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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 2 sales; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2024

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,563
+45 vs. Q3 2024
Shares held
236.5M
+1.92M (+0.8%) vs. Q3 2024
Total value
$95.2B
−$13.7B (−12.6%) vs. Q3 2024
New holders
200
553 more added
Sold out
155
619 more reduced

33 institutions that held it in Q3 2024 haven't filed for Q4 2024 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 1,563 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ4 2024: $95.2B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2024.

Institutions holding VRTX in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Chase Investment Counsel Corp6,968$2.81M0.90%−95−1.3%Reduced
Parsons Capital Management Inc7,033$2.83M0.15%+1,521+27.6%Added
Kestra Private Wealth Services, LLC7,036$2.83M0.05%−5,825−45.3%Reduced
Sepio Capital, LP7,049$2.84M0.23%+18+0.3%Added
Proequities, Inc.6,677$2.86M0.16%+1,786+36.5%Added
National Asset Management, Inc.7,115$2.87M0.09%−1,881−20.9%Reduced
Portfolio Design Labs, LLC7,126$2.87M0.59%+2,547+55.6%Added
Bessemer Group Inc7,177$2.89M0.00%−7,613−51.5%Reduced
Algert Global LLC7,177$2.89M0.07%+7,177New
Private Advisor Group, LLC7,210$2.90M0.02%−34−0.5%Reduced
Atria Wealth Solutions, Inc.7,212$2.90M0.03%−2,523−25.9%Reduced
Thompson Siegel & Walmsley LLC7,239$2.92M0.05%00.0%Unchanged
Brevan Howard Capital Management LP7,270$2.93M0.07%−119−1.6%Reduced
Parallel Advisors, LLC7,335$2.95M0.07%+143+2.0%Added
Benjamin Edwards Inc7,379$2.97M0.04%+711+10.7%Added
Nikko Asset Management Americas, Inc.7,379$2.97M0.03%−1,092−12.9%Reduced
Schonfeld Strategic Advisors LLC7,400$2.98M0.02%−63,371−89.5%Reduced
Dakota Wealth Management7,408$2.98M0.07%−26,985−78.5%Reduced
Linden Thomas Advisory Services, LLC7,441$3.00M0.38%+644+9.5%Added
Pinpoint Asset Management Ltd7,460$3.00M0.53%−800−9.7%Reduced
Level Four Advisory Services, LLC7,467$3.01M0.12%+434+6.2%Added
Virtu Financial LLC7,521$3.03M0.16%+2,839+60.6%Added
Cavalier Investments, LLC7,585$3.05M1.02%+288+3.9%Added
PKO Investment Management Joint-Stock Co7,600$3.06M0.38%+5,800+322.2%Added
Sumitomo Life Insurance Co7,613$3.07M0.06%−115−1.5%Reduced
Allstate Corp7,615$3.07M0.09%+7,615New
Oppenheimer & Co Inc7,629$3.07M0.05%−5,499−41.9%Reduced
EagleClaw Capital Managment, LLC7,630$3.07M0.49%+5+0.1%Added
SFMG, LLC7,649$3.08M0.24%−96−1.2%Reduced
Howard Capital Management Inc.7,657$3.08M0.05%+224+3.0%Added
Duncker Streett & Co Inc7,663$3.09M0.57%+335+4.6%Added
Empowered Funds, LLC7,819$3.15M0.05%−4,786−38.0%Reduced
Johnson Investment Counsel Inc7,883$3.17M0.03%+63+0.8%Added
Bokf, NA7,785$3.19M0.05%−68−0.9%Reduced
Ashford Capital Management Inc7,919$3.19M0.38%00.0%Unchanged
Transamerica Financial Advisors, Inc.7,952$3.20M0.32%−222−2.7%Reduced
Capstone Investment Advisors, LLC7,980$3.21M0.03%+7,110+817.2%Added
GLOBALT Investments LLC7,988$3.22M0.12%+63+0.8%Added
Tokio Marine Asset Management Co Ltd8,074$3.25M0.12%+393+5.1%Added
Hamilton Capital Partners Inc.8,111$3.27M0.24%−1,334−14.1%Reduced
Hennion & Walsh Asset Management, Inc.8,126$3.27M0.15%+554+7.3%Added
Griffin Asset Management, Inc.8,132$3.27M0.38%−581−6.7%Reduced
Northwestern Mutual Investment Management Company, LLC8,177$3.29M0.07%−40.0%Reduced
Paradigm Financial Partners, LLC8,269$3.33M0.42%+555+7.2%Added
Lockheed Martin Investment Management Co8,290$3.34M0.13%−1,660−16.7%Reduced
Bleakley Financial Group, LLC8,475$3.41M0.10%+896+11.8%Added
Commerce Bank8,638$3.48M0.02%+1,195+16.1%Added
HB Wealth Management, LLC8,767$3.53M0.04%+392+4.7%Added
Empirical Finance, LLC8,813$3.55M0.21%−103−1.2%Reduced
Associated Banc-Corp8,828$3.56M0.11%−291−3.2%Reduced
TD Waterhouse Canada Inc.8,840$3.56M0.03%+6,386+260.2%Added
Howe & Rusling Inc8,894$3.58M0.31%−198−2.2%Reduced
Brinker Capital Investments, LLC8,963$3.61M0.04%+154+1.7%Added
Orion Portfolio Solutions, LLC8,963$3.61M0.04%+154+1.7%Added
Bensler, LLC8,968$3.61M0.43%−325−3.5%Reduced
Baldwin Brothers Inc8,997$3.62M0.25%00.0%Unchanged
Sigma Investment Counselors Inc9,002$3.63M0.21%+65+0.7%Added
Richard Bernstein Advisors LLC9,050$3.64M0.08%00.0%Unchanged
Bulltick Wealth Management, LLC9,072$3.65M0.86%00.0%Unchanged
Squarepoint Ops LLC9,092$3.66M0.01%+1,162+14.7%Added
PEAK6 LLC9,120$3.67M0.14%+9,120New
Arrowstreet Capital, Limited Partnership9,265$3.73M0.00%+9,265New
Tudor Investment Corp Et Al9,463$3.81M0.04%+9,463New
BW Gestao de Investimentos Ltda.9,472$3.81M0.18%+9,472New
Catalyst Capital Advisors LLC9,545$3.84M0.08%−225−2.3%Reduced
Compagnie Lombard Odier SCmA9,565$3.85M0.06%−864−8.3%Reduced
Vestor Capital, LLC9,736$3.92M0.30%+9,374+2,589.5%Added
Baker Chad R9,740$3.92M0.77%00.0%Unchanged
Central Trust Co9,791$3.94M0.10%−196−2.0%Reduced
Montchanin Asset Management, LLC9,802$3.95M3.83%−1,620−14.2%Reduced
PDT Partners, LLC9,803$3.95M0.35%+9,803New
Shorepoint Capital Partners LLC9,810$3.95M0.90%+280+2.9%Added
Diversify Wealth Management, LLC9,773$4.00M0.31%+6,027+160.9%Added
Hudson Bay Capital Management LP10,015$4.03M0.02%−19,985−66.6%Reduced
HRT Financial LP10,030$4.04M0.02%−33,267−76.8%Reduced
GAM Holding AG10,057$4.05M0.30%−234−2.3%Reduced
Patton Fund Management, Inc.10,084$4.06M0.80%−1,515−13.1%Reduced
Kidder Stephen W10,248$4.13M1.24%+2,544+33.0%Added
Fayez Sarofim & Co10,392$4.18M0.01%+10,392New
Morse Asset Management, Inc10,555$4.25M0.97%+578+5.8%Added
Ascent Group, LLC10,787$4.34M0.33%−9−0.1%Reduced
Tema ETFs LLC10,981$4.42M1.84%+10,981New
BTC Capital Management, Inc.11,030$4.43M0.41%+557+5.3%Added
Generali Investments CEE, investicni spolecnost, a.s.11,030$4.44M0.46%+11,030New
Readystate Asset Management LP11,058$4.45M0.19%+4,904+79.7%Added
Mark Sheptoff Financial Planning, LLC11,071$4.46M2.39%−175−1.6%Reduced
Synovus Financial Corp11,154$4.49M0.06%−50.0%Reduced
Mirabella Financial Services LLP11,184$4.50M0.41%+11,184New
Parallax Volatility Advisers, L.P.11,263$4.54M0.10%+3,769+50.3%Added
United Capital Financial Advisers, LLC11,364$4.58M0.04%−21−0.2%Reduced
Navellier & Associates Inc11,427$4.60M0.55%+395+3.6%Added
Avantax Advisory Services, Inc.11,471$4.62M0.03%−1,037−8.3%Reduced
Engineers Gate Manager LP11,599$4.67M0.08%+11,599New
Slow Capital, Inc.11,636$4.69M0.66%−1,003−7.9%Reduced
Triasima Portfolio Management inc.11,660$4.70M0.91%+127+1.1%Added
Northwest Bancshares, Inc.11,721$4.72M0.87%−1,404−10.7%Reduced
E. Ohman J:or Asset Management AB11,740$4.73M0.11%+1,430+13.9%Added
Codex Capital Asset Management L.L.C.11,750$4.73M2.14%00.0%Unchanged
Cutter & CO Brokerage, Inc.11,762$4.74M1.16%+220+1.9%Added
Forte Capital LLC11,957$4.82M0.54%−244−2.0%Reduced