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Puma Biotechnology, Inc.

PBYI
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001401667

In the last 90 days, Puma Biotechnology, Inc. insiders filed 0 open-market purchases and 5 sales; 160 institutions reported holding it in 13F filings for Q2 2026, worth $313.6M in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Puma Biotechnology, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
121
+6 vs. Q1 2025
Shares held
32.9M
+2.48M (+8.1%) vs. Q1 2025
Total value
$112.8M
+$22.8M (+25.3%) vs. Q1 2025
New holders
22
42 more added
Sold out
16
32 more reduced

1 institution that held it in Q1 2025 haven't filed for Q2 2025 yet. Not filing isn't selling, so they aren't counted as sold out or in the changes above.

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting PBYI on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 121 institutions
Q1 2021: 118 institutionsQ2 2021: 120 institutionsQ3 2021: 116 institutionsQ4 2021: 102 institutionsQ1 2022: 104 institutionsQ2 2022: 89 institutionsQ3 2022: 83 institutionsQ4 2022: 89 institutionsQ1 2023: 78 institutionsQ2 2023: 68 institutionsQ3 2023: 69 institutionsQ4 2023: 82 institutionsQ1 2024: 93 institutionsQ2 2024: 99 institutionsQ3 2024: 100 institutionsQ4 2024: 112 institutionsQ1 2025: 116 institutionsQ2 2025: 121 institutionsQ3 2025: 132 institutionsQ4 2025: 151 institutionsQ1 2026: 157 institutionsQ2 2026: 160 institutions
Value heldQ2 2025: $112.8M
Q1 2021: $355.9MQ2 2021: $319.3MQ3 2021: $226.0MQ4 2021: $93.1MQ1 2022: $86.1MQ2 2022: $79.5MQ3 2022: $65.5MQ4 2022: $116.3MQ1 2023: $86.3MQ2 2023: $93.8MQ3 2023: $67.6MQ4 2023: $117.0MQ1 2024: $164.4MQ2 2024: $101.0MQ3 2024: $76.0MQ4 2024: $90.1MQ1 2025: $90.1MQ2 2025: $112.8MQ3 2025: $182.6MQ4 2025: $210.2MQ1 2026: $241.8MQ2 2026: $313.6M
Institutions holding PBYI and their total value by quarter
QuarterHoldersValue
Q2 2026160$313.6M
Q1 2026157$241.8M
Q4 2025151$210.2M
Q3 2025132$182.6M
Q2 2025121$112.8M
Q1 2025116$90.1M
Q4 2024112$90.1M
Q3 2024100$76.0M
Q2 202499$101.0M
Q1 202493$164.4M
Q4 202382$117.0M
Q3 202369$67.6M
Q2 202368$93.8M
Q1 202378$86.3M
Q4 202289$116.3M
Q3 202283$65.5M
Q2 202289$79.5M
Q1 2022104$86.1M
Q4 2021102$93.1M
Q3 2021116$226.0M
Q2 2021120$319.3M
Q1 2021118$355.9M

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Puma Biotechnology, Inc.; share changes are against Q1 2025.

Institutions holding PBYI in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Allworth Financial LP1$40.00%+1New
ZRC Wealth Management, LLC3$110.00%00.0%Unchanged
Russell Investments Group, Ltd.20$690.00%−20,873−99.9%Reduced
SBI Securities Co., Ltd.56$1920.00%00.0%Unchanged
IFP Advisors, Inc40$1990.00%+26+185.7%Added
South State Corp.111$3810.00%00.0%Unchanged
True Wealth Design, LLC127$4360.00%−15−10.6%Reduced
EverSource Wealth Advisors, LLC161$5520.00%+155+2,583.3%Added
US Bancorp200$6860.00%00.0%Unchanged
Luminist Capital LLC250$8980.00%+250New
Clearstead Advisors, LLC335$1.15K0.00%+335New
Nisa Investment Advisors, LLC342$1.17K0.00%−75−18.0%Reduced
Essential Partners LLC439$1.51K0.00%+439New
Fourth Dimension Wealth, LLC500$1.72K0.00%−200−28.6%Reduced
CIBC Private Wealth Group, LLC775$2.66K0.00%00.0%Unchanged
GPS Wealth Strategies Group, LLC1,000$3.43K0.00%00.0%Unchanged
Sterling Capital Management LLC1,145$3.93K0.00%+640+126.7%Added
WealthCollab, LLC1,156$3.97K0.00%+845+271.7%Added
GHP Investment Advisors, Inc.1,170$4.01K0.00%00.0%Unchanged
Rialto Wealth Management, LLC1,450$4.97K0.00%00.0%Unchanged
Amalgamated Bank1,432$5.00K0.00%00.0%Unchanged
Global Retirement Partners, LLC1,492$5.12K0.00%+1,492New
Headlands Technologies LLC1,538$5.28K0.00%+321+26.4%Added
California State Teachers Retirement System2,999$10.3K0.00%00.0%Unchanged
Ball & Co Wealth Management Inc.3,506$12.0K0.01%00.0%Unchanged
Private Wealth Asset Management, LLC3,500$12.0K0.00%+1,500+75.0%Added
Legal & General Group Plc3,564$12.2K0.00%−348−8.9%Reduced
New York State Common Retirement Fund3,600$12.3K0.00%00.0%Unchanged
Ameritas Investment Partners, Inc.4,055$13.9K0.00%00.0%Unchanged
BNP Paribas Arbitrage, SA5,766$19.8K0.00%−71,562−92.5%Reduced
Police & Firemen's Retirement System of New Jersey8,322$28.5K0.00%00.0%Unchanged
Tower Research Capital LLC (TRC)8,469$29.0K0.00%+5,403+176.2%Added
CWM, LLC9,462$32.0K0.00%+6,450+214.1%Added
Cerity Partners LLC10,528$36.1K0.00%+10,528New
Williams & Novak, LLC12,520$42.9K0.04%−2,200−14.9%Reduced
Voya Investment Management LLC12,976$44.5K0.00%−11,756−47.5%Reduced
Alliancebernstein L.P.13,800$47.3K0.00%+13,800New
Causeway Capital Management LLC14,095$48.3K0.00%00.0%Unchanged
Ieq Capital, LLC14,305$49.1K0.00%+14,305New
Citigroup Inc14,320$49.1K0.00%−15,147−51.4%Reduced
Ethic Inc.15,168$50.5K0.00%+15,168New
D'Orazio & Associates, Inc.15,027$51.5K0.01%+15,027New
Manufacturers Life Insurance Company, The15,576$53.4K0.00%−930−5.6%Reduced
Royce & Associates LP17,285$59.3K0.00%−1,440−7.7%Reduced
Franklin Resources Inc17,691$60.7K0.00%−60,484−77.4%Reduced
Squarepoint Ops LLC17,794$61.0K0.00%+17,794New
Advisor Group Holdings, Inc.17,944$61.5K0.00%+450+2.6%Added
HSBC Holdings PLC19,751$66.6K0.00%−758−3.7%Reduced
Price T Rowe Associates Inc19,566$68.0K0.00%00.0%Unchanged
PFG Investments, LLC20,000$68.6K0.00%00.0%Unchanged
Kathmere Capital Management, LLC20,204$69.3K0.01%+20,204New
JPMorgan Chase & Co20,245$69.4K0.00%−28,107−58.1%Reduced
C2C Wealth Management, LLC20,620$70.7K0.06%+5,470+36.1%Added
Intech Investment Management LLC20,823$71.4K0.00%−9,681−31.7%Reduced
Mirae Asset Global ETFs Holdings Ltd.23,765$81.5K0.00%−1,092−4.4%Reduced
MetLife Investment Management27,158$93.2K0.00%+37+0.1%Added
Wells Fargo & Company28,026$96.1K0.00%+4,578+19.5%Added
Deutsche Bank AG30,743$105.4K0.00%00.0%Unchanged
Prelude Capital Management, LLC33,422$114.6K0.01%−4,278−11.3%Reduced
Empowered Funds, LLC38,292$131.3K0.00%+38,292New
Universal- Beteiligungs- und Servicegesellschaft mbH39,308$134.8K0.00%00.0%Unchanged
Jane Street Group, LLC39,448$135.3K0.00%+39,448New
Invesco Ltd.49,982$171.4K0.00%+12,351+32.8%Added
LPL Financial LLC53,293$182.8K0.00%+10,000+23.1%Added
Virtus ETF Advisers LLC55,431$190.1K0.12%00.0%Unchanged
Metis Global Partners, LLC55,798$191.4K0.00%+13,040+30.5%Added
Susquehanna International Group, LLP57,724$198.0K0.00%−15,147−20.8%Reduced
Rhumbline Advisers60,611$207.9K0.00%+22,316+58.3%Added
Macquarie Group Ltd61,255$210.0K0.00%00.0%Unchanged
Bank of America Corp67,242$230.6K0.00%−25,845−27.8%Reduced
Kapitalo Investimentos Ltda70,269$241.0K0.05%+70,269New
State Board of Administration of Florida Retirement System71,727$246.0K0.00%+71,727New
Marshall Wace, LLP73,415$251.8K0.00%−142,998−66.1%Reduced
Panagora Asset Management Inc76,684$263.0K0.00%+76,684New
Nuveen, LLC79,101$271.3K0.00%00.0%Unchanged
Hillsdale Investment Management Inc.84,800$290.9K0.01%+84,800New
Evergreen Capital Management LLC96,000$329.3K0.01%+96,000New
XTX Topco Ltd104,424$358.2K0.01%−20,893−16.7%Reduced
Barclays PLC108,653$372.7K0.00%+25,392+30.5%Added
Charles Schwab Investment Management Inc127,443$437.1K0.00%+9,189+7.8%Added
FMR LLC132,364$454.0K0.00%+5,190+4.1%Added
Qube Research & Technologies Ltd137,079$470.2K0.00%−15,864−10.4%Reduced
AQR Capital Management LLC141,773$486.3K0.00%+91,315+181.0%Added
STRS Ohio147,300$505.2K0.00%+5,400+3.8%Added
Royal Bank of Canada153,270$524.0K0.00%+67,271+78.2%Added
Two Sigma Investments, LP190,621$653.8K0.00%−2,179−1.1%Reduced
Prospera Financial Services Inc191,244$655.9K0.01%+6,987+3.8%Added
Ritholtz Wealth Management196,985$675.7K0.01%+196,985New
Tang Capital Management LLC200,000$686.0K0.03%00.0%Unchanged
Goldman Sachs Group Inc202,029$693.0K0.00%−92,214−31.3%Reduced
Federated Hermes, Inc.202,335$694.0K0.00%+1,373+0.7%Added
Bridgeway Capital Management, LLC202,790$695.6K0.02%+121,690+150.0%Added
Mackenzie Financial Corp207,591$712.0K0.00%+49,878+31.6%Added
Eversept Partners, LP240,688$825.6K0.08%−35,100−12.7%Reduced
Two Sigma Advisers, LP245,700$842.8K0.00%−1,100−0.4%Reduced
UBS Group AG274,100$940.2K0.00%−5,567−2.0%Reduced
Prudential Financial Inc281,244$964.7K0.00%−26,911−8.7%Reduced
Northern Trust Corp302,015$1.04M0.00%−15,423−4.9%Reduced
Morgan Stanley322,462$1.11M0.00%+59,924+22.8%Added
Millennium Management LLC334,609$1.15M0.00%−1,050,585−75.8%Reduced