Puma Biotechnology, Inc.

PBYI

Exchange: Nasdaq
Industry: Pharmaceutical Preparations
SEC CIK: 0001401667

SEC filings (opens in a new tab)

In the last 90 days, Puma Biotechnology, Inc. insiders filed 0 open-market purchases and 5 sales; 160 institutions reported holding it in 13F filings for Q2 2026, worth $313.6M in total; no superinvestor holds it.

Q1 2026 vs. Q4 2025

How the institutions holding Puma Biotechnology, Inc. changed between Q4 2025 and Q1 2026.

All holders in Q1 2026 All holders in Q4 2025

13F holders of PBYI: Q4 2025 compared with Q1 2026
Measure	Q4 2025	Of which not filed for Q1 2026	Q1 2026	Change
Holders	151	5	157	+11
Shares	35.3M	3.82M	37.9M	+6.34M (+20.1%)
Value	$210.2M	$22.7M	$241.8M	+$54.4M (+29.0%)

5 institutions that held it in Q4 2025 haven't filed for Q1 2026 yet. Not filing isn't selling, so the changes leave them out.

New holders (29)

Institutions that held Puma Biotechnology, Inc. at the end of Q1 2026 but not at the end of Q4 2025.

Institutions new to PBYI in Q1 2026
Institution	Shares	Value	% of portfolio
Vanguard Capital Management LLC	1,817,681	$11.6M	0.00%
Vanguard Portfolio Management LLC	1,734,649	$11.1M	0.00%
Vanguard Fiduciary Trust Co	251,683	$1.61M	0.00%
Deutsche Bank AG	33,145	$211.8K	0.00%
Vanguard Global Advisers, LLC	29,173	$186.4K	0.00%
Envestnet Asset Management Inc	26,558	$169.7K	0.00%
Creative Planning	23,113	$147.7K	0.00%
Bailard, Inc.	18,100	$115.7K	0.00%
Allspring Global Investments Holdings, LLC	17,066	$109.1K	0.00%
Quadrature Capital Ltd	16,745	$107.0K	0.00%
Susquehanna International Group, LLP	16,089	$102.8K	0.00%
XTX Topco Ltd	15,116	$96.6K	0.00%
Mariner, LLC	14,649	$93.6K	0.00%
Ashton Thomas Private Wealth, LLC	13,500	$86.3K	0.00%
HRT Financial LP	13,073	$83.0K	0.00%
Tocqueville Asset Management L.P.	12,960	$82.8K	0.00%
Abacus Wealth Partners, LLC	11,199	$71.6K	0.01%
DGS Capital Management, LLC	10,418	$66.6K	0.01%
Philadelphia Investment Partners, LLC	9,000	$57.5K	0.04%
UBS Asset Management Americas Inc	1,710	$10.9K	0.00%
Intentional Wealth Strategies, LLC	1,128	$7.21K	0.01%
Harbour Investments, Inc.	500	$3.19K	0.00%
Root Financial Partners, LLC	269	$1.72K	0.00%
Frazier Financial Advisors, LLC	183	$1.17K	0.00%
Mosley Wealth Management	148	$786	0.00%
Basecamp Wealth Advisors LLC	86	$550	0.00%
Fifth Third Bancorp	8	$51	0.00%
TFC Financial Management	1	$7	0.00%
Wealth Preservation Advisors, LLC	1	$6	0.00%

Sold out (18)

Institutions that held Puma Biotechnology, Inc. at the end of Q4 2025 and filed for Q1 2026 without it.

Institutions that sold out of PBYI in Q1 2026
Institution	Shares, Q4 2025	Value, Q4 2025
Mackenzie Financial Corp	160,973	$965.5K
Los Angeles Capital Management LLC	148,132	$808.8K
Qube Research & Technologies Ltd	111,520	$663.5K
Two Sigma Advisers, LP	71,100	$423.0K
Verdad Advisers, LP	55,542	$330.5K
Jane Street Group, LLC	36,362	$216.4K
Heron Bay Capital Management	20,056	$119.3K
Intech Investment Management LLC	18,900	$112.5K
Axq Capital, LP	16,592	$98.7K
Headlands Technologies LLC	15,976	$95.1K
Causeway Capital Management LLC	13,310	$79.2K
PFG Investments, LLC	12,000	$71.4K
Royce & Associates LP	11,914	$70.9K
ProShare Advisors LLC	10,062	$59.9K
Amalgamated Bank	1,353	$8.00K
DecisionPoint Financial, LLC	100	$595
Clearstead Advisors, LLC	17	$102
National Bank of Canada	10	$59

Not filed for Q1 2026 yet (5)

Institutions that held Puma Biotechnology, Inc. at the end of Q4 2025 and haven't filed a 13F for Q1 2026. Not filing isn't selling, so they aren't counted as sold out.

Institutions holding PBYI in Q4 2025 that haven't filed for Q1 2026
Institution	Shares, Q4 2025	Value, Q4 2025
Vanguard Group Inc	3,797,748	$22.6M
Brandywine Global Investment Management, LLC	21,800	$129.7K
Global Retirement Partners, LLC	1,492	$8.88K
GPS Wealth Strategies Group, LLC	1,000	$5.95K
CIBC Private Wealth Group, LLC	775	$4.61K