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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

No open-market purchases or sales by Vertex Pharmaceuticals Inc insiders were filed in the last 90 days; 1,762 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q1 2022

Institutional positions in Vertex Pharmaceuticals Inc as of Mar 31, 2022. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,072
+48 vs. Q4 2021
Shares held
235.3M
+5.08M (+2.2%) vs. Q4 2021
Total value
$60.9B
+$10.5B (+20.9%) vs. Q4 2021
New holders
150
417 more added
Sold out
102
373 more reduced

10 institutions that held it in Q4 2021 haven't filed for Q1 2022 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2022: 1,072 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,072 institutionsQ2 2022: 1,109 institutionsQ3 2022: 1,127 institutionsQ4 2022: 1,224 institutionsQ1 2023: 1,212 institutionsQ2 2023: 1,287 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,617 institutionsQ2 2025: 1,563 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,762 institutions
Value heldQ1 2022: $60.9B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,762$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,563$107.2B
Q1 20251,617$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,287$83.3B
Q1 20231,212$75.0B
Q4 20221,224$68.3B
Q3 20221,127$68.5B
Q2 20221,109$66.1B
Q1 20221,072$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q1 2022

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q4 2021.

Institutions holding VRTX in Q1 2022
InstitutionSharesValue% of portfolioChange in sharesAction
Mutual of America Capital Management LLC33,946$8.86M0.09%+396+1.2%Added
Commonwealth of Pennsylvania Public School Empls Retrmt Sys34,063$8.89M0.09%+2,150+6.7%Added
Bulltick Wealth Management, LLC34,798$9.08M2.07%−5,374−13.4%Reduced
Azimuth Capital Management LLC34,984$9.13M0.39%+1,409+4.2%Added
Public Sector Pension Investment Board35,725$9.32M0.06%−6,700−15.8%Reduced
State of Alaska, Department of Revenue35,815$9.35M0.10%−985−2.7%Reduced
Achmea Investment Management B.V.36,132$9.43M0.25%+36,132New
Mackay Shields LLC36,585$9.55M0.08%−1,398−3.7%Reduced
Rockefeller Capital Management L.P.36,928$9.64M0.05%+6,807+22.6%Added
Comerica Bank34,619$9.88M0.07%+294+0.9%Added
Gabelli Funds LLC37,962$9.91M0.07%+6,666+21.3%Added
Spire Wealth Management38,059$9.94M0.27%+35,416+1,340.0%Added
Exencial Wealth Advisors, LLC38,900$10.2M0.51%+1,083+2.9%Added
British Columbia Investment Management Corp39,252$10.2M0.07%−6,360−13.9%Reduced
Varma Mutual Pension Insurance Co39,287$10.3M0.12%+10,000+34.1%Added
Prudential PLC39,288$10.3M0.15%+3,247+9.0%Added
National Bank of Canada36,076$10.3M0.04%+29,337+435.3%Added
Seizert Capital Partners, LLC40,078$10.5M0.48%+1,480+3.8%Added
Vident Investment Advisory, LLC41,454$10.8M0.28%+11,330+37.6%Added
Weiss Multi-Strategy Advisers LLC41,500$10.8M0.26%−3,193−7.1%Reduced
Westpac Banking Corp41,571$10.8M0.12%+15,571+59.9%Added
IFM Investors Pty Ltd41,731$10.9M0.17%+7,534+22.0%Added
Capital International Sarl42,027$11.0M0.54%−4,528−9.7%Reduced
Employees Retirement System of Texas42,200$11.0M0.13%00.0%Unchanged
Marvin & Palmer Associates Inc42,546$11.1M5.00%+42,546New
Citadel Advisors LLC42,605$11.1M0.01%−209,986−83.1%Reduced
Industrial Alliance Investment Management Inc.43,002$11.2M0.27%−4,630−9.7%Reduced
Factory Mutual Insurance Co43,200$11.3M0.15%00.0%Unchanged
Shelter Mutual Insurance Co43,300$11.3M2.96%00.0%Unchanged
Gulf International Bank (UK) Ltd43,475$11.3M0.17%00.0%Unchanged
Bank of Nova Scotia43,478$11.3M0.02%−57,781−57.1%Reduced
Illinois Municipal Retirement Fund44,800$11.7M0.34%−13,702−23.4%Reduced
SEI Investments Co44,090$11.8M0.02%+9,761+28.4%Added
Utah Retirement Systems45,439$11.9M0.16%−800−1.7%Reduced
Citizens Financial Group Inc47,889$12.5M0.44%+389+0.8%Added
Caption Management, LLC48,358$12.6M0.84%+41,958+655.6%Added
Profund Advisors LLC49,098$12.8M0.54%−9,510−16.2%Reduced
W.G. Shaheen & Associates DBA Whitney & Co51,524$13.4M2.07%+1,389+2.8%Added
Martingale Asset Management L P52,696$13.8M0.21%+41,677+378.2%Added
Jacobs Levy Equity Management, Inc53,033$13.8M0.09%+17,769+50.4%Added
Advisor Group Holdings, Inc.54,900$14.1M0.03%+6,371+13.1%Added
Edgemoor Investment Advisors, Inc.55,153$14.4M1.52%+10,825+24.4%Added
Banco Santander, S.A.55,192$14.4M0.15%+7,930+16.8%Added
PFS Investments Inc.56,891$14.8M0.28%−11,892−17.3%Reduced
Capital Group Private Client Services, Inc.57,226$14.9M0.16%+60+0.1%Added
Forsta Ap-Fonden57,500$15.0M0.17%−19,800−25.6%Reduced
Clough Capital Partners L P58,150$15.2M1.16%−48,960−45.7%Reduced
Rafferty Asset Management, LLC58,417$15.2M0.09%+3,982+7.3%Added
CIBC World Markets Corp59,740$15.6M0.12%+59,740New
EULAV Asset Management60,007$15.7M0.47%−19,993−25.0%Reduced
Capital International Inc60,056$15.7M0.18%−47,117−44.0%Reduced
Schroder Investment Management Group61,253$15.7M0.02%+15,359+33.5%Added
Baird Financial Group, Inc.61,809$16.1M0.04%−14,219−18.7%Reduced
Nicholas Investment Partners, LP62,069$16.2M1.15%+23,782+62.1%Added
Capital International Ltd63,256$16.5M0.94%−20,335−24.3%Reduced
State of Michigan Retirement System64,223$16.8M0.10%+189+0.3%Added
Colony Group LLC64,585$16.9M0.25%+64,585New
Davidson Investment Advisors65,227$17.0M1.23%+918+1.4%Added
CIBC Asset Management Inc67,587$17.6M0.06%−55−0.1%Reduced
De Burlo Group Inc68,410$17.9M3.32%+68,410New
BI Asset Management Fondsmaeglerselskab A/S69,046$18.0M0.69%−9,831−12.5%Reduced
Amalgamated Bank69,389$18.1M0.14%−1,785−2.5%Reduced
Amalgamated Financial Corp.69,389$18.1M0.14%+69,389New
Arizona State Retirement System69,766$18.2M0.15%−1,286−1.8%Reduced
Fjarde Ap-Fonden /Fourth Swedish National Pension Fund70,086$18.3M0.18%−401−0.6%Reduced
USS Investment Management Ltd70,320$18.4M0.15%+5,908+9.2%Added
Commonwealth Equity Services, LLC70,840$18.5M0.04%+5,437+8.3%Added
The PNC Financial Services Group, Inc.71,164$18.6M0.02%+19,627+38.1%Added
Vestcor Inc71,708$18.7M0.64%+65,551+1,064.7%Added
2Xideas AG71,765$18.7M1.32%−8,461−10.5%Reduced
Beacon Investment Advisory Services, Inc.73,093$19.1M0.81%+42,536+139.2%Added
MetLife Investment Management73,825$19.3M0.12%+17,650+31.4%Added
Woodline Partners LP74,671$19.5M0.32%−29,109−28.0%Reduced
Nisa Investment Advisors, LLC75,067$19.6M0.14%−10,995−12.8%Reduced
SG Americas Securities, LLC75,285$19.6M0.18%+41,131+120.4%Added
Banco Bilbao Vizcaya Argentaria, S.A.72,852$19.7M0.27%−1,787−2.4%Reduced
Van Hulzen Asset Management, LLC77,300$20.2M2.14%+7,399+10.6%Added
Tower Research Capital LLC (TRC)77,497$20.2M0.19%+47,754+160.6%Added
Stifel Financial Corp81,543$21.3M0.03%−14,790−15.4%Reduced
Nikko Asset Management Americas, Inc.81,535$21.4M0.16%−32,454−28.5%Reduced
Grantham, Mayo, Van Otterloo & Co. LLC82,100$21.4M0.10%+82,100New
Eagle Health Investments LP82,144$21.4M5.28%00.0%Unchanged
Erste Asset Management GmbH84,000$21.6M0.41%+22,800+37.3%Added
Bridger Management, LLC82,800$21.6M3.54%+23,400+39.4%Added
Pura Vida Investments, LLC84,057$21.9M2.65%+59,421+241.2%Added
Great Point Partners LLC85,000$22.2M5.37%00.0%Unchanged
Banque Pictet & Cie SA85,596$22.3M0.17%−6,905−7.5%Reduced
Cubist Systematic Strategies, LLC86,574$22.6M0.19%+54,686+171.5%Added
Chiron Investment Management, LLC87,121$22.7M2.67%+87,121New
Gateway Investment Advisers LLC87,253$22.8M0.22%−2,693−3.0%Reduced
Vontobel Holding Ltd.90,691$23.3M0.20%−26,006−22.3%Reduced
Rhenman & Partners Asset Management AB89,500$23.4M2.30%−75,500−45.8%Reduced
Royal London Asset Management Ltd89,765$23.4M0.09%+2,978+3.4%Added
Hallmark Capital Management Inc90,503$23.6M1.97%−4,735−5.0%Reduced
Summit Global Investments90,562$23.6M1.74%−4,482−4.7%Reduced
Alberta Investment Management Corp91,200$23.8M0.14%+12,000+15.2%Added
South Dakota Investment Council93,495$24.4M0.48%−30,799−24.8%Reduced
Ossiam94,074$24.6M0.64%+4,020+4.5%Added
HighTower Advisors, LLC94,309$24.6M0.05%+29,446+45.4%Added
Sofinnova Investments, Inc.95,003$24.8M2.08%+95,003New