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Silence Therapeutics plc

SLN
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001479615

No open-market purchases or sales by Silence Therapeutics plc insiders were filed in the last 90 days; 72 institutions reported holding it in 13F filings for Q2 2026, worth $236.2M in total; no superinvestor holds it.

Other share classesSLNCF

13F holders, Q4 2024

Institutional positions in Silence Therapeutics plc as of Dec 31, 2024. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
65
−4 vs. Q3 2024
Shares held
24.8M
−3.38M (−12.0%) vs. Q3 2024
Total value
$168.2M
−$325.0M (−65.9%) vs. Q3 2024
New holders
16
24 more added
Sold out
20
13 more reduced

Compare with Q3 2024: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting SLN on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ4 2024: 65 institutions
Q1 2021: 6 institutionsQ2 2021: 6 institutionsQ3 2021: 7 institutionsQ4 2021: 22 institutionsQ1 2022: 26 institutionsQ2 2022: 25 institutionsQ3 2022: 29 institutionsQ4 2022: 27 institutionsQ1 2023: 29 institutionsQ2 2023: 29 institutionsQ3 2023: 28 institutionsQ4 2023: 34 institutionsQ1 2024: 64 institutionsQ2 2024: 71 institutionsQ3 2024: 69 institutionsQ4 2024: 65 institutionsQ1 2025: 59 institutionsQ2 2025: 55 institutionsQ3 2025: 54 institutionsQ4 2025: 58 institutionsQ1 2026: 56 institutionsQ2 2026: 72 institutions
Value heldQ4 2024: $168.2M
Q1 2021: $55.9MQ2 2021: $56.4MQ3 2021: $39.4MQ4 2021: $246.6MQ1 2022: $218.3MQ2 2022: $116.4MQ3 2022: $183.4MQ4 2022: $275.7MQ1 2023: $110.2MQ2 2023: $101.8MQ3 2023: $187.6MQ4 2023: $343.9MQ1 2024: $588.0MQ2 2024: $502.1MQ3 2024: $493.1MQ4 2024: $168.2MQ1 2025: $60.6MQ2 2025: $108.0MQ3 2025: $96.4MQ4 2025: $106.1MQ1 2026: $102.1MQ2 2026: $236.2M
Institutions holding SLN and their total value by quarter
QuarterHoldersValue
Q2 202672$236.2M
Q1 202656$102.1M
Q4 202558$106.1M
Q3 202554$96.4M
Q2 202555$108.0M
Q1 202559$60.6M
Q4 202465$168.2M
Q3 202469$493.1M
Q2 202471$502.1M
Q1 202464$588.0M
Q4 202334$343.9M
Q3 202328$187.6M
Q2 202329$101.8M
Q1 202329$110.2M
Q4 202227$275.7M
Q3 202229$183.4M
Q2 202225$116.4M
Q1 202226$218.3M
Q4 202122$246.6M
Q3 20217$39.4M
Q2 20216$56.4M
Q1 20216$55.9M

Institutions, Q4 2024

Shares, value and share of portfolio for each institution holding Silence Therapeutics plc; share changes are against Q3 2024.

Institutions holding SLN in Q4 2024
InstitutionSharesValue% of portfolioChange in sharesAction
Simplex Trading, LLC51$00.00%+51New
Wells Fargo & Company19$1310.00%00.0%Unchanged
SBI Securities Co., Ltd.28$1930.00%+28New
Steward Partners Investment Advisory, LLC100$6880.00%00.0%Unchanged
Tower Research Capital LLC (TRC)632$4.35K0.00%+632New
Rhumbline Advisers841$5.78K0.00%+87+11.5%Added
GF Fund Management Co. Ltd.987$6.79K0.00%+987New
Royal Bank of Canada1,515$10.0K0.00%−426−21.9%Reduced
Mirae Asset Global Investments Co., Ltd.1,566$11.1K0.00%+1,566New
BNP Paribas Arbitrage, SA1,784$12.3K0.00%+1,784New
JPMorgan Chase & Co3,793$26.1K0.00%+3,793New
GAMMA Investing LLC6,092$41.9K0.00%+5,233+609.2%Added
Barclays PLC6,126$42.1K0.00%+2,793+83.8%Added
China Universal Asset Management Co., Ltd.9,963$68.5K0.01%+9,963New
Virtus ETF Advisers LLC10,772$74.1K0.03%+6,098+130.5%Added
Custom Index Systems, LLC11,861$81.6K0.04%−2,554−17.7%Reduced
Ameriprise Financial Inc16,360$112.6K0.00%+16,360New
FNY Investment Advisers, LLC17,515$120.0K0.06%+17,515New
ADAR1 Capital Management, LLC18,000$123.8K0.03%−22,290−55.3%Reduced
Rathbone Brothers plc18,421$126.7K0.00%00.0%Unchanged
Acadian Asset Management LLC19,467$133.0K0.00%+19,467New
Commonwealth of Pennsylvania Public School Empls Retrmt Sys19,467$133.9K0.00%+19,467New
Y-Intercept (Hong Kong) Ltd21,217$146.0K0.01%+139+0.7%Added
Verition Fund Management LLC24,123$166.0K0.00%+12,733+111.8%Added
Geode Capital Management, LLC29,417$202.4K0.00%00.0%Unchanged
Walleye Capital LLC36,397$250.4K0.00%+36,397New
Goldman Sachs Group Inc36,885$253.8K0.00%+6,253+20.4%Added
Advisor Group Holdings, Inc.40,867$281.0K0.00%+27,708+210.6%Added
Qube Research & Technologies Ltd54,746$376.7K0.00%+35,550+185.2%Added
Citigroup Inc60,502$416.3K0.00%+2,169+3.7%Added
Trexquant Investment LP63,663$438.0K0.01%+63,663New
Bank of Montreal65,007$447.2K0.00%−252−0.4%Reduced
Two Sigma Advisers, LP98,800$679.7K0.00%+15,500+18.6%Added
Cubist Systematic Strategies, LLC106,320$731.5K0.01%+60,015+129.6%Added
Schonfeld Strategic Advisors LLC123,200$847.6K0.01%−42,800−25.8%Reduced
UBS Oconnor LLC128,990$887.5K0.02%+43,289+50.5%Added
Two Sigma Investments, LP142,052$977.3K0.00%−27,340−16.1%Reduced
HSBC Holdings PLC172,834$1.19M0.00%−5,000−2.8%Reduced
M28 Capital Management LP185,100$1.27M1.25%00.0%Unchanged
Integral Health Asset Management, LLC200,000$1.38M0.12%+200,000New
BlackRock, Inc.211,507$1.46M0.00%+211,507New
Citadel Advisors LLC282,737$1.95M0.00%−153,960−35.3%Reduced
SG Americas Securities, LLC317,628$2.19M0.01%−25,562−7.4%Reduced
Boothbay Fund Management, LLC351,527$2.42M0.08%+180,372+105.4%Added
UBS Group AG356,071$2.45M0.00%+285,410+403.9%Added
Aquilo Capital Management, LLC367,214$2.53M4.33%+50,000+15.8%Added
Saturn V Capital Management LLC395,024$2.72M1.06%−86,103−17.9%Reduced
Millennium Management LLC473,552$3.26M0.00%−636,678−57.3%Reduced
5AM Venture Management, LLC476,200$3.28M0.78%00.0%Unchanged
Marshall Wace, LLP488,889$3.36M0.00%+320,472+190.3%Added
Parkman Healthcare Partners LLC491,080$3.38M0.45%−6,790−1.4%Reduced
Woodline Partners LP498,732$3.43M0.02%+91,829+22.6%Added
Bank of America Corp499,066$3.43M0.00%+498,032+48,165.6%Added
Cantor Fitzgerald, L. P.539,726$3.71M0.14%+205,534+61.5%Added
Point72 Asset Management, L.P.633,100$4.36M0.01%+165,300+35.3%Added
Eventide Asset Management, LLC640,000$4.40M0.08%00.0%Unchanged
Nextech Invest AG952,400$6.55M1.06%00.0%Unchanged
Nantahala Capital Management, LLC1,049,676$7.22M0.51%+849,676+424.8%Added
Vivo Capital, LLC1,105,454$7.61M0.85%00.0%Unchanged
Frazier Life Sciences Management, L.P.1,148,591$7.90M0.33%00.0%Unchanged
Lombard Odier Asset Management (USA) Corp1,856,023$10.2M3.92%−808,054−30.3%Reduced
Morgan Stanley1,663,068$11.4M0.00%+941,651+130.5%Added
Redmile Group, LLC2,399,317$16.5M1.15%+500,000+26.3%Added
Siren, L.L.C.2,831,770$19.5M0.86%00.0%Unchanged
TCG Crossover Management, LLC3,033,560$20.9M2.04%00.0%Unchanged
Janus Henderson Group PLC0$00.00%−1,087,228−100.0%Sold out
Polar Capital Holdings Plc0$00.00%−1,000,000−100.0%Sold out
Deep Track Capital, LP0$00.00%−1,000,000−100.0%Sold out
Cormorant Asset Management, LP0$00.00%−400,000−100.0%Sold out
Duquesne Family Office LLCSuperinvestorDuquesne Family Office0$00.00%−387,400−100.0%Sold out
Mangrove Partners0$00.00%−385,408−100.0%Sold out
ExodusPoint Capital Management, LP0$00.00%−338,681−100.0%Sold out
Adage Capital Partners GP, L.L.C.0$00.00%−320,000−100.0%Sold out
Soleus Capital Management, L.P.0$00.00%−260,000−100.0%Sold out
Price T Rowe Associates Inc0$00.00%−228,644−100.0%Sold out
Logos Global Management LP0$00.00%−200,000−100.0%Sold out
Ikarian Capital, LLC0$00.00%−587,343−100.0%Sold out
BIT Capital GmbH0$00.00%−92,429−100.0%Sold out
Artia Global Partners LP0$00.00%−52,476−100.0%Sold out
NEOS Investment Management LLC0$00.00%−51,712−100.0%Sold out
TD Asset Management Inc0$00.00%−30,600−100.0%Sold out
Blair William & Co0$00.00%−20,000−100.0%Sold out
Manufacturers Life Insurance Company, The0$00.00%−17,490−100.0%Sold out
Vestcor Inc0$00.00%−8,800−100.0%Sold out
Values First Advisors, Inc.0$00.00%−3,091−100.0%Sold out