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Puma Biotechnology, Inc.

PBYI
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001401667

In the last 90 days, Puma Biotechnology, Inc. insiders filed 0 open-market purchases and 5 sales; 160 institutions reported holding it in 13F filings for Q2 2026, worth $313.6M in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Puma Biotechnology, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
121
+6 vs. Q1 2025
Shares held
32.9M
+2.48M (+8.1%) vs. Q1 2025
Total value
$112.8M
+$22.8M (+25.3%) vs. Q1 2025
New holders
22
42 more added
Sold out
16
32 more reduced

1 institution that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PBYI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 121 institutions
Q1 2021: 118 institutionsQ2 2021: 120 institutionsQ3 2021: 116 institutionsQ4 2021: 102 institutionsQ1 2022: 104 institutionsQ2 2022: 89 institutionsQ3 2022: 83 institutionsQ4 2022: 89 institutionsQ1 2023: 78 institutionsQ2 2023: 68 institutionsQ3 2023: 69 institutionsQ4 2023: 82 institutionsQ1 2024: 93 institutionsQ2 2024: 99 institutionsQ3 2024: 100 institutionsQ4 2024: 112 institutionsQ1 2025: 116 institutionsQ2 2025: 121 institutionsQ3 2025: 132 institutionsQ4 2025: 151 institutionsQ1 2026: 157 institutionsQ2 2026: 160 institutions
Value heldQ2 2025: $112.8M
Q1 2021: $355.9MQ2 2021: $319.3MQ3 2021: $226.0MQ4 2021: $93.1MQ1 2022: $86.1MQ2 2022: $79.5MQ3 2022: $65.5MQ4 2022: $116.3MQ1 2023: $86.3MQ2 2023: $93.8MQ3 2023: $67.6MQ4 2023: $117.0MQ1 2024: $164.4MQ2 2024: $101.0MQ3 2024: $76.0MQ4 2024: $90.1MQ1 2025: $90.1MQ2 2025: $112.8MQ3 2025: $182.6MQ4 2025: $210.2MQ1 2026: $241.8MQ2 2026: $313.6M
Institutions holding PBYI and their total value by quarter
QuarterHoldersValue
Q2 2026160$313.6M
Q1 2026157$241.8M
Q4 2025151$210.2M
Q3 2025132$182.6M
Q2 2025121$112.8M
Q1 2025116$90.1M
Q4 2024112$90.1M
Q3 2024100$76.0M
Q2 202499$101.0M
Q1 202493$164.4M
Q4 202382$117.0M
Q3 202369$67.6M
Q2 202368$93.8M
Q1 202378$86.3M
Q4 202289$116.3M
Q3 202283$65.5M
Q2 202289$79.5M
Q1 2022104$86.1M
Q4 2021102$93.1M
Q3 2021116$226.0M
Q2 2021120$319.3M
Q1 2021118$355.9M

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Puma Biotechnology, Inc.; share changes are against Q1 2025.

Institutions holding PBYI in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Bank of New York Mellon Corp344,083$1.18M0.00%+3,197+0.9%Added
SEI Investments Co347,234$1.19M0.00%−445−0.1%Reduced
O'Shaughnessy Asset Management, LLC437,660$1.50M0.01%+329,715+305.4%Added
Los Angeles Capital Management LLC445,477$1.53M0.01%+38,623+9.5%Added
Arrowstreet Capital, Limited Partnership451,633$1.55M0.00%+93,012+25.9%Added
Globeflex Capital L P452,606$1.55M0.13%00.0%Unchanged
Citadel Advisors LLC507,818$1.74M0.00%+507,818New
LSV Asset Management535,740$1.84M0.00%+482,340+903.3%Added
D. E. Shaw & Co., Inc.640,780$2.20M0.00%+69,115+12.1%Added
State Street Corp734,606$2.52M0.00%+84,814+13.1%Added
Janus Henderson Group PLC745,541$2.56M0.00%+745,541New
Connor, Clark & Lunn Investment Management Ltd.900,256$3.09M0.01%+68,567+8.2%Added
Geode Capital Management, LLC971,674$3.33M0.00%+16,218+1.7%Added
Kennedy Capital Management, Inc.987,001$3.39M0.08%+75,878+8.3%Added
Dimensional Fund Advisors LP1,150,040$3.94M0.00%+261,377+29.4%Added
American Century Companies Inc1,342,275$4.60M0.00%+192,615+16.8%Added
Renaissance Technologies LLC1,874,713$6.43M0.01%+45,500+2.5%Added
Acadian Asset Management LLC2,008,146$6.88M0.01%00.0%Unchanged
Vanguard Group Inc3,706,452$12.7M0.00%+37,189+1.0%Added
BlackRock, Inc.3,835,715$13.2M0.00%−11,653−0.3%Reduced
Acorn Capital Advisors, LLC4,131,299$14.2M9.27%+191,247+4.9%Added
Gsa Capital Partners LLP0$00.00%−99,394−100.0%Sold out
Integrated Quantitative Investments LLC0$00.00%−59,727−100.0%Sold out
Man Group plc0$00.00%−37,469−100.0%Sold out
Virtu Financial LLC0$00.00%−31,477−100.0%Sold out
Bailard, Inc.0$00.00%−24,702−100.0%Sold out
Dynamic Technology Lab Private Ltd0$00.00%−22,030−100.0%Sold out
Corebridge Financial, Inc.0$00.00%−20,618−100.0%Sold out
Oxford Asset Management LLP0$00.00%−17,647−100.0%Sold out
Walleye Capital LLC0$00.00%−13,055−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−12,752−100.0%Sold out
Quadrature Capital Ltd0$00.00%−12,508−100.0%Sold out
Sherbrooke Park Advisers LLC0$00.00%−12,224−100.0%Sold out
Patriot Financial Group Insurance Agency, LLC0$00.00%−10,500−100.0%Sold out
Gateway Wealth Partners, LLC0$00.00%−10,200−100.0%Sold out
Lazard Asset Management LLC0$00.00%−2,100−100.0%Sold out
Coldstream Capital Management Inc0$00.00%−304−100.0%Sold out
CAPROCK Group, Inc.––––Not filed