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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 1 sale; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
+45 vs. Q3 2024
Shares held
236.5M
+1.92M (+0.8%) vs. Q3 2024
Total value
$95.2B
−$13.7B (−12.6%) vs. Q3 2024
New holders
200
553 more added
Sold out
155
619 more reduced

33 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ4 2024: $95.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2024.

Institutions holding VRTX in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
USS Investment Management Ltd44,403$17.9M0.13%−2,996−6.3%Reduced
Atalanta Sosnoff Capital, LLC45,202$18.2M0.40%−74,236−62.2%Reduced
Calamos Advisors LLC45,244$18.2M0.08%00.0%Unchanged
Braun Stacey Associates Inc45,450$18.3M0.68%−6,047−11.7%Reduced
Churchill Management Corp45,457$18.3M0.20%+102+0.2%Added
Mackenzie Financial Corp45,632$18.4M0.03%−23,060−33.6%Reduced
Sumitomo Mitsui DS Asset Management Company, Ltd45,669$18.4M0.19%+2,036+4.7%Added
State of Alaska, Department of Revenue45,785$18.4M0.21%−2,190−4.6%Reduced
Nomura Holdings Inc45,901$18.5M0.10%+5,868+14.7%Added
CIBC World Markets Corp46,339$18.7M0.11%+5,665+13.9%Added
Castleark Management LLC46,485$18.7M0.65%−36,240−43.8%Reduced
Varma Mutual Pension Insurance Co46,826$18.9M0.14%−9,100−16.3%Reduced
Bank of Nova Scotia47,097$19.0M0.03%−27,573−36.9%Reduced
Cumberland Partners Ltd47,326$19.1M1.33%+4,126+9.6%Added
Illinois Municipal Retirement Fund47,388$19.1M0.27%−16,391−25.7%Reduced
Sanctuary Advisors, LLC43,831$19.2M0.12%+928+2.2%Added
Banco Santander, S.A.48,184$19.4M0.23%+32,316+203.7%Added
Xponance, Inc.48,507$19.5M0.18%+539+1.1%Added
HighTower Advisors, LLC48,586$19.6M0.03%−8,656−15.1%Reduced
IFM Investors Pty Ltd48,731$19.6M0.20%−4,691−8.8%Reduced
De Burlo Group Inc48,735$19.6M2.62%−460−0.9%Reduced
Hemenway Trust Co LLC49,413$19.9M1.61%+9,294+23.2%Added
Comerica Bank49,578$20.0M0.08%−4,045−7.5%Reduced
Rhenman & Partners Asset Management AB50,000$20.1M2.07%+2,250+4.7%Added
Boston Common Asset Management, LLC50,292$20.3M0.59%+26+0.1%Added
Hallmark Capital Management Inc50,524$20.3M1.52%+50+0.1%Added
Martingale Asset Management L P51,207$20.6M0.50%−2,120−4.0%Reduced
Aristotle Atlantic Partners, LLC51,251$20.6M0.65%−2,843−5.3%Reduced
Zurich Insurance Group Ltd51,527$20.7M0.17%−1,735−3.3%Reduced
Reynders McVeigh Capital Management, LLC52,254$21.0M1.11%+3,524+7.2%Added
Barlow Wealth Partners, Inc.49,710$21.1M2.67%+2,138+4.5%Added
China Universal Asset Management Co., Ltd.52,381$21.1M1.97%+2,962+6.0%Added
Vestcor Inc52,631$21.2M0.70%−12,624−19.3%Reduced
Zacks Investment Management52,653$21.2M0.20%−9,831−15.7%Reduced
Amalgamated Bank53,004$21.3M0.18%−3,186−5.7%Reduced
Cullinan Associates Inc53,162$21.4M1.37%−1,500−2.7%Reduced
Federation des caisses Desjardins du Quebec53,236$21.4M0.11%+13,749+34.8%Added
Cetera Investment Advisers53,957$21.7M0.05%+328+0.6%Added
Shelton Capital Management54,631$22.0M0.55%+647+1.2%Added
Commonwealth of Pennsylvania Public School Empls Retrmt Sys54,758$22.1M0.14%−1,428−2.5%Reduced
Twinbeech Capital LP55,249$22.2M0.38%+55,249New
Atwood & Palmer Inc55,390$22.3M1.53%+1,130+2.1%Added
Retirement Systems of Alabama55,758$22.5M0.08%−166,947−75.0%Reduced
Czech National Bank55,838$22.5M0.21%+3,260+6.2%Added
J. Safra Sarasin Holding AG55,896$22.5M0.38%−4,246−7.1%Reduced
Segall Bryant & Hamill, LLC56,235$22.6M0.31%−1,590−2.7%Reduced
Polar Asset Management Partners Inc.57,000$23.0M0.34%+57,000New
Edgemoor Investment Advisors, Inc.57,097$23.0M2.03%+92+0.2%Added
Moody Lynn & Lieberson, LLC57,223$23.0M1.41%−7,984−12.2%Reduced
Forsta Ap-Fonden58,700$23.6M0.17%−1,200−2.0%Reduced
Nissay Asset Management Corp58,242$23.8M0.15%+2,879+5.2%Added
GF Fund Management Co. Ltd.59,178$23.8M0.52%+59,178New
La Banque Postale Asset Management SA59,359$23.9M0.32%+54,646+1,159.5%Added
Foster Dykema Cabot & Partners, LLC60,864$24.5M1.91%+1,094+1.8%Added
Davidson Investment Advisors61,161$24.6M1.20%+12,631+26.0%Added
Teachers Retirement System of the State of Kentucky63,057$25.4M0.22%−33,779−34.9%Reduced
Commonwealth Equity Services, LLC64,120$25.8M0.04%+693+1.1%Added
Ossiam64,833$26.1M0.45%+435+0.7%Added
Daiwa Securities Group Inc.65,728$26.5M0.12%+7,861+13.6%Added
Gateway Investment Advisers LLC65,842$26.5M0.30%−719−1.1%Reduced
Erste Asset Management GmbH65,774$26.5M0.33%+2,260+3.6%Added
C WorldWide Group Holding A/S67,557$27.2M0.33%00.0%Unchanged
AMF Pensionsforsakring AB67,757$27.3M0.19%−100,161−59.6%Reduced
Fjarde Ap-Fonden /Fourth Swedish National Pension Fund68,088$27.4M0.28%−3,900−5.4%Reduced
Voloridge Investment Management, LLC69,712$28.1M0.10%−67,376−49.1%Reduced
Nisa Investment Advisors, LLC70,222$28.3M0.11%−5,128−6.8%Reduced
Healthcare of Ontario Pension Plan Trust Fund72,209$29.1M0.06%+23,144+47.2%Added
State of Michigan Retirement System72,423$29.2M0.15%−1,200−1.6%Reduced
MetLife Investment Management73,884$29.8M0.16%+873+1.2%Added
Arizona State Retirement System74,607$30.0M0.18%+673+0.9%Added
William Blair Investment Management, LLC77,532$31.2M0.08%+983+1.3%Added
Alyeska Investment Group, L.P.77,535$31.2M0.12%+74,182+2,212.4%Added
Jupiter Asset Management Ltd78,166$31.5M0.31%−81,761−51.1%Reduced
STRS Ohio78,531$31.6M0.13%−9,807−11.1%Reduced
The PNC Financial Services Group, Inc.78,622$31.7M0.02%−807−1.0%Reduced
Beacon Investment Advisory Services, Inc.78,824$31.7M1.38%−347−0.4%Reduced
Creative Planning79,470$32.0M0.03%−997−1.2%Reduced
GuoLine Advisory Pte Ltd79,700$32.1M3.31%00.0%Unchanged
Assetmark, Inc79,865$32.2M0.09%−124,206−60.9%Reduced
Wealth Enhancement Advisory Services, LLC80,189$32.3M0.06%−21,702−21.3%Reduced
B. Metzler seel. Sohn & Co. AG80,759$32.4M0.33%+40,766+101.9%Added
Country Trust Bank83,602$33.7M0.84%−10,489−11.1%Reduced
CIBC Asset Management Inc84,491$34.0M0.11%+4,389+5.5%Added
Resona Asset Management Co.,Ltd.86,227$34.8M0.21%−7,976−8.5%Reduced
Epoch Investment Partners, Inc.86,477$34.8M0.17%−8,104−8.6%Reduced
KLP Kapitalforvaltning AS86,941$35.0M0.17%+86,941New
Banco Bilbao Vizcaya Argentaria, S.A.87,796$35.4M0.37%−4,531−4.9%Reduced
Corebridge Financial, Inc.88,046$35.5M0.19%+112+0.1%Added
Thrivent Financial for Lutherans87,900$35.6M0.07%−3,775−4.1%Reduced
Man Group plc88,726$35.7M0.11%+37,008+71.6%Added
Rafferty Asset Management, LLC90,219$36.3M0.13%+3,910+4.5%Added
Janney Montgomery Scott LLC92,192$37.1M0.10%−35,233−27.6%Reduced
State of Tennessee, Treasury Department93,189$37.5M0.14%−7,333−7.3%Reduced
FIL Ltd93,273$37.6M0.04%+86,242+1,226.6%Added
LMR Partners LLP93,801$37.8M0.66%+93,801New
State of New Jersey Common Pension Fund D95,267$38.4M0.15%00.0%Unchanged
Credit Agricole S A96,715$38.9M0.13%−1,792−1.8%Reduced
Allspring Global Investments Holdings, LLC96,626$39.2M0.06%−139,700−59.1%Reduced
Rockefeller Capital Management L.P.98,789$39.8M0.10%+28,240+40.0%Added
Teacher Retirement System of Texas104,895$42.2M0.15%+22,165+26.8%Added