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Vertex Pharmaceuticals Inc

VRTX
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0000875320

In the last 90 days, Vertex Pharmaceuticals Inc insiders filed 0 open-market purchases and 3 sales; 1,763 institutions reported holding it in 13F filings for Q2 2026, worth $119.7B in total; no superinvestor holds it.

13F holders, Q4 2021

Institutional positions in Vertex Pharmaceuticals Inc as of Dec 31, 2021. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
1,034
+113 vs. Q3 2021
Shares held
230.3M
−775.4K (−0.3%) vs. Q3 2021
Total value
$50.4B
+$8.64B (+20.7%) vs. Q3 2021
New holders
201
334 more added
Sold out
88
369 more reduced

15 institutions that held it in Q3 2021 haven't filed for Q4 2021 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q3 2021: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting VRTX on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2021: 1,034 institutions
Q1 2021: 1,000 institutionsQ2 2021: 979 institutionsQ3 2021: 936 institutionsQ4 2021: 1,034 institutionsQ1 2022: 1,073 institutionsQ2 2022: 1,110 institutionsQ3 2022: 1,128 institutionsQ4 2022: 1,225 institutionsQ1 2023: 1,213 institutionsQ2 2023: 1,288 institutionsQ3 2023: 1,280 institutionsQ4 2023: 1,442 institutionsQ1 2024: 1,497 institutionsQ2 2024: 1,551 institutionsQ3 2024: 1,551 institutionsQ4 2024: 1,563 institutionsQ1 2025: 1,618 institutionsQ2 2025: 1,564 institutionsQ3 2025: 1,523 institutionsQ4 2025: 1,671 institutionsQ1 2026: 1,698 institutionsQ2 2026: 1,763 institutions
Value heldQ4 2021: $50.4B
Q1 2021: $50.6BQ2 2021: $46.8BQ3 2021: $41.9BQ4 2021: $50.4BQ1 2022: $60.9BQ2 2022: $66.1BQ3 2022: $68.5BQ4 2022: $68.3BQ1 2023: $75.0BQ2 2023: $83.3BQ3 2023: $81.9BQ4 2023: $95.7BQ1 2024: $98.0BQ2 2024: $109.9BQ3 2024: $109.1BQ4 2024: $95.2BQ1 2025: $116.3BQ2 2025: $107.2BQ3 2025: $90.8BQ4 2025: $109.5BQ1 2026: $106.1BQ2 2026: $119.7B
Institutions holding VRTX and their total value by quarter
QuarterHoldersValue
Q2 20261,763$119.7B
Q1 20261,698$106.1B
Q4 20251,671$109.5B
Q3 20251,523$90.8B
Q2 20251,564$107.2B
Q1 20251,618$116.3B
Q4 20241,563$95.2B
Q3 20241,551$109.1B
Q2 20241,551$109.9B
Q1 20241,497$98.0B
Q4 20231,442$95.7B
Q3 20231,280$81.9B
Q2 20231,288$83.3B
Q1 20231,213$75.0B
Q4 20221,225$68.3B
Q3 20221,128$68.5B
Q2 20221,110$66.1B
Q1 20221,073$60.9B
Q4 20211,034$50.4B
Q3 2021936$41.9B
Q2 2021979$46.8B
Q1 20211,000$50.6B

Institutions, Q4 2021

Shares, value and share of portfolio for each institution holding Vertex Pharmaceuticals Inc; share changes are against Q3 2021.

Institutions holding VRTX in Q4 2021
InstitutionSharesValue% of portfolioChange in sharesAction
Goldman Sachs Group Inc1,187,377$260.7M0.06%−206,385−14.8%Reduced
Pictet Asset Management SA1,212,319$266.2M0.27%+147,497+13.9%Added
Caisse de Depot Et Placement du Quebec1,228,508$269.8M0.58%−266,708−17.8%Reduced
Charles Schwab Investment Management Inc1,261,688$277.1M0.08%+19,703+1.6%Added
Nuveen Asset Management, LLC1,343,834$295.1M0.09%−21,391−1.6%Reduced
Renaissance Technologies LLC1,626,868$357.3M0.44%−264,618−14.0%Reduced
Canada Pension Plan Investment Board1,708,354$375.2M0.40%+15,560+0.9%Added
Bellevue Group AG1,791,761$393.5M4.06%+30,145+1.7%Added
Harding Loevner LP1,881,871$413.3M1.58%−29,232−1.5%Reduced
Legal & General Group Plc1,898,644$416.9M0.13%−169,690−8.2%Reduced
California Public Employees Retirement System1,938,819$425.8M0.28%−67,499−3.4%Reduced
Janus Henderson Group PLC1,990,740$437.2M0.18%−144,038−6.7%Reduced
Capital International Investors2,027,232$445.2M0.09%−1,922,320−48.7%Reduced
Bank of New York Mellon Corp2,062,806$453.0M0.08%−25,982−1.2%Reduced
Deutsche Bank AG2,559,313$562.0M0.25%−127,278−4.7%Reduced
Norges Bank2,679,899$588.5M0.12%+153,719+6.1%Added
Northern Trust Corp2,908,352$638.7M0.10%−86,138−2.9%Reduced
Bank of America Corp3,098,017$680.3M0.07%+67,661+2.2%Added
Massachusetts Financial Services Co3,194,678$701.5M0.19%+45,438+1.4%Added
UBS Asset Management Americas Inc3,514,231$771.7M0.30%+755,378+27.4%Added
Geode Capital Management, LLC4,356,220$954.3M0.11%+53,868+1.3%Added
Ameriprise Financial Inc4,423,196$969.2M0.27%+1,034,106+30.5%Added
JPMorgan Chase & Co4,464,331$980.4M0.12%+252,599+6.0%Added
Clearbridge Investments, LLC5,196,730$1.14B0.78%+84,326+1.6%Added
Price T Rowe Associates Inc5,421,291$1.19B0.11%−276,956−4.9%Reduced
Wellington Management Group LLP6,518,455$1.43B0.23%+427,366+7.0%Added
Loomis Sayles & Co L P6,635,253$1.46B1.76%−370,739−5.3%Reduced
FMR LLC9,093,853$2.00B0.15%+4,216,754+86.5%Added
Alliancebernstein L.P.10,443,771$2.29B0.81%+1,374,923+15.2%Added
Capital World Investors11,520,855$2.53B0.40%+478,553+4.3%Added
State Street Corp12,356,915$2.71B0.13%+33,499+0.3%Added
Vanguard Group Inc20,155,842$4.43B0.10%−286,849−1.4%Reduced
BlackRock Inc.23,944,931$5.26B0.13%+397,036+1.7%Added
Eagle Bay Advisors LLC1––−51−98.1%Reduced
1832 Asset Management L.P.0$00.00%−84,040−100.0%Sold out
Two Sigma Investments, LP0$00.00%−959,684−100.0%Sold out
Avoro Capital Advisors LLC0$00.00%−664,000−100.0%Sold out
HealthCor Management, L.P.0$00.00%−130,290−100.0%Sold out
Worldquant Millennium Advisors LLC0$00.00%−122,737−100.0%Sold out
AMP Capital Investors Ltd0$00.00%−95,231−100.0%Sold out
CIBC World Markets Corp0$00.00%−68,765−100.0%Sold out
Beck Bode, LLC0$00.00%−53,823−100.0%Sold out
Paloma Partners Management Co0$00.00%−52,912−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−43,583−100.0%Sold out
Lombard Odier Asset Management (USA) Corp0$00.00%−41,690−100.0%Sold out
Broadleaf Partners, LLC0$00.00%−38,424−100.0%Sold out
Achmea Investment Management B.V.0$00.00%−37,930−100.0%Sold out
Tudor Investment Corp Et Al0$00.00%−29,658−100.0%Sold out
Sio Capital Management, LLC0$00.00%−25,500−100.0%Sold out
M&G Investment Management Ltd0$00.00%−21,836−100.0%Sold out
Quantbot Technologies LP0$00.00%−20,190−100.0%Sold out
American Assets Investment Management, LLC0$00.00%−20,000−100.0%Sold out
Maverick Capital LtdSuperinvestorMaverick Capital0$00.00%−18,052−100.0%Sold out
Trexquant Investment LP0$00.00%−15,061−100.0%Sold out
Prosight Management, LP0$00.00%−15,000−100.0%Sold out
Meeder Asset Management Inc0$00.00%−11,404−100.0%Sold out
Investment House LLC0$00.00%−10,795−100.0%Sold out
Atlantic Trust, LLC0$00.00%−10,459−100.0%Sold out
AlphaCentric Advisors LLC0$00.00%−10,250−100.0%Sold out
Mastrapasqua Asset Management Inc0$00.00%−10,184−100.0%Sold out
Stevens Capital Management LP0$00.00%−9,972−100.0%Sold out
Family Management Corp0$00.00%−9,758−100.0%Sold out
Pearl River Capital, LLC0$00.00%−9,672−100.0%Sold out
Blueshift Asset Management, LLC0$00.00%−9,671−100.0%Sold out
Capula Management Ltd0$00.00%−8,995−100.0%Sold out
Seven Eight Capital, LP0$00.00%−8,676−100.0%Sold out
Toroso Investments, LLC0$00.00%−8,410−100.0%Sold out
Malaga Cove Capital, LLC0$00.00%−7,905−100.0%Sold out
Dynamic Technology Lab Private Ltd0$00.00%−7,831−100.0%Sold out
MEAG MUNICH ERGO, Kapitalanlagegesellschaft mbH0$00.00%−7,177−100.0%Sold out
Virtu Financial LLC0$00.00%−6,887−100.0%Sold out
Wesbanco Bank Inc0$00.00%−6,065−100.0%Sold out
Parallax Volatility Advisers, L.P.0$00.00%−5,024−100.0%Sold out
Quantamental Technologies LLC0$00.00%−4,282−100.0%Sold out
Harvey Capital Management Inc0$00.00%−4,000−100.0%Sold out
Glenview Trust Co0$00.00%−3,890−100.0%Sold out
Duality Advisers, LP0$00.00%−3,376−100.0%Sold out
Chesley Taft & Associates LLC0$00.00%−3,154−100.0%Sold out
Fiduciary Trust Co0$00.00%−2,858−100.0%Sold out
Spirit of America Management Corp0$00.00%−2,550−100.0%Sold out
Campbell & CO Investment Adviser LLC0$00.00%−1,900−100.0%Sold out
Bridgefront Capital, LLC0$00.00%−1,831−100.0%Sold out
Columbus Macro, LLC0$00.00%−1,617−100.0%Sold out
McDonald Partners LLC0$00.00%−1,575−100.0%Sold out
Credit Capital Investments LLC0$00.00%−1,563−100.0%Sold out
Neo Ivy Capital Management0$00.00%−906−100.0%Sold out
Migdal Insurance & Financial Holdings Ltd.0$00.00%−1,401−100.0%Sold out
Davy Global Fund Management Ltd0$00.00%−1,376−100.0%Sold out
Kore Private Wealth LLC0$00.00%−1,340−100.0%Sold out
Pallas Capital Advisors LLC0$00.00%−1,247−100.0%Sold out
Parsons Capital Management Inc0$00.00%−1,268−100.0%Sold out
Zacks Investment Management0$00.00%−1,253−100.0%Sold out
Symmetry Partners, LLC0$00.00%−1,233−100.0%Sold out
New York Life Investments Alternatives0$00.00%−1,190−100.0%Sold out
Camden Capital, LLC0$00.00%−1,119−100.0%Sold out
Quilter Plc0$00.00%−1,107−100.0%Sold out
Exane Derivatives0$00.00%−1,024−100.0%Sold out
Global Retirement Partners, LLC0$00.00%−850−100.0%Sold out
CastleArk Alternatives, LLC0$00.00%−730−100.0%Sold out
US Asset Management LLC0$00.00%−542−100.0%Sold out