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Silence Therapeutics plc

SLN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001479615

No open-market purchases or sales by Silence Therapeutics plc insiders were filed in the last 90 days; 72 institutions reported holding it in 13F filings for Q2 2026, worth $236.2M in total; no superinvestor holds it.

Other share classesSLNCF

13F holders, Q1 2024

Institutional positions in Silence Therapeutics plc as of Mar 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
64
+30 vs. Q4 2023
Shares held
27.7M
+7.18M (+35.0%) vs. Q4 2023
Total value
$588.0M
+$244.1M (+71.0%) vs. Q4 2023
New holders
32
17 more added
Sold out
2
11 more reduced

Compare with Q4 2023: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SLN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2024: 64 institutions
Q1 2021: 6 institutionsQ2 2021: 6 institutionsQ3 2021: 7 institutionsQ4 2021: 22 institutionsQ1 2022: 26 institutionsQ2 2022: 25 institutionsQ3 2022: 29 institutionsQ4 2022: 27 institutionsQ1 2023: 29 institutionsQ2 2023: 29 institutionsQ3 2023: 28 institutionsQ4 2023: 34 institutionsQ1 2024: 64 institutionsQ2 2024: 71 institutionsQ3 2024: 69 institutionsQ4 2024: 65 institutionsQ1 2025: 59 institutionsQ2 2025: 55 institutionsQ3 2025: 54 institutionsQ4 2025: 58 institutionsQ1 2026: 56 institutionsQ2 2026: 72 institutions
Value heldQ1 2024: $588.0M
Q1 2021: $55.9MQ2 2021: $56.4MQ3 2021: $39.4MQ4 2021: $246.6MQ1 2022: $218.3MQ2 2022: $116.4MQ3 2022: $183.4MQ4 2022: $275.7MQ1 2023: $110.2MQ2 2023: $101.8MQ3 2023: $187.6MQ4 2023: $343.9MQ1 2024: $588.0MQ2 2024: $502.1MQ3 2024: $493.1MQ4 2024: $168.2MQ1 2025: $60.6MQ2 2025: $108.0MQ3 2025: $96.4MQ4 2025: $106.1MQ1 2026: $102.1MQ2 2026: $236.2M
Institutions holding SLN and their total value by quarter
QuarterHoldersValue
Q2 202672$236.2M
Q1 202656$102.1M
Q4 202558$106.1M
Q3 202554$96.4M
Q2 202555$108.0M
Q1 202559$60.6M
Q4 202465$168.2M
Q3 202469$493.1M
Q2 202471$502.1M
Q1 202464$588.0M
Q4 202334$343.9M
Q3 202328$187.6M
Q2 202329$101.8M
Q1 202329$110.2M
Q4 202227$275.7M
Q3 202229$183.4M
Q2 202225$116.4M
Q1 202226$218.3M
Q4 202122$246.6M
Q3 20217$39.4M
Q2 20216$56.4M
Q1 20216$55.9M

Institutions, Q1 2024

Shares, value and share of portfolio for each institution holding Silence Therapeutics plc; share changes are against Q4 2023.

Institutions holding SLN in Q1 2024
InstitutionSharesValue% of portfolioChange in sharesAction
TCG Crossover Management, LLC3,295,350$71.2M5.63%+1,190,475+56.6%Added
Artal Group S.A.2,779,619$60.0M1.55%−220,381−7.3%Reduced
Lombard Odier Asset Management (Europe) Ltd2,238,039$48.3M3.08%−1,374,838−38.1%Reduced
Redmile Group, LLC2,027,669$43.8M1.61%+2,027,669New
Lombard Odier Asset Management (USA) Corp2,388,912$41.6M5.99%−1,490,261−38.4%Reduced
Deep Track Capital, LP1,643,881$35.5M1.02%−307,699−15.8%Reduced
Logos Global Management LP1,476,061$31.1M3.27%+1,076,061+269.0%Added
Frazier Life Sciences Management, L.P.1,148,591$24.8M1.05%+267,418+30.3%Added
Vivo Capital, LLC1,105,454$23.9M1.88%+595,250+116.7%Added
Nextech Invest AG952,400$20.6M3.26%+952,400New
Janus Henderson Group PLC625,864$13.6M0.01%+625,864New
Cormorant Asset Management, LP625,000$13.5M0.59%+625,000New
Adage Capital Partners GP, L.L.C.600,000$13.0M0.02%+600,000New
Aquilo Capital Management, LLC574,214$12.4M9.30%−469,070−45.0%Reduced
Lynx1 Capital Management LP526,642$11.4M2.93%+290,855+123.4%Added
Polar Capital Holdings Plc500,000$10.8M0.07%+500,000New
5AM Venture Management, LLC476,200$10.3M2.30%+476,200New
Millennium Management LLC409,418$8.84M0.01%+409,418New
Duquesne Family Office LLCSuperinvestorDuquesne Family Office387,400$8.37M0.22%+387,400New
Mangrove Partners385,408$8.32M0.72%+385,408New
Octagon Capital Advisors LP315,000$6.80M0.83%+315,000New
M28 Capital Management LP299,400$6.47M4.78%−64,400−17.7%Reduced
Hudson Bay Capital Management LP276,590$5.97M0.05%+276,590New
Parkman Healthcare Partners LLC244,471$5.28M0.65%+11,529+4.9%Added
Morgan Stanley242,770$5.24M0.00%+179,962+286.5%Added
Woodline Partners LP238,380$5.15M0.05%+189,108+383.8%Added
Nantahala Capital Management, LLC200,000$4.32M0.42%+200,000New
HSBC Holdings PLC177,834$3.84M0.00%00.0%Unchanged
Marshall Wace, LLP139,191$3.01M0.00%+139,191New
Schonfeld Strategic Advisors LLC133,000$2.87M0.02%+83,800+170.3%Added
Boothbay Fund Management, LLC127,224$2.75M0.08%+127,224New
Two Sigma Investments, LP107,212$2.32M0.01%+107,212New
Renaissance Technologies LLC103,900$2.24M0.00%+76,798+283.4%Added
Cantor Fitzgerald, L. P.103,483$2.24M0.53%−43,294−29.5%Reduced
Walleye Capital LLC91,819$1.98M0.02%+91,819New
BIT Capital GmbH89,000$1.92M0.17%+89,000New
Two Sigma Advisers, LP77,400$1.67M0.00%+77,400New
UBS Oconnor LLC72,223$1.56M0.04%−20,975−22.5%Reduced
UBS Group AG71,918$1.55M0.00%+1,972+2.8%Added
Citigroup Inc58,333$1.26M0.00%00.0%Unchanged
Artia Global Partners LP52,476$1.13M0.28%+52,476New
Citadel Advisors LLC42,682$921.9K0.00%+20,945+96.4%Added
ADAR1 Capital Management, LLC40,090$865.9K0.24%+39,900+21,000.0%Added
Cubist Systematic Strategies, LLC36,281$783.7K0.01%+36,281New
Blair William & Co25,432$549.3K0.00%−116−0.5%Reduced
Geode Capital Management, LLC22,427$484.4K0.00%00.0%Unchanged
Goldman Sachs Group Inc21,739$469.6K0.00%+21,739New
Trexquant Investment LP21,047$454.6K0.01%+21,047New
Rathbone Brothers plc19,906$430.0K0.00%+19,906New
Jump Financial, LLC18,800$406.1K0.01%+18,800New
Shay Capital LLC15,150$327.2K0.10%+15,150New
Bank of America Corp11,992$259.0K0.00%+10,916+1,014.5%Added
NEOS Investment Management LLC11,656$251.8K0.02%+11,656New
Advisor Group Holdings, Inc.10,922$235.8K0.00%+10,922New
JPMorgan Chase & Co9,610$207.6K0.00%+9,610New
Point72 Asset Management, L.P.8,200$177.1K0.00%+8,200New
SG Americas Securities, LLC7,000$151.0K0.00%+667+10.5%Added
Barclays PLC5,570$120.3K0.00%+5,570New
Qube Research & Technologies Ltd3,942$85.1K0.00%+3,764+2,114.6%Added
Lazard Asset Management LLC1,415$29.0K0.00%−855−37.7%Reduced
Advisors Preferred, LLC1,109$24.1K0.00%+1,109New
GAMMA Investing LLC876$18.9K0.00%−42−4.6%Reduced
Steward Partners Investment Advisory, LLC100$2.16K0.00%00.0%Unchanged
Rhumbline Advisers15$3240.00%+10+200.0%Added
BVF Inc0$00.00%−1,508,416−100.0%Sold out
Tower Research Capital LLC (TRC)0$00.00%−707−100.0%Sold out