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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 2 sales; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
+45 vs. Q3 2024
Shares held
236.5M
+1.92M (+0.8%) vs. Q3 2024
Total value
$95.2B
−$13.7B (−12.6%) vs. Q3 2024
New holders
200
553 more added
Sold out
155
619 more reduced

33 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ4 2024: $95.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2024.

Institutions holding VRTX in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Sterling Capital Management LLC11,999$4.83M0.07%−291−2.4%Reduced
Banque Pictet & Cie SA12,043$4.85M0.05%+788+7.0%Added
Captrust Financial Advisors12,048$4.85M0.01%−2,361−16.4%Reduced
EFG Asset Management (North America) Corp.12,055$4.86M0.66%+3,964+49.0%Added
Keybank National Association12,118$4.88M0.02%+147+1.2%Added
Americana Partners, LLC12,145$4.89M0.20%+897+8.0%Added
Apollon Wealth Management, LLC12,172$4.90M0.11%+3,976+48.5%Added
Chicago Capital, LLC12,218$4.92M0.13%−74−0.6%Reduced
First National Bank of Mount Dora, Trust Investment Services12,231$4.93M1.15%+352+3.0%Added
Kayne Anderson Rudnick Investment Management LLC12,274$4.94M0.01%−827−6.3%Reduced
New Mexico Educational Retirement Board12,300$4.95M0.17%−300−2.4%Reduced
Te Ahumairangi Investment Management Ltd12,413$5.00M1.04%−926−6.9%Reduced
Northwestern Mutual Wealth Management Co12,547$5.05M0.00%+150+1.2%Added
Baldwin Investment Management, LLC12,559$5.06M0.66%+668+5.6%Added
Cambridge Investment Research Advisors, Inc.12,581$5.07M0.02%−1,936−13.3%Reduced
Covenant Asset Management, LLC12,627$5.08M1.13%−137−1.1%Reduced
GWM Advisors LLC12,651$5.09M0.03%+1,294+11.4%Added
Impact Asset Management GmbH12,890$5.19M2.05%−65−0.5%Reduced
Sequoia Financial Advisors, LLC12,890$5.19M0.05%+602+4.9%Added
Pinnacle Associates Ltd12,896$5.19M0.07%+6,857+113.5%Added
Sivik Global Healthcare LLC13,000$5.24M2.89%+3,000+30.0%Added
Cornerstone Advisors, LLC13,000$5.24M0.21%00.0%Unchanged
Fiduciary Trust Co13,160$5.30M0.07%+1,147+9.5%Added
Wiley Bros.-Aintree Capital, LLC13,072$5.33M0.06%+6,948+113.5%Added
Voleon Capital Management LP13,228$5.33M0.40%+13,228New
Meiji Yasuda Asset Management Co Ltd.13,263$5.34M0.20%+193+1.5%Added
New Age Alpha Advisors, LLC13,307$5.36M0.22%+13,307New
Motley Fool Asset Management LLC13,484$5.43M0.28%+1,840+15.8%Added
Omers Administration Corp13,742$5.53M0.05%−1,213−8.1%Reduced
Securian Asset Management, Inc13,809$5.56M0.16%−435−3.1%Reduced
Metis Global Partners, LLC13,885$5.59M0.17%+430+3.2%Added
Maryland State Retirement & Pension System13,932$5.61M0.12%−980−6.6%Reduced
Knuff & Co LLC13,941$5.61M1.71%−252−1.8%Reduced
Norinchukin Bank, The13,957$5.62M0.12%+1,106+8.6%Added
Trifecta Capital Advisors, LLC13,965$5.62M1.11%+430+3.2%Added
Jefferies Financial Group Inc.13,984$5.63M0.06%−18,659−57.2%Reduced
Mercer Global Advisors Inc14,008$5.64M0.01%−1,543−9.9%Reduced
Puzo Michael J14,109$5.68M1.59%+1,872+15.3%Added
Advisors Capital Management, LLC14,246$5.74M0.09%−295−2.0%Reduced
Fisher Funds Management LTD14,331$5.77M0.14%+14,331New
Pinebridge Investments, L.P.14,448$5.82M0.04%−39,692−73.3%Reduced
Park Avenue Securities LLC14,454$5.82M0.06%+467+3.3%Added
Madison Asset Management, LLC14,522$5.85M0.07%+11+0.1%Added
Madison Investment Advisors, LLC14,522$5.85M0.07%+14,522New
Jane Street Group, LLC14,554$5.86M0.01%−39,638−73.1%Reduced
Procyon Private Wealth Partners, LLC14,635$5.89M0.38%−375−2.5%Reduced
Shell Asset Management Co14,657$5.90M0.26%+79+0.5%Added
Harvest Fund Management Co., Ltd15,225$6.08M0.28%+3,307+27.7%Added
Princeton Global Asset Management LLC15,132$6.09M1.14%−74−0.5%Reduced
Boston Private Wealth LLC15,163$6.11M0.11%+15,163New
Princeton Capital Management LLC15,174$6.11M1.89%+64+0.4%Added
CIBC World Markets Inc.15,473$6.23M0.01%+2,404+18.4%Added
Fulcrum Capital LLC15,494$6.24M1.31%+108+0.7%Added
Wealth High Governance Capital Ltda15,528$6.25M2.24%+15,528New
Ameritas Investment Partners, Inc.15,902$6.40M0.21%+162+1.0%Added
Hartford Investment Management Co15,921$6.41M0.21%−329−2.0%Reduced
Nia Impact Advisors, LLC15,932$6.42M2.09%−1,395−8.1%Reduced
Torray LLC16,008$6.45M0.92%+257+1.6%Added
Cresset Asset Management, LLC16,018$6.45M0.03%−8,025−33.4%Reduced
Beacon Pointe Advisors, LLC16,203$6.52M0.07%−793−4.7%Reduced
Kestra Advisory Services, LLC16,258$6.55M0.04%−513−3.1%Reduced
UniSuper Management Pty Ltd16,274$6.55M0.05%+4,017+32.8%Added
BI Asset Management Fondsmaeglerselskab A/S16,321$6.57M0.07%−3,503−17.7%Reduced
Baird Financial Group, Inc.16,371$6.59M0.01%−6,797−29.3%Reduced
First American Trust, FSB16,497$6.64M0.66%−20−0.1%Reduced
QRG Capital Management, Inc.16,562$6.67M0.07%−1,780−9.7%Reduced
Janney Capital Management LLC16,589$6.68M0.44%−566−3.3%Reduced
Broderick Brian C16,874$6.80M1.33%+5,414+47.2%Added
Broadleaf Partners, LLC16,923$6.81M1.59%−201−1.2%Reduced
Trillium Asset Management, LLC16,962$6.83M0.18%−1,122−6.2%Reduced
Grandfield & Dodd, LLC16,964$6.83M0.42%+2,820+19.9%Added
TownSquare Capital, LLC17,127$6.90M0.08%+2,073+13.8%Added
Kovitz Investment Group Partners, LLC17,181$6.92M0.03%−18,902−52.4%Reduced
Investment Management Corp of Ontario17,297$6.97M0.23%−6,288−26.7%Reduced
Silvercrest Asset Management Group LLC17,348$6.99M0.05%+3,410+24.5%Added
Telos Capital Management, Inc.17,627$7.10M0.76%+1,605+10.0%Added
Gabelli Funds LLC17,674$7.12M0.05%+275+1.6%Added
Kentucky Retirement Systems17,736$7.14M0.21%−245−1.4%Reduced
Oddo BHF Asset Management SAS17,773$7.16M0.36%+760+4.5%Added
Bamco Inc18,000$7.25M0.02%−5,000−21.7%Reduced
Wolverine Trading, LLC18,168$7.26M0.16%+9,502+109.6%Added
Liontrust Investment Partners LLP18,029$7.26M0.11%+2,029+12.7%Added
Ieq Capital, LLC18,223$7.34M0.07%−4,358−19.3%Reduced
Toroso Investments, LLC18,353$7.39M0.06%+6,672+57.1%Added
Greenwood Capital Associates LLC18,465$7.44M0.97%−2,059−10.0%Reduced
Spire Wealth Management18,504$7.45M0.23%−219−1.2%Reduced
M&T Bank Corp18,526$7.46M0.03%−341−1.8%Reduced
Atria Investments LLC18,598$7.49M0.09%−1,527−7.6%Reduced
Heirloom Wealth Management18,793$7.57M2.27%+1,185+6.7%Added
Verition Fund Management LLC18,830$7.58M0.04%+5,730+43.7%Added
HealthInvest Partners AB22,257$7.60M3.60%+5,264+31.0%Added
Lombard Odier Asset Management (Europe) Ltd18,973$7.64M0.49%−1,261−6.2%Reduced
Envestnet Portfolio Solutions, Inc.19,249$7.75M0.03%−17,777−48.0%Reduced
Gulf International Bank (UK) Ltd19,432$7.83M0.20%−916−4.5%Reduced
Vident Advisory, LLC19,834$7.99M0.14%+11,476+137.3%Added
NBW Capital LLC20,238$8.15M1.51%−351−1.7%Reduced
Cyrus J. Lawrence, LLC20,384$8.21M1.59%−6,313−23.6%Reduced
Somerville Kurt F20,392$8.21M1.38%+3,748+22.5%Added
Oppenheimer Asset Management Inc.20,528$8.27M0.10%−2,862−12.2%Reduced
Great Valley Advisor Group, Inc.20,593$8.29M0.19%+2,343+12.8%Added