Skip to main content

Silence Therapeutics plc

SLN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001479615

No open-market purchases or sales by Silence Therapeutics plc insiders were filed in the last 90 days; 72 institutions reported holding it in 13F filings for Q2 2026, worth $253.5M in total; no superinvestor holds it.

Other share classesSLNCF

13F holders, Q2 2026

Institutional positions in Silence Therapeutics plc as of Jun 30, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
72
+16 vs. Q1 2026
Shares held
23.6M
+3.67M (+18.5%) vs. Q1 2026
Total value
$253.5M
+$151.4M (+148.3%) vs. Q1 2026
New holders
20
22 more added
Sold out
4
18 more reduced

Compare with Q1 2026: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SLN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2026: 72 institutions
Q1 2021: 6 institutionsQ2 2021: 6 institutionsQ3 2021: 7 institutionsQ4 2021: 22 institutionsQ1 2022: 26 institutionsQ2 2022: 25 institutionsQ3 2022: 29 institutionsQ4 2022: 27 institutionsQ1 2023: 29 institutionsQ2 2023: 29 institutionsQ3 2023: 28 institutionsQ4 2023: 34 institutionsQ1 2024: 64 institutionsQ2 2024: 71 institutionsQ3 2024: 69 institutionsQ4 2024: 65 institutionsQ1 2025: 59 institutionsQ2 2025: 55 institutionsQ3 2025: 54 institutionsQ4 2025: 58 institutionsQ1 2026: 56 institutionsQ2 2026: 72 institutions
Value heldQ2 2026: $253.5M
Q1 2021: $55.9MQ2 2021: $56.4MQ3 2021: $39.4MQ4 2021: $246.6MQ1 2022: $230.8MQ2 2022: $124.0MQ3 2022: $189.8MQ4 2022: $275.7MQ1 2023: $110.2MQ2 2023: $101.8MQ3 2023: $187.6MQ4 2023: $345.0MQ1 2024: $598.7MQ2 2024: $534.1MQ3 2024: $493.1MQ4 2024: $168.2MQ1 2025: $60.6MQ2 2025: $108.1MQ3 2025: $96.5MQ4 2025: $107.1MQ1 2026: $102.1MQ2 2026: $253.5M
Institutions holding SLN and their total value by quarter
QuarterHoldersValue
Q2 202672$253.5M
Q1 202656$102.1M
Q4 202558$107.1M
Q3 202554$96.5M
Q2 202555$108.1M
Q1 202559$60.6M
Q4 202465$168.2M
Q3 202469$493.1M
Q2 202471$534.1M
Q1 202464$598.7M
Q4 202334$345.0M
Q3 202328$187.6M
Q2 202329$101.8M
Q1 202329$110.2M
Q4 202227$275.7M
Q3 202229$189.8M
Q2 202225$124.0M
Q1 202226$230.8M
Q4 202122$246.6M
Q3 20217$39.4M
Q2 20216$56.4M
Q1 20216$55.9M

Institutions, Q2 2026

Shares, value and share of portfolio for each institution holding Silence Therapeutics plc; share changes are against Q1 2026.

Institutions holding SLN in Q2 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Siren, L.L.C.3,311,438$36.4M0.74%+400,000+13.7%Added
TCG Crossover Management, LLC3,033,560$33.3M0.80%00.0%Unchanged
Nantahala Capital Management, LLC2,693,462$29.6M0.90%+546,731+25.5%Added
Redmile Group, LLC2,164,777$23.8M1.60%00.0%Unchanged
Citadel Advisors LLC1,329,625$14.6M0.01%+94,818+7.7%Added
Nextech Invest, Ltd.952,400$10.5M0.50%00.0%Unchanged
Millennium Management LLC909,279$9.98M0.01%−164,912−15.4%Reduced
Polygon Management Ltd.764,256$8.39M1.37%+134,095+21.3%Added
Soleus Capital Management, L.P.630,000$6.92M0.24%+630,000New
Balyasny Asset Management LLC610,980$6.71M0.01%+610,980New
5AM Venture Management, LLC476,200$5.23M1.82%00.0%Unchanged
Great Point Partners LLC450,000$4.94M1.16%−570,489−55.9%Reduced
Morgan Stanley403,172$4.43M0.00%+337,686+515.7%Added
Ameriprise Financial Inc370,052$4.06M0.00%+370,052New
Jane Street Group, LLC369,151$4.05M0.00%+268,224+265.8%Added
ADAR1 Capital Management, LLC338,373$3.72M0.17%+166,216+96.5%Added
SummitTX Capital, L.P.326,648$3.59M0.09%+326,648New
Schonfeld Strategic Advisors LLC269,348$2.96M0.02%+269,348New
UBS Group AG243,152$2.67M0.00%−3,785−1.5%Reduced
Ishara Investments LP55,350$2.43M1.79%−85,150−60.6%Reduced
BlackRock, Inc.219,917$2.41M0.00%+15,140+7.4%Added
Bank of Montreal201,734$2.22M0.00%−1,167−0.6%Reduced
Boothbay Fund Management, LLC198,347$2.18M0.04%−10,741−5.1%Reduced
Propel Bio Management, LLC191,733$2.11M1.10%+191,733New
Susquehanna International Group, LLP184,519$2.03M0.00%+69,238+60.1%Added
Fred Alger Management, LLC177,000$1.94M0.01%+177,000New
Ikarian Capital, LLC830,784$1.83M0.30%−35,000−4.0%Reduced
Qube Research & Technologies Ltd163,945$1.80M0.00%+59,390+56.8%Added
Caption Management, LLC162,476$1.78M0.06%+162,476New
BNP Paribas Arbitrage, SA158,950$1.75M0.00%+11,282+7.6%Added
Goldman Sachs Group Inc155,929$1.71M0.00%+103,418+196.9%Added
Two Sigma Investments, LP121,004$1.33M0.00%+104,801+646.8%Added
HSBC Holdings PLC122,834$1.32M0.00%00.0%Unchanged
Quadrature Capital Ltd118,129$1.30M0.01%+118,129New
Squarepoint Ops LLC115,918$1.27M0.00%+26,449+29.6%Added
XTX Topco Ltd107,579$1.18M0.02%+1,577+1.5%Added
M28 Capital Management LP101,203$1.11M2.36%00.0%Unchanged
Marshall Wace, LLP72,039$791.0K0.00%−97,577−57.5%Reduced
Birchview Capital, LP71,218$782.0K0.37%+71,218New
Seven Fleet Capital Management LP60,107$660.0K0.11%−96,652−61.7%Reduced
HRT Financial LP30,748$337.0K0.00%+18,754+156.4%Added
Geode Capital Management, LLC29,538$324.3K0.00%00.0%Unchanged
Virtu Financial LLC25,641$282.0K0.01%+25,641New
Bank of America Corp25,280$277.6K0.00%−4,493−15.1%Reduced
Trexquant Investment LP23,842$261.8K0.00%+23,842New
Verdad Advisers, LP20,400$224.0K0.21%+20,400New
Scientech Research LLC19,133$210.1K0.17%+19,133New
Renaissance Technologies LLC16,930$185.9K0.00%+16,930New
Arrowpoint Investment Partners (Singapore) Pte. Ltd.16,334$179.3K0.05%+16,334New
Persistent Asset Partners Ltd15,170$166.6K0.05%+15,170New
Raymond James Financial Inc15,000$164.7K0.00%−10,000−40.0%Reduced
Rhumbline Advisers13,815$151.7K0.00%−120−0.9%Reduced
Citigroup Inc13,217$145.1K0.00%+11,382+620.3%Added
Axq Capital, LP12,566$138.0K0.02%+12,566New
SG Americas Securities, LLC12,056$132.0K0.00%−274,642−95.8%Reduced
Acadian Asset Management LLC11,836$129.0K0.00%+7,018+145.7%Added
GAMMA Investing LLC11,063$121.5K0.00%+1,698+18.1%Added
CenterBook Partners LP10,416$114.4K0.01%+10,416New
China Universal Asset Management Co., Ltd.7,475$82.1K0.00%−860−10.3%Reduced
JPMorgan Chase & Co3,863$41.7K0.00%−3,773−49.4%Reduced
Barclays PLC3,418$37.5K0.00%+481+16.4%Added
Jones Financial Companies LLLP2,500$25.4K0.00%00.0%Unchanged
Mirae Asset Global Investments Co., Ltd.2,101$23.1K0.00%−349−14.2%Reduced
Tower Research Capital LLC (TRC)1,639$18.0K0.00%−674−29.1%Reduced
Parallel Advisors, LLC1,300$14.3K0.00%00.0%Unchanged
Rialto Wealth Management, LLC1,021$11.2K0.00%+1,021New
GF Fund Management Co. Ltd.975$10.7K0.00%−72−6.9%Reduced
Steward Partners Investment Advisory, LLC100$1.10K0.00%00.0%Unchanged
Rockefeller Capital Management L.P.45$4940.00%00.0%Unchanged
Caitong International Asset Management Co., Ltd41$4500.00%+38+1,266.7%Added
SBI Securities Co., Ltd.28$3070.00%00.0%Unchanged
Royal Bank of Canada26$00.00%+10+62.5%Added
Jones Hill Capital LP0$00.00%−301,604−100.0%Sold out
Point72 Asset Management, L.P.0$00.00%−119,711−100.0%Sold out
Dynamic Technology Lab Private Ltd0$00.00%−10,490−100.0%Sold out
Simplex Trading, LLC0$00.00%−612−100.0%Sold out