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89bio, Inc.

ETNBDelisted Oct 30, 2025
Industry
Pharmaceutical Preparations
SEC CIK
0001785173

89bio, Inc. was delisted on Oct 30, 2025; its insiders filed their last Form 4 on Nov 3, 2025; 198 institutions reported holding it in 13F filings for Q3 2025, worth $2.27B in total; no superinvestor held it.

13F holders, Q2 2025

Institutional positions in 89bio, Inc. as of Jun 30, 2025. Investment managers with $100 million or more in US stocks report their long positions on Form 13F within 45 days after each quarter ends. How 13F works

Institutional holders
185
−2 vs. Q1 2025
Shares held
161.2M
+6.86M (+4.4%) vs. Q1 2025
Total value
$1.58B
+$444.2M (+39.0%) vs. Q1 2025
New holders
31
80 more added
Sold out
33
56 more reduced

Compare with Q1 2025: new holders, sold out and not filed yet

Holders and value by quarter

Institutions reporting ETNB on Form 13F each quarter since Q1 2021, and the total value they reported. Values are as of each quarter end, so they also move with the share price.

Institutional holdersQ2 2025: 185 institutions
Q1 2021: 67 institutionsQ2 2021: 49 institutionsQ3 2021: 48 institutionsQ4 2021: 50 institutionsQ1 2022: 69 institutionsQ2 2022: 70 institutionsQ3 2022: 86 institutionsQ4 2022: 106 institutionsQ1 2023: 147 institutionsQ2 2023: 157 institutionsQ3 2023: 160 institutionsQ4 2023: 153 institutionsQ1 2024: 150 institutionsQ2 2024: 145 institutionsQ3 2024: 144 institutionsQ4 2024: 156 institutionsQ1 2025: 187 institutionsQ2 2025: 185 institutionsQ3 2025: 198 institutionsQ4 2025: 2 institutionsQ1 2026: 0 institutionsQ2 2026: 0 institutions
Value heldQ2 2025: $1.58B
Q1 2021: $400.6MQ2 2021: $315.2MQ3 2021: $339.4MQ4 2021: $226.1MQ1 2022: $64.3MQ2 2022: $104.6MQ3 2022: $227.3MQ4 2022: $589.5MQ1 2023: $1.08BQ2 2023: $1.46BQ3 2023: $1.11BQ4 2023: $1.05BQ1 2024: $1.14BQ2 2024: $828.4MQ3 2024: $773.8MQ4 2024: $948.7MQ1 2025: $1.14BQ2 2025: $1.58BQ3 2025: $2.27BQ4 2025: $1.11MQ1 2026: $0Q2 2026: $0
Institutions holding ETNB and their total value by quarter
QuarterHoldersValue
Q2 20260$0
Q1 20260$0
Q4 20252$1.11M
Q3 2025198$2.27B
Q2 2025185$1.58B
Q1 2025187$1.14B
Q4 2024156$948.7M
Q3 2024144$773.8M
Q2 2024145$828.4M
Q1 2024150$1.14B
Q4 2023153$1.05B
Q3 2023160$1.11B
Q2 2023157$1.46B
Q1 2023147$1.08B
Q4 2022106$589.5M
Q3 202286$227.3M
Q2 202270$104.6M
Q1 202269$64.3M
Q4 202150$226.1M
Q3 202148$339.4M
Q2 202149$315.2M
Q1 202167$400.6M

Institutions, Q2 2025

Shares, value and share of portfolio for each institution holding 89bio, Inc.; share changes are against Q1 2025.

Institutions holding ETNB in Q2 2025
InstitutionSharesValue% of portfolioChange in sharesAction
Alliancebernstein L.P.112,430$1.10M0.00%−41,396−26.9%Reduced
Caption Management, LLC114,401$1.12M0.10%−66,199−36.7%Reduced
Verition Fund Management LLC121,162$1.19M0.01%+121,162New
Algert Global LLC121,981$1.20M0.03%−65,010−34.8%Reduced
Rafferty Asset Management, LLC122,353$1.20M0.00%−14,894−10.9%Reduced
Susquehanna Portfolio Strategies, LLC126,508$1.24M0.03%+102,408+424.9%Added
Ameriprise Financial Inc138,410$1.36M0.00%+138,410New
State of Wisconsin Investment Board148,001$1.45M0.00%+29,296+24.7%Added
American Century Companies Inc149,018$1.46M0.00%−36,277−19.6%Reduced
Invesco Ltd.151,696$1.49M0.00%+35,945+31.1%Added
Comerica Bank188,003$1.85M0.01%−70,120−27.2%Reduced
Rhumbline Advisers193,818$1.90M0.00%+41,680+27.4%Added
Swiss National Bank195,200$1.92M0.00%−10,300−5.0%Reduced
Orchard Capital Managment, LLC198,119$1.95M2.15%−266,239−57.3%Reduced
Newtyn Management, LLC200,000$1.96M0.30%00.0%Unchanged
Sphera Funds Management Ltd.205,675$2.02M0.53%−412,668−66.7%Reduced
Atom Investors LP205,947$2.02M0.18%+112,780+121.1%Added
Hennion & Walsh Asset Management, Inc.211,955$2.08M0.08%+71,649+51.1%Added
Superstring Capital Management LP212,377$2.09M2.60%+103,221+94.6%Added
Citigroup Inc216,325$2.12M0.00%+9,195+4.4%Added
Harbor Capital Advisors, Inc.217,752$2.14M0.09%−97,020−30.8%Reduced
F/M Investments LLC217,742$2.14M0.08%+2,905+1.4%Added
Hudson Bay Capital Management LP225,700$2.22M0.01%−24,500−9.8%Reduced
Royce & Associates LP226,058$2.22M0.02%+80.0%Added
Exome Asset Management LLC233,426$2.29M1.89%−120,456−34.0%Reduced
Jennison Associates LLC234,190$2.30M0.00%+234,190New
Eversept Partners, LP235,990$2.32M0.23%−67,741−22.3%Reduced
Two Sigma Investments, LP254,109$2.50M0.00%+65,660+34.8%Added
Voya Investment Management LLC254,256$2.50M0.00%+121,465+91.5%Added
Susquehanna Fundamental Investments, LLC255,796$2.51M0.07%−10,670−4.0%Reduced
Royal Bank of Canada260,641$2.56M0.00%+193,953+290.8%Added
Dark Forest Capital Management LP266,395$2.62M0.11%+205,974+340.9%Added
Trexquant Investment LP281,027$2.76M0.03%+181,844+183.3%Added
Apis Capital Advisors, LLC322,000$3.16M1.12%+7,000+2.2%Added
Susquehanna International Group, LLP329,861$3.24M0.00%+161,751+96.2%Added
Panagora Asset Management Inc329,881$3.24M0.01%−99,511−23.2%Reduced
UBS Group AG349,445$3.43M0.00%+146,238+72.0%Added
Bank of New York Mellon Corp349,572$3.43M0.00%+39,656+12.8%Added
Wellington Management Group LLP367,267$3.61M0.00%+117,074+46.8%Added
Vivo Capital, LLC376,804$3.70M0.38%00.0%Unchanged
Schonfeld Strategic Advisors LLC383,188$3.76M0.03%+383,188New
UBS Asset Management Americas Inc391,410$3.84M0.00%+122,612+45.6%Added
Barclays PLC488,711$4.80M0.00%−338,149−40.9%Reduced
Infinitum Asset Management, LLC500,000$4.91M1.09%00.0%Unchanged
Renaissance Technologies LLC513,400$5.04M0.01%+9,100+1.8%Added
FMR LLC569,005$5.59M0.00%−121,007−17.5%Reduced
Raymond James Financial Inc571,602$5.61M0.00%+189,311+49.5%Added
Alyeska Investment Group, L.P.576,973$5.67M0.02%−275,254−32.3%Reduced
Nuveen, LLC638,827$6.27M0.00%−397,130−38.3%Reduced
Candriam Luxembourg S.C.A.766,211$7.52M0.04%−65,612−7.9%Reduced
ADAR1 Capital Management, LLC875,983$8.60M1.40%+71,763+8.9%Added
Erste Asset Management GmbH883,000$8.68M0.07%00.0%Unchanged
Readystate Asset Management LP902,076$8.86M0.37%+216,907+31.7%Added
Millennium Management LLC962,474$9.45M0.01%+510,020+112.7%Added
Integral Health Asset Management, LLC1,050,000$10.3M0.96%00.0%Unchanged
Charles Schwab Investment Management Inc1,063,972$10.4M0.00%+78,201+7.9%Added
Northern Trust Corp1,132,437$11.1M0.00%+46,973+4.3%Added
Emerald Mutual Fund Advisers Trust1,145,813$11.3M0.69%+62,840+5.8%Added
University of Wisconsin Foundation1,153,357$11.3M12.67%00.0%Unchanged
Dimensional Fund Advisors LP1,183,223$11.6M0.00%+595,237+101.2%Added
Woodline Partners LP1,222,661$12.0M0.06%+521,907+74.5%Added
Bank of America Corp1,249,954$12.3M0.00%+468,002+59.9%Added
Goldman Sachs Group Inc1,253,085$12.3M0.00%+257,636+25.9%Added
Redmile Group, LLC1,545,208$15.2M1.61%−341,236−18.1%Reduced
Emerald Advisers, LLC1,844,370$18.1M0.66%+293,699+18.9%Added
RTW Investments, LP1,967,527$19.3M0.28%00.0%Unchanged
Adage Capital Partners GP, L.L.C.1,969,000$19.3M0.03%+1,969,000New
Silverarc Capital Management, LLC2,037,087$20.0M4.09%+526,589+34.9%Added
Assenagon Asset Management S.A.2,171,194$21.3M0.03%+1,742,299+406.2%Added
Morgan Stanley2,185,005$21.5M0.00%+1,555,776+247.3%Added
Point72 Asset Management, L.P.2,274,151$22.3M0.05%+2,274,151New
Polar Capital Holdings Plc2,475,000$24.3M0.13%−25,000−1.0%Reduced
Holocene Advisors, LP3,065,387$30.1M0.07%+3,065,387New
Geode Capital Management, LLC3,111,299$30.6M0.00%+213,325+7.4%Added
Westfield Capital Management Co LP3,370,817$33.1M0.14%−523,924−13.5%Reduced
Citadel Advisors LLC3,836,892$37.7M0.03%−1,249,944−24.6%Reduced
Pictet Asset Management Holding SA4,035,390$39.6M0.04%−169,497−4.0%Reduced
State Street Corp4,249,957$41.7M0.00%+219,650+5.4%Added
Avoro Capital Advisors LLC6,750,000$66.3M1.16%+400,000+6.3%Added
Vanguard Group Inc8,242,154$80.9M0.00%+1,078,545+15.1%Added
Deep Track Capital, LP9,500,000$93.3M3.00%+183,667+2.0%Added
BlackRock, Inc.10,569,424$103.8M0.00%+494,080+4.9%Added
Suvretta Capital Management, LLC14,210,000$139.5M5.26%−125,244−0.9%Reduced
Ra Capital Management, L.P.19,889,683$195.3M3.29%00.0%Unchanged
Janus Henderson Group PLC20,788,363$204.2M0.10%+325,458+1.6%Added
Logos Global Management LP0$00.00%−2,500,000−100.0%Sold out
Beck Bode, LLC0$00.00%−1,815,524−100.0%Sold out
Lord, Abbett & Co. LLC0$00.00%−733,404−100.0%Sold out
Sio Capital Management, LLC0$00.00%−500,000−100.0%Sold out
Balyasny Asset Management LLC0$00.00%−336,649−100.0%Sold out
Laurion Capital Management LP0$00.00%−292,467−100.0%Sold out
Jefferies Financial Group Inc.0$00.00%−181,000−100.0%Sold out
Qube Research & Technologies Ltd0$00.00%−176,834−100.0%Sold out
Affinity Asset Advisors, LLC0$00.00%−175,000−100.0%Sold out
Ghisallo Capital Management LLC0$00.00%−175,000−100.0%Sold out
Ikarian Capital, LLC0$00.00%−100,000−100.0%Sold out
Jacobs Levy Equity Management, Inc0$00.00%−98,848−100.0%Sold out
B Group, Inc.0$00.00%−95,623−100.0%Sold out
Jain Global LLC0$00.00%−88,482−100.0%Sold out
PDT Partners, LLC0$00.00%−66,088−100.0%Sold out