Silence Therapeutics plc
SLN- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001479615
No open-market purchases or sales by Silence Therapeutics plc insiders were filed in the last 90 days; 72 institutions reported holding it in 13F filings for Q2 2026, worth $236.2M in total; no superinvestor holds it.
Other share classesSLNCF
Q4 2025 vs. Q3 2025
How the institutions holding Silence Therapeutics plc changed between Q3 2025 and Q4 2025.
All holders in Q4 2025All holders in Q3 2025
| Measure | Q3 2025 | Q4 2025 | Change |
|---|---|---|---|
| Holders | 54 | 58 | +4 |
| Shares | 19.7M | 18.1M | −1.61M (−8.2%) |
| Value | $96.4M | $106.1M | +$9.64M (+10.0%) |
New holders (14)
Institutions that held Silence Therapeutics plc at the end of Q4 2025 but not at the end of Q3 2025.
| Institution | Shares | Value | % of portfolio |
|---|---|---|---|
| Great Point Partners LLC | 808,032 | $4.91M | 1.59% |
| Polygon Management Ltd. | 365,369 | $2.22M | 0.47% |
| Ishara Investments LP | 240,000 | $1.46M | 1.70% |
| Seven Fleet Capital Management LP | 147,600 | $897.4K | 0.61% |
| Point72 Asset Management, L.P. | 114,070 | $693.5K | 0.00% |
| Opaleye Management Inc. | 78,926 | $479.9K | 0.06% |
| Quadrature Capital Ltd | 54,380 | $330.6K | 0.00% |
| Qube Research & Technologies Ltd | 34,962 | $212.6K | 0.00% |
| Jane Street Group, LLC | 29,168 | $177.3K | 0.00% |
| Raymond James Financial Inc | 25,000 | $152.0K | 0.00% |
| Susquehanna International Group, LLP | 16,866 | $102.5K | 0.00% |
| XTX Topco Ltd | 11,718 | $71.2K | 0.00% |
| Global Retirement Partners, LLC | 1,000 | $6.08K | 0.00% |
| SageView Advisory Group, LLC | 11 | $67 | 0.00% |
Sold out (10)
Institutions that held Silence Therapeutics plc at the end of Q3 2025 and filed for Q4 2025 without it.
| Institution | Shares, Q3 2025 | Value, Q3 2025 |
|---|---|---|
| Frazier Life Sciences Management, L.P. | 970,130 | $5.03M |
| Cantor Fitzgerald, L. P. | 801,306 | $4.16M |
| Woodline Partners LP | 62,459 | $324.2K |
| Virtus Investment Advisers, Inc. | 20,374 | $105.7K |
| HRT Financial LP | 10,887 | $56.0K |
| EHP Funds Inc. | 10,673 | $55.4K |
| Cambridge Investment Research Advisors, Inc. | 10,194 | $53.0K |
| Wexford Capital LP | 7,708 | $40.0K |
| Acadian Asset Management LLC | 4,218 | $21.0K |
| Principal Securities, Inc. | 17 | $88 |