Silence Therapeutics plc
SLN- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001479615
No open-market purchases or sales by Silence Therapeutics plc insiders were filed in the last 90 days; 72 institutions reported holding it in 13F filings for Q2 2026, worth $236.2M in total; no superinvestor holds it.
Other share classesSLNCF
13F holders, Q4 2025
Institutional positions in Silence Therapeutics plc as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 58
- +4 vs. Q3 2025
- Shares held
- 18.1M
- −1.61M (−8.2%) vs. Q3 2025
- Total value
- $106.1M
- +$9.64M (+10.0%) vs. Q3 2025
- New holders
- 14
- 15 more added
- Sold out
- 10
- 17 more reduced
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting SLN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 72 | $236.2M |
| Q1 2026 | 56 | $102.1M |
| Q4 2025 | 58 | $106.1M |
| Q3 2025 | 54 | $96.4M |
| Q2 2025 | 55 | $108.0M |
| Q1 2025 | 59 | $60.6M |
| Q4 2024 | 65 | $168.2M |
| Q3 2024 | 69 | $493.1M |
| Q2 2024 | 71 | $502.1M |
| Q1 2024 | 64 | $588.0M |
| Q4 2023 | 34 | $343.9M |
| Q3 2023 | 28 | $187.6M |
| Q2 2023 | 29 | $101.8M |
| Q1 2023 | 29 | $110.2M |
| Q4 2022 | 27 | $275.7M |
| Q3 2022 | 29 | $183.4M |
| Q2 2022 | 25 | $116.4M |
| Q1 2022 | 26 | $218.3M |
| Q4 2021 | 22 | $246.6M |
| Q3 2021 | 7 | $39.4M |
| Q2 2021 | 6 | $56.4M |
| Q1 2021 | 6 | $55.9M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Silence Therapeutics plc; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Royal Bank of Canada | 16 | $0 | 0.00% | −1,120−98.6% | Reduced |
| Advisor Group Holdings, Inc. | 3 | $18 | 0.00% | −62,168−100.0% | Reduced |
| SageView Advisory Group, LLC | 11 | $67 | 0.00% | +11 | New |
| SBI Securities Co., Ltd. | 28 | $170 | 0.00% | −1−3.4% | Reduced |
| Rockefeller Capital Management L.P. | 45 | $274 | 0.00% | 00.0% | Unchanged |
| Steward Partners Investment Advisory, LLC | 100 | $608 | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 922 | $5.61K | 0.00% | −56−5.7% | Reduced |
| Global Retirement Partners, LLC | 1,000 | $6.08K | 0.00% | +1,000 | New |
| Parallel Advisors, LLC | 1,300 | $7.90K | 0.00% | 00.0% | Unchanged |
| Citigroup Inc | 1,621 | $9.86K | 0.00% | −152−8.6% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 2,282 | $13.9K | 0.00% | +466+25.7% | Added |
| Tower Research Capital LLC (TRC) | 2,448 | $14.9K | 0.00% | +10.0% | Added |
| Jones Financial Companies LLLP | 2,500 | $15.2K | 0.00% | 00.0% | Unchanged |
| Bank of America Corp | 2,966 | $18.0K | 0.00% | −565−16.0% | Reduced |
| Simplex Trading, LLC | 3,991 | $24.3K | 0.00% | +3,340+513.1% | Added |
| Barclays PLC | 5,065 | $30.8K | 0.00% | −2,071−29.0% | Reduced |
| JPMorgan Chase & Co | 7,942 | $48.3K | 0.00% | +176+2.3% | Added |
| GAMMA Investing LLC | 10,112 | $61.5K | 0.00% | +197+2.0% | Added |
| XTX Topco Ltd | 11,718 | $71.2K | 0.00% | +11,718 | New |
| BNP Paribas Arbitrage, SA | 12,027 | $73.1K | 0.00% | +11,427+1,904.5% | Added |
| Rhumbline Advisers | 12,999 | $79.0K | 0.00% | +7,134+121.6% | Added |
| China Universal Asset Management Co., Ltd. | 13,653 | $83.0K | 0.01% | +5,421+65.9% | Added |
| Two Sigma Advisers, LP | 15,900 | $96.7K | 0.00% | −26,700−62.7% | Reduced |
| Susquehanna International Group, LLP | 16,866 | $102.5K | 0.00% | +16,866 | New |
| Goldman Sachs Group Inc | 18,114 | $110.1K | 0.00% | −4,530−20.0% | Reduced |
| ADAR1 Capital Management, LLC | 23,643 | $143.7K | 0.01% | +5,000+26.8% | Added |
| Raymond James Financial Inc | 25,000 | $152.0K | 0.00% | +25,000 | New |
| Jane Street Group, LLC | 29,168 | $177.3K | 0.00% | +29,168 | New |
| Geode Capital Management, LLC | 29,538 | $179.6K | 0.00% | 00.0% | Unchanged |
| Qube Research & Technologies Ltd | 34,962 | $212.6K | 0.00% | +34,962 | New |
| Two Sigma Investments, LP | 39,344 | $239.2K | 0.00% | −23,903−37.8% | Reduced |
| Quadrature Capital Ltd | 54,380 | $330.6K | 0.00% | +54,380 | New |
| BlackRock, Inc. | 73,153 | $444.8K | 0.00% | +11,321+18.3% | Added |
| Opaleye Management Inc. | 78,926 | $479.9K | 0.06% | +78,926 | New |
| Point72 Asset Management, L.P. | 114,070 | $693.5K | 0.00% | +114,070 | New |
| Seven Fleet Capital Management LP | 147,600 | $897.4K | 0.61% | +147,600 | New |
| Marshall Wace, LLP | 155,680 | $946.5K | 0.00% | +72,461+87.1% | Added |
| Bank of Montreal | 160,474 | $975.7K | 0.00% | +6,692+4.4% | Added |
| HSBC Holdings PLC | 172,834 | $1.07M | 0.00% | −390.0% | Reduced |
| M28 Capital Management LP | 185,100 | $1.13M | 0.82% | 00.0% | Unchanged |
| Lombard Odier Asset Management (USA) Corp | 255,901 | $1.15M | 0.47% | −1,589,047−86.1% | Reduced |
| UBS Group AG | 207,513 | $1.26M | 0.00% | −99,850−32.5% | Reduced |
| Boothbay Fund Management, LLC | 209,088 | $1.27M | 0.03% | −70,549−25.2% | Reduced |
| Ishara Investments LP | 240,000 | $1.46M | 1.70% | +240,000 | New |
| Citadel Advisors LLC | 244,061 | $1.48M | 0.00% | +222,556+1,034.9% | Added |
| SG Americas Securities, LLC | 256,340 | $1.56M | 0.00% | −51,949−16.9% | Reduced |
| Ikarian Capital, LLC | 865,784 | $1.73M | 0.22% | −35,000−3.9% | Reduced |
| Morgan Stanley | 324,630 | $1.97M | 0.00% | −883,094−73.1% | Reduced |
| Polygon Management Ltd. | 365,369 | $2.22M | 0.47% | +365,369 | New |
| 5AM Venture Management, LLC | 476,200 | $2.90M | 0.91% | 00.0% | Unchanged |
| Millennium Management LLC | 659,592 | $4.01M | 0.00% | +361,080+121.0% | Added |
| Great Point Partners LLC | 808,032 | $4.91M | 1.59% | +808,032 | New |
| Nextech Invest, Ltd. | 952,400 | $5.79M | 0.56% | 00.0% | Unchanged |
| Vivo Capital, LLC | 1,105,454 | $6.72M | 0.43% | 00.0% | Unchanged |
| Nantahala Capital Management, LLC | 1,542,427 | $9.38M | 0.56% | +500,000+48.0% | Added |
| Redmile Group, LLC | 2,164,777 | $13.2M | 0.97% | 00.0% | Unchanged |
| Siren, L.L.C. | 2,911,438 | $17.7M | 0.53% | 00.0% | Unchanged |
| TCG Crossover Management, LLC | 3,033,560 | $18.4M | 0.61% | 00.0% | Unchanged |
| Frazier Life Sciences Management, L.P. | 0 | $0 | 0.00% | −970,130−100.0% | Sold out |
| Cantor Fitzgerald, L. P. | 0 | $0 | 0.00% | −801,306−100.0% | Sold out |
| Woodline Partners LP | 0 | $0 | 0.00% | −62,459−100.0% | Sold out |
| Virtus Investment Advisers, Inc. | 0 | $0 | 0.00% | −20,374−100.0% | Sold out |
| HRT Financial LP | 0 | $0 | 0.00% | −10,887−100.0% | Sold out |
| EHP Funds Inc. | 0 | $0 | 0.00% | −10,673−100.0% | Sold out |
| Cambridge Investment Research Advisors, Inc. | 0 | $0 | 0.00% | −10,194−100.0% | Sold out |
| Wexford Capital LP | 0 | $0 | 0.00% | −7,708−100.0% | Sold out |
| Acadian Asset Management LLC | 0 | $0 | 0.00% | −4,218−100.0% | Sold out |
| Principal Securities, Inc. | 0 | $0 | 0.00% | −17−100.0% | Sold out |