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Puma Biotechnology, Inc.

PBYI
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001401667

In the last 90 days, Puma Biotechnology, Inc. insiders filed 0 open-market purchases and 5 sales; 160 institutions reported holding it in 13F filings for Q2 2026, worth $313.6M in total; no superinvestor holds it.

13F holders, Q1 2026

Institutional positions in Puma Biotechnology, Inc. as of Mar 31, 2026. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
157
+11 vs. Q4 2025
Shares held
37.9M
+6.34M (+20.1%) vs. Q4 2025
Total value
$241.8M
+$54.4M (+29.0%) vs. Q4 2025
New holders
29
61 more added
Sold out
18
38 more reduced

5 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q4 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PBYI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ1 2026: 157 institutions
Q1 2021: 118 institutionsQ2 2021: 120 institutionsQ3 2021: 116 institutionsQ4 2021: 102 institutionsQ1 2022: 104 institutionsQ2 2022: 89 institutionsQ3 2022: 83 institutionsQ4 2022: 89 institutionsQ1 2023: 78 institutionsQ2 2023: 68 institutionsQ3 2023: 69 institutionsQ4 2023: 82 institutionsQ1 2024: 93 institutionsQ2 2024: 99 institutionsQ3 2024: 100 institutionsQ4 2024: 112 institutionsQ1 2025: 116 institutionsQ2 2025: 121 institutionsQ3 2025: 132 institutionsQ4 2025: 151 institutionsQ1 2026: 157 institutionsQ2 2026: 160 institutions
Value heldQ1 2026: $241.8M
Q1 2021: $355.9MQ2 2021: $319.3MQ3 2021: $226.0MQ4 2021: $93.1MQ1 2022: $86.1MQ2 2022: $79.5MQ3 2022: $65.5MQ4 2022: $116.3MQ1 2023: $86.3MQ2 2023: $93.8MQ3 2023: $67.6MQ4 2023: $117.0MQ1 2024: $164.4MQ2 2024: $101.0MQ3 2024: $76.0MQ4 2024: $90.1MQ1 2025: $90.1MQ2 2025: $112.8MQ3 2025: $182.6MQ4 2025: $210.2MQ1 2026: $241.8MQ2 2026: $313.6M
Institutions holding PBYI and their total value by quarter
QuarterHoldersValue
Q2 2026160$313.6M
Q1 2026157$241.8M
Q4 2025151$210.2M
Q3 2025132$182.6M
Q2 2025121$112.8M
Q1 2025116$90.1M
Q4 2024112$90.1M
Q3 2024100$76.0M
Q2 202499$101.0M
Q1 202493$164.4M
Q4 202382$117.0M
Q3 202369$67.6M
Q2 202368$93.8M
Q1 202378$86.3M
Q4 202289$116.3M
Q3 202283$65.5M
Q2 202289$79.5M
Q1 2022104$86.1M
Q4 2021102$93.1M
Q3 2021116$226.0M
Q2 2021120$319.3M
Q1 2021118$355.9M

Institutions, Q1 2026

Shares, value and share of portfolio for each institution holding Puma Biotechnology, Inc.; share changes are against Q4 2025.

Institutions holding PBYI in Q1 2026
InstitutionSharesValue% of portfolioChange in sharesAction
Universal- Beteiligungs- und Servicegesellschaft mbH39,308$251.2K0.00%00.0%Unchanged
Bank of America Corp40,364$257.9K0.00%−12,021−22.9%Reduced
Man Group plc47,375$302.7K0.00%+51+0.1%Added
D'Orazio & Associates, Inc.49,915$319.0K0.04%+108+0.2%Added
Rhumbline Advisers53,036$338.9K0.00%−859−1.6%Reduced
EntryPoint Capital, LLC53,464$341.6K0.10%+18,075+51.1%Added
Nomura Asset Management International Inc.61,255$391.0K0.00%00.0%Unchanged
Winton Group Ltd66,333$423.9K0.01%−30,826−31.7%Reduced
State of Wyoming75,808$484.4K0.06%+22,653+42.6%Added
Nuveen, LLC79,101$505.5K0.00%00.0%Unchanged
OpenArc Corporate Advisory, LLC89,491$571.8K0.01%+130+0.1%Added
STRS Ohio91,500$584.7K0.00%−7,900−7.9%Reduced
Invesco Ltd.95,044$607.3K0.00%−13,257−12.2%Reduced
Evergreen Capital Management LLC96,000$613.4K0.01%00.0%Unchanged
Charles Schwab Investment Management Inc115,915$740.7K0.00%−9,457−7.5%Reduced
First Trust Advisors LP123,513$789.2K0.00%+713+0.6%Added
Round Rock Advisors, LLC128,912$823.7K0.13%+23,870+22.7%Added
Haven Private, LLC155,260$992.1K0.43%+63,177+68.6%Added
Prospera Financial Services Inc173,051$1.11M0.02%−12,445−6.7%Reduced
FMR LLC191,833$1.23M0.00%+27,963+17.1%Added
Panagora Asset Management Inc194,887$1.25M0.00%00.0%Unchanged
Empowered Funds, LLC204,041$1.30M0.01%+17,856+9.6%Added
State of Wisconsin Investment Board208,618$1.33M0.00%+74,844+55.9%Added
JPMorgan Chase & Co220,724$1.35M0.00%+199,616+945.7%Added
Franklin Resources Inc215,391$1.38M0.00%+32,685+17.9%Added
Federated Hermes, Inc.237,715$1.52M0.00%−142−0.1%Reduced
Russell Investments Group, Ltd.251,653$1.61M0.00%00.0%Unchanged
Vanguard Fiduciary Trust Co251,683$1.61M0.00%+251,683New
Prudential Financial Inc253,039$1.62M0.00%−33,470−11.7%Reduced
State Board of Administration of Florida Retirement System272,890$1.74M0.00%+245,555+898.3%Added
Bank of New York Mellon Corp347,881$2.22M0.00%−4,000−1.1%Reduced
Globeflex Capital L P349,651$2.23M0.34%−102,955−22.7%Reduced
D. E. Shaw & Co., Inc.351,235$2.24M0.00%−27,061−7.2%Reduced
Morgan Stanley359,742$2.30M0.00%+32,968+10.1%Added
SEI Investments Co508,182$3.25M0.00%+78,257+18.2%Added
UBS Group AG534,227$3.41M0.00%+406,915+319.6%Added
Arrowstreet Capital, Limited Partnership538,155$3.44M0.00%−9,698−1.8%Reduced
Northern Trust Corp641,753$4.10M0.00%+25,556+4.1%Added
Goldman Sachs Group Inc669,719$4.28M0.00%−124,243−15.6%Reduced
Ritholtz Wealth Management774,308$4.95M0.09%+80,307+11.6%Added
Bridgeway Capital Management, LLC775,341$4.95M0.10%+1,856+0.2%Added
Connor, Clark & Lunn Investment Management Ltd.782,798$5.00M0.01%−92,503−10.6%Reduced
AQR Capital Management LLC800,194$5.11M0.00%+133,589+20.0%Added
Kennedy Capital Management, Inc.889,601$5.68M0.12%+21,286+2.5%Added
State Street Corp917,590$5.86M0.00%+40,513+4.6%Added
Geode Capital Management, LLC1,017,342$6.50M0.00%+22,997+2.3%Added
O'Shaughnessy Asset Management, LLC1,138,169$7.27M0.04%+17,840+1.6%Added
LSV Asset Management1,182,868$7.56M0.02%+778,066+192.2%Added
Dimensional Fund Advisors LP1,436,106$9.17M0.00%+96,503+7.2%Added
Millennium Management LLC1,477,519$9.44M0.01%+1,460,905+8,793.2%Added
Vanguard Portfolio Management LLC1,734,649$11.1M0.00%+1,734,649New
Vanguard Capital Management LLC1,817,681$11.6M0.00%+1,817,681New
American Century Companies Inc1,916,346$12.2M0.01%+266,209+16.1%Added
Renaissance Technologies LLC1,942,413$12.4M0.02%−181,400−8.5%Reduced
Acadian Asset Management LLC2,041,759$13.0M0.02%+16,936+0.8%Added
BlackRock, Inc.3,598,952$23.0M0.00%−43,636−1.2%Reduced
Acorn Capital Advisors, LLC4,131,299$26.4M7.50%00.0%Unchanged
Mackenzie Financial Corp0$00.00%−160,973−100.0%Sold out
Los Angeles Capital Management LLC0$00.00%−148,132−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−111,520−100.0%Sold out
Two Sigma Advisers, LP0$00.00%−71,100−100.0%Sold out
Verdad Advisers, LP0$00.00%−55,542−100.0%Sold out
Jane Street Group, LLC0$00.00%−36,362−100.0%Sold out
Heron Bay Capital Management0$00.00%−20,056−100.0%Sold out
Intech Investment Management LLC0$00.00%−18,900−100.0%Sold out
Axq Capital, LP0$00.00%−16,592−100.0%Sold out
Headlands Technologies LLC0$00.00%−15,976−100.0%Sold out
Causeway Capital Management LLC0$00.00%−13,310−100.0%Sold out
PFG Investments, LLC0$00.00%−12,000−100.0%Sold out
Royce & Associates LP0$00.00%−11,914−100.0%Sold out
ProShare Advisors LLC0$00.00%−10,062−100.0%Sold out
Amalgamated Bank0$00.00%−1,353−100.0%Sold out
DecisionPoint Financial, LLC0$00.00%−100−100.0%Sold out
Clearstead Advisors, LLC0$00.00%−17−100.0%Sold out
National Bank of Canada0$00.00%−10−100.0%Sold out
Vanguard Group Inc––––Not filed
Brandywine Global Investment Management, LLC––––Not filed
Global Retirement Partners, LLC––––Not filed
GPS Wealth Strategies Group, LLC––––Not filed
CIBC Private Wealth Group, LLC––––Not filed