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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2022

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,224
+121 vs. Q3 2022
Shares held
237.1M
+549.4K (+0.2%) vs. Q3 2022
Total value
$68.3B
−$59.7M (−0.1%) vs. Q3 2022
New holders
185
438 more added
Sold out
64
440 more reduced

24 institutions that held it in Q3 2022 haven't filed for Q4 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2022: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2022: 1,224 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ4 2022: $68.3B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2022

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2022.

Institutions holding VRTX in Q4 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Banque Pictet & Cie SA24,268$7.01M0.07%−22,285−47.9%Reduced
Aquatic Capital Management LLC24,600$7.10M0.52%+24,600New
Bridgeway Capital Management, LLC25,650$7.41M0.19%00.0%Unchanged
Gotham Asset Management, LLC25,740$7.43M0.21%−11,867−31.6%Reduced
Meritage Portfolio Management25,849$7.46M0.58%−1,215−4.5%Reduced
Fisher Asset Management, LLC26,069$7.53M0.01%+486+1.9%Added
Beacon Pointe Advisors, LLC26,336$7.61M0.15%−546−2.0%Reduced
Fifth Third Bancorp26,474$7.65M0.04%+1,387+5.5%Added
Credit Agricole S A26,775$7.73M0.29%+13,618+103.5%Added
Atria Investments LLC27,644$7.98M0.16%−105−0.4%Reduced
Weiss Multi-Strategy Advisers LLC27,902$8.06M0.23%−5,969−17.6%Reduced
Ilmarinen Mutual Pension Insurance Co28,000$8.09M0.12%00.0%Unchanged
Investment Management Corp of Ontario28,097$8.11M0.40%+28,097New
Greenwood Capital Associates LLC28,143$8.13M1.33%−2,276−7.5%Reduced
Lido Advisors, LLC28,232$8.15M0.14%+12,234+76.5%Added
Intech Investment Management LLC28,487$8.23M0.06%+5,843+25.8%Added
Bender Robert & Associates28,859$8.33M3.12%+50.0%Added
Two Sigma Investments, LP29,122$8.41M0.03%+29,122New
Bulltick Wealth Management, LLC29,236$8.44M2.42%−5,555−16.0%Reduced
Raymond James Financial Services Advisors, Inc.29,276$8.45M0.02%+6,273+27.3%Added
Louisiana State Employees Retirement System29,400$8.49M0.23%−800−2.6%Reduced
Daiwa Securities Group Inc.29,662$8.57M0.07%+388+1.3%Added
Czech National Bank30,046$8.68M0.23%+242+0.8%Added
J. Goldman & Co LP30,168$8.71M0.61%+30,168New
Engineers Gate Manager LP30,297$8.75M0.53%+27,959+1,195.9%Added
ExodusPoint Capital Management, LP30,468$8.80M0.14%+30,468New
Nissay Asset Management Corp31,610$9.13M0.09%−1,204−3.7%Reduced
Mariner, LLC31,765$9.20M0.03%+13,022+69.5%Added
Lindbrook Capital, LLC31,939$9.22M1.14%+24,198+312.6%Added
Public Sector Pension Investment Board31,958$9.23M0.07%+4,468+16.3%Added
Hudson Bay Capital Management LP32,000$9.24M0.11%+32,000New
LVM Capital Management Ltd33,120$9.56M1.39%−1,240−3.6%Reduced
Cantor Fitzgerald, L. P.33,119$9.56M0.21%+33,119New
CIBC World Markets Corp33,230$9.60M0.06%+29,339+754.0%Added
Point72 Middle East FZE33,235$9.60M0.74%+33,235New
2Xideas AG33,960$9.81M1.04%+1,776+5.5%Added
Washington Trust Bank34,219$9.88M1.12%+34,219New
Wealthfront Advisers LLC34,996$10.1M0.05%−3,525−9.2%Reduced
Privium Fund Management B.V.35,307$10.2M3.87%+6,807+23.9%Added
Verition Fund Management LLC35,686$10.3M0.20%−21,728−37.8%Reduced
McRae Capital Management Inc35,759$10.3M3.02%−606−1.7%Reduced
Yousif Capital Management, LLC35,863$10.4M0.14%+3,777+11.8%Added
Seizert Capital Partners, LLC36,381$10.5M0.56%−3,438−8.6%Reduced
Texas Permanent School Fund36,471$10.5M0.16%+184+0.5%Added
Mutual of America Capital Management LLC36,631$10.6M0.13%+1,158+3.3%Added
Banco Santander, S.A.37,335$10.8M0.16%−4,135−10.0%Reduced
Capital International Inc37,431$10.8M0.23%−5,379−12.6%Reduced
Balyasny Asset Management LLC37,821$10.9M0.04%+37,821New
Marvin & Palmer Associates Inc39,155$11.3M5.96%00.0%Unchanged
First Republic Investment Management, Inc.40,318$11.6M0.03%−3,842−8.7%Reduced
Longbow Finance SA41,063$11.9M1.60%+41,063New
Profund Advisors LLC41,266$11.9M0.77%−180.0%Reduced
Comerica Bank38,736$12.1M0.09%+3,190+9.0%Added
EULAV Asset Management42,000$12.1M0.52%−6,010−12.5%Reduced
PFS Investments Inc.42,504$12.3M0.23%−1,560−3.5%Reduced
Gulf International Bank (UK) Ltd42,577$12.3M0.22%00.0%Unchanged
Bank of Nova Scotia42,668$12.3M0.03%+8,942+26.5%Added
Factory Mutual Insurance Co43,200$12.5M0.19%00.0%Unchanged
Shelter Mutual Insurance Co43,300$12.5M3.59%00.0%Unchanged
Commonwealth of Pennsylvania Public School Empls Retrmt Sys43,390$12.5M0.11%+5,878+15.7%Added
Umb Bank N A43,408$12.5M0.20%+1,042+2.5%Added
Squarepoint Ops LLC43,497$12.6M0.09%+43,497New
Swiss Life Asset Management Ltd43,667$12.6M0.21%+4,866+12.5%Added
Azimuth Capital Investment Management LLC43,783$12.6M0.64%+8,353+23.6%Added
Citizens Financial Group Inc43,930$12.7M0.50%−1,770−3.9%Reduced
Andra AP-fonden44,000$12.7M0.39%−13,000−22.8%Reduced
Jag Capital Management, LLC44,051$12.7M1.85%−2,037−4.4%Reduced
Group One Trading, L.P.45,103$13.0M0.44%+20,221+81.3%Added
Utah Retirement Systems45,379$13.1M0.21%−469−1.0%Reduced
IFM Investors Pty Ltd45,715$13.2M0.22%+1,184+2.7%Added
Clough Capital Partners L P47,211$13.6M1.38%+32,530+221.6%Added
Rockefeller Capital Management L.P.47,544$13.7M0.07%−241−0.5%Reduced
South Dakota Investment Council47,601$13.7M0.31%−11,813−19.9%Reduced
Achmea Investment Management B.V.51,394$13.9M0.47%+1,154+2.3%Added
Nicholas Investment Partners, LP48,241$13.9M1.22%−14,538−23.2%Reduced
USS Investment Management Ltd48,314$13.9M0.20%00.0%Unchanged
Westpac Banking Corp50,028$14.4M0.21%+13,809+38.1%Added
BI Asset Management Fondsmaeglerselskab A/S50,047$14.5M0.38%+3,705+8.0%Added
Industrial Alliance Investment Management Inc.50,189$14.5M0.40%−12,559−20.0%Reduced
Capital International Sarl50,770$14.7M1.03%+3,057+6.4%Added
Trexquant Investment LP52,220$15.1M0.43%+23,040+79.0%Added
New York Life Investment Management LLC52,506$15.2M0.17%−242−0.5%Reduced
Dai-Ichi Life Insurance Company, Ltd52,594$15.2M0.35%00.0%Unchanged
W.G. Shaheen & Associates DBA Whitney & Co52,862$15.3M2.80%+643+1.2%Added
Vident Investment Advisory, LLC53,252$15.4M0.58%+21,209+66.2%Added
Davidson Investment Advisors54,903$15.9M1.23%+418+0.8%Added
Churchill Management Corp55,174$15.9M0.39%+47,196+591.6%Added
Edgemoor Investment Advisors, Inc.55,520$16.0M2.01%−310−0.6%Reduced
De Burlo Group Inc55,740$16.1M3.60%−6,680−10.7%Reduced
Walleye Capital LLC55,837$16.1M0.35%−11,186−16.7%Reduced
Xponance, Inc.56,140$16.2M0.26%+4,870+9.5%Added
Freemont Management S.A.57,700$16.7M2.66%+17,200+42.5%Added
Advisor Group Holdings, Inc.57,772$16.7M0.03%−4,952−7.9%Reduced
Scout Investments, Inc.57,995$16.7M0.34%−56,701−49.4%Reduced
Foster Dykema Cabot & Co Inc58,352$16.9M2.36%+14,461+32.9%Added
Varma Mutual Pension Insurance Co60,000$17.3M0.24%+15,492+34.8%Added
Baird Financial Group, Inc.60,207$17.4M0.05%+4,055+7.2%Added
Nationale-Nederlanden Powszechne Towarzystwo Emerytalne S.A.60,527$17.5M7.60%+1,436+2.4%Added
Voloridge Investment Management, LLC60,891$17.6M0.10%+60,891New
Forsta Ap-Fonden61,400$17.7M0.20%+6,600+12.0%Added