Silence Therapeutics plc
SLN- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001479615
No open-market purchases or sales by Silence Therapeutics plc insiders were filed in the last 90 days; 72 institutions reported holding it in 13F filings for Q2 2026, worth $236.2M in total; no superinvestor holds it.
Other share classesSLNCF
13F holders, Q2 2025
Institutional positions in Silence Therapeutics plc as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 55
- −4 vs. Q1 2025
- Shares held
- 19.8M
- −2.16M (−9.8%) vs. Q1 2025
- Total value
- $108.0M
- +$47.4M (+78.2%) vs. Q1 2025
- New holders
- 9
- 12 more added
- Sold out
- 13
- 19 more reduced
Compare with Q1 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting SLN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 72 | $236.2M |
| Q1 2026 | 56 | $102.1M |
| Q4 2025 | 58 | $106.1M |
| Q3 2025 | 54 | $96.4M |
| Q2 2025 | 55 | $108.0M |
| Q1 2025 | 59 | $60.6M |
| Q4 2024 | 65 | $168.2M |
| Q3 2024 | 69 | $493.1M |
| Q2 2024 | 71 | $502.1M |
| Q1 2024 | 64 | $588.0M |
| Q4 2023 | 34 | $343.9M |
| Q3 2023 | 28 | $187.6M |
| Q2 2023 | 29 | $101.8M |
| Q1 2023 | 29 | $110.2M |
| Q4 2022 | 27 | $275.7M |
| Q3 2022 | 29 | $183.4M |
| Q2 2022 | 25 | $116.4M |
| Q1 2022 | 26 | $218.3M |
| Q4 2021 | 22 | $246.6M |
| Q3 2021 | 7 | $39.4M |
| Q2 2021 | 6 | $56.4M |
| Q1 2021 | 6 | $55.9M |
Institutions, Q2 2025
Shares, value and share of portfolio for each institution holding Silence Therapeutics plc; share changes are against Q1 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| TCG Crossover Management, LLC | 3,033,560 | $17.6M | 2.01% | 00.0% | Unchanged |
| Siren, L.L.C. | 2,911,438 | $16.9M | 0.87% | +121,605+4.4% | Added |
| Redmile Group, LLC | 2,164,777 | $12.6M | 1.34% | −50,170−2.3% | Reduced |
| Lombard Odier Asset Management (USA) Corp | 1,849,734 | $7.81M | 1.96% | 00.0% | Unchanged |
| Morgan Stanley | 1,211,758 | $7.03M | 0.00% | −788,347−39.4% | Reduced |
| Vivo Capital, LLC | 1,105,454 | $6.41M | 0.66% | 00.0% | Unchanged |
| Nantahala Capital Management, LLC | 1,042,427 | $6.05M | 0.43% | 00.0% | Unchanged |
| Frazier Life Sciences Management, L.P. | 970,130 | $5.63M | 0.23% | −178,461−15.5% | Reduced |
| Nextech Invest, Ltd. | 952,400 | $5.52M | 1.05% | 00.0% | Unchanged |
| Cantor Fitzgerald, L. P. | 789,039 | $4.58M | 0.11% | +15,194+2.0% | Added |
| 5AM Venture Management, LLC | 476,200 | $2.76M | 1.06% | 00.0% | Unchanged |
| SG Americas Securities, LLC | 308,331 | $1.79M | 0.01% | +420.0% | Added |
| Boothbay Fund Management, LLC | 252,421 | $1.46M | 0.05% | +2,409+1.0% | Added |
| Ikarian Capital, LLC | 873,568 | $1.40M | 0.46% | +873,568 | New |
| UBS Group AG | 228,509 | $1.33M | 0.00% | −91,005−28.5% | Reduced |
| Millennium Management LLC | 198,647 | $1.15M | 0.00% | −198,215−49.9% | Reduced |
| M28 Capital Management LP | 185,100 | $1.07M | 1.83% | 00.0% | Unchanged |
| HSBC Holdings PLC | 172,834 | $1.02M | 0.00% | 00.0% | Unchanged |
| Marshall Wace, LLP | 175,862 | $1.02M | 0.00% | −52,556−23.0% | Reduced |
| BlackRock, Inc. | 168,235 | $975.8K | 0.00% | −12,200−6.8% | Reduced |
| Bank of Montreal | 145,812 | $845.7K | 0.00% | −12,781−8.1% | Reduced |
| Advisor Group Holdings, Inc. | 69,381 | $402.3K | 0.00% | −2,116−3.0% | Reduced |
| Woodline Partners LP | 62,459 | $362.3K | 0.00% | −72,033−53.6% | Reduced |
| Two Sigma Investments, LP | 59,312 | $344.0K | 0.00% | −16,696−22.0% | Reduced |
| Two Sigma Advisers, LP | 39,600 | $229.7K | 0.00% | −9,600−19.5% | Reduced |
| Jane Street Group, LLC | 37,813 | $219.3K | 0.00% | +37,813 | New |
| Saturn V Capital Management LLC | 34,737 | $201.5K | 0.08% | −697,726−95.3% | Reduced |
| Geode Capital Management, LLC | 29,538 | $171.3K | 0.00% | +121+0.4% | Added |
| Susquehanna International Group, LLP | 27,797 | $161.2K | 0.00% | +27,797 | New |
| Wexford Capital LP | 27,149 | $157.5K | 0.04% | +27,149 | New |
| Massar Capital Management, LP | 19,863 | $115.2K | 0.09% | +19,863 | New |
| ADAR1 Capital Management, LLC | 18,643 | $108.1K | 0.02% | 00.0% | Unchanged |
| Rathbone Brothers plc | 18,421 | $106.8K | 0.00% | 00.0% | Unchanged |
| Virtus Investment Advisers, Inc. | 16,837 | $97.7K | 0.03% | −8,035−32.3% | Reduced |
| Beacon Pointe Advisors, LLC | 11,615 | $67.4K | 0.00% | +11,615 | New |
| Cambridge Investment Research Advisors, Inc. | 10,194 | $59.0K | 0.00% | +10,194 | New |
| China Universal Asset Management Co., Ltd. | 9,446 | $54.8K | 0.01% | +14+0.1% | Added |
| GAMMA Investing LLC | 8,333 | $48.3K | 0.00% | +4,773+134.1% | Added |
| JPMorgan Chase & Co | 7,283 | $42.2K | 0.00% | −28,131−79.4% | Reduced |
| Barclays PLC | 7,035 | $40.8K | 0.00% | +181+2.6% | Added |
| Rhumbline Advisers | 6,196 | $35.9K | 0.00% | +4,321+230.5% | Added |
| Bank of America Corp | 5,095 | $29.6K | 0.00% | −59,791−92.1% | Reduced |
| Citigroup Inc | 3,474 | $20.1K | 0.00% | −57,597−94.3% | Reduced |
| Jones Financial Companies LLLP | 2,500 | $14.5K | 0.00% | 00.0% | Unchanged |
| Tower Research Capital LLC (TRC) | 2,428 | $14.1K | 0.00% | +61+2.6% | Added |
| Royal Bank of Canada | 2,462 | $14.0K | 0.00% | −1,801−42.2% | Reduced |
| Mirae Asset Global Investments Co., Ltd. | 1,817 | $10.5K | 0.00% | +244+15.5% | Added |
| Parallel Advisors, LLC | 1,300 | $7.54K | 0.00% | 00.0% | Unchanged |
| GF Fund Management Co. Ltd. | 1,165 | $6.76K | 0.00% | 00.0% | Unchanged |
| BNP Paribas Arbitrage, SA | 700 | $4.06K | 0.00% | −4,088−85.4% | Reduced |
| Simplex Trading, LLC | 667 | $3.00K | 0.00% | +416+165.7% | Added |
| Steward Partners Investment Advisory, LLC | 100 | $580 | 0.00% | 00.0% | Unchanged |
| SBI Securities Co., Ltd. | 28 | $162 | 0.00% | 00.0% | Unchanged |
| Principal Securities, Inc. | 17 | $99 | 0.00% | +17 | New |
| EverSource Wealth Advisors, LLC | 10 | $58 | 0.00% | +10 | New |
| Parkman Healthcare Partners LLC | 0 | $0 | 0.00% | −401,746−100.0% | Sold out |
| Schonfeld Strategic Advisors LLC | 0 | $0 | 0.00% | −149,996−100.0% | Sold out |
| Walleye Capital LLC | 0 | $0 | 0.00% | −136,150−100.0% | Sold out |
| UBS Oconnor LLC | 0 | $0 | 0.00% | −62,639−100.0% | Sold out |
| Citadel Advisors LLC | 0 | $0 | 0.00% | −62,441−100.0% | Sold out |
| Shay Capital LLC | 0 | $0 | 0.00% | −47,728−100.0% | Sold out |
| Jump Financial, LLC | 0 | $0 | 0.00% | −26,351−100.0% | Sold out |
| Goldman Sachs Group Inc | 0 | $0 | 0.00% | −24,375−100.0% | Sold out |
| Qube Research & Technologies Ltd | 0 | $0 | 0.00% | −18,913−100.0% | Sold out |
| Point72 Asset Management, L.P. | 0 | $0 | 0.00% | −16,032−100.0% | Sold out |
| Acadian Asset Management LLC | 0 | $0 | 0.00% | −12,153−100.0% | Sold out |
| Cubist Systematic Strategies, LLC | 0 | $0 | 0.00% | −7,364−100.0% | Sold out |
| FNY Investment Advisers, LLC | 0 | $0 | 0.00% | −7,000−100.0% | Sold out |