reduced
Arlington Financial Advisors, LLC535$215.4K0.04%+35+7.0%Added
Tillman Hartley LLC536$215.8K0.06%00.0%Unchanged
Diversified Trust Co537$216.2K0.01%−491−47.8%Reduced
Kesler, Norman & Wride, LLC538$216.7K0.05%−965−64.2%Reduced
Heartwood Wealth Advisors LLC538$216.7K0.02%−6−1.1%Reduced
Clark Capital Management Group, Inc.540$217.5K0.00%−63−10.4%Reduced
Relyea Zuckerberg Hanson LLC548$220.7K0.03%−20−3.5%Reduced