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Silence Therapeutics plc

SLN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001479615

No open-market purchases or sales by Silence Therapeutics plc insiders were filed in the last 90 days; 72 institutions reported holding it in 13F filings for Q2 2026, worth $236.2M in total; no superinvestor holds it.

Other share classesSLNCF

13F holders, Q2 2024

Institutional positions in Silence Therapeutics plc as of Jun 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
71
+7 vs. Q1 2024
Shares held
27.2M
−496.1K (−1.8%) vs. Q1 2024
Total value
$502.1M
−$85.9M (−14.6%) vs. Q1 2024
New holders
12
22 more added
Sold out
5
19 more reduced

Compare with Q1 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SLN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2024: 71 institutions
Q1 2021: 6 institutionsQ2 2021: 6 institutionsQ3 2021: 7 institutionsQ4 2021: 22 institutionsQ1 2022: 26 institutionsQ2 2022: 25 institutionsQ3 2022: 29 institutionsQ4 2022: 27 institutionsQ1 2023: 29 institutionsQ2 2023: 29 institutionsQ3 2023: 28 institutionsQ4 2023: 34 institutionsQ1 2024: 64 institutionsQ2 2024: 71 institutionsQ3 2024: 69 institutionsQ4 2024: 65 institutionsQ1 2025: 59 institutionsQ2 2025: 55 institutionsQ3 2025: 54 institutionsQ4 2025: 58 institutionsQ1 2026: 56 institutionsQ2 2026: 72 institutions
Value heldQ2 2024: $502.1M
Q1 2021: $55.9MQ2 2021: $56.4MQ3 2021: $39.4MQ4 2021: $246.6MQ1 2022: $218.3MQ2 2022: $116.4MQ3 2022: $183.4MQ4 2022: $275.7MQ1 2023: $110.2MQ2 2023: $101.8MQ3 2023: $187.6MQ4 2023: $343.9MQ1 2024: $588.0MQ2 2024: $502.1MQ3 2024: $493.1MQ4 2024: $168.2MQ1 2025: $60.6MQ2 2025: $108.0MQ3 2025: $96.4MQ4 2025: $106.1MQ1 2026: $102.1MQ2 2026: $236.2M
Institutions holding SLN and their total value by quarter
QuarterHoldersValue
Q2 202672$236.2M
Q1 202656$102.1M
Q4 202558$106.1M
Q3 202554$96.4M
Q2 202555$108.0M
Q1 202559$60.6M
Q4 202465$168.2M
Q3 202469$493.1M
Q2 202471$502.1M
Q1 202464$588.0M
Q4 202334$343.9M
Q3 202328$187.6M
Q2 202329$101.8M
Q1 202329$110.2M
Q4 202227$275.7M
Q3 202229$183.4M
Q2 202225$116.4M
Q1 202226$218.3M
Q4 202122$246.6M
Q3 20217$39.4M
Q2 20216$56.4M
Q1 20216$55.9M

Institutions, Q2 2024

Shares, value and share of portfolio for each institution holding Silence Therapeutics plc; share changes are against Q1 2024.

Institutions holding SLN in Q2 2024
InstitutionSharesValue% of portfolioChange in sharesAction
TCG Crossover Management, LLC3,295,350$62.6M6.53%00.0%Unchanged
Artal Group S.A.2,779,619$52.8M1.36%00.0%Unchanged
Redmile Group, LLC2,014,296$38.3M2.31%−13,373−0.7%Reduced
Lombard Odier Asset Management (USA) Corp2,405,998$36.8M13.89%+17,086+0.7%Added
Logos Global Management LP1,476,061$28.0M3.23%00.0%Unchanged
Deep Track Capital, LP1,359,745$25.8M0.77%−284,136−17.3%Reduced
Frazier Life Sciences Management, L.P.1,148,591$21.8M1.02%00.0%Unchanged
Vivo Capital, LLC1,105,454$21.0M1.94%00.0%Unchanged
Nextech Invest AG952,400$18.1M3.04%00.0%Unchanged
Polar Capital Holdings Plc940,164$17.9M0.11%+440,164+88.0%Added
Janus Henderson Group PLC818,978$15.6M0.01%+193,114+30.9%Added
Millennium Management LLC782,941$14.9M0.01%+373,523+91.2%Added
Cormorant Asset Management, LP625,000$11.9M0.69%00.0%Unchanged
Adage Capital Partners GP, L.L.C.600,000$11.4M0.02%00.0%Unchanged
First Turn Management, LLC537,338$10.2M1.66%+537,338New
Aquilo Capital Management, LLC500,214$9.50M9.16%−74,000−12.9%Reduced
5AM Venture Management, LLC476,200$9.05M2.02%00.0%Unchanged
Duquesne Family Office LLCSuperinvestorDuquesne Family Office387,400$7.36M0.26%00.0%Unchanged
Mangrove Partners385,408$7.32M0.66%00.0%Unchanged
SG Americas Securities, LLC343,196$6.52M0.04%+336,196+4,802.8%Added
Morgan Stanley303,993$5.78M0.00%+61,223+25.2%Added
Parkman Healthcare Partners LLC289,841$5.51M0.75%+45,370+18.6%Added
Cantor Fitzgerald, L. P.247,966$4.71M0.95%+144,483+139.6%Added
Hudson Bay Capital Management LP208,064$3.95M0.03%−68,526−24.8%Reduced
Nantahala Capital Management, LLC200,000$3.80M0.38%00.0%Unchanged
M28 Capital Management LP185,100$3.52M4.56%−114,300−38.2%Reduced
HSBC Holdings PLC177,834$3.41M0.00%00.0%Unchanged
Octagon Capital Advisors LP176,000$3.34M0.55%−139,000−44.1%Reduced
Ikarian Capital, LLC506,665$3.29M1.03%+506,665New
Nicholas Investment Partners, LP150,480$2.86M0.30%+150,480New
Marshall Wace, LLP149,397$2.84M0.00%+10,206+7.3%Added
Boothbay Fund Management, LLC146,852$2.79M0.09%+19,628+15.4%Added
Point72 Asset Management, L.P.146,500$2.78M0.01%+138,300+1,686.6%Added
StemPoint Capital LP124,866$2.37M0.70%+124,866New
Citadel Advisors LLC116,760$2.22M0.00%+74,078+173.6%Added
BIT Capital GmbH101,235$1.92M0.17%+12,235+13.7%Added
Two Sigma Investments, LP99,107$1.88M0.00%−8,105−7.6%Reduced
Woodline Partners LP90,862$1.73M0.02%−147,518−61.9%Reduced
UBS Oconnor LLC76,840$1.46M0.04%+4,617+6.4%Added
Two Sigma Advisers, LP76,200$1.45M0.00%−1,200−1.6%Reduced
Schonfeld Strategic Advisors LLC75,037$1.43M0.01%−57,963−43.6%Reduced
Walleye Capital LLC74,220$1.41M0.01%−17,599−19.2%Reduced
UBS Group AG73,806$1.40M0.00%+1,888+2.6%Added
Citigroup Inc58,333$1.11M0.00%00.0%Unchanged
Artia Global Partners LP52,476$997.0K0.26%00.0%Unchanged
ADAR1 Capital Management, LLC40,290$765.5K0.15%+200+0.5%Added
Renaissance Technologies LLC39,100$742.9K0.00%−64,800−62.4%Reduced
NEOS Investment Management LLC37,164$706.1K0.03%+25,508+218.8%Added
Geode Capital Management, LLC29,417$558.9K0.00%+6,990+31.2%Added
Blair William & Co25,432$483.2K0.00%00.0%Unchanged
New York State Common Retirement Fund24,066$457.3K0.00%+24,066New
Trexquant Investment LP21,803$414.3K0.01%+756+3.6%Added
Legato Capital Management LLC19,800$376.2K0.05%+19,800New
Rathbone Brothers plc18,421$350.0K0.00%−1,485−7.5%Reduced
Y-Intercept (Hong Kong) Ltd17,155$325.9K0.02%+17,155New
Goldman Sachs Group Inc16,256$308.9K0.00%−5,483−25.2%Reduced
Custom Index Systems, LLC14,836$281.9K0.16%+14,836New
Advisor Group Holdings, Inc.12,841$244.0K0.00%+1,919+17.6%Added
Jump Financial, LLC12,342$234.5K0.00%−6,458−34.4%Reduced
Bank of America Corp10,012$190.2K0.00%−1,980−16.5%Reduced
Cubist Systematic Strategies, LLC9,438$179.3K0.00%−26,843−74.0%Reduced
Vestcor Inc8,800$167.0K0.01%+8,800New
Quarry LP6,000$114.0K0.05%+6,000New
Barclays PLC5,570$105.8K0.00%00.0%Unchanged
Advisors Preferred, LLC5,315$99.6K0.02%+4,206+379.3%Added
Royal Bank of Canada4,716$89.0K0.00%+4,716New
Virtus ETF Advisers LLC4,591$87.2K0.04%+4,591New
GAMMA Investing LLC859$16.3K0.00%−17−1.9%Reduced
Rhumbline Advisers469$8.91K0.00%+454+3,026.7%Added
Steward Partners Investment Advisory, LLC100$1.90K0.00%00.0%Unchanged
Lazard Asset Management LLC60$1.00K0.00%−1,355−95.8%Reduced
Lombard Odier Asset Management (Europe) Ltd0$00.00%−2,238,039−100.0%Sold out
Lynx1 Capital Management LP0$00.00%−526,642−100.0%Sold out
Shay Capital LLC0$00.00%−15,150−100.0%Sold out
JPMorgan Chase & Co0$00.00%−9,610−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−3,942−100.0%Sold out