Puma Biotechnology, Inc.
PBYI- Exchange
- Nasdaq
- Industry
- Pharmaceutical Preparations
- SEC CIK
- 0001401667
In the last 90 days, Puma Biotechnology, Inc. insiders filed 0 open-market purchases and 5 sales; 160 institutions reported holding it in 13F filings for Q2 2026, worth $313.6M in total; no superinvestor holds it.
13F holders, Q4 2025
Institutional positions in Puma Biotechnology, Inc. as of Dec 31, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works
- Institutional holders
- 151
- +19 vs. Q3 2025
- Shares held
- 35.3M
- +964.7K (+2.8%) vs. Q3 2025
- Total value
- $210.2M
- +$27.7M (+15.2%) vs. Q3 2025
- New holders
- 33
- 52 more added
- Sold out
- 14
- 38 more reduced
Compare with Q3 2025: new holders, sold out and not filed yet
Holders and value by quarter
Institutions reporting PBYI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.
| Quarter | Holders | Value |
|---|---|---|
| Q2 2026 | 160 | $313.6M |
| Q1 2026 | 157 | $241.8M |
| Q4 2025 | 151 | $210.2M |
| Q3 2025 | 132 | $182.6M |
| Q2 2025 | 121 | $112.8M |
| Q1 2025 | 116 | $90.1M |
| Q4 2024 | 112 | $90.1M |
| Q3 2024 | 100 | $76.0M |
| Q2 2024 | 99 | $101.0M |
| Q1 2024 | 93 | $164.4M |
| Q4 2023 | 82 | $117.0M |
| Q3 2023 | 69 | $67.6M |
| Q2 2023 | 68 | $93.8M |
| Q1 2023 | 78 | $86.3M |
| Q4 2022 | 89 | $116.3M |
| Q3 2022 | 83 | $65.5M |
| Q2 2022 | 89 | $79.5M |
| Q1 2022 | 104 | $86.1M |
| Q4 2021 | 102 | $93.1M |
| Q3 2021 | 116 | $226.0M |
| Q2 2021 | 120 | $319.3M |
| Q1 2021 | 118 | $355.9M |
Institutions, Q4 2025
Shares, value and share of portfolio for each institution holding Puma Biotechnology, Inc.; share changes are against Q3 2025.
| Institution | Shares | Value | % of portfolio | Change in shares | Action |
|---|---|---|---|---|---|
| Canada Pension Plan Investment Board | 75,200 | $447.4K | 0.00% | +75,200 | New |
| Nuveen, LLC | 79,101 | $470.7K | 0.00% | 00.0% | Unchanged |
| Barclays PLC | 81,434 | $484.5K | 0.00% | +1,553+1.9% | Added |
| OpenArc Corporate Advisory, LLC | 89,361 | $531.7K | 0.01% | +89,361 | New |
| Haven Private, LLC | 92,083 | $547.9K | 0.24% | +92,083 | New |
| Evergreen Capital Management LLC | 96,000 | $571.2K | 0.01% | 00.0% | Unchanged |
| Winton Group Ltd | 97,159 | $578.1K | 0.02% | +35,835+58.4% | Added |
| STRS Ohio | 99,400 | $591.4K | 0.00% | −25,500−20.4% | Reduced |
| Round Rock Advisors, LLC | 105,042 | $625.0K | 0.09% | +39,646+60.6% | Added |
| Invesco Ltd. | 108,301 | $644.4K | 0.00% | +44,484+69.7% | Added |
| Qube Research & Technologies Ltd | 111,520 | $663.5K | 0.00% | −43,996−28.3% | Reduced |
| First Trust Advisors LP | 122,800 | $730.7K | 0.00% | +3,021+2.5% | Added |
| Charles Schwab Investment Management Inc | 125,372 | $746.0K | 0.00% | 00.0% | Unchanged |
| UBS Group AG | 127,312 | $757.5K | 0.00% | −248,779−66.1% | Reduced |
| State of Wisconsin Investment Board | 133,774 | $796.0K | 0.00% | +79,456+146.3% | Added |
| Los Angeles Capital Management LLC | 148,132 | $808.8K | 0.00% | −125,918−45.9% | Reduced |
| Mackenzie Financial Corp | 160,973 | $965.5K | 0.00% | −14,237−8.1% | Reduced |
| Two Sigma Investments, LP | 162,351 | $966.0K | 0.00% | +106,225+189.3% | Added |
| Citadel Advisors LLC | 162,670 | $967.9K | 0.00% | +162,670 | New |
| FMR LLC | 163,870 | $975.0K | 0.00% | +18,585+12.8% | Added |
| Franklin Resources Inc | 182,706 | $1.09M | 0.00% | +9,008+5.2% | Added |
| Prospera Financial Services Inc | 185,496 | $1.10M | 0.02% | −4,123−2.2% | Reduced |
| Empowered Funds, LLC | 186,185 | $1.11M | 0.02% | +66,624+55.7% | Added |
| Panagora Asset Management Inc | 194,887 | $1.16M | 0.00% | +28,966+17.5% | Added |
| Federated Hermes, Inc. | 237,857 | $1.42M | 0.00% | +39,876+20.1% | Added |
| Russell Investments Group, Ltd. | 251,653 | $1.50M | 0.00% | −713,040−73.9% | Reduced |
| Prudential Financial Inc | 286,509 | $1.70M | 0.00% | +65,565+29.7% | Added |
| Morgan Stanley | 326,774 | $1.94M | 0.00% | −51,308−13.6% | Reduced |
| Bank of New York Mellon Corp | 351,881 | $2.09M | 0.00% | −3,487−1.0% | Reduced |
| D. E. Shaw & Co., Inc. | 378,296 | $2.25M | 0.00% | −120,302−24.1% | Reduced |
| LSV Asset Management | 404,802 | $2.41M | 0.01% | −155,119−27.7% | Reduced |
| SEI Investments Co | 429,925 | $2.56M | 0.00% | +82,691+23.8% | Added |
| Globeflex Capital L P | 452,606 | $2.69M | 0.41% | 00.0% | Unchanged |
| Arrowstreet Capital, Limited Partnership | 547,853 | $3.26M | 0.00% | +83,119+17.9% | Added |
| Northern Trust Corp | 616,197 | $3.67M | 0.00% | +89,461+17.0% | Added |
| AQR Capital Management LLC | 666,605 | $3.97M | 0.00% | +535,933+410.1% | Added |
| Ritholtz Wealth Management | 694,001 | $4.13M | 0.08% | +223,234+47.4% | Added |
| Bridgeway Capital Management, LLC | 773,485 | $4.60M | 0.10% | +339,924+78.4% | Added |
| Goldman Sachs Group Inc | 793,962 | $4.72M | 0.00% | +559,345+238.4% | Added |
| Kennedy Capital Management, Inc. | 868,315 | $5.17M | 0.11% | +685+0.1% | Added |
| Connor, Clark & Lunn Investment Management Ltd. | 875,301 | $5.21M | 0.01% | −68,171−7.2% | Reduced |
| State Street Corp | 877,077 | $5.22M | 0.00% | +128,419+17.2% | Added |
| Geode Capital Management, LLC | 994,345 | $5.92M | 0.00% | +10,823+1.1% | Added |
| O'Shaughnessy Asset Management, LLC | 1,120,329 | $6.67M | 0.04% | +292,108+35.3% | Added |
| Dimensional Fund Advisors LP | 1,339,603 | $7.97M | 0.00% | +67,725+5.3% | Added |
| American Century Companies Inc | 1,650,137 | $9.82M | 0.00% | +166,949+11.3% | Added |
| Acadian Asset Management LLC | 2,024,823 | $12.0M | 0.02% | −28,482−1.4% | Reduced |
| Renaissance Technologies LLC | 2,123,813 | $12.6M | 0.02% | −27,400−1.3% | Reduced |
| BlackRock, Inc. | 3,642,588 | $21.7M | 0.00% | +64,711+1.8% | Added |
| Vanguard Group Inc | 3,797,748 | $22.6M | 0.00% | +106,028+2.9% | Added |
| Acorn Capital Advisors, LLC | 4,131,299 | $24.6M | 8.33% | 00.0% | Unchanged |
| Marshall Wace, LLP | 0 | $0 | 0.00% | −557,548−100.0% | Sold out |
| Tang Capital Management LLC | 0 | $0 | 0.00% | −200,000−100.0% | Sold out |
| Wellington Management Group LLP | 0 | $0 | 0.00% | −149,552−100.0% | Sold out |
| Hillsdale Investment Management Inc. | 0 | $0 | 0.00% | −77,800−100.0% | Sold out |
| Assenagon Asset Management S.A. | 0 | $0 | 0.00% | −72,979−100.0% | Sold out |
| Macquarie Group Ltd | 0 | $0 | 0.00% | −61,255−100.0% | Sold out |
| Graham Capital Management, L.P. | 0 | $0 | 0.00% | −52,708−100.0% | Sold out |
| Deutsche Bank AG | 0 | $0 | 0.00% | −30,743−100.0% | Sold out |
| Sherbrooke Park Advisers LLC | 0 | $0 | 0.00% | −30,527−100.0% | Sold out |
| XTX Topco Ltd | 0 | $0 | 0.00% | −25,524−100.0% | Sold out |
| Sanctuary Advisors, LLC | 0 | $0 | 0.00% | −23,866−100.0% | Sold out |
| Squarepoint Ops LLC | 0 | $0 | 0.00% | −21,334−100.0% | Sold out |
| Luminist Capital LLC | 0 | $0 | 0.00% | −250−100.0% | Sold out |
| Atlantic Union Bankshares Corp | 0 | $0 | 0.00% | −150−100.0% | Sold out |