| Jan 26, 2023 (view filing) | Jan 24 | 2 days | Liu Jean IChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $135.03 | −$675.1K | −5.5%85.1K after | |
| Jan 19, 2023 (view filing) | Jan 17 | 2 days | Liu Jean IChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −578 | $130.71 | −$75.6K | −0.7%85.1K after | |
| Jan 6, 2023 (view filing) | Jan 4-5 | 2 days | Dansey Roger DPresident R&D & CMO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.0K | $135.00 | −$1.35M | −9.3%97.5K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 6, 2023 (view filing) | Jan 4-5 | 2 days | Liu Jean IChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.00K | $135.00 | −$675.0K | −5.5%85.7K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 21, 2022 (view filing) | Dec 20 | 1 day | Romp Charles REVP, Commercial U.S. | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.13K | $127.63 | −$144.1K | −1.9%58.5K after | |
| Dec 16, 2022 (view filing) | Dec 14 | 2 days | Dansey Roger DPresident, Research and Develo | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.0K | $135.00 | −$1.35M | −9.3%97.5K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Nov 18, 2022 (view filing) | Nov 17 | 1 day | Liu Jean IChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.33K | $131.05 | −$1.09M | −8.9%85.7K after | |
| Nov 15, 2022 (view filing) | Nov 11 | 4 days | Gryska David WDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −7.50K | $129.10 | −$968.3K | −15.7%40.3K after | |
| Oct 19, 2022 (view filing) | Oct 17 | 2 days | Dansey Roger DInterim CEO & CMO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.0K | $135.00 | −$1.35M | −9.3%97.5K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 1, 2022 (view filing) | Aug 31 | 1 day | Simpson Todd EChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.19K | $154.41 | −$646.4K | −3.0%137.2K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 1, 2022 (view filing) | Aug 31 | 1 day | Himes Vaughn BChief Technical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.58K | $154.41 | −$553.4K | −5.1%67.2K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 1, 2022 (view filing) | Aug 31 | 1 day | Romp Charles REVP, Commercial | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.13K | $154.41 | −$174.9K | −1.9%59.6K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 1, 2022 (view filing) | Aug 31 | 1 day | Dansey Roger DInterim CEO & CMO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −5.02K | $154.41 | −$775.0K | −4.9%97.5K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Sep 1, 2022 (view filing) | Aug 31 | 1 day | Liu Jean IChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −3.65K | $154.41 | −$563.3K | −4.1%84.4K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 17, 2022 (view filing) | Aug 16 | 1 day | Simpson Todd EChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.97K | $170.22 | −$334.8K | −1.4%141.4K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 17, 2022 (view filing) | Aug 16 | 1 day | Romp Charles REVP, Commercial | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.76K | $170.22 | −$300.4K | −2.8%60.7K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 17, 2022 (view filing) | Aug 16 | 1 day | Liu Jean IChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.64K | $170.22 | −$279.0K | −1.8%88.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 17, 2022 (view filing) | Aug 16 | 1 day | Himes Vaughn BChief Technical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.53K | $170.22 | −$259.9K | −2.1%70.8K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Aug 17, 2022 (view filing) | Aug 16 | 1 day | Dansey Roger DInterim CEO & CMO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.25K | $170.22 | −$724.1K | −4.0%102.6K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Jul 7, 2022 (view filing) | Jul 5 | 2 days | Romp Charles REVP, Commercial | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −712 | $179.46 | −$127.8K | −1.4%48.8K after | |
| Jun 30, 2022 (view filing) | Jun 28 | 2 days | Dansey Roger DChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −34.6K | $180.00 | −$6.23M | −35.8%62.1K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average. |
| Jun 22, 2022 (view filing) | Jun 17 | 5 days | Himes Vaughn BChief Technical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.13K | $160.00 | −$181.4K | −0.9%119.5K after | |
| May 26, 2022 (view filing) | May 24 | 2 days | Himes Vaughn BChief Technical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −10.9K | $136.79 | −$1.49M | −15.5%59.1K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| May 18, 2022 (view filing) | May 16 | 2 days | Romp Charles REVP, Commercial | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −333 | $134.21 | −$44.7K | −0.7%49.5K after | |
| May 13, 2022 (view filing) | May 12 | 1 day | Siegall Clay BPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −17.0K | $125.69 | −$2.14M | −2.5%666.1K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Apr 22, 2022 (view filing) | Apr 20 | 2 days | Siegall Clay BPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.89K | $144.32 | −$272.0K | −0.3%666.1K after | |
| Apr 22, 2022 (view filing) | Apr 20 | 2 days | Simpson Todd EChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −567 | $144.32 | −$81.8K | −0.4%127.9K after | |
| Apr 22, 2022 (view filing) | Apr 20 | 2 days | Liu Jean IChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −401 | $144.32 | −$57.9K | −0.5%75.9K after | |
| Apr 22, 2022 (view filing) | Apr 20 | 2 days | Romp Charles REVP, Commercial | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −319 | $144.32 | −$46.0K | −0.6%49.8K after | |
| Apr 22, 2022 (view filing) | Apr 20 | 2 days | Himes Vaughn BChief Technical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −574 | $144.32 | −$82.8K | −1.0%59.1K after | |
| Apr 22, 2022 (view filing) | Apr 20-21 | 2 days | Dansey Roger DChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.44K | $144.24 | −$207.6K | −1.8%77.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Apr 21, 2022 (view filing) | Apr 19 | 2 days | Gryska David WDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.00K | $143.95 | −$575.8K | −8.0%46.3K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Apr 8, 2022 (view filing) | Apr 7 | 1 day | Siegall Clay BPresident and CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −17.0K | $154.23 | −$2.63M | −2.5%667.9K after | 7 lotsThis row combines 7 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 9, 2022 (view filing) | Mar 7 | 2 days | Siegall Clay BPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −17.0K | $134.35 | −$2.29M | −2.5%667.9K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average. |
| Mar 4, 2022 (view filing) | Mar 3 | 1 day | Himes Vaughn BChief Technical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −12.0K | $127.05 | −$1.52M | −16.8%59.5K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 9, 2022 (view filing) | Feb 7 | 2 days | Siegall Clay BPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −17.0K | $139.97 | −$2.39M | −2.5%667.9K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 9, 2022 (view filing) | Feb 7 | 2 days | Gryska David WDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.50K | $138.76 | −$624.4K | −8.9%46.3K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 4, 2022 (view filing) | Feb 2-3 | 2 days | Dansey Roger DChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.44K | $136.88 | −$197.4K | −1.8%78.2K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Feb 1, 2022 (view filing) | Jan 28 | 4 days | Gryska David WDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.50K | $122.56 | −$551.5K | −8.9%46.3K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 19, 2022 (view filing) | Jan 14 | 5 days | Gryska David WDirector | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −4.50K | $135.24 | −$608.6K | −8.9%46.3K after | |
| Jan 11, 2022 (view filing) | Jan 7 | 4 days | Siegall Clay BPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −17.0K | $144.73 | −$2.47M | −2.5%667.9K after | 4 lotsThis row combines 4 trades of the same kind from one filing. The price is the value-weighted average. |
| Jan 5, 2022 (view filing) | Jan 3 | 2 days | Dansey Roger DChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −8.68K | $152.58 | −$1.32M | −9.8%79.7K after | 3 lotsThis row combines 3 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 22, 2021 (view filing) | Dec 20 | 2 days | Romp Charles REVP, Commercial | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.32K | $149.85 | −$198.3K | −2.6%50.0K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 22, 2021 (view filing) | Dec 20 | 2 days | Himes Vaughn BChief Technical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −345 | $149.85 | −$51.7K | −0.6%59.5K after | |
| Dec 22, 2021 (view filing) | Dec 20-21 | 2 days | Dansey Roger DChief Medical Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −560 | $152.72 | −$85.5K | −0.6%88.4K after | 2 lotsThis row combines 2 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 22, 2021 (view filing) | Dec 20 | 2 days | Siegall Clay BPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −1.23K | $149.85 | −$183.9K | −0.2%667.9K after | |
| Dec 22, 2021 (view filing) | Dec 20 | 2 days | Simpson Todd EChief Financial Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −345 | $149.85 | −$51.7K | −0.3%128.5K after | |
| Dec 22, 2021 (view filing) | Dec 20 | 2 days | Liu Jean IChief Legal Officer | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −276 | $149.85 | −$41.4K | −0.4%70.4K after | |
| Dec 9, 2021 (view filing) | Dec 7 | 2 days | Siegall Clay BPresident & CEO | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −45.4K | $148.66 | −$6.76M | −6.4%669.2K after | 5 lotsThis row combines 5 trades of the same kind from one filing. The price is the value-weighted average. |
| Dec 2, 2021 (view filing)6:51 PM ET | Nov 30-Dec 1 | 2 days | Baker Julian and 5 othersDirector, 10% Owner | SSaleThe insider sold shares on the open market or in a private deal. People sell for many reasons, such as paying taxes, diversifying or following a pre-set 10b5-1 plan, so a single sale usually says less than a purchase. | −394.9K | $160.54 | −$63.4M | −0.9%42.9M after | 20 lotsThis row combines 20 trades of the same kind from one filing. The price is the value-weighted average. |
