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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
+45 vs. Q3 2024
Shares held
236.5M
+1.92M (+0.8%) vs. Q3 2024
Total value
$95.2B
−$13.7B (−12.6%) vs. Q3 2024
New holders
200
553 more added
Sold out
155
619 more reduced

33 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ4 2024: $95.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2024.

Institutions holding VRTX in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Swedbank AB456,587$183.9M0.23%−121,926−21.1%Reduced
Citigroup Inc462,068$186.1M0.18%−126,352−21.5%Reduced
TD Asset Management Inc469,068$188.9M0.17%−53,137−10.2%Reduced
Raymond James Financial Inc471,906$190.0M0.07%+471,906New
American Century Companies Inc473,360$190.6M0.11%−11,453−2.4%Reduced
Bellevue Group AG487,434$196.3M3.78%−83,972−14.7%Reduced
DekaBank Deutsche Girozentrale506,457$205.0M0.38%00.0%Unchanged
Pictet Asset Management Holding SA519,668$209.3M0.23%+1,665+0.3%Added
Lazard Asset Management LLC526,119$211.9M0.31%+518,132+6,487.2%Added
National Pension Service527,474$212.4M0.20%+16,427+3.2%Added
Manufacturers Life Insurance Company, The545,366$219.6M0.19%−76,859−12.4%Reduced
Natixis Advisors, L.P.557,644$224.6M0.42%+95,758+20.7%Added
Bank of Montreal581,181$234.0M0.12%+23,964+4.3%Added
BNP Paribas Arbitrage, SA596,555$240.2M0.19%+153,786+34.7%Added
Dimensional Fund Advisors LP627,517$252.7M0.06%−20,291−3.1%Reduced
Sumitomo Mitsui Trust Holdings, Inc.659,533$265.6M0.18%−12,565−1.9%Reduced
Artisan Partners Limited Partnership664,523$267.6M0.41%+114,250+20.8%Added
Wells Fargo & Company689,652$277.7M0.07%−140,568−16.9%Reduced
Voya Investment Management LLC698,706$281.3M0.29%−239,345−25.5%Reduced
Swiss National Bank729,200$293.6M0.20%−36,800−4.8%Reduced
Franklin Resources Inc760,517$306.3M0.09%+283,684+59.5%Added
Harding Loevner LP823,627$331.7M2.24%−328,998−28.5%Reduced
Assenagon Asset Management S.A.839,672$338.1M0.61%+528,029+169.4%Added
Barclays PLC843,075$339.5M0.17%−96,261−10.2%Reduced
UBS Group AG863,036$347.5M0.08%+88,821+11.5%Added
HSBC Holdings PLC873,755$351.7M0.22%+18,739+2.2%Added
California Public Employees Retirement System880,214$354.5M0.24%−87,637−9.1%Reduced
DZ BANK AG Deutsche Zentral Genossenschafts Bank, Frankfurt am Main970,662$390.9M0.42%−66,586−6.4%Reduced
Nuveen Asset Management, LLC1,051,111$423.3M0.12%+261,891+33.2%Added
WCM Investment Management, LLC1,091,522$435.9M1.03%+1,091,522New
Deutsche Bank AG1,389,605$559.6M0.22%+76,695+5.8%Added
Renaissance Technologies LLC1,397,209$562.7M0.83%−234,284−14.4%Reduced
Goldman Sachs Group Inc1,401,734$564.5M0.11%+43,200+3.2%Added
Royal Bank of Canada1,450,959$584.3M0.13%−116,677−7.4%Reduced
Charles Schwab Investment Management Inc1,663,849$670.0M0.12%+37,502+2.3%Added
Price T Rowe Associates Inc1,690,700$680.8M0.08%−77,310−4.4%Reduced
Bank of New York Mellon Corp1,759,216$708.4M0.13%−27,512−1.5%Reduced
Parnassus Investments1,815,950$731.3M1.62%+1,815,950New
Clearbridge Investments, LLC1,850,858$745.3M0.60%−121,197−6.1%Reduced
Legal & General Group Plc1,884,153$758.7M0.20%−21,159−1.1%Reduced
Invesco Ltd.1,898,457$764.5M0.14%−45,147−2.3%Reduced
Ameriprise Financial Inc2,015,523$811.6M0.21%+143,713+7.7%Added
Massachusetts Financial Services Co2,288,498$921.6M0.29%−617,207−21.2%Reduced
UBS Asset Management Americas Inc2,329,219$938.0M0.22%−112,249−4.6%Reduced
Bank of America Corp2,419,353$974.3M0.09%−189,604−7.3%Reduced
Northern Trust Corp2,721,049$1.10B0.16%+355,057+15.0%Added
Janus Henderson Group PLC2,833,889$1.14B0.58%+317,058+12.6%Added
Edgewood Management LLC2,956,608$1.19B3.42%+1,410,238+91.2%Added
Morgan Stanley3,171,387$1.28B0.09%+132,950+4.4%Added
Amundi3,281,205$1.35B0.47%−478,031−12.7%Reduced
Norges Bank3,414,324$1.37B0.18%+4,542+0.1%Added
Loomis Sayles & Co L P3,772,789$1.52B1.92%+704,575+23.0%Added
Alliancebernstein L.P.3,920,020$1.58B0.54%−3,452,747−46.8%Reduced
Jennison Associates LLC4,317,762$1.74B1.06%−1,232,624−22.2%Reduced
Geode Capital Management, LLC5,648,236$2.27B0.18%−287,652−4.8%Reduced
Wellington Management Group LLP5,916,084$2.38B0.44%+1,117,214+23.3%Added
JPMorgan Chase & Co6,313,107$2.54B0.20%−615,480−8.9%Reduced
FMR LLC9,219,046$3.71B0.22%−1,305,967−12.4%Reduced
Capital Research Global Investors10,428,951$4.20B0.86%+1,426,746+15.8%Added
State Street Corp11,979,405$4.82B0.19%+163,156+1.4%Added
BlackRock, Inc.21,825,470$8.79B0.18%+37,924+0.2%Added
Vanguard Group Inc23,258,288$9.37B0.16%+98,654+0.4%Added
Capital World Investors28,325,695$11.4B1.73%+1,514,993+5.7%Added
Perpetual Ltd0$00.00%−167,221−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−131,156−100.0%Sold out
Antipodes Partners Ltd0$00.00%−127,853−100.0%Sold out
Egerton Capital (UK) LLP0$00.00%−124,045−100.0%Sold out
Walleye Trading LLC0$00.00%−42,490−100.0%Sold out
First Turn Management, LLC0$00.00%−35,222−100.0%Sold out
Telemark Asset Management, LLC0$00.00%−25,000−100.0%Sold out
MUFG Securities EMEA plc0$00.00%−21,000−100.0%Sold out
Unisphere Establishment0$00.00%−20,800−100.0%Sold out
Steel Peak Wealth Management LLC0$00.00%−20,163−100.0%Sold out
Bronte Capital Management Pty Ltd.0$00.00%−19,856−100.0%Sold out
Artia Global Partners LP0$00.00%−18,900−100.0%Sold out
Achmea Investment Management B.V.0$00.00%−15,934−100.0%Sold out
BNC Wealth Management, LLC0$00.00%−13,356−100.0%Sold out
Ibex Wealth Advisors0$00.00%−62,298−100.0%Sold out
Asio Capital, LLC0$00.00%−11,128−100.0%Sold out
NWK Group, Inc.0$00.00%−10,903−100.0%Sold out
Siemens Fonds Invest GmbH0$00.00%−12,567−100.0%Sold out
FORA Capital, LLC0$00.00%−9,402−100.0%Sold out
Nkcfo LLC0$00.00%−8,243−100.0%Sold out
Signet Financial Management, LLC0$00.00%−8,163−100.0%Sold out
Headlands Technologies LLC0$00.00%−7,357−100.0%Sold out
Wisconsin Capital Management LLC0$00.00%−7,121−100.0%Sold out
Next Century Growth Investors LLC0$00.00%−6,740−100.0%Sold out
Marvin & Palmer Associates Inc0$00.00%−6,467−100.0%Sold out
Highland Capital Management, LLC0$00.00%−6,236−100.0%Sold out
Veriti Management LLC0$00.00%−5,868−100.0%Sold out
Pegasus Asset Management, Inc.0$00.00%−5,670−100.0%Sold out
Lake Street Financial LLC0$00.00%−5,185−100.0%Sold out
Pinnacle Wealth Management, LLC0$00.00%−4,783−100.0%Sold out
New England Research & Management, Inc.0$00.00%−4,575−100.0%Sold out
Lighthouse Investment Partners, LLC0$00.00%−4,500−100.0%Sold out
TriaGen Wealth Management LLC0$00.00%−4,468−100.0%Sold out
Vivid Wealth Management, LLC0$00.00%−4,352−100.0%Sold out
Connective Portfolio Management, LLC0$00.00%−13,110−100.0%Sold out
Two Sigma Securities, LLC0$00.00%−4,205−100.0%Sold out
Torno Capital, LLC0$00.00%−4,000−100.0%Sold out