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Structure Therapeutics Inc.

GPCR
Exchange
Nasdaq
Industry
Pharmaceutical Preparations
SEC CIK
0001888886

No open-market purchases or sales by Structure Therapeutics Inc. insiders were filed in the last 90 days; 191 institutions reported holding it in 13F filings for Q2 2026, worth $3.62B in total; no superinvestor holds it.

13F holders, Q2 2025

Institutional positions in Structure Therapeutics Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
173
+22 vs. Q1 2025
Shares held
54.8M
−1.57M (−2.8%) vs. Q1 2025
Total value
$1.14B
+$147.5M (+14.9%) vs. Q1 2025
New holders
38
63 more added
Sold out
16
44 more reduced

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting GPCR on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 173 institutions
Q1 2021: 0 institutionsQ2 2021: 0 institutionsQ3 2021: 0 institutionsQ4 2021: 0 institutionsQ1 2022: 0 institutionsQ2 2022: 0 institutionsQ3 2022: 0 institutionsQ4 2022: 0 institutionsQ1 2023: 38 institutionsQ2 2023: 48 institutionsQ3 2023: 84 institutionsQ4 2023: 122 institutionsQ1 2024: 119 institutionsQ2 2024: 167 institutionsQ3 2024: 161 institutionsQ4 2024: 165 institutionsQ1 2025: 151 institutionsQ2 2025: 173 institutionsQ3 2025: 158 institutionsQ4 2025: 199 institutionsQ1 2026: 198 institutionsQ2 2026: 191 institutions
Value heldQ2 2025: $1.14B
Q1 2021: $0Q2 2021: $0Q3 2021: $0Q4 2021: $0Q1 2022: $0Q2 2022: $0Q3 2022: $0Q4 2022: $0Q1 2023: $346.2MQ2 2023: $699.4MQ3 2023: $1.64BQ4 2023: $1.74BQ1 2024: $1.86BQ2 2024: $2.33BQ3 2024: $2.69BQ4 2024: $1.65BQ1 2025: $990.0MQ2 2025: $1.14BQ3 2025: $1.59BQ4 2025: $4.58BQ1 2026: $3.23BQ2 2026: $3.62B
Institutions holding GPCR and their total value by quarter
QuarterHoldersValue
Q2 2026191$3.62B
Q1 2026198$3.23B
Q4 2025199$4.58B
Q3 2025158$1.59B
Q2 2025173$1.14B
Q1 2025151$990.0M
Q4 2024165$1.65B
Q3 2024161$2.69B
Q2 2024167$2.33B
Q1 2024119$1.86B
Q4 2023122$1.74B
Q3 202384$1.64B
Q2 202348$699.4M
Q1 202338$346.2M
Q4 20220$0
Q3 20220$0
Q2 20220$0
Q1 20220$0
Q4 20210$0
Q3 20210$0
Q2 20210$0
Q1 20210$0

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding Structure Therapeutics Inc.; share changes are against Q1 2025.

Institutions holding GPCR in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Boothbay Fund Management, LLC57,622$1.20M0.04%−19,672−25.5%Reduced
Macquarie Group Ltd58,000$1.20M0.00%00.0%Unchanged
DAFNA Capital Management LLC59,000$1.22M0.34%00.0%Unchanged
Bank of Montreal58,073$1.22M0.00%+4,838+9.1%Added
Exchange Traded Concepts, LLC61,732$1.28M0.02%+22,809+58.6%Added
Jump Financial, LLC63,234$1.31M0.02%+32,524+105.9%Added
Advisor Group Holdings, Inc.63,362$1.31M0.00%+31,972+101.9%Added
BNP Paribas Arbitrage, SA65,836$1.37M0.00%+61,318+1,357.2%Added
Jain Global LLC69,369$1.44M0.02%+45,730+193.5%Added
Banque Pictet & Cie SA70,401$1.46M0.02%−11,365−13.9%Reduced
Cubist Systematic Strategies, LLC71,690$1.49M0.02%+16,874+30.8%Added
Verition Fund Management LLC72,984$1.51M0.01%+53,402+272.7%Added
Platinum Investment Management Ltd74,900$1.55M0.10%00.0%Unchanged
Susquehanna International Group, LLP75,802$1.57M0.00%+7,635+11.2%Added
Trexquant Investment LP81,588$1.69M0.02%−38,752−32.2%Reduced
HighVista Strategies LLC86,621$1.80M0.66%+69,060+393.3%Added
Sphera Funds Management Ltd.95,931$1.99M0.52%+11,931+14.2%Added
Eversept Partners, LP99,338$2.06M0.21%+99,338New
Renaissance Technologies LLC111,900$2.32M0.00%+96,100+608.2%Added
Point72 Europe (London) LLP116,697$2.42M0.12%+26,000+28.7%Added
First Light Asset Management, LLC122,226$2.53M0.33%−10,154−7.7%Reduced
Rhenman & Partners Asset Management AB135,100$2.80M0.35%+65,100+93.0%Added
Susquehanna Fundamental Investments, LLC139,717$2.90M0.08%−18,244−11.5%Reduced
CCG Wealth Management, LLC150,000$3.11M1.64%00.0%Unchanged
UBS Group AG152,981$3.17M0.00%−85,216−35.8%Reduced
Canada Pension Plan Investment Board167,800$3.48M0.00%+167,800New
Nantahala Capital Management, LLC168,553$3.50M0.25%00.0%Unchanged
Silverarc Capital Management, LLC175,636$3.64M0.75%−12,433−6.6%Reduced
Marshall Wace, LLP176,060$3.65M0.00%+145,434+474.9%Added
Woodline Partners LP176,453$3.66M0.02%+1,029+0.6%Added
Readystate Asset Management LP178,612$3.70M0.15%−302,629−62.9%Reduced
Ikarian Capital, LLC183,085$3.80M1.26%−81,000−30.7%Reduced
Schroder Investment Management Group187,805$3.90M0.00%−288,331−60.6%Reduced
Pier Capital, LLC198,478$4.12M0.63%−14,042−6.6%Reduced
Foresite Capital Management VI LLC210,000$4.36M2.45%−210,000−50.0%Reduced
Goldman Sachs Group Inc220,174$4.57M0.00%−104,261−32.1%Reduced
BlackRock, Inc.243,334$5.05M0.00%−323,171−57.0%Reduced
SC China Holding Ltd266,062$5.52M0.28%00.0%Unchanged
ArrowMark Colorado Holdings LLC298,937$6.20M0.11%+53,751+21.9%Added
Schonfeld Strategic Advisors LLC321,591$6.67M0.05%+321,591New
Point72 Asset Management, L.P.330,000$6.84M0.02%+100,569+43.8%Added
Bellevue Group AG348,527$7.23M0.16%+126,812+57.2%Added
Price T Rowe Associates Inc352,868$7.32M0.00%−424,305−54.6%Reduced
Deerfield Management Company, L.P. (Series C)373,407$7.74M0.14%00.0%Unchanged
Handelsbanken Fonder AB380,000$7.88M0.03%00.0%Unchanged
Standard Life Aberdeen plc401,624$8.33M0.01%+152,725+61.4%Added
Invesco Ltd.424,548$8.81M0.00%+30,162+7.6%Added
Monashee Investment Management LLC430,000$8.92M4.71%+137,138+46.8%Added
Pacific Heights Asset Management LLC460,000$9.54M0.51%+460,000New
Federated Hermes, Inc.468,300$9.71M0.02%−702,648−60.0%Reduced
American Century Companies Inc491,193$10.2M0.01%−19,008−3.7%Reduced
Catalio Capital Management, LP670,575$13.9M2.92%−34,289−4.9%Reduced
Driehaus Capital Management LLC672,792$14.0M0.11%−599,951−47.1%Reduced
Franklin Resources Inc741,783$15.4M0.00%+1,631+0.2%Added
Logos Global Management LP850,000$17.6M2.35%+425,000+100.0%Added
Principal Financial Group Inc853,202$17.7M0.01%+96,495+12.8%Added
Morgan Stanley917,346$19.0M0.00%+224,907+32.5%Added
TCG Crossover Management, LLC1,063,000$22.0M2.52%00.0%Unchanged
Rock Springs Capital Management LP1,135,879$23.6M1.47%+2,900+0.3%Added
OrbiMed Advisors LLC1,199,300$24.9M0.63%+547,272+83.9%Added
Vestal Point Capital, LP1,200,000$24.9M1.31%−588,990−32.9%Reduced
Millennium Management LLC1,220,055$25.3M0.02%+429,896+54.4%Added
Casdin Capital, LLC1,225,000$25.4M2.31%+525,000+75.0%Added
Citadel Advisors LLC1,328,479$27.6M0.02%+336,139+33.9%Added
Ra Capital Management, L.P.1,517,418$31.5M0.53%00.0%Unchanged
Ameriprise Financial Inc1,588,198$32.9M0.01%+106,389+7.2%Added
Capital International Investors1,618,876$33.6M0.01%−1500.0%Reduced
BVF Inc1,771,417$36.7M1.31%00.0%Unchanged
Baker Bros. Advisors LP2,508,767$52.0M0.50%+2,147,202+593.9%Added
Janus Henderson Group PLC4,573,006$94.9M0.05%+217,812+5.0%Added
FMR LLC4,914,965$101.9M0.01%−968,742−16.5%Reduced
Deep Track Capital, LP5,133,917$106.5M3.42%+1,033,917+25.2%Added
Wellington Management Group LLP6,875,769$142.6M0.03%−915,414−11.7%Reduced
Capital Research Global Investors0$00.00%−2,164,145−100.0%Sold out
FIL Ltd0$00.00%−1,150,440−100.0%Sold out
Camber Capital Management LP0$00.00%−300,000−100.0%Sold out
Candriam Luxembourg S.C.A.0$00.00%−214,063−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−202,483−100.0%Sold out
Jane Street Group, LLC0$00.00%−120,703−100.0%Sold out
Zimmer Partners, LP0$00.00%−100,776−100.0%Sold out
Wexford Capital LP0$00.00%−30,102−100.0%Sold out
HRT Financial LP0$00.00%−22,859−100.0%Sold out
Graham Capital Management, L.P.0$00.00%−11,908−100.0%Sold out
Penserra Capital Management LLC0$00.00%−3,411−100.0%Sold out
Boston Private Wealth LLC0$00.00%−836−100.0%Sold out
CoreCap Advisors, LLC0$00.00%−77−100.0%Sold out
Clearstead Advisors, LLC0$00.00%−67−100.0%Sold out
Mather Group, LLC.0$00.00%−35−100.0%Sold out
Larson Financial Group LLC0$00.00%−9−100.0%Sold out