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Silence Therapeutics plc

SLN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001479615

No open-market purchases or sales by Silence Therapeutics plc insiders were filed in the last 90 days; 72 institutions reported holding it in 13F filings for Q2 2026, worth $236.2M in total; no superinvestor holds it.

Other share classesSLNCF

13F holders, Q1 2025

Institutional positions in Silence Therapeutics plc as of Mar 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
59
−5 vs. Q4 2024
Shares held
21.9M
−1.95M (−8.2%) vs. Q4 2024
Total value
$60.6M
−$101.0M (−62.5%) vs. Q4 2024
New holders
6
18 more added
Sold out
11
25 more reduced

1 institution that held it in Q4 2024 haven't filed for Q1 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SLN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2025: 59 institutions
Q1 2021: 6 institutionsQ2 2021: 6 institutionsQ3 2021: 7 institutionsQ4 2021: 22 institutionsQ1 2022: 26 institutionsQ2 2022: 25 institutionsQ3 2022: 29 institutionsQ4 2022: 27 institutionsQ1 2023: 29 institutionsQ2 2023: 29 institutionsQ3 2023: 28 institutionsQ4 2023: 34 institutionsQ1 2024: 64 institutionsQ2 2024: 71 institutionsQ3 2024: 69 institutionsQ4 2024: 65 institutionsQ1 2025: 59 institutionsQ2 2025: 55 institutionsQ3 2025: 54 institutionsQ4 2025: 58 institutionsQ1 2026: 56 institutionsQ2 2026: 72 institutions
Value heldQ1 2025: $60.6M
Q1 2021: $55.9MQ2 2021: $56.4MQ3 2021: $39.4MQ4 2021: $246.6MQ1 2022: $218.3MQ2 2022: $116.4MQ3 2022: $183.4MQ4 2022: $275.7MQ1 2023: $110.2MQ2 2023: $101.8MQ3 2023: $187.6MQ4 2023: $343.9MQ1 2024: $588.0MQ2 2024: $502.1MQ3 2024: $493.1MQ4 2024: $168.2MQ1 2025: $60.6MQ2 2025: $108.0MQ3 2025: $96.4MQ4 2025: $106.1MQ1 2026: $102.1MQ2 2026: $236.2M
Institutions holding SLN and their total value by quarter
QuarterHoldersValue
Q2 202672$236.2M
Q1 202656$102.1M
Q4 202558$106.1M
Q3 202554$96.4M
Q2 202555$108.0M
Q1 202559$60.6M
Q4 202465$168.2M
Q3 202469$493.1M
Q2 202471$502.1M
Q1 202464$588.0M
Q4 202334$343.9M
Q3 202328$187.6M
Q2 202329$101.8M
Q1 202329$110.2M
Q4 202227$275.7M
Q3 202229$183.4M
Q2 202225$116.4M
Q1 202226$218.3M
Q4 202122$246.6M
Q3 20217$39.4M
Q2 20216$56.4M
Q1 20216$55.9M

Institutions, Q1 2025

Shares, value and share of portfolio for each institution holding Silence Therapeutics plc; share changes are against Q4 2024.

Institutions holding SLN in Q1 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Simplex Trading, LLC251$00.00%+200+392.2%Added
SBI Securities Co., Ltd.28$790.00%00.0%Unchanged
Steward Partners Investment Advisory, LLC100$2820.00%00.0%Unchanged
GF Fund Management Co. Ltd.1,165$3.29K0.00%+178+18.0%Added
Parallel Advisors, LLC1,300$3.67K0.00%+1,300New
Rhumbline Advisers1,875$5.28K0.00%+1,034+122.9%Added
Mirae Asset Global Investments Co., Ltd.1,573$5.41K0.00%+7+0.4%Added
Tower Research Capital LLC (TRC)2,367$6.67K0.00%+1,735+274.5%Added
Jones Financial Companies LLLP2,500$8.60K0.00%+2,500New
GAMMA Investing LLC3,560$10.0K0.00%−2,532−41.6%Reduced
Royal Bank of Canada4,263$12.0K0.00%+2,748+181.4%Added
BNP Paribas Arbitrage, SA4,788$13.5K0.00%+3,004+168.4%Added
FNY Investment Advisers, LLC7,000$19.0K0.01%−10,515−60.0%Reduced
Barclays PLC6,854$19.3K0.00%+728+11.9%Added
Cubist Systematic Strategies, LLC7,364$20.8K0.00%−98,956−93.1%Reduced
China Universal Asset Management Co., Ltd.9,432$26.6K0.00%−531−5.3%Reduced
Acadian Asset Management LLC12,153$34.0K0.00%−7,314−37.6%Reduced
Point72 Asset Management, L.P.16,032$45.2K0.00%−617,068−97.5%Reduced
Rathbone Brothers plc18,421$51.9K0.00%00.0%Unchanged
ADAR1 Capital Management, LLC18,643$52.6K0.01%+643+3.6%Added
Qube Research & Technologies Ltd18,913$53.3K0.00%−35,833−65.5%Reduced
Goldman Sachs Group Inc24,375$68.7K0.00%−12,510−33.9%Reduced
Virtus Investment Advisers, Inc.24,872$70.1K0.02%+24,872New
Jump Financial, LLC26,351$74.3K0.00%+26,351New
Geode Capital Management, LLC29,417$83.0K0.00%00.0%Unchanged
JPMorgan Chase & Co35,414$99.9K0.00%+31,621+833.7%Added
Shay Capital LLC47,728$134.6K0.04%+47,728New
Two Sigma Advisers, LP49,200$138.7K0.00%−49,600−50.2%Reduced
Citigroup Inc61,071$172.2K0.00%+569+0.9%Added
Citadel Advisors LLC62,441$176.1K0.00%−220,296−77.9%Reduced
UBS Oconnor LLC62,639$176.6K0.00%−66,351−51.4%Reduced
Bank of America Corp64,886$183.0K0.00%−434,180−87.0%Reduced
Advisor Group Holdings, Inc.71,497$201.5K0.00%+30,630+75.0%Added
Two Sigma Investments, LP76,008$214.3K0.00%−66,044−46.5%Reduced
Woodline Partners LP134,492$379.3K0.00%−364,240−73.0%Reduced
Walleye Capital LLC136,150$383.9K0.00%+99,753+274.1%Added
Schonfeld Strategic Advisors LLC149,996$423.0K0.00%+26,796+21.8%Added
Bank of Montreal158,593$447.2K0.00%+93,586+144.0%Added
HSBC Holdings PLC172,834$499.5K0.00%00.0%Unchanged
BlackRock, Inc.180,435$508.8K0.00%−31,072−14.7%Reduced
M28 Capital Management LP185,100$522.0K0.72%00.0%Unchanged
Marshall Wace, LLP228,418$644.1K0.00%−260,471−53.3%Reduced
Boothbay Fund Management, LLC250,012$705.0K0.03%−101,515−28.9%Reduced
SG Americas Securities, LLC308,289$869.0K0.00%−9,339−2.9%Reduced
UBS Group AG319,514$901.0K0.00%−36,557−10.3%Reduced
Millennium Management LLC396,862$1.12M0.00%−76,690−16.2%Reduced
Parkman Healthcare Partners LLC401,746$1.13M0.13%−89,334−18.2%Reduced
5AM Venture Management, LLC476,200$1.34M0.51%00.0%Unchanged
Saturn V Capital Management LLC732,463$2.07M1.04%+337,439+85.4%Added
Cantor Fitzgerald, L. P.773,845$2.18M0.08%+234,119+43.4%Added
Nextech Invest, Ltd.952,400$2.69M0.62%+952,400New
Nantahala Capital Management, LLC1,042,427$2.94M0.24%−7,249−0.7%Reduced
Vivo Capital, LLC1,105,454$3.12M0.41%00.0%Unchanged
Frazier Life Sciences Management, L.P.1,148,591$3.24M0.15%00.0%Unchanged
Lombard Odier Asset Management (USA) Corp1,849,734$4.04M1.36%−6,289−0.3%Reduced
Morgan Stanley2,000,105$5.64M0.00%+337,037+20.3%Added
Redmile Group, LLC2,214,947$6.25M0.59%−184,370−7.7%Reduced
Siren, L.L.C.2,789,833$7.87M0.44%−41,937−1.5%Reduced
TCG Crossover Management, LLC3,033,560$8.55M1.17%00.0%Unchanged
Eventide Asset Management, LLC0$00.00%−640,000−100.0%Sold out
Aquilo Capital Management, LLC0$00.00%−367,214−100.0%Sold out
Integral Health Asset Management, LLC0$00.00%−200,000−100.0%Sold out
Trexquant Investment LP0$00.00%−63,663−100.0%Sold out
Verition Fund Management LLC0$00.00%−24,123−100.0%Sold out
Y-Intercept (Hong Kong) Ltd0$00.00%−21,217−100.0%Sold out
Commonwealth of Pennsylvania Public School Empls Retrmt Sys0$00.00%−19,467−100.0%Sold out
Ameriprise Financial Inc0$00.00%−16,360−100.0%Sold out
Custom Index Systems, LLC0$00.00%−11,861−100.0%Sold out
Virtus ETF Advisers LLC0$00.00%−10,772−100.0%Sold out
Wells Fargo & Company0$00.00%−19−100.0%Sold out
Nextech Invest AG––––Not filed