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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,034
+113 vs. Q3 2021
Shares held
230.3M
−775.4K (−0.3%) vs. Q3 2021
Total value
$50.4B
+$8.64B (+20.7%) vs. Q3 2021
New holders
201
334 more added
Sold out
88
369 more reduced

15 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 1,034 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ4 2021: $50.4B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2021.

Institutions holding VRTX in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Y-Intercept (Hong Kong) Ltd7,996$1.76M0.42%+7,996New
Highland Capital Management, LLC8,080$1.77M0.10%−20.0%Reduced
Koss-Olinger Consulting, LLC8,120$1.78M0.27%+4,355+115.7%Added
Wrapmanager Inc8,122$1.78M0.45%−996−10.9%Reduced
Siemens Fonds Invest GmbH8,206$1.82M0.12%+381+4.9%Added
Grandfield & Dodd, LLC8,440$1.85M0.12%+519+6.6%Added
Bangor Savings Bank8,445$1.85M0.18%+446+5.6%Added
Johnson Investment Counsel Inc8,455$1.86M0.02%−508−5.7%Reduced
Bensler, LLC8,665$1.90M0.53%+8,665New
Northeast Financial Consultants Inc8,672$1.90M0.12%−465−5.1%Reduced
SFMG, LLC8,980$1.97M0.19%+1,070+13.5%Added
Acadian Asset Management LLC9,077$1.99M0.01%−328,874−97.3%Reduced
Schonfeld Strategic Advisors LLC9,132$2.00M0.02%−21,465−70.2%Reduced
M&T Bank Corp9,143$2.01M0.01%+65+0.7%Added
Level Four Advisory Services, LLC9,227$2.03M0.15%−576−5.9%Reduced
Horizon Investments, LLC9,466$2.08M0.06%+6,725+245.3%Added
Mercer Global Advisors Inc9,473$2.08M0.01%+2,251+31.2%Added
American Research & Management Co.9,510$2.09M0.45%+75+0.8%Added
Point72 Hong Kong Ltd9,586$2.10M0.18%−15,655−62.0%Reduced
Ashford Capital Management Inc9,757$2.14M0.21%+1,568+19.1%Added
SWS Partners9,857$2.17M1.23%+2,508+34.1%Added
Engineers Gate Manager LP9,942$2.18M0.10%−33,802−77.3%Reduced
Berkshire Asset Management LLC9,982$2.19M0.13%−205−2.0%Reduced
Colrain Capital LLC10,000$2.20M3.54%+1,700+20.5%Added
F/M Investments LLC10,085$2.21M1.62%+10,085New
Myriad Asset Management Ltd.10,400$2.28M0.25%00.0%Unchanged
JustInvest LLC10,495$2.31M0.14%+5,739+120.7%Added
Arden Trust Co10,535$2.31M0.39%−4,491−29.9%Reduced
TD Private Client Wealth LLC10,706$2.35M0.10%−649−5.7%Reduced
Martingale Asset Management L P11,019$2.42M0.03%+5,687+106.7%Added
Phoenix Holdings Ltd.11,042$2.47M0.04%−1,260−10.2%Reduced
Slow Capital, Inc.11,277$2.48M0.42%−4,111−26.7%Reduced
Howe & Rusling Inc11,289$2.48M0.29%−946−7.7%Reduced
Central Trust Co11,460$2.52M0.07%−3,000−20.7%Reduced
Pensionfund Sabic11,500$2.52M0.47%+11,500New
Stephens Inc11,503$2.53M0.04%−2,496−17.8%Reduced
Bokf, NA11,588$2.54M0.04%−1,445−11.1%Reduced
Heirloom Wealth Management11,200$2.57M2.21%+11,200New
PEAK6 Investments LLC11,815$2.60M0.07%−23,374−66.4%Reduced
National Asset Management, Inc.11,814$2.60M0.07%−5,007−29.8%Reduced
Capstone Investment Advisors, LLC12,060$2.65M0.04%−89,256−88.1%Reduced
Exchange Traded Concepts, LLC12,110$2.66M0.05%−3,346−21.6%Reduced
Cambridge Investment Research Advisors, Inc.12,189$2.68M0.01%−45−0.4%Reduced
Two Sigma Advisers, LP12,300$2.70M0.01%−770,400−98.4%Reduced
Bridgewater Associates, LP12,417$2.73M0.02%−2,700−17.9%Reduced
Cutter & CO Brokerage, Inc.12,430$2.73M0.75%+310+2.6%Added
Berry Street Capital Management LLP12,500$2.75M0.53%+12,500New
Northwestern Mutual Investment Management Company, LLC12,616$2.77M0.05%−382−2.9%Reduced
E. Ohman J:or Asset Management AB12,800$2.81M0.08%+900+7.6%Added
MML Investors Services, LLC12,862$2.82M0.02%+1,729+15.5%Added
First Citizens Bank & Trust Co12,967$2.85M0.11%+164+1.3%Added
Seeyond13,123$2.88M0.27%+3,655+38.6%Added
Boothbay Fund Management, LLC13,421$2.95M0.10%+635+5.0%Added
Brinker Capital Investments, LLC13,424$2.95M0.04%+2,301+20.7%Added
Cookson Peirce & Co Inc13,537$2.97M0.17%+13,537New
Simplex Trading, LLC13,565$2.98M0.10%+4,265+45.9%Added
Cetera Investment Advisers13,570$2.98M0.04%−312−2.2%Reduced
Leonteq Securities AG13,720$3.01M0.14%−27,760−66.9%Reduced
Te Ahumairangi Investment Management Ltd13,770$3.02M0.39%+13,770New
Glenmede Trust Co NA13,947$3.06M0.01%−1,345−8.8%Reduced
Kinneret Advisory, LLC14,025$3.08M0.32%00.0%Unchanged
Silvercrest Asset Management Group LLC14,070$3.09M0.02%00.0%Unchanged
Barrett Asset Management, LLC14,183$3.12M0.12%−14,427−50.4%Reduced
US Bancorp14,189$3.12M0.00%+1,895+15.4%Added
Tealwood Asset Management Inc14,297$3.14M1.26%−595−4.0%Reduced
FDx Advisors, Inc.14,566$3.20M0.09%+4,443+43.9%Added
Oppenheimer Asset Management Inc.14,711$3.23M0.04%+3,268+28.6%Added
Madison Asset Management, LLC14,728$3.23M0.04%−403−2.7%Reduced
Ausdal Financial Partners, Inc.14,981$3.29M0.44%+14,981New
Nomura Holdings Inc15,101$3.32M0.02%−320−2.1%Reduced
Swiss Life Asset Management Ltd15,111$3.32M0.04%−35,848−70.3%Reduced
Enterprise Trust & Investment Co15,340$3.37M1.18%+7,415+93.6%Added
Kentucky Retirement Systems15,368$3.38M0.14%+111+0.7%Added
Livforsakringsbolaget Skandia, Omsesidigt15,387$3.38M0.21%−1,500−8.9%Reduced
Harvest Volatility Management LLC15,516$3.41M0.17%+3,573+29.9%Added
Essex Investment Management Co LLC15,570$3.42M0.39%−1,060−6.4%Reduced
Princeton Global Asset Management LLC15,782$3.47M0.97%−1,058−6.3%Reduced
Winton Group Ltd15,797$3.47M0.21%+12,962+457.2%Added
New Mexico Educational Retirement Board15,800$3.47M0.12%−1,100−6.5%Reduced
Fifth Third Bancorp15,923$3.50M0.01%−1,130−6.6%Reduced
Boston Private Wealth LLC16,372$3.60M0.06%+98+0.6%Added
Princeton Capital Management LLC16,581$3.64M1.04%−510−3.0%Reduced
Captrust Financial Advisors16,686$3.66M0.03%−2,612−13.5%Reduced
Knott David M Jr17,000$3.73M1.41%+17,000New
Telos Capital Management, Inc.17,099$3.75M0.47%+581+3.5%Added
U.S. Capital Wealth Advisors, LLC17,110$3.76M0.15%−494−2.8%Reduced
Ameritas Investment Partners, Inc.17,457$3.83M0.13%−252−1.4%Reduced
PointState Capital LP17,500$3.84M0.12%+17,500New
Knuff & Co LLC17,646$3.88M1.20%+634+3.7%Added
IndexIQ Advisors LLC17,937$3.94M0.13%+195+1.1%Added
Jump Financial, LLC18,167$3.99M0.25%+18,167New
Pictet & Cie (Europe) SA18,242$4.01M0.14%−555−3.0%Reduced
Kestra Advisory Services, LLC18,677$4.10M0.04%−1,802−8.8%Reduced
Wolverine Trading, LLC18,569$4.13M0.06%−4,402−19.2%Reduced
Allstate Corp19,082$4.19M0.08%+12,315+182.0%Added
Maryland State Retirement & Pension System19,543$4.29M0.11%00.0%Unchanged
Elo Mutual Pension Insurance Co19,658$4.32M0.12%+1,392+7.6%Added
Keybank National Association19,769$4.34M0.02%−7,086−26.4%Reduced
Camden National Bank19,807$4.35M0.76%+281+1.4%Added
Vestmark Advisory Solutions, Inc.19,982$4.39M0.25%−357−1.8%Reduced