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Silence Therapeutics plc

SLN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001479615

No open-market purchases or sales by Silence Therapeutics plc insiders were filed in the last 90 days; 72 institutions reported holding it in 13F filings for Q2 2026, worth $236.2M in total; no superinvestor holds it.

Other share classesSLNCF

13F holders, Q3 2025

Institutional positions in Silence Therapeutics plc as of Sep 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
54
−1 vs. Q2 2025
Shares held
19.7M
−55.2K (−0.3%) vs. Q2 2025
Total value
$96.4M
−$11.6M (−10.7%) vs. Q2 2025
New holders
6
15 more added
Sold out
7
16 more reduced

Compare with Q2 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SLN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ3 2025: 54 institutions
Q1 2021: 6 institutionsQ2 2021: 6 institutionsQ3 2021: 7 institutionsQ4 2021: 22 institutionsQ1 2022: 26 institutionsQ2 2022: 25 institutionsQ3 2022: 29 institutionsQ4 2022: 27 institutionsQ1 2023: 29 institutionsQ2 2023: 29 institutionsQ3 2023: 28 institutionsQ4 2023: 34 institutionsQ1 2024: 64 institutionsQ2 2024: 71 institutionsQ3 2024: 69 institutionsQ4 2024: 65 institutionsQ1 2025: 59 institutionsQ2 2025: 55 institutionsQ3 2025: 54 institutionsQ4 2025: 58 institutionsQ1 2026: 56 institutionsQ2 2026: 72 institutions
Value heldQ3 2025: $96.4M
Q1 2021: $55.9MQ2 2021: $56.4MQ3 2021: $39.4MQ4 2021: $246.6MQ1 2022: $218.3MQ2 2022: $116.4MQ3 2022: $183.4MQ4 2022: $275.7MQ1 2023: $110.2MQ2 2023: $101.8MQ3 2023: $187.6MQ4 2023: $343.9MQ1 2024: $588.0MQ2 2024: $502.1MQ3 2024: $493.1MQ4 2024: $168.2MQ1 2025: $60.6MQ2 2025: $108.0MQ3 2025: $96.4MQ4 2025: $106.1MQ1 2026: $102.1MQ2 2026: $236.2M
Institutions holding SLN and their total value by quarter
QuarterHoldersValue
Q2 202672$236.2M
Q1 202656$102.1M
Q4 202558$106.1M
Q3 202554$96.4M
Q2 202555$108.0M
Q1 202559$60.6M
Q4 202465$168.2M
Q3 202469$493.1M
Q2 202471$502.1M
Q1 202464$588.0M
Q4 202334$343.9M
Q3 202328$187.6M
Q2 202329$101.8M
Q1 202329$110.2M
Q4 202227$275.7M
Q3 202229$183.4M
Q2 202225$116.4M
Q1 202226$218.3M
Q4 202122$246.6M
Q3 20217$39.4M
Q2 20216$56.4M
Q1 20216$55.9M

Institutions, Q3 2025

Shares, value and share of portfolio for each institution holding Silence Therapeutics plc; share changes are against Q2 2025.

Institutions holding SLN in Q3 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Principal Securities, Inc.17$880.00%00.0%Unchanged
SBI Securities Co., Ltd.29$1510.00%+1+3.6%Added
Rockefeller Capital Management L.P.45$2340.00%+45New
Steward Partners Investment Advisory, LLC100$5190.00%00.0%Unchanged
Simplex Trading, LLC651$3.00K0.00%−16−2.4%Reduced
BNP Paribas Arbitrage, SA600$3.11K0.00%−100−14.3%Reduced
GF Fund Management Co. Ltd.978$5.08K0.00%−187−16.1%Reduced
Royal Bank of Canada1,136$6.00K0.00%−1,326−53.9%Reduced
Parallel Advisors, LLC1,300$6.75K0.00%00.0%Unchanged
Citigroup Inc1,773$9.20K0.00%−1,701−49.0%Reduced
Mirae Asset Global Investments Co., Ltd.1,816$9.43K0.00%−1−0.1%Reduced
Tower Research Capital LLC (TRC)2,447$12.7K0.00%+19+0.8%Added
Jones Financial Companies LLLP2,500$13.8K0.00%00.0%Unchanged
Bank of America Corp3,531$18.3K0.00%−1,564−30.7%Reduced
Acadian Asset Management LLC4,218$21.0K0.00%+4,218New
Rhumbline Advisers5,865$30.4K0.00%−331−5.3%Reduced
Barclays PLC7,136$37.0K0.00%+101+1.4%Added
Wexford Capital LP7,708$40.0K0.01%−19,441−71.6%Reduced
JPMorgan Chase & Co7,766$40.3K0.00%+483+6.6%Added
China Universal Asset Management Co., Ltd.8,232$42.7K0.00%−1,214−12.9%Reduced
GAMMA Investing LLC9,915$51.5K0.00%+1,582+19.0%Added
Cambridge Investment Research Advisors, Inc.10,194$53.0K0.00%00.0%Unchanged
EHP Funds Inc.10,673$55.4K0.07%+10,673New
HRT Financial LP10,887$56.0K0.00%+10,887New
ADAR1 Capital Management, LLC18,643$96.8K0.01%00.0%Unchanged
Virtus Investment Advisers, Inc.20,374$105.7K0.03%+3,537+21.0%Added
Citadel Advisors LLC21,505$111.6K0.00%+21,505New
Goldman Sachs Group Inc22,644$117.5K0.00%+22,644New
Geode Capital Management, LLC29,538$153.3K0.00%00.0%Unchanged
Two Sigma Advisers, LP42,600$221.1K0.00%+3,000+7.6%Added
Advisor Group Holdings, Inc.62,171$298.9K0.00%−7,210−10.4%Reduced
BlackRock, Inc.61,832$320.9K0.00%−106,403−63.2%Reduced
Woodline Partners LP62,459$324.2K0.00%00.0%Unchanged
Two Sigma Investments, LP63,247$328.3K0.00%+3,935+6.6%Added
Marshall Wace, LLP83,219$431.9K0.00%−92,643−52.7%Reduced
Bank of Montreal153,782$798.1K0.00%+7,970+5.5%Added
HSBC Holdings PLC172,873$909.3K0.00%+390.0%Added
M28 Capital Management LP185,100$960.7K1.41%00.0%Unchanged
Ikarian Capital, LLC900,784$1.31M0.30%+27,216+3.1%Added
Boothbay Fund Management, LLC279,637$1.45M0.04%+27,216+10.8%Added
Millennium Management LLC298,512$1.55M0.00%+99,865+50.3%Added
UBS Group AG307,363$1.60M0.00%+78,854+34.5%Added
SG Americas Securities, LLC308,289$1.60M0.01%−420.0%Reduced
5AM Venture Management, LLC476,200$2.47M0.91%00.0%Unchanged
Cantor Fitzgerald, L. P.801,306$4.16M0.08%+12,267+1.6%Added
Nextech Invest, Ltd.952,400$4.94M0.75%00.0%Unchanged
Frazier Life Sciences Management, L.P.970,130$5.03M0.15%00.0%Unchanged
Nantahala Capital Management, LLC1,042,427$5.41M0.33%00.0%Unchanged
Vivo Capital, LLC1,105,454$5.74M0.46%00.0%Unchanged
Morgan Stanley1,207,724$6.27M0.00%−4,034−0.3%Reduced
Lombard Odier Asset Management (USA) Corp1,844,948$7.12M1.61%−4,786−0.3%Reduced
Redmile Group, LLC2,164,777$11.2M1.09%00.0%Unchanged
Siren, L.L.C.2,911,438$15.1M0.59%00.0%Unchanged
TCG Crossover Management, LLC3,033,560$15.7M0.77%00.0%Unchanged
Jane Street Group, LLC0$00.00%−37,813−100.0%Sold out
Saturn V Capital Management LLC0$00.00%−34,737−100.0%Sold out
Susquehanna International Group, LLP0$00.00%−27,797−100.0%Sold out
Massar Capital Management, LP0$00.00%−19,863−100.0%Sold out
Rathbone Brothers plc0$00.00%−18,421−100.0%Sold out
Beacon Pointe Advisors, LLC0$00.00%−11,615−100.0%Sold out
EverSource Wealth Advisors, LLC0$00.00%−10−100.0%Sold out