Skip to main content

Silence Therapeutics plc

SLN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001479615

No open-market purchases or sales by Silence Therapeutics plc insiders were filed in the last 90 days; 72 institutions reported holding it in 13F filings for Q2 2026, worth $236.2M in total; no superinvestor holds it.

Other share classesSLNCF

13F holders, Q1 2026

Institutional positions in Silence Therapeutics plc as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
56
−1 vs. Q4 2025
Shares held
19.9M
+1.82M (+10.1%) vs. Q4 2025
Total value
$102.1M
−$3.99M (−3.8%) vs. Q4 2025
New holders
6
24 more added
Sold out
7
11 more reduced

1 institution that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SLN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 56 institutions
Q1 2021: 6 institutionsQ2 2021: 6 institutionsQ3 2021: 7 institutionsQ4 2021: 22 institutionsQ1 2022: 26 institutionsQ2 2022: 25 institutionsQ3 2022: 29 institutionsQ4 2022: 27 institutionsQ1 2023: 29 institutionsQ2 2023: 29 institutionsQ3 2023: 28 institutionsQ4 2023: 34 institutionsQ1 2024: 64 institutionsQ2 2024: 71 institutionsQ3 2024: 69 institutionsQ4 2024: 65 institutionsQ1 2025: 59 institutionsQ2 2025: 55 institutionsQ3 2025: 54 institutionsQ4 2025: 58 institutionsQ1 2026: 56 institutionsQ2 2026: 72 institutions
Value heldQ1 2026: $102.1M
Q1 2021: $55.9MQ2 2021: $56.4MQ3 2021: $39.4MQ4 2021: $246.6MQ1 2022: $218.3MQ2 2022: $116.4MQ3 2022: $183.4MQ4 2022: $275.7MQ1 2023: $110.2MQ2 2023: $101.8MQ3 2023: $187.6MQ4 2023: $343.9MQ1 2024: $588.0MQ2 2024: $502.1MQ3 2024: $493.1MQ4 2024: $168.2MQ1 2025: $60.6MQ2 2025: $108.0MQ3 2025: $96.4MQ4 2025: $106.1MQ1 2026: $102.1MQ2 2026: $236.2M
Institutions holding SLN and their total value by quarter
QuarterHoldersValue
Q2 202672$236.2M
Q1 202656$102.1M
Q4 202558$106.1M
Q3 202554$96.4M
Q2 202555$108.0M
Q1 202559$60.6M
Q4 202465$168.2M
Q3 202469$493.1M
Q2 202471$502.1M
Q1 202464$588.0M
Q4 202334$343.9M
Q3 202328$187.6M
Q2 202329$101.8M
Q1 202329$110.2M
Q4 202227$275.7M
Q3 202229$183.4M
Q2 202225$116.4M
Q1 202226$218.3M
Q4 202122$246.6M
Q3 20217$39.4M
Q2 20216$56.4M
Q1 20216$55.9M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Silence Therapeutics plc; share changes are against Q4 2025.

Institutions holding SLN in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
TCG Crossover Management, LLC3,033,560$16.0M0.46%00.0%Unchanged
Siren, L.L.C.2,911,438$15.3M0.43%00.0%Unchanged
Redmile Group, LLC2,164,777$11.4M0.76%00.0%Unchanged
Nantahala Capital Management, LLC2,146,731$11.3M0.71%+604,304+39.2%Added
Citadel Advisors LLC1,234,807$6.51M0.00%+990,746+405.9%Added
Millennium Management LLC1,074,191$5.66M0.00%+414,599+62.9%Added
Great Point Partners LLC1,020,489$5.38M1.32%+212,457+26.3%Added
Nextech Invest, Ltd.952,400$5.02M0.35%00.0%Unchanged
Polygon Management Ltd.630,161$3.32M0.65%+264,792+72.5%Added
5AM Venture Management, LLC476,200$2.51M0.70%00.0%Unchanged
Ikarian Capital, LLC865,784$1.73M0.25%00.0%Unchanged
Jones Hill Capital LP301,604$1.59M0.34%+301,604New
SG Americas Securities, LLC286,698$1.51M0.00%+30,358+11.8%Added
UBS Group AG246,937$1.30M0.00%+39,424+19.0%Added
Boothbay Fund Management, LLC209,088$1.10M0.03%00.0%Unchanged
BlackRock, Inc.204,777$1.08M0.00%+131,624+179.9%Added
Bank of Montreal202,901$1.07M0.00%+42,427+26.4%Added
ADAR1 Capital Management, LLC172,157$907.3K0.05%+148,514+628.2%Added
Marshall Wace, LLP169,616$893.9K0.00%+13,936+9.0%Added
Seven Fleet Capital Management LP156,759$826.1K0.26%+9,159+6.2%Added
BNP Paribas Arbitrage, SA147,668$778.2K0.00%+135,641+1,127.8%Added
Ishara Investments LP140,500$740.4K0.75%−99,500−41.5%Reduced
HSBC Holdings PLC122,834$640.0K0.00%−50,000−28.9%Reduced
Point72 Asset Management, L.P.119,711$630.9K0.00%+5,641+4.9%Added
Susquehanna International Group, LLP115,281$607.5K0.00%+98,415+583.5%Added
XTX Topco Ltd106,002$558.6K0.01%+94,284+804.6%Added
Qube Research & Technologies Ltd104,555$551.0K0.00%+69,593+199.1%Added
M28 Capital Management LP101,203$533.3K0.99%−83,897−45.3%Reduced
Jane Street Group, LLC100,927$531.9K0.00%+71,759+246.0%Added
Squarepoint Ops LLC89,469$471.5K0.00%+89,469New
Morgan Stanley65,486$345.1K0.00%−259,144−79.8%Reduced
Goldman Sachs Group Inc52,511$276.7K0.00%+34,397+189.9%Added
Bank of America Corp29,773$156.9K0.00%+26,807+903.8%Added
Geode Capital Management, LLC29,538$155.7K0.00%00.0%Unchanged
Raymond James Financial Inc25,000$131.8K0.00%00.0%Unchanged
Two Sigma Investments, LP16,203$85.4K0.00%−23,141−58.8%Reduced
Rhumbline Advisers13,935$73.4K0.00%+936+7.2%Added
HRT Financial LP11,994$63.0K0.00%+11,994New
Dynamic Technology Lab Private Ltd10,490$55.3K0.01%+10,490New
GAMMA Investing LLC9,365$49.4K0.00%−747−7.4%Reduced
China Universal Asset Management Co., Ltd.8,335$43.9K0.00%−5,318−39.0%Reduced
JPMorgan Chase & Co7,636$38.0K0.00%−306−3.9%Reduced
Acadian Asset Management LLC4,818$25.0K0.00%+4,818New
Barclays PLC2,937$15.5K0.00%−2,128−42.0%Reduced
Mirae Asset Global Investments Co., Ltd.2,450$12.9K0.00%+168+7.4%Added
Jones Financial Companies LLLP2,500$12.3K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)2,313$12.2K0.00%−135−5.5%Reduced
Citigroup Inc1,835$9.67K0.00%+214+13.2%Added
Parallel Advisors, LLC1,300$6.85K0.00%00.0%Unchanged
GF Fund Management Co. Ltd.1,047$5.52K0.00%+125+13.6%Added
Simplex Trading, LLC612$3.23K0.00%−3,379−84.7%Reduced
Steward Partners Investment Advisory, LLC100$5270.00%00.0%Unchanged
Rockefeller Capital Management L.P.45$2370.00%00.0%Unchanged
SBI Securities Co., Ltd.28$1480.00%00.0%Unchanged
Caitong International Asset Management Co., Ltd3$160.00%+3New
Royal Bank of Canada16$00.00%00.0%Unchanged
Vivo Capital, LLC0$00.00%−1,105,454−100.0%Sold out
Lombard Odier Asset Management (USA) Corp0$00.00%−255,901−100.0%Sold out
Opaleye Management Inc.0$00.00%−78,926−100.0%Sold out
Quadrature Capital Ltd0$00.00%−54,380−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−15,900−100.0%Sold out
SageView Advisory Group, LLC0$00.00%−11−100.0%Sold out
Advisor Group Holdings, Inc.0$00.00%−3−100.0%Sold out
Global Retirement Partners, LLC––––Not filed