Silence Therapeutics plc
SLN- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001479615
No open-market purchases or sales by Silence Therapeutics plc insiders were filed in the last 90 days; 72 institutions reported holding it in 13F filings for Q2 2026, worth $236.2M in total; no superinvestor holds it.
Other share classesSLNCF
13F holders, Q1 2025
Institutional positions in Silence Therapeutics plc as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 59
- −5 vs. Q4 2024
- Shares held
- 21.9M
- −1.95M (−8.2%) vs. Q4 2024
- Total value
- $60.6M
- −$101.0M (−62.5%) vs. Q4 2024
- New holders
- 6
- 18 more added
- Sold out
- 11
- 25 more reduced
1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.
Compare with Q4 2024: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting SLN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 72 | $236.2M |
| Q1 2026 | 56 | $102.1M |
| Q4 2025 | 58 | $106.1M |
| Q3 2025 | 54 | $96.4M |
| Q2 2025 | 55 | $108.0M |
| Q1 2025 | 59 | $60.6M |
| Q4 2024 | 65 | $168.2M |
| Q3 2024 | 69 | $493.1M |
| Q2 2024 | 71 | $502.1M |
| Q1 2024 | 64 | $588.0M |
| Q4 2023 | 34 | $343.9M |
| Q3 2023 | 28 | $187.6M |
| Q2 2023 | 29 | $101.8M |
| Q1 2023 | 29 | $110.2M |
| Q4 2022 | 27 | $275.7M |
| Q3 2022 | 29 | $183.4M |
| Q2 2022 | 25 | $116.4M |
| Q1 2022 | 26 | $218.3M |
| Q4 2021 | 22 | $246.6M |
| Q3 2021 | 7 | $39.4M |
| Q2 2021 | 6 | $56.4M |
| Q1 2021 | 6 | $55.9M |
Institutions, Q1 2025
Shares, value and share of portfolio for each institution holding Silence Therapeutics plc; share changes are against Q4 2024.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| TCG Crossover Management, LLC | 3,033,560 | $8.55M | 1.17% | 00.0% | Unchanged |
| Siren, L.L.C. | 2,789,833 | $7.87M | 0.44% | −41,937−1.5% | Reduced |
| Redmile Group, LLC | 2,214,947 | $6.25M | 0.59% | −184,370−7.7% | Reduced |
| Morgan Stanley | 2,000,105 | $5.64M | 0.00% | +337,037+20.3% | Added |
| Lombard Odier Asset Management (USA) Corp | 1,849,734 | $4.04M | 1.36% | −6,289−0.3% | Reduced |
| Frazier Life Sciences Management, L.P. | 1,148,591 | $3.24M | 0.15% | 00.0% | Unchanged |
| Vivo Capital, LLC | 1,105,454 | $3.12M | 0.41% | 00.0% | Unchanged |
| Nantahala Capital Management, LLC | 1,042,427 | $2.94M | 0.24% | −7,249−0.7% | Reduced |
| Nextech Invest, Ltd. | 952,400 | $2.69M | 0.62% | +952,400 | New |
| Cantor Fitzgerald, L. P. | 773,845 | $2.18M | 0.08% | +234,119+43.4% | Added |
| Saturn V Capital Management LLC | 732,463 | $2.07M | 1.04% | +337,439+85.4% | Added |
| 5AM Venture Management, LLC | 476,200 | $1.34M | 0.51% | 00.0% | Unchanged |
| Parkman Healthcare Partners LLC | 401,746 | $1.13M | 0.13% | −89,334−18.2% | Reduced |
| Millennium Management LLC | 396,862 | $1.12M | 0.00% | −76,690−16.2% | Reduced |
| UBS Group AG | 319,514 | $901.0K | 0.00% | −36,557−10.3% | Reduced |
| SG Americas Securities, LLC | 308,289 | $869.0K | 0.00% | −9,339−2.9% | Reduced |
| Boothbay Fund Management, LLC | 250,012 | $705.0K | 0.03% | −101,515−28.9% | Reduced |
| Marshall Wace, LLP | 228,418 | $644.1K | 0.00% | −260,471−53.3% | Reduced |
| M28 Capital Management LP | 185,100 | $522.0K | 0.72% | 00.0% | Unchanged |
| BlackRock, Inc. | 180,435 | $508.8K | 0.00% | −31,072−14.7% | Reduced |
| HSBC Holdings PLC | 172,834 | $499.5K | 0.00% | 00.0% | Unchanged |
| Bank of Montreal | 158,593 | $447.2K | 0.00% | +93,586+144.0% | Added |
| Schonfeld Strategic Advisors LLC | 149,996 | $423.0K | 0.00% | +26,796+21.8% | Added |
| Walleye Capital LLC | 136,150 | $383.9K | 0.00% | +99,753+274.1% | Added |
| Woodline Partners LP | 134,492 | $379.3K | 0.00% | −364,240−73.0% | Reduced |
| Two Sigma Investments, LP | 76,008 | $214.3K | 0.00% | −66,044−46.5% | Reduced |
| Advisor Group Holdings, Inc. | 71,497 | $201.5K | 0.00% | +30,630+75.0% | Added |
| Bank of America Corp | 64,886 | $183.0K | 0.00% | −434,180−87.0% | Reduced |
| UBS Oconnor LLC | 62,639 | $176.6K | 0.00% | −66,351−51.4% | Reduced |
| Citadel Advisors LLC | 62,441 | $176.1K | 0.00% | −220,296−77.9% | Reduced |
| Citigroup Inc | 61,071 | $172.2K | 0.00% | +569+0.9% | Added |
| Two Sigma Advisers, LP | 49,200 | $138.7K | 0.00% | −49,600−50.2% | Reduced |
| Shay Capital LLC | 47,728 | $134.6K | 0.04% | +47,728 | New |
| JPMorgan Chase & Co | 35,414 | $99.9K | 0.00% | +31,621+833.7% | Added |
| Geode Capital Management, LLC | 29,417 | $83.0K | 0.00% | 00.0% | Unchanged |
| Jump Financial, LLC | 26,351 | $74.3K | 0.00% | +26,351 | New |
| Virtus Investment Advisers, Inc. | 24,872 | $70.1K | 0.02% | +24,872 | New |
| Goldman Sachs Group Inc | 24,375 | $68.7K | 0.00% | −12,510−33.9% | Reduced |
| Qube Research & Technologies Ltd | 18,913 | $53.3K | 0.00% | −35,833−65.5% | Reduced |
| ADAR1 Capital Management, LLC | 18,643 | $52.6K | 0.01% | +643+3.6% | Added |
| Rathbone Brothers plc | 18,421 | $51.9K | 0.00% | 00.0% | Unchanged |
| Point72 Asset Management, L.P. | 16,032 | $45.2K | 0.00% | −617,068−97.5% | Reduced |
| Acadian Asset Management LLC | 12,153 | $34.0K | 0.00% | −7,314−37.6% | Reduced |
| China Universal Asset Management Co., Ltd. | 9,432 | $26.6K | 0.00% | −531−5.3% | Reduced |
| Cubist Systematic Strategies, LLC | 7,364 | $20.8K | 0.00% | −98,956−93.1% | Reduced |
| Barclays PLC | 6,854 | $19.3K | 0.00% | +728+11.9% | Added |
| FNY Investment Advisers, LLC | 7,000 | $19.0K | 0.01% | −10,515−60.0% | Reduced |
| BNP Paribas Arbitrage, SA | 4,788 | $13.5K | 0.00% | +3,004+168.4% | Added |
| Royal Bank of Canada | 4,263 | $12.0K | 0.00% | +2,748+181.4% | Added |
| GAMMA Investing LLC | 3,560 | $10.0K | 0.00% | −2,532−41.6% | Reduced |
| Jones Financial Companies LLLP | 2,500 | $8.60K | 0.00% | +2,500 | New |
| Tower Research Capital LLC (TRC) | 2,367 | $6.67K | 0.00% | +1,735+274.5% | Added |
| Mirae Asset Global Investments Co., Ltd. | 1,573 | $5.41K | 0.00% | +7+0.4% | Added |
| Rhumbline Advisers | 1,875 | $5.28K | 0.00% | +1,034+122.9% | Added |
| Parallel Advisors, LLC | 1,300 | $3.67K | 0.00% | +1,300 | New |
| GF Fund Management Co. Ltd. | 1,165 | $3.29K | 0.00% | +178+18.0% | Added |
| Steward Partners Investment Advisory, LLC | 100 | $282 | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 28 | $79 | 0.00% | 00.0% | Unchanged |
| Simplex Trading, LLC | 251 | $0 | 0.00% | +200+392.2% | Added |
| Eventide Asset Management, LLC | 0 | $0 | 0.00% | −640,000−100.0% | Sold out |
| Aquilo Capital Management, LLC | 0 | $0 | 0.00% | −367,214−100.0% | Sold out |
| Integral Health Asset Management, LLC | 0 | $0 | 0.00% | −200,000−100.0% | Sold out |
| Trexquant Investment LP | 0 | $0 | 0.00% | −63,663−100.0% | Sold out |
| Verition Fund Management LLC | 0 | $0 | 0.00% | −24,123−100.0% | Sold out |
| Y-Intercept (Hong Kong) Ltd | 0 | $0 | 0.00% | −21,217−100.0% | Sold out |
| Commonwealth of Pennsylvania Public School Empls Retrmt Sys | 0 | $0 | 0.00% | −19,467−100.0% | Sold out |
| Ameriprise Financial Inc | 0 | $0 | 0.00% | −16,360−100.0% | Sold out |
| Custom Index Systems, LLC | 0 | $0 | 0.00% | −11,861−100.0% | Sold out |
| Virtus ETF Advisers LLC | 0 | $0 | 0.00% | −10,772−100.0% | Sold out |
| Wells Fargo & Company | 0 | $0 | 0.00% | −19−100.0% | Sold out |
| Nextech Invest AG | – | – | – | – | Not filed |