Silence Therapeutics plc
SLN- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001479615
No open-market purchases or sales by Silence Therapeutics plc insiders were filed in the last 90 days; 72 institutions reported holding it in 13F filings for Q2 2026, worth $236.2M in total; no superinvestor holds it.
Other share classesSLNCF
13F holders, Q4 2024
Institutional positions in Silence Therapeutics plc as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 65
- −4 vs. Q3 2024
- Shares held
- 24.8M
- −3.38M (−12.0%) vs. Q3 2024
- Total value
- $168.2M
- −$325.0M (−65.9%) vs. Q3 2024
- New holders
- 16
- 24 more added
- Sold out
- 20
- 13 more reduced
Compare with Q3 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting SLN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 72 | $236.2M |
| Q1 2026 | 56 | $102.1M |
| Q4 2025 | 58 | $106.1M |
| Q3 2025 | 54 | $96.4M |
| Q2 2025 | 55 | $108.0M |
| Q1 2025 | 59 | $60.6M |
| Q4 2024 | 65 | $168.2M |
| Q3 2024 | 69 | $493.1M |
| Q2 2024 | 71 | $502.1M |
| Q1 2024 | 64 | $588.0M |
| Q4 2023 | 34 | $343.9M |
| Q3 2023 | 28 | $187.6M |
| Q2 2023 | 29 | $101.8M |
| Q1 2023 | 29 | $110.2M |
| Q4 2022 | 27 | $275.7M |
| Q3 2022 | 29 | $183.4M |
| Q2 2022 | 25 | $116.4M |
| Q1 2022 | 26 | $218.3M |
| Q4 2021 | 22 | $246.6M |
| Q3 2021 | 7 | $39.4M |
| Q2 2021 | 6 | $56.4M |
| Q1 2021 | 6 | $55.9M |
Institutions, Q4 2024
Shares, value and share of portfolio for each institution holding Silence Therapeutics plc; share changes are against Q3 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| TCG Crossover Management, LLC | 3,033,560 | $20.9M | 2.04% | 00.0% | Unchanged |
| Siren, L.L.C. | 2,831,770 | $19.5M | 0.86% | 00.0% | Unchanged |
| Redmile Group, LLC | 2,399,317 | $16.5M | 1.15% | +500,000+26.3% | Added |
| Morgan Stanley | 1,663,068 | $11.4M | 0.00% | +941,651+130.5% | Added |
| Lombard Odier Asset Management (USA) Corp | 1,856,023 | $10.2M | 3.92% | −808,054−30.3% | Reduced |
| Frazier Life Sciences Management, L.P. | 1,148,591 | $7.90M | 0.33% | 00.0% | Unchanged |
| Vivo Capital, LLC | 1,105,454 | $7.61M | 0.85% | 00.0% | Unchanged |
| Nantahala Capital Management, LLC | 1,049,676 | $7.22M | 0.51% | +849,676+424.8% | Added |
| Nextech Invest AG | 952,400 | $6.55M | 1.06% | 00.0% | Unchanged |
| Eventide Asset Management, LLC | 640,000 | $4.40M | 0.08% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 633,100 | $4.36M | 0.01% | +165,300+35.3% | Added |
| Cantor Fitzgerald, L. P. | 539,726 | $3.71M | 0.14% | +205,534+61.5% | Added |
| Bank of America Corp | 499,066 | $3.43M | 0.00% | +498,032+48,165.6% | Added |
| Woodline Partners LP | 498,732 | $3.43M | 0.02% | +91,829+22.6% | Added |
| Parkman Healthcare Partners LLC | 491,080 | $3.38M | 0.45% | −6,790−1.4% | Reduced |
| Marshall Wace, LLP | 488,889 | $3.36M | 0.00% | +320,472+190.3% | Added |
| 5AM Venture Management, LLC | 476,200 | $3.28M | 0.78% | 00.0% | Unchanged |
| Millennium Management LLC | 473,552 | $3.26M | 0.00% | −636,678−57.3% | Reduced |
| Saturn V Capital Management LLC | 395,024 | $2.72M | 1.06% | −86,103−17.9% | Reduced |
| Aquilo Capital Management, LLC | 367,214 | $2.53M | 4.33% | +50,000+15.8% | Added |
| UBS Group AG | 356,071 | $2.45M | 0.00% | +285,410+403.9% | Added |
| Boothbay Fund Management, LLC | 351,527 | $2.42M | 0.08% | +180,372+105.4% | Added |
| SG Americas Securities, LLC | 317,628 | $2.19M | 0.01% | −25,562−7.4% | Reduced |
| Citadel Advisors LLC | 282,737 | $1.95M | 0.00% | −153,960−35.3% | Reduced |
| BlackRock, Inc. | 211,507 | $1.46M | 0.00% | +211,507 | New |
| Integral Health Asset Management, LLC | 200,000 | $1.38M | 0.12% | +200,000 | New |
| M28 Capital Management LP | 185,100 | $1.27M | 1.25% | 00.0% | Unchanged |
| HSBC Holdings PLC | 172,834 | $1.19M | 0.00% | −5,000−2.8% | Reduced |
| Two Sigma Investments, LP | 142,052 | $977.3K | 0.00% | −27,340−16.1% | Reduced |
| UBS Oconnor LLC | 128,990 | $887.5K | 0.02% | +43,289+50.5% | Added |
| Schonfeld Strategic Advisors LLC | 123,200 | $847.6K | 0.01% | −42,800−25.8% | Reduced |
| Cubist Systematic Strategies, LLC | 106,320 | $731.5K | 0.01% | +60,015+129.6% | Added |
| Two Sigma Advisers, LP | 98,800 | $679.7K | 0.00% | +15,500+18.6% | Added |
| Bank of Montreal | 65,007 | $447.2K | 0.00% | −252−0.4% | Reduced |
| Trexquant Investment LP | 63,663 | $438.0K | 0.01% | +63,663 | New |
| Citigroup Inc | 60,502 | $416.3K | 0.00% | +2,169+3.7% | Added |
| Qube Research & Technologies Ltd | 54,746 | $376.7K | 0.00% | +35,550+185.2% | Added |
| Advisor Group Holdings, Inc. | 40,867 | $281.0K | 0.00% | +27,708+210.6% | Added |
| Goldman Sachs Group Inc | 36,885 | $253.8K | 0.00% | +6,253+20.4% | Added |
| Walleye Capital LLC | 36,397 | $250.4K | 0.00% | +36,397 | New |
| Geode Capital Management, LLC | 29,417 | $202.4K | 0.00% | 00.0% | Unchanged |
| Verition Fund Management LLC | 24,123 | $166.0K | 0.00% | +12,733+111.8% | Added |
| Y-Intercept (Hong Kong) Ltd | 21,217 | $146.0K | 0.01% | +139+0.7% | Added |
| Commonwealth of Pennsylvania Public School Empls Retrmt Sys | 19,467 | $133.9K | 0.00% | +19,467 | New |
| Acadian Asset Management LLC | 19,467 | $133.0K | 0.00% | +19,467 | New |
| Rathbone Brothers plc | 18,421 | $126.7K | 0.00% | 00.0% | Unchanged |
| ADAR1 Capital Management, LLC | 18,000 | $123.8K | 0.03% | −22,290−55.3% | Reduced |
| FNY Investment Advisers, LLC | 17,515 | $120.0K | 0.06% | +17,515 | New |
| Ameriprise Financial Inc | 16,360 | $112.6K | 0.00% | +16,360 | New |
| Custom Index Systems, LLC | 11,861 | $81.6K | 0.04% | −2,554−17.7% | Reduced |
| Virtus ETF Advisers LLC | 10,772 | $74.1K | 0.03% | +6,098+130.5% | Added |
| China Universal Asset Management Co., Ltd. | 9,963 | $68.5K | 0.01% | +9,963 | New |
| Barclays PLC | 6,126 | $42.1K | 0.00% | +2,793+83.8% | Added |
| GAMMA Investing LLC | 6,092 | $41.9K | 0.00% | +5,233+609.2% | Added |
| JPMorgan Chase & Co | 3,793 | $26.1K | 0.00% | +3,793 | New |
| BNP Paribas Arbitrage, SA | 1,784 | $12.3K | 0.00% | +1,784 | New |
| Mirae Asset Global Investments Co., Ltd. | 1,566 | $11.1K | 0.00% | +1,566 | New |
| Royal Bank of Canada | 1,515 | $10.0K | 0.00% | −426−21.9% | Reduced |
| GF Fund Management Co. Ltd. | 987 | $6.79K | 0.00% | +987 | New |
| Rhumbline Advisers | 841 | $5.78K | 0.00% | +87+11.5% | Added |
| Tower Research Capital LLC (TRC) | 632 | $4.35K | 0.00% | +632 | New |
| Steward Partners Investment Advisory, LLC | 100 | $688 | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 28 | $193 | 0.00% | +28 | New |
| Wells Fargo & Company | 19 | $131 | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 51 | $0 | 0.00% | +51 | New |
| Janus Henderson Group PLC | 0 | $0 | 0.00% | −1,087,228−100.0% | Sold out |
| Polar Capital Holdings Plc | 0 | $0 | 0.00% | −1,000,000−100.0% | Sold out |
| Deep Track Capital, LP | 0 | $0 | 0.00% | −1,000,000−100.0% | Sold out |
| Cormorant Asset Management, LP | 0 | $0 | 0.00% | −400,000−100.0% | Sold out |
| Duquesne Family Office LLCSuperinvestorDuquesne Family Office | 0 | $0 | 0.00% | −387,400−100.0% | Sold out |
| Mangrove Partners | 0 | $0 | 0.00% | −385,408−100.0% | Sold out |
| ExodusPoint Capital Management, LP | 0 | $0 | 0.00% | −338,681−100.0% | Sold out |
| Adage Capital Partners GP, L.L.C. | 0 | $0 | 0.00% | −320,000−100.0% | Sold out |
| Soleus Capital Management, L.P. | 0 | $0 | 0.00% | −260,000−100.0% | Sold out |
| Price T Rowe Associates Inc | 0 | $0 | 0.00% | −228,644−100.0% | Sold out |
| Logos Global Management LP | 0 | $0 | 0.00% | −200,000−100.0% | Sold out |
| Ikarian Capital, LLC | 0 | $0 | 0.00% | −587,343−100.0% | Sold out |
| BIT Capital GmbH | 0 | $0 | 0.00% | −92,429−100.0% | Sold out |
| Artia Global Partners LP | 0 | $0 | 0.00% | −52,476−100.0% | Sold out |
| NEOS Investment Management LLC | 0 | $0 | 0.00% | −51,712−100.0% | Sold out |
| TD Asset Management Inc | 0 | $0 | 0.00% | −30,600−100.0% | Sold out |
| Blair William & Co | 0 | $0 | 0.00% | −20,000−100.0% | Sold out |
| Manufacturers Life Insurance Company, The | 0 | $0 | 0.00% | −17,490−100.0% | Sold out |
| Vestcor Inc | 0 | $0 | 0.00% | −8,800−100.0% | Sold out |
| Values First Advisors, Inc. | 0 | $0 | 0.00% | −3,091−100.0% | Sold out |