Silence Therapeutics plc
SLN- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001479615
No open-market purchases or sales by Silence Therapeutics plc insiders were filed in the last 90 days; 72 institutions reported holding it in 13F filings for Q2 2026, worth $236.2M in total; no superinvestor holds it.
Other share classesSLNCF
13F holders, Q3 2025
Institutional positions in Silence Therapeutics plc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 54
- −1 vs. Q2 2025
- Shares held
- 19.7M
- −55.2K (−0.3%) vs. Q2 2025
- Total value
- $96.4M
- −$11.6M (−10.7%) vs. Q2 2025
- New holders
- 6
- 15 more added
- Sold out
- 7
- 16 more reduced
Compare with Q2 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting SLN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 72 | $236.2M |
| Q1 2026 | 56 | $102.1M |
| Q4 2025 | 58 | $106.1M |
| Q3 2025 | 54 | $96.4M |
| Q2 2025 | 55 | $108.0M |
| Q1 2025 | 59 | $60.6M |
| Q4 2024 | 65 | $168.2M |
| Q3 2024 | 69 | $493.1M |
| Q2 2024 | 71 | $502.1M |
| Q1 2024 | 64 | $588.0M |
| Q4 2023 | 34 | $343.9M |
| Q3 2023 | 28 | $187.6M |
| Q2 2023 | 29 | $101.8M |
| Q1 2023 | 29 | $110.2M |
| Q4 2022 | 27 | $275.7M |
| Q3 2022 | 29 | $183.4M |
| Q2 2022 | 25 | $116.4M |
| Q1 2022 | 26 | $218.3M |
| Q4 2021 | 22 | $246.6M |
| Q3 2021 | 7 | $39.4M |
| Q2 2021 | 6 | $56.4M |
| Q1 2021 | 6 | $55.9M |
Institutions, Q3 2025
Shares, value and share of portfolio for each institution holding Silence Therapeutics plc; share changes are against Q2 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| TCG Crossover Management, LLC | 3,033,560 | $15.7M | 0.77% | 00.0% | Unchanged |
| Siren, L.L.C. | 2,911,438 | $15.1M | 0.59% | 00.0% | Unchanged |
| Redmile Group, LLC | 2,164,777 | $11.2M | 1.09% | 00.0% | Unchanged |
| Lombard Odier Asset Management (USA) Corp | 1,844,948 | $7.12M | 1.61% | −4,786−0.3% | Reduced |
| Morgan Stanley | 1,207,724 | $6.27M | 0.00% | −4,034−0.3% | Reduced |
| Vivo Capital, LLC | 1,105,454 | $5.74M | 0.46% | 00.0% | Unchanged |
| Nantahala Capital Management, LLC | 1,042,427 | $5.41M | 0.33% | 00.0% | Unchanged |
| Frazier Life Sciences Management, L.P. | 970,130 | $5.03M | 0.15% | 00.0% | Unchanged |
| Nextech Invest, Ltd. | 952,400 | $4.94M | 0.75% | 00.0% | Unchanged |
| Cantor Fitzgerald, L. P. | 801,306 | $4.16M | 0.08% | +12,267+1.6% | Added |
| 5AM Venture Management, LLC | 476,200 | $2.47M | 0.91% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 308,289 | $1.60M | 0.01% | −420.0% | Reduced |
| UBS Group AG | 307,363 | $1.60M | 0.00% | +78,854+34.5% | Added |
| Millennium Management LLC | 298,512 | $1.55M | 0.00% | +99,865+50.3% | Added |
| Boothbay Fund Management, LLC | 279,637 | $1.45M | 0.04% | +27,216+10.8% | Added |
| Ikarian Capital, LLC | 900,784 | $1.31M | 0.30% | +27,216+3.1% | Added |
| M28 Capital Management LP | 185,100 | $960.7K | 1.41% | 00.0% | Unchanged |
| HSBC Holdings PLC | 172,873 | $909.3K | 0.00% | +390.0% | Added |
| Bank of Montreal | 153,782 | $798.1K | 0.00% | +7,970+5.5% | Added |
| Marshall Wace, LLP | 83,219 | $431.9K | 0.00% | −92,643−52.7% | Reduced |
| Two Sigma Investments, LP | 63,247 | $328.3K | 0.00% | +3,935+6.6% | Added |
| Woodline Partners LP | 62,459 | $324.2K | 0.00% | 00.0% | Unchanged |
| BlackRock, Inc. | 61,832 | $320.9K | 0.00% | −106,403−63.2% | Reduced |
| Advisor Group Holdings, Inc. | 62,171 | $298.9K | 0.00% | −7,210−10.4% | Reduced |
| Two Sigma Advisers, LP | 42,600 | $221.1K | 0.00% | +3,000+7.6% | Added |
| Geode Capital Management, LLC | 29,538 | $153.3K | 0.00% | 00.0% | Unchanged |
| Goldman Sachs Group Inc | 22,644 | $117.5K | 0.00% | +22,644 | New |
| Citadel Advisors LLC | 21,505 | $111.6K | 0.00% | +21,505 | New |
| Virtus Investment Advisers, Inc. | 20,374 | $105.7K | 0.03% | +3,537+21.0% | Added |
| ADAR1 Capital Management, LLC | 18,643 | $96.8K | 0.01% | 00.0% | Unchanged |
| HRT Financial LP | 10,887 | $56.0K | 0.00% | +10,887 | New |
| EHP Funds Inc. | 10,673 | $55.4K | 0.07% | +10,673 | New |
| Cambridge Investment Research Advisors, Inc. | 10,194 | $53.0K | 0.00% | 00.0% | Unchanged |
| GAMMA Investing LLC | 9,915 | $51.5K | 0.00% | +1,582+19.0% | Added |
| China Universal Asset Management Co., Ltd. | 8,232 | $42.7K | 0.00% | −1,214−12.9% | Reduced |
| JPMorgan Chase & Co | 7,766 | $40.3K | 0.00% | +483+6.6% | Added |
| Wexford Capital LP | 7,708 | $40.0K | 0.01% | −19,441−71.6% | Reduced |
| Barclays PLC | 7,136 | $37.0K | 0.00% | +101+1.4% | Added |
| Rhumbline Advisers | 5,865 | $30.4K | 0.00% | −331−5.3% | Reduced |
| Acadian Asset Management LLC | 4,218 | $21.0K | 0.00% | +4,218 | New |
| Bank of America Corp | 3,531 | $18.3K | 0.00% | −1,564−30.7% | Reduced |
| Jones Financial Companies LLLP | 2,500 | $13.8K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 2,447 | $12.7K | 0.00% | +19+0.8% | Added |
| Mirae Asset Global Investments Co., Ltd. | 1,816 | $9.43K | 0.00% | −1−0.1% | Reduced |
| Citigroup Inc | 1,773 | $9.20K | 0.00% | −1,701−49.0% | Reduced |
| Parallel Advisors, LLC | 1,300 | $6.75K | 0.00% | 00.0% | Unchanged |
| Royal Bank of Canada | 1,136 | $6.00K | 0.00% | −1,326−53.9% | Reduced |
| GF Fund Management Co. Ltd. | 978 | $5.08K | 0.00% | −187−16.1% | Reduced |
| BNP Paribas Arbitrage, SA | 600 | $3.11K | 0.00% | −100−14.3% | Reduced |
| Simplex Trading, LLC | 651 | $3.00K | 0.00% | −16−2.4% | Reduced |
| Steward Partners Investment Advisory, LLC | 100 | $519 | 0.00% | 00.0% | Unchanged |
| Rockefeller Capital Management L.P. | 45 | $234 | 0.00% | +45 | New |
| SBI Securities Co., Ltd. | 29 | $151 | 0.00% | +1+3.6% | Added |
| Principal Securities, Inc. | 17 | $88 | 0.00% | 00.0% | Unchanged |
| Jane Street Group, LLC | 0 | $0 | 0.00% | −37,813−100.0% | Sold out |
| Saturn V Capital Management LLC | 0 | $0 | 0.00% | −34,737−100.0% | Sold out |
| Susquehanna International Group, LLP | 0 | $0 | 0.00% | −27,797−100.0% | Sold out |
| Massar Capital Management, LP | 0 | $0 | 0.00% | −19,863−100.0% | Sold out |
| Rathbone Brothers plc | 0 | $0 | 0.00% | −18,421−100.0% | Sold out |
| Beacon Pointe Advisors, LLC | 0 | $0 | 0.00% | −11,615−100.0% | Sold out |
| EverSource Wealth Advisors, LLC | 0 | $0 | 0.00% | −10−100.0% | Sold out |