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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2022

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,224
+121 vs. Q3 2022
Shares held
237.1M
+549.4K (+0.2%) vs. Q3 2022
Total value
$68.3B
−$59.7M (−0.1%) vs. Q3 2022
New holders
185
438 more added
Sold out
64
440 more reduced

24 institutions that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 1,224 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ4 2022: $68.3B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2022.

Institutions holding VRTX in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Bank of New York Mellon Corp2,082,299$601.3M0.14%+8290.0%Added
Amundi2,130,197$622.5M0.34%+304,875+16.7%Added
Renaissance Technologies LLC2,246,752$648.8M0.89%+107,867+5.0%Added
Norges Bank2,451,521$708.0M0.17%+163,049+7.1%Added
Bank of America Corp2,497,060$721.1M0.09%−30,395−1.2%Reduced
Morgan Stanley2,578,444$744.6M0.08%+640,899+33.1%Added
Northern Trust Corp2,851,559$823.5M0.17%−36,439−1.3%Reduced
UBS Asset Management Americas Inc2,929,416$846.0M0.44%−229,276−7.3%Reduced
Clearbridge Investments, LLC3,486,120$1.01B0.99%−414,736−10.6%Reduced
Ameriprise Financial Inc3,578,647$1.03B0.35%−463,346−11.5%Reduced
Loomis Sayles & Co L P3,759,170$1.09B2.17%−399,220−9.6%Reduced
Massachusetts Financial Services Co4,111,555$1.19B0.41%−235,176−5.4%Reduced
Price T Rowe Associates Inc4,697,667$1.36B0.22%−460,287−8.9%Reduced
Jennison Associates LLC5,115,540$1.48B1.52%+359,719+7.6%Added
Geode Capital Management, LLC5,382,719$1.55B0.22%+111,052+2.1%Added
JPMorgan Chase & Co5,490,408$1.59B0.22%+630,721+13.0%Added
Wellington Management Group LLP6,827,583$1.97B0.40%−1,201,759−15.0%Reduced
Alliancebernstein L.P.9,069,580$2.62B1.18%−75,936−0.8%Reduced
State Street Corp12,370,430$3.57B0.21%+75,639+0.6%Added
Capital World Investors12,769,006$3.69B0.79%+244,327+2.0%Added
FMR LLC17,866,291$5.16B0.51%+500,268+2.9%Added
Vanguard Group Inc21,546,903$6.22B0.17%+414,567+2.0%Added
BlackRock Inc.24,241,437$7.00B0.22%−1,001,623−4.0%Reduced
Palouse Capital Management, Inc.4,185––−281−6.3%Reduced
Employees Retirement System of Texas0$00.00%−81,000−100.0%Sold out
ING Groep NV0$00.00%−60,025−100.0%Sold out
Distillate Capital Partners LLC0$00.00%−25,252−100.0%Sold out
Point72 Hong Kong Ltd0$00.00%−16,683−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−14,195−100.0%Sold out
David J Yvars Group0$00.00%−13,495−100.0%Sold out
Liontrust Investment Partners LLP0$00.00%−10,640−100.0%Sold out
OPSEU Pension Plan Trust Fund0$00.00%−8,500−100.0%Sold out
Aigen Investment Management, LP0$00.00%−6,692−100.0%Sold out
E Fund Management (Hong Kong) Co., Ltd.0$00.00%−6,500−100.0%Sold out
AlphaCrest Capital Management LLC0$00.00%−5,910−100.0%Sold out
SWS Partners0$00.00%−5,592−100.0%Sold out
Edgestream Partners, L.P.0$00.00%−5,068−100.0%Sold out
Lynwood Capital Management Inc.0$00.00%−5,000−100.0%Sold out
Berkshire Asset Management LLC0$00.00%−4,969−100.0%Sold out
Jackson Wealth Management, LLC0$00.00%−4,880−100.0%Sold out
Virtus Family Office LLC0$00.00%−3,316−100.0%Sold out
Phoenix Holdings Ltd.0$00.00%−2,726−100.0%Sold out
DCM Advisors, LLC0$00.00%−2,566−100.0%Sold out
O'Neil Global Advisors, Inc.0$00.00%−2,100−100.0%Sold out
Jump Financial, LLC0$00.00%−1,917−100.0%Sold out
Wintrust Investments LLC0$00.00%−1,909−100.0%Sold out
Cresset Asset Management, LLC0$00.00%−1,812−100.0%Sold out
Wolverine Trading, LLC0$00.00%−1,598−100.0%Sold out
Financial Advocates Investment Management0$00.00%−12,405−100.0%Sold out
Independent Advisor Alliance0$00.00%−1,195−100.0%Sold out
Silver Oak Securities, Inc0$00.00%−994−100.0%Sold out
Stoneridge Investment Partners LLC0$00.00%−1,144−100.0%Sold out
Highland Private Wealth Management0$00.00%−1,066−100.0%Sold out
Clear Street Markets LLC0$00.00%−1,008−100.0%Sold out
Q3 Asset Management0$00.00%−943−100.0%Sold out
ARGI Investment Services, LLC0$00.00%−915−100.0%Sold out
Blueprint Investment Partners LLC0$00.00%−910−100.0%Sold out
First Long Island Investors, LLC0$00.00%−903−100.0%Sold out
Centric Wealth Management0$00.00%−885−100.0%Sold out
Martin Capital Partners, LLC0$00.00%−800−100.0%Sold out
Arthur M. Cohen & Associates, LLC0$00.00%−775−100.0%Sold out
Claraphi Advisory Network, LLC0$00.00%−771−100.0%Sold out
Gitterman Wealth Management, LLC0$00.00%−768−100.0%Sold out
RiverTree Advisors, LLC0$00.00%−753−100.0%Sold out
Seven Post Investment Office LP0$00.00%−750−100.0%Sold out
M&G Investment Management Ltd0$00.00%−742−100.0%Sold out
Clare Market Investments LLC0$00.00%−735−100.0%Sold out
Integrated Wealth Concepts LLC0$00.00%−733−100.0%Sold out
Western Wealth Management, LLC0$00.00%−722−100.0%Sold out
Laurion Capital Management LP0$00.00%−705−100.0%Sold out
First Capital Advisors Group, LLC.0$00.00%−705−100.0%Sold out
LifePro Asset Management0$00.00%−697−100.0%Sold out
Cutler Group LP0$00.00%−200−100.0%Sold out
GPS Wealth Strategies Group, LLC0$00.00%−172−100.0%Sold out
Evoke Wealth, LLC0$00.00%−166−100.0%Sold out
Hudock, Inc.0$00.00%−164−100.0%Sold out
Optimum Investment Advisors0$00.00%−150−100.0%Sold out
Stephens Consulting, LLC0$00.00%−132−100.0%Sold out
Axiom Investment Management LLC0$00.00%−108−100.0%Sold out
Wagner Wealth Management, LLC0$00.00%−100−100.0%Sold out
Selective Wealth Management, Inc.0$00.00%−100−100.0%Sold out
MUFG Americas Holdings Corp0$00.00%−50−100.0%Sold out
IAG Wealth Partners, LLC0$00.00%−50−100.0%Sold out
Cary Street Partners Asset Management LLC0$00.00%−37−100.0%Sold out
Optiver Holding B.V.0$00.00%−32−100.0%Sold out
EdgeRock Capital LLC0$00.00%−16−100.0%Sold out
HM Payson & Co0$00.00%−12−100.0%Sold out
Osterweis Capital Management Inc0$00.00%−6−100.0%Sold out
Eaton Vance Management––––Not filed
Roosevelt Investment Group LLC––––Not filed
Andrew Hill Investment Advisors, Inc.––––Not filed
Regentatlantic Capital LLC––––Not filed
USA Financial Portformulas Corp––––Not filed
Colrain Capital LLC––––Not filed
American Research & Management Co.––––Not filed
AGF Investments LLC––––Not filed
Bowling Portfolio Management LLC––––Not filed
Redpoint Investment Management Pty Ltd––––Not filed
Corient Capital Partners, LLC––––Not filed
Balasa Dinverno & Foltz LLC––––Not filed