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Silence Therapeutics plc

SLN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001479615

No open-market purchases or sales by Silence Therapeutics plc insiders were filed in the last 90 days; 72 institutions reported holding it in 13F filings for Q2 2026, worth $236.2M in total; no superinvestor holds it.

Other share classesSLNCF

13F holders, Q3 2024

Institutional positions in Silence Therapeutics plc as of Sep 30, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
69
−2 vs. Q2 2024
Shares held
28.2M
+969.8K (+3.6%) vs. Q2 2024
Total value
$493.1M
−$8.96M (−1.8%) vs. Q2 2024
New holders
13
24 more added
Sold out
15
15 more reduced

Compare with Q2 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SLN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2024: 69 institutions
Q1 2021: 6 institutionsQ2 2021: 6 institutionsQ3 2021: 7 institutionsQ4 2021: 22 institutionsQ1 2022: 26 institutionsQ2 2022: 25 institutionsQ3 2022: 29 institutionsQ4 2022: 27 institutionsQ1 2023: 29 institutionsQ2 2023: 29 institutionsQ3 2023: 28 institutionsQ4 2023: 34 institutionsQ1 2024: 64 institutionsQ2 2024: 71 institutionsQ3 2024: 69 institutionsQ4 2024: 65 institutionsQ1 2025: 59 institutionsQ2 2025: 55 institutionsQ3 2025: 54 institutionsQ4 2025: 58 institutionsQ1 2026: 56 institutionsQ2 2026: 72 institutions
Value heldQ3 2024: $493.1M
Q1 2021: $55.9MQ2 2021: $56.4MQ3 2021: $39.4MQ4 2021: $246.6MQ1 2022: $218.3MQ2 2022: $116.4MQ3 2022: $183.4MQ4 2022: $275.7MQ1 2023: $110.2MQ2 2023: $101.8MQ3 2023: $187.6MQ4 2023: $343.9MQ1 2024: $588.0MQ2 2024: $502.1MQ3 2024: $493.1MQ4 2024: $168.2MQ1 2025: $60.6MQ2 2025: $108.0MQ3 2025: $96.4MQ4 2025: $106.1MQ1 2026: $102.1MQ2 2026: $236.2M
Institutions holding SLN and their total value by quarter
QuarterHoldersValue
Q2 202672$236.2M
Q1 202656$102.1M
Q4 202558$106.1M
Q3 202554$96.4M
Q2 202555$108.0M
Q1 202559$60.6M
Q4 202465$168.2M
Q3 202469$493.1M
Q2 202471$502.1M
Q1 202464$588.0M
Q4 202334$343.9M
Q3 202328$187.6M
Q2 202329$101.8M
Q1 202329$110.2M
Q4 202227$275.7M
Q3 202229$183.4M
Q2 202225$116.4M
Q1 202226$218.3M
Q4 202122$246.6M
Q3 20217$39.4M
Q2 20216$56.4M
Q1 20216$55.9M

Institutions, Q3 2024

Shares, value and share of portfolio for each institution holding Silence Therapeutics plc; share changes are against Q2 2024.

Institutions holding SLN in Q3 2024
InstitutionSharesValue% of portfolioChange in sharesAction
TCG Crossover Management, LLC3,033,560$55.2M4.67%−261,790−7.9%Reduced
Siren, L.L.C.2,831,770$51.5M2.58%+2,831,770New
Lombard Odier Asset Management (USA) Corp2,664,077$36.2M13.46%+258,079+10.7%Added
Redmile Group, LLC1,899,317$34.5M2.03%−114,979−5.7%Reduced
Frazier Life Sciences Management, L.P.1,148,591$20.9M0.84%00.0%Unchanged
Millennium Management LLC1,110,230$20.2M0.02%+327,289+41.8%Added
Vivo Capital, LLC1,105,454$20.1M1.66%00.0%Unchanged
Janus Henderson Group PLC1,087,228$19.8M0.01%+268,250+32.8%Added
Deep Track Capital, LP1,000,000$18.2M0.58%−359,745−26.5%Reduced
Polar Capital Holdings Plc1,000,000$18.2M0.11%+59,836+6.4%Added
Nextech Invest AG952,400$17.3M2.43%00.0%Unchanged
Morgan Stanley721,417$13.1M0.00%+417,424+137.3%Added
Eventide Asset Management, LLC640,000$11.6M0.20%+640,000New
Parkman Healthcare Partners LLC497,870$9.05M1.16%+208,029+71.8%Added
Saturn V Capital Management LLC481,127$8.75M3.13%+481,127New
5AM Venture Management, LLC476,200$8.66M1.79%00.0%Unchanged
Point72 Asset Management, L.P.467,800$8.50M0.03%+321,300+219.3%Added
Citadel Advisors LLC436,697$7.94M0.01%+319,937+274.0%Added
Woodline Partners LP406,903$7.40M0.06%+316,041+347.8%Added
Cormorant Asset Management, LP400,000$7.27M0.39%−225,000−36.0%Reduced
Duquesne Family Office LLCSuperinvestorDuquesne Family Office387,400$7.04M0.25%00.0%Unchanged
Mangrove Partners385,408$7.01M0.68%00.0%Unchanged
SG Americas Securities, LLC343,190$6.24M0.02%−60.0%Reduced
ExodusPoint Capital Management, LP338,681$6.16M0.06%+338,681New
Cantor Fitzgerald, L. P.334,192$6.08M0.55%+86,226+34.8%Added
Adage Capital Partners GP, L.L.C.320,000$5.82M0.01%−280,000−46.7%Reduced
Aquilo Capital Management, LLC317,214$5.77M6.49%−183,000−36.6%Reduced
Soleus Capital Management, L.P.260,000$4.73M0.39%+260,000New
Price T Rowe Associates Inc228,644$4.16M0.00%+228,644New
Logos Global Management LP200,000$3.64M0.41%−1,276,061−86.5%Reduced
Nantahala Capital Management, LLC200,000$3.64M0.31%00.0%Unchanged
Ikarian Capital, LLC587,343$3.37M1.05%+80,678+15.9%Added
M28 Capital Management LP185,100$3.37M3.70%00.0%Unchanged
HSBC Holdings PLC177,834$3.23M0.00%00.0%Unchanged
Boothbay Fund Management, LLC171,155$3.11M0.10%+24,303+16.5%Added
Two Sigma Investments, LP169,392$3.08M0.01%+70,285+70.9%Added
Marshall Wace, LLP168,417$3.06M0.00%+19,020+12.7%Added
Schonfeld Strategic Advisors LLC166,000$3.02M0.02%+90,963+121.2%Added
BIT Capital GmbH92,429$1.68M0.16%−8,806−8.7%Reduced
UBS Oconnor LLC85,701$1.56M0.04%+8,861+11.5%Added
Two Sigma Advisers, LP83,300$1.51M0.00%+7,100+9.3%Added
UBS Group AG70,661$1.28M0.00%−3,145−4.3%Reduced
Bank of Montreal65,259$1.19M0.00%+65,259New
Citigroup Inc58,333$1.06M0.00%00.0%Unchanged
Artia Global Partners LP52,476$954.0K0.27%00.0%Unchanged
NEOS Investment Management LLC51,712$940.1K0.03%+14,548+39.1%Added
Cubist Systematic Strategies, LLC46,305$841.8K0.01%+36,867+390.6%Added
ADAR1 Capital Management, LLC40,290$732.5K0.12%00.0%Unchanged
TD Asset Management Inc30,600$558.5K0.00%+30,600New
Goldman Sachs Group Inc30,632$556.9K0.00%+14,376+88.4%Added
Geode Capital Management, LLC29,417$534.8K0.00%00.0%Unchanged
Y-Intercept (Hong Kong) Ltd21,078$383.2K0.02%+3,923+22.9%Added
Blair William & Co20,000$363.6K0.00%−5,432−21.4%Reduced
Qube Research & Technologies Ltd19,196$349.0K0.00%+19,196New
Rathbone Brothers plc18,421$334.9K0.00%00.0%Unchanged
Manufacturers Life Insurance Company, The17,490$318.0K0.00%+17,490New
Custom Index Systems, LLC14,415$262.1K0.14%−421−2.8%Reduced
Advisor Group Holdings, Inc.13,159$239.1K0.00%+318+2.5%Added
Verition Fund Management LLC11,390$207.1K0.00%+11,390New
Vestcor Inc8,800$160.0K0.01%00.0%Unchanged
Virtus ETF Advisers LLC4,674$85.0K0.04%+83+1.8%Added
Barclays PLC3,333$60.6K0.00%−2,237−40.2%Reduced
Values First Advisors, Inc.3,091$56.2K0.03%+3,091New
Royal Bank of Canada1,941$35.0K0.00%−2,775−58.8%Reduced
Bank of America Corp1,034$18.8K0.00%−8,978−89.7%Reduced
GAMMA Investing LLC859$15.6K0.00%00.0%Unchanged
Rhumbline Advisers754$13.7K0.00%+285+60.8%Added
Steward Partners Investment Advisory, LLC100$1.82K0.00%00.0%Unchanged
Wells Fargo & Company19$3450.00%+19New
Artal Group S.A.0$00.00%−2,779,619−100.0%Sold out
First Turn Management, LLC0$00.00%−537,338−100.0%Sold out
Hudson Bay Capital Management LP0$00.00%−208,064−100.0%Sold out
Octagon Capital Advisors LP0$00.00%−176,000−100.0%Sold out
Nicholas Investment Partners, LP0$00.00%−150,480−100.0%Sold out
StemPoint Capital LP0$00.00%−124,866−100.0%Sold out
Walleye Capital LLC0$00.00%−74,220−100.0%Sold out
Renaissance Technologies LLC0$00.00%−39,100−100.0%Sold out
New York State Common Retirement Fund0$00.00%−24,066−100.0%Sold out
Trexquant Investment LP0$00.00%−21,803−100.0%Sold out
Legato Capital Management LLC0$00.00%−19,800−100.0%Sold out
Jump Financial, LLC0$00.00%−12,342−100.0%Sold out
Quarry LP0$00.00%−6,000−100.0%Sold out
Advisors Preferred, LLC0$00.00%−5,315−100.0%Sold out
Lazard Asset Management LLC0$00.00%−60−100.0%Sold out